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Personal and social factors influencing age at first sexual intercourse.

Early initiation of sexual activity is a concern, in part because of increased risk of sexually transmitted diseases, including HIV, and unwanted pregnancies among young people. In this study, 241 high schoolers were administered a questionnaire to establish the relationships between age at first sexual intercourse and personal qualities (sexual style, attractiveness, physical maturity, restraint, autonomy expectations, and attitudes to gender roles), smoking and drug use, and aspects of the social context (social activities, media impact, peer norms). There were few effects of sex of respondent and none in which respondents' sex impacted on age of initiation. Overall (and among the male sample), perceptions of greater physical maturity, greater use of uncommon (mostly illicit) drugs, and expectations of earlier autonomy significantly differentiated between early and later initiators. This group of factors tends to confirm the view that early experience of sexual intercourse is correlated with problem behaviors and a press toward "adult" behaviors. For girls, this pattern was even clearer, with use of uncommon drugs being replaced as a significant contributor to early sexual experience by relative lack of restraint. We conclude that the desire to achieve the transition to adulthood at an earlier age than their peers constitutes a powerful incentive for young people to become sexually active.

Adolescent↗

Secular trends in risk behaviour of Cape Town grade 8 students.

OBJECTIVE: To compare prevalence rates of selected risk behaviours and age of first intercourse of grade 8 students in Cape Town between 1997 and 2004. DESIGN: Cross-sectional surveys in 1997 and 2004. Survival analysis was used to estimate the cumulative incidence of first intercourse. The log-rank statistic was used to compare the survival distributions. When comparing data from the two studies we used a logistic regression model with the factors year, race and age group to test the difference in reported risk behaviours between 1997 and 2004 within each gender. SETTING: Public high schools in Cape Town. SUBJECTS: Multistage cluster samples of 1 437 and 6 266 grade 8 students in 1997 and 2004 respectively. OUTCOME MEASURES: Ever having had sexual intercourse; for those that had, whether any method was used to prevent pregnancy or disease at last intercourse, and (if so) what was used; use of tobacco, alcohol and marijuana; violence-related behaviours; and suicidal behaviour. RESULTS: There was a significant delay in first intercourse in 2004 compared with 1997. For males, levels of condom use were lower in 2004 than in 1997, while for females levels of injectable contraceptive use were lower. There were significant increases in past month use of cigarettes for males and marijuana for both genders. Rates of perpetration of violence behaviour remained stable or decreased from 1997 to 2004, while the rate of suicidal behaviour for males increased. CONCLUSIONS: School-based interventions that address sexual risk behaviours should be expanded to include other risk behaviours.

Adolescent↗

Predictors of rape in the Central African Republic.

This is a study of women in the Central African Republic (CAR) whose first sexual encounter was the result of rape. The analyses presented here are based on a national HIV/AIDS survey conducted in 1989. Respondents were selected through multistage cluster sampling, where census districts and households within districts were randomly selected. A total of 1307 females responded to the question regarding the circumstances of their first intercourse. Nearly 22% of female respondents reported that their first experience with intercourse was rape. Bivariate analyses found that rape during first intercourse was significantly related to the following respondent characteristics at the time of the survey: age, marital status, having a child, education, occupation, urban versus rural living, ethnic group, age at first date, and consumption of alcohol. Rape was not significantly related to ability to read, religion, and years in current village or town. Rape during first intercourse was found in a stepwise logistic regression to be related to age, marital status, occupation, and ethnic group. These data indicate that the incidence of rape is higher than previously reported in Africa, there are specific risk factors, and there are serious negative consequences.

Adolescent↗

[Adolescent sexuality in rural Norway 1997-2001].

BACKGROUND: In order to understand and prevent unwanted health consequences related to sexual behaviour, we need to know the status and changes of sexual behaviour in adolescence. MATERIAL AND METHOD: In 1997 and 2001, surveys were conducted including a total of 1665 adolescents and young adults aged 15 to 24 (response rate > 90%) in secondary schools in a small town in a rural district in Norway. We analysed frequencies for boys and girls and estimated the change in median age of first intercourse. Logistic regression analyses of median age and other health-related parameters were performed. RESULTS: A greater proportion of the respondents reported sexual experience in 2001 than in 1997. Girls have their first intercourse at a younger age than boys, often with older partners. 21% of the girls had experienced unwanted sexual situations. Use of contraception has increased, though insignificantly. Still, 11% of sexually active girls had had unwanted pregnancies. First intercourse during adolescence is clearly associated with other forms of behaviour that compromise health. However, a great and stable majority report a stable partner during adolescence. CONCLUSIONS: In accordance with other studies we find changes in sexual behaviour over a short period of time among adolescents in rural Norway. Stable sexual relations may still be a protective factor.

Adolescent↗

Contraception and sexuality in an area-specific group of Swedish women 15-34 years of age.

In a community-based study in a Swedish suburban/rural area, all women aged 15-34 years (n = 671) were invited to the local health centre to be examined for chlamydia infection and for an interview. The attenders were asked about contraceptive history, age at first intercourse, number of life-time sexual partners and socioeconomic background. The net attendance was 69%, and contraceptive information on an additional 20% could be gathered through medical records. The average age at first intercourse was around 16 years, and the average number of sexual partners in the age-groups 20-24, 25-30 and 31-34 years was 4.0, 5.6 and 6.1, respectively. Of all women, around 75% had used contraception at first intercourse, and there was no tendency to a changing pattern during the past 20 years studies through the interviews. Combined estrogen-progestagen pills were by far the most used contraceptive method, presently being used by 42% of the contracepting women, followed by condom (23%), IUD (19%) and other hormonal methods (10%). It is concluded that sexual life in Sweden starts earlier than it did 30 years ago, that the number of sexual partners is higher, that most women in the studied group were efficient contraceptors, and that hormonal contraception was by far the most common method.

Adolescent↗

Risk of high-grade cervical intraepithelial neoplasia among young women with abnormal screening cytology.

OBJECTIVE: To estimate the risk of high-grade cervical disease among teenage women with abnormal cytology. METHODS: Retrospective analysis of a prospectively collected database of females undergoing colposcopy for abnormal screening cytology in an urban dysplasia clinic. RESULTS: Among 211 eligible teens, high-grade squamous intraepithelial lesions were found in 17 (8%) on referral cytology and 4 (2%) on repeat cytology. High-grade cervical intraepithelial neoplasia was found in colposcopic biopsy specimens 30 (15%) of young women; no patient had cancer. Age, referral Pap, ethnicity, parity, HIV serostatus, history of other sexually transmitted infections, smoking, oral contraceptive use condom use, use of medroxyprogesterone, age at first intercourse, and the number of years since first intercourse did not predict increasing risk of high-grade cervical intraepithelial neoplasia (CIN). In logistic regression, both number of partners > or = 5 (p = 0.003) and a finding of any squamous intraepithelial lesion in a Pap test repeated at colposcopy (p = 0.025) were significant predictors of CIN 2,3, though the predictive value of the model was weak (R = 0.12). CONCLUSION: Only 15% of teens with abnormal cytology have high-grade CIN. Colposcopy may be most appropriate for those with multiple partners and squamous intraepithelial lesions on repeat Pap.

Adolescent↗

Sexual behaviour of Cape Town high-school students.

OBJECTIVES: To document prevalence rates for selected aspects of sexual behaviour among Cape Town high-school students and to conduct a survival analysis of age at first intercourse. DESIGN: Cross-sectional survey. SETTING: State high schools in Cape Town. SUBJECTS: A multistage cluster sample of 2,740 grade 8 and 11 students at 39 schools. OUTCOME MEASURES: Ever having had sexual intercourse; for those who had, age at first intercourse, number of partners during the previous 12 months, time since last intercourse; and, at last intercourse, whether the partner had been known for more than 7 days, whether any method was used to prevent pregnancy or disease, and (if so) what was used. RESULTS: Overall, 29.9% had participated in sexual intercourse, with a higher proportion among males and those in grade 11. By the age of 14 years, 23.4% of males and 5.5% of females had participated in sexual intercourse. By the age of 19 years, these proportions were 71.8% and 58.2% respectively. The median time since last intercourse was 4 weeks, the median number of partners in the past year was 1, and 78.4% had known their most recent partner for more than 7 days. At their last coital episode, 65.4% had used contraception, and the most common methods were condoms and injectable steroids, which were used by 67.7% and 43.2% respectively. CONCLUSIONS: The proportion of sexually active students has increased since 1990. Intervention programmes should commence in primary school. Large numbers of students are at risk for pregnancy and sexually transmitted infections.

Adolescent↗

Sexual initiation with older male partners and subsequent HIV risk behavior among female adolescents.

Data from a 1993-1994 survey of 150 black and Hispanic teenagers were used to examine differences in HIV risk-related behavior between young women who have a first sexual partner three or more years older than themselves and those whose first partner is their age. Compared with teenagers whose first partner had been roughly their age, the 35% of adolescents with an older partner had been younger at first intercourse (13.8 years vs. 14.6) and less likely to use a condom at first intercourse (63% vs. 82%). They also were less likely to report having used a condom at last intercourse (29% vs. 44%) or having used condoms consistently over their lifetime (37% vs. 56%) or in the previous six months (44% vs. 66%). Some 38% of teenagers with an older first partner had ever been pregnant, compared with 12% of those with a peer-age first partner. The mean number of partners and history of sexually transmitted diseases did not differ between the two groups.

Adolescent↗

[Contraception during the first sexual intercourse: a survey concerning 467 female teenagers, 13 to 21 years in the Nantes area].

More than 30 years after the legalization of contraception in France (Neuwirth law) it was interesting to access the sexual behavior and the practice of contraception of French female teenagers. It is with this purpose that this survey has been done in the city of Nantes in Loire Atlantique. 467 female teenagers, 13 to 21 years old, were concerned. Results point out that more of 75% of young girls who replied to this survey used one contraceptive method during the first sexual intercourse and condom is predominantly used. A few ambivalences stake out this life period, so preventive strategies have to be very specific in order to fight sexual transmitted diseases (STD) and AIDS.

Adolescent↗

Vasectomy, cigarette smoking, and age at first sexual intercourse as risk factors for prostate cancer in middle-aged men.

A population-based case-control study was conducted in men aged 60 or less to assess the risk of prostate cancer associated with vasectomy and other factors. Data were obtained from 216 case-control pairs by telephone interviews; this number represented 55% of all eligible cases. The matched pairs relative risk (RR) for vasectomy in ever married men was 1.4 with a 95% confidence interval (CI) of 0.9-2.3. There was a positive association between the number of years since vasectomy and prostate cancer risk (1-sided P = 0.01). Early age at first sexual intercourse was associated with increased prostate cancer risk (age less than 17 vs. 21+, RR = 2.3, 95% CI = 1.3, 4.0) but there were no consistent associations with number of sexual partners or frequency of sexual intercourse. Cigarette smoking was also associated with increased risk of prostate cancer (RR = 1.9, 95% CI = 1.2, 3.0) and there was a positive dose-response relationship with years of smoking (1-sided P = 0.001). We discuss the possible implication of the low response rate on each of these findings. To determine whether the association with vasectomy might have a hormonal basis, we compared levels of testosterone (T) and testosterone binding globulin-binding capacity (TeBG-bc) in 33 of the vasectomized control men with levels in 33 non-vasectomized controls of the same age, weight and height. T levels were higher in vasectomized than in non-vasectomized controls (1-sided P = 0.06). The ratio of T to TeBG-bc (an index of bioavailable T) was 13.5% higher in vasectomized men (1-sided P = 0.03).

Adenocarcinoma↗

Psychosocial predictors of delay of first sexual intercourse by adolescents.

This investigation predicted adolescents' delay of intercourse onset from attitudes, social norms, and self-efficacy about refraining from sexual intercourse. Age, gender, ethnicity, and parental education were also examined as predictors and moderators of the relationships among the 3 psychosocial determinants and onset. The participants (N = 827), part of a cohort initially surveyed in the 9th grade, reported at baseline that they had never engaged in intercourse. The multivariable proportional hazards regression model suggested that adolescents with more positive attitudinal and normative beliefs, as well as those with a parent who graduated from college, were less likely to engage in intercourse in the follow-up period (up to approximately 2 years). Interventions that include an objective to delay onset may benefit from addressing psychosocial determinants, especially attitudes and norms about sexual intercourse.

Adolescent↗

The HIV epidemic and changes in the use of contraception among Norwegian adolescents.

In order to describe the use of contraception and changes due to HIV/AIDS, a population-based survey of 3000 Norwegian adolescents aged 17-19 years old was conducted, with a response rate of 60.9%. At first intercourse, 29.2% of the girls and 33.3% of the boys reported using no contraception, while 44.4% of the girls and 39.7% of the boys reported using a condom. We observed an increase in the use of condoms in the years 1985-1988, which was reflected by 34.4% of the 19-year-olds having used a condom at their first intercourse, compared with 43.3 and 47.5% among the 18- and 17-year-olds, respectively. A logistic model showed that non-use of contraception was particularly associated with a low age at first experience of intercourse and consumption of alcohol immediately beforehand, while an increase in age at first intercourse and not having consumed alcohol before that occasion increased the likelihood of condom use.

Adolescent↗

Influence of circumcision and sexual behaviour on PSA levels in patients attending a sexually transmitted disease (STD) clinic.

Early age at first intercourse, increased number of sexual partners, lack of circumcision and history of sexually transmitted diseases (STDs) are associated with prostate cancer. There has been no investigation of the effect of these factors on prostate health at an early age. Previously collected serum samples from STD clinic attendees were tested retrospectively for anti-chlamydial antibodies, and prostate specific antigen (PSA) concentration. Patients at an STD clinic were interviewed regarding age of first intercourse, number of sexual partners and circumcision status. This was compared to clinical diagnosis, anti-chlamydial antibody titre and PSA concentration. The results showed: (1) that of patients with an anti-chlamydial antibody titre equal or greater than 1 in 64 (n=27) 37% had a PSA concentration greater than 0.8 ng/ml while those with a titre less than 1/64 (n=201) only 17% had a PSA >0.8 (P<0.05). (2) No association was found with circumcision status. (3) Early age of first intercourse and more than 20 sexual partners were associated with a synergistic increase in mean anti-chlamydial antibody titre and a mean PSA concentration of 1.2 ng/ml (95% CI 0.56-1.76). It is concluded that these results provide the first evidence that sexual behaviour related risk factors for prostate cancer do damage the prostate at an early age. Though they do not prove that infection is a cause of prostate cancer they do justify further research into the specificity of agents involved and impact of antibiotic treatment.Prostate Cancer and Prostatic Diseases (2001) 4, 228-231

Journal Article↗

Burning wood in the kitchen increases the risk of cervical neoplasia in HPV-infected women in Honduras.

There is suggestive evidence that the use of wood for cooking increases the risk of invasive cervical cancer. We investigated this association in women with cervical neoplasia in Honduras. Women aged 20-64 years with cervical intraepithelial neoplasia (CIN) grade I (n = 44), CIN II (n = 36) or CIN III (n = 45) were recruited from screening programs in Tegucigalpa City and each was matched by age and clinic to 2 controls (241 total) without cervical abnormalities. The clinics selected women of low socioeconomic status. Cervical scrapes were tested for the presence of human papillomavirus (HPV) DNA using a general primer set directed against the L1 open reading frame, and HPV genotyping was performed. Odds ratios (ORs) were computed through conditional logistic regression; p-values were from tests for linear trend of risk with increasing exposure. HPV DNA was detected in 48% of women with CIN I, 67% with CIN II and 89% with CIN III. The ORs were 1.5, 2.5 and 38.3 respectively. At univariate analysis, age at first intercourse was consistently lower among cases than controls. Risk was reduced by 50% or more in all 3 CIN classes when initiation of sexual activity at age 20 years or older was compared with initiation before age 16 years (p = 0.013 for CIN I). No effect was observed for smoking, oral contraceptives or previous cytologic screening. Effects for number of sexual partners, parity, age at first pregnancy and education were in the expected directions but never persisted after adjustment for HPV. Chronic exposure to wood smoke significantly increased the risk of CIN III (p = 0.022). However, women who said "No" when asked if they ever used wood in the kitchen had a higher risk than those with low or intermediate exposure. This was taken as evidence that the initial screening question had either been misunderstood or that answers were biased. Restricting the analysis to women who reported exposure yielded positive associations in all CIN classes with for CIN III ORs of 2.3 for 25-34 and 9.5 for 35+ years compared with women who had 1-14 years of exposure (p = 0.017). A multivariate analysis of the complete dataset (n = 366) allowed for separate ORs for HPV in each CIN class. Inclusion of age at first intercourse significantly improved this model (p = 0.021). Adding exposure to wood smoke further improved the model only if an interaction between woodsmoke and HPV was allowed for. If, as the data suggest, it was assumed that wood smoke had its effect among HPV-positives only, there was a significant linear dose-response relationship between exposure to woodsmoke and risk of CIN (p = 0.026). This association was independent of other risk factors including education, parity and number of sexual partners. ORs in the final model were 0.37 for age at first intercourse 20 years or higher and 5.69 for more than 35 years of exposure to wood burning in the kitchen. The present study suggests that the use of wood for cooking is a risk factor for cervical neoplasia that deserves further study, given its high prevalence in developing countries.

Adolescent↗

Do perceptions of friends' behaviors affect age at first sex? Evidence from Cebu, Philippines.

PURPOSE: To explore the effect of perceptions of friends' romantic and physical behaviors on adolescent sexual behavior and the relative influence of friends' sexual behaviors and maternal attitudes on age at first sex. METHODS: Using longitudinal data collected from 1943 adolescents who have never had sex at baseline in Cebu, Philippines, logistic regression assessed whether adolescents' perceptions of friends' sexual behaviors, measured at ages 14 to 16 years, were associated with age at first intercourse. Survival analysis assessed the hazard of having first intercourse by ages 17 to 19 years. Final models adjusted for sociodemographics, mothers'/caretakers' disapproval of premarital sex, living with a caretaker, and the adolescents' own behaviors at baseline. RESULTS: Boys and girls, who at ages 14 to 16 years, perceived that their friends had ever had boyfriends/girlfriends, dated, held hands, kissed, petted or had sex were significantly more likely to have experienced that behavior by ages 17 to 19 years. For each additional behavior an adolescent perceived his or her friends to have experienced, the hazard of having sex at a younger age increased by 1.15 (p = .02) among boys and 1.19 (p < .002) among girls, after adjusting for mothers'/caretakers' disapproval of premarital sex and other factors. CONCLUSIONS: These results demonstrate the important role of peers in light of competing influences in adolescents' lives. They provide support for asking at early ages what romantic and physical behaviors adolescents think their friends have experienced. Interventions can use such information to better prepare adolescents to make responsible and informed decisions about sexuality.

Adolescent↗

A rose by any other name? Objective knowledge, perceived knowledge, and adolescent male condom use.

OBJECTIVE: To investigate the role of objective and perceived knowledge about condoms in adolescent males' condom use at first intercourse. METHODS: A longitudinal analysis was conducted of data from a nationally representative sample of 404 virgin male adolescents who were aged 15 to 17 years at wave 1 and reported becoming sexually experienced at the second wave of data collection. Objective knowledge was measured as a 5-item knowledge test about condoms. Perceived knowledge was measured as a 5-item scale regarding participants' confidence about their answers on the objective knowledge test. Condom use was assessed by self-report. RESULTS: Objective and perceived knowledge were moderately correlated with each other. Male adolescents with low objective but high perceived knowledge were identified as being at particular risk for not using a condom in that they were nearly 3 times less likely to report using a condom at first intercourse (odds ratio: 0.35) than those with other levels of objective and perceived knowledge. CONCLUSIONS: Previous evidence suggests that knowledge about sex does not accurately predict sexual behavior. This lack of predictive accuracy may be because studies have focused only on objective knowledge. Our results suggest that both objective and perceived knowledge serve as antecedents to male condom use at first intercourse. However, those with higher perceived knowledge, particularly in the context of low objective knowledge, may be at greater risk for not using condoms. Addressing not only objective but also perceived knowledge may increase the effectiveness of interventions that are designed to increase rates of condom use among male adolescents.

Adolescent↗

Depot medroxyprogesterone acetate use in inner-city, minority adolescents: continuation rates and characteristics of long-term users.

OBJECTIVE: To identify continuation rates of depot medroxyprogesterone acetate (Depo-Provera) and characteristics of long-term users in a population of inner-city, minority adolescents with high pregnancy rates. DESIGN: Retrospective medical record review. SETTING: An inner-city adolescent clinic and an adolescent pregnancy program. METHODS: A review of the medical records of 250 females aged 13 to 20 years (mean +/- SD, 16.8 +/- 1.1 years), 62.9% Hispanic and 34.2% African American, receiving a first depot medroxyprogesterone acetate injection for contraception between August 1993 and June 1996 was conducted using a standardized form. The mean +/- SD age at menarche of the subjects was 11.6 +/- 1.4 years, and the mean +/- SD age at first intercourse was 14.1 +/- 1.3 years; the mean number of lifetime sex partners was 2.4. Of the subjects, 73.6% had used condoms, 32.0% used oral contraceptives, and none used implants. Of the 201 subjects for whom there were data in the medical records regarding prior fertility, 172 (85.6%) had been pregnant, and 145 (72.1%) had a child. Life table analysis was used to measure depot medroxyprogesterone acetate continuation rates and to compare subgroups of adolescents. RESULTS: Depot medroxyprogesterone acetate continuation rates were found to be 70.3% at 6 months, 48.3% at 9 months, 31.5% at 12 months, and 12.8% at 24 months. The most common reason for depot medroxyprogesterone acetate discontinuation was missed appointments (41.7%). Subjects were followed up for a mean +/- SD of 1.3 +/- 0.7 years after discontinuation of depot medroxyprogesterone acetate use; 46.7% became pregnant. Among those 156 adolescents who discontinued depotmedroxyprogesterone acetate use, 40.0% restarted the method at some later time. Continuation of depot medroxyprogesterone acetate use was more likely if age at first intercourse was younger than 13 years (P = .04). Continuation rates were not related to age, ethnicity, age at menarche, number of sex partners, use of other contraceptives, prior pregnancy, or having a child. CONCLUSIONS: In this study, just less than one third of the adolescents continued depot medroxyprogesterone acetate use for 1 year or longer. This suggests that depot medroxyprogesterone acetate does not function as a long-term method for most inner-city adolescents. The only characteristic that was associated with successful continuation of depot medroxyprogesterone acetate use was young age at first intercourse, implying that experience may be the main determinant of continuation.

Adolescent↗