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At least 127 records · Page 7Linked to original sources
PubMed1990

[Morphological study on growth process of primary dentition having distal step of the terminal plane. 2. Individual growth].

In order to analyze individual growth, 10 cases which contained longitudinal data and materials were chosen out of the 32 cases with bilateral distal step that were used in the study of Part I. The control group comprised the same twelve cases that were used in Part I. Observations of plaster models were made on the eruption age and eruption sequence of the first maxillary and mandibular permanent molars and incisors, the mesiodistal crown diameter, the interdental spaces in the primary dentition, and individual growth of the maxillary intercanine width. Cephalometric analysis was made on linear and angular items in which a significant difference between the two groups was found in the study Part I: Growth on the Average. Growth patterns were classified according to profilograms. The relationship between the terminal planes and analyzed items was also discussed. The results were as follows: 1. Individual growth data obtained from plaster models 1) Concerning the eruption age of the permanent teeth, the first maxillary molars of the examined group erupted in 5.84 years on the average. In cases of the control group, 6.42 years was the average. There was a significant difference between the two groups. The maxillary and mandibular central incisors of the examined group tended to erupt slightly earlier than the control group. 2) Concerning the eruption sequence of the permanent teeth, the first maxillary molars or the mandibular central incisors erupted earliest in the examined group, and the first mandibular molars or the mandibular central incisors in the control group. 2. Individual growth data obtained from cephalometrics 1) Concerning skeletal patterns, the examined group showed a significantly larger increase of the lower facial height (NF-Me) than the control group in the period from eruption of the first molars to eruption of the maxillary central incisors. In this period, 8 out of 10 cases of the examined group and 3 out of 12 cases of the control group showed the maximal growth change. 2) Concerning denture patterns, the maxillary incisor height (Ul-NF) increased markedly in the period from eruption of the first molars to eruption of the maxillary central incisors. This was found in 8 cases of the examined group and 4 cases of the control group.(ABSTRACT TRUNCATED AT 400 WORDS)

Cephalometry↗
PubMed1990

A longitudinal study comparing growth in diabetic pregnancies with growth in normal gestations: I. The fetal weight.

Diabetes mellitus is associated with fetal growth acceleration and retardation. These aberrations in fetal growth seem to be influenced by a variety of factors including vascular disease, glycemic control, hypertension and smoking. In order to characterize fetal growth under the above conditions, longitudinal sonographic evaluations were performed in 52 pregnant, insulin-dependent diabetic women with the usual monitoring of the patients' metabolic control. Regression analyses revealed that vascular disease and glycemic conditions were the most important influences for growth, with manifestation beyond the second trimester. With stringent glucose control (mean whole blood less than or equal to 100 mg/dl) in the absence of vasculopathy (white classes A, B, C), fetal growth was similar to that in normal pregnancies. In the presence of vasculopathy (white classes D and FR), growth was reduced, especially when near-normal glycemic levels were achieved. Conversely, in poorly controlled diabetic women, enhanced fetal growth were observed in patients with and without vasculopathy. No aberrations in fetal growth were observed, however, before the third trimester. The findings of our study demonstrate that vasculopathy and glycemia are dominant and independent regulators of fetal growth. However, their influences are not manifested in growth changes before the third trimester.

Embryonic and Fetal Development↗
PubMed1990

[The early development of Jacobson's organ in the nasal cavity of the rat before the inception of the secondary palatal development].

The early development of Jacobson's organ was studied by means of a series of embryos of the rat which were of various ages and exactly dated. Already at the youngest stage of those rats, the nasal cavity is just an open groove, the organ is a thickened epithelial layer at the medial nasal process. Only 15 h later, while the nasal grooves start to close from caudal to rostral, Jacobson's organ has acquired the shape of a deep, long cleft, situated within the broad nasal opening. On the 13th d of fetal life, a complete, caudally closed nasal cavity appears. By the means of fundamental growth changes, the already well developed organ has become shifted to a more caudal position and lies now above the primary palate. A shorter caudal part of the still cleft-like organ just starts to close itself thus forming its typical tube-like structure. Moreover strong nerve bundles running from Jacobson's organ to the brain indicate that in the meantime a sensory epithelium can be distinguished. Up to the 15th d of development, the tube-forming process of Jacobson's organ is completed. Parallel to this procedure, the surrounding nasal cavity acquires a caudal apertura nasalis interna by the rupture of the membrana bucconasalis while Jacobson's organ still lies above the rostral primary palate. Primary in the medial, somewhat later in the lateral part of the nasal cavity, first outlines of cartilage appear, visible as dense cell formations. Together with this, the paraseptal cartilage, in these stages closely connected to the septal cartilage, develops quite early. Between the 14th and 15th d of its fetal life, the flat, tube-formed Jacobson's organ of the rat gets turned from a primary horizontal into a vertical position, which brings its sensory epithelium to the medial side. It is assumed that this happens for functional reasons. Because of the obviously early and progressive development of Jacobson's organ within that of the nasal cavity, it seems to be probable that already the origin of the nose, the olfactory placodes, are determined in the directions both of the nasal cavity and of Jacobson's organ. Furthermore the results demonstrate an early preferential development of Jacobson's organ in comparison to that of the surrounding nasal cavity.

Animals↗
PubMed1989

[A comparative study on the structure and growth of the dentoskeleton and soft-tissue in normal occlusion].

A study of hard tissue and soft tissue contour and growth on normal occlusion among Chinese population was made by means of computerized radiographic cephalometrics. Correlation analysis and polygon methods were applied to analyse the profile contour. The result showed that the dento-skeletal pattern and integumental contour were not necessarily alike, the diversity could be quite prominent. As to the growth change features in soft-tissue and hard-tissue structure, we found that the growth behavior of the lips seemed to show a tendency to follow the dental structure directly. The bony profile tended to become less convex with aging, while the soft-tissue profile remained stable in its degree of convexity.

Adolescent↗
PubMedDate not supplied

[Kinetics of growth and development of Mycobacterium rubrum under conditions of periodic culturing].

The kinetics of growth, development, carotenogenesis and changes in the composition of the reaction medium were studied in the course of Mycobacterium rubrum batch cultivation in synthetic and complex media. The culture growth was found to be composed of five phases in the synthetic medium and of four phases in the complex medium. When the culture was grown in the synthetic medium, the phenomenon of distinct diauxy was recorded by changes in the specific growth rate as well as the economic and metabolic coefficients. These growth changes were shown to be associated with the fact that the culture started to assimilate sucrose instead of glucose at the subsequent growth phases, and carbotenogenesis was found to be uncoupled with the period of active biomass and protein synthesis.

Carotenoids↗
PubMed1989

[Position changes of mandibular condyle in Herbst treatment. Radiographic study].

The study aimed to analyse the short- und long-term changes in condyle position in Class II/1 malocclusions treated with the Herbst appliance. Cephalometric reoentgenograms from a Herbst group (n = 30, mean age 12.1 years) were compared to those of a Control group (n = 12, mean age 11.0 years). The total observation period was 3 1/2 years. Centric occlusion and mouth open profile roentgenograms (to visualize the condyle) were analysed at four occasions. Mandibular tracings from the mouth open headfilms were superimposed on the centric occlusion headfilms using the Nasion-Sella-Line (NSL) for reference. NSL and its perpendicle NSLP through Sella (S) were used as a reference grid for linear measurements. When starting Herbst treatment the condyle was displaced 6 mm anteriorly and caudally. After 7 months of treatment the condyle was located 0.8 mm caudally to the pre-treatment position. No difference existed, however, between the Herbst and Control group. During the total observation period of 3 1/2 years the condyle in both examination groups moved caudally and posteriorly. This was thought to be a result of normal growth changes. It was concluded that Herbst treatment did not have an adverse effect on the position of the condyle.

Activator Appliances↗
PubMed1989

[A longitudinal study of craniofacial growth in five cases with surgically repaired unilateral complete cleft lip and palate].

The aim of this longitudinal study was to cephalometrically assess growth changes of the craniofacial system in five cases with completed unilateral cleft of lip and palate, aged 8-11 years. Two types of study were performed: a) superimposition of cephalometric tracings of the lateral skull radiographs in two growth stages; b) metric analysis of SNA, SNB, NSAr, SArGo, ArGoMe angles, as well as S-Go:N-Me percentages. On the basis of the results obtained from this study, it was found posterior growth rotation in 4 out of 5 cases, bimaxillary rethrognathism, and a decrease of the SNA and an increase of the SNB angles during the growth period investigated.

Cephalometry↗
PubMed1977

The role of the mandible in mouse palatal development revisited.

Growth changes associated with formation of the secondary palate were studied in H-Velaz mouse embryos by morphometric measurement of medial sagittal sections of the heads between days 13 and 15 of embryonic development. Horizontalization of the palatine processes depends primarily on the length of the mandible and is effected by a shift of palatine process material into the supralingual space. The administration of 7.5 mg cortisone acetate im to the female on day 12, of 0.5 mg 6-aminonicotinamide im on day 14, or amniocentesis on day 14 significantly retards growth of the embryo in general and of the mandible in particular without significantly affecting deflexion of the skull base. The different spatial conditions created by disproportion between deflexion of the base and the length of the mandible cause irregularities in the course of horizontalization which lead, as a rule, to cleft palate.

6-Aminonicotinamide↗
PubMed1989

[The effect of recombinant human tumor necrosis factor alpha on malignant tumors in vivo. Physiopathologic basis for clinical oncology].

Effects of Recombinant Human Tumor Necrosis Factor-alpha on Malignant Tumors in vivo/Pathophysiological fundamentals for clinical oncology. The impact of recombinant human tumor necrosis factor-alpha (rhTNF-alpha; 6.6.10(6) U/mg protein) on growth, metabolism and perfusion of isotransplanted rat tumors (DS-carcinosarcomas) was investigated. Tumor growth was stimulated at low TNF doses (1 and 10 micrograms/kg), and significantly retarded at higher TNF dose levels (0.1 and 1.0 mg/kg). Growth changes were paralleled by variations in perfusion and metabolism. A reduced tumor blood flow enhanced the efficacy of a subsequent heat treatment. From these results, important implications for the clinical use of rhTNF-alpha are obvious (e.g., possible growth stimulation, timing of a combination therapy with other tumor treatment modalities).

Animals↗
PubMed1989

[Longitudinal changes in amounts of maxillary growth].

The purpose of this study is to investigate postnatal developmental changes in the shape of the maxilla. Normal maxillary form at each development stage and amounts of growth were analyzed by longitudinally measuring 136 Indian skulls. Maxillary growth changes were assumed on the basis of mean values and growth rates of each region measured. Results 1) Vertical growth Vertical growth of the maxilla (N-Pr) at the fifth (permanent-dentition) stage approximately doubled growth in the first (pre-eruption) stage. The corpus of the maxilla and its alveolar process lay beneath the foramen infraorbit. Vertical growth in this region (m-Pr) increases rapidly during the period of eruption of deciduous and permanent teeth. In permanent dentition, the vertical dimensions of the upper (N-m) and lower (m-Pr) parts of the foramen infraorbit were almost the same. 2) Growth in width As the eyes grow, the upper face widens. Resulting development in the tensed zygomatic-maxillary suture at the inferior margin of the orbit expands the upper surface of maxilla. Maxillary width increased by approximately 1.8 times between the first and fifth stages.

Cephalometry↗
PubMed1978

[Modification of the tongue in the treatment of progenia].

The size, position and function of the tongue affect the surrounding jaw regions. In class III malocclusions where the tongue is involved, the treatment must be directed toward the correction of the function and the change in the oral volume proportions. These requirements are largely met by the functional prognathism appliance. Growth changes, increases in length of the upper dental arch, decreases in length of the lower dental arch and displacements of the mandible in a posterior direction were observed in the patients treated up to now.

Cephalometry↗
PubMed1989

Cartilage derived proteoglycans in body fluids of children. Inverse correlation with age.

We have previously shown synovial fluid (SF) proteoglycan concentrations to be sensitive markers of altered cartilage metabolism in arthritis. We determined the proteoglycan concentrations in sera and SF from 23 patients with juvenile chronic arthritis and in sera from 30 healthy children by a specific enzyme linked immunosorbent assay. In both groups of children, decreasing concentrations of proteoglycans were seen during growth. Changes were most marked at the age of 12-13. The serum levels were higher in the healthy children. Our results suggest an age related metabolic change of articular cartilage, resulting in diminished release of proteoglycans to SF and blood with growing age up to 20 years. Measurement of proteoglycans could be a useful tool for studying this process.

Adolescent↗
PubMed1986

Is chloride depletion an important contributing cause of death in infants with bronchopulmonary dysplasia?

A retrospective analysis of infants with bronchopulmonary dysplasia requiring prolonged hospitalization (greater than 100 days) was carried out to determine those factors associated with fatal outcome. Twenty-three infants made up the study population. Eleven infants died and 12 survived (survivors). No differences were noted between the groups regarding ventilator requirement, radiographic changes, and medication use (digoxin, aldactazide), except for furosemide which was used twice as frequently in the group of infants who died v the group of infants who survived (P less than .001). Differences noted between the groups included moderate hypochloremia (chloride less than 80 mEq/L) in all 11 infants who died v six of 12 survivors, severe hypochloremia (chloride less than 70 mEq/L) in the nine of 11 infants who died v two of 12 survivors, metabolic alkalosis (pH greater than 7.45) in nine of 11 infants who died v three of 12 survivors, hypertension (systolic BP greater than 113 mm Hg) in eight of 11 infants who died v one of 12 survivors, decrease in head growth in ten of the 11 infants who died v one of the 12 survivors; these differences were all significant (P less than .001). The metabolic alkalosis and head growth changes appear to be related to the hypochloremia. The data suggest that chloride deficiency may be an important contributing factor in the genesis of poor outcome in infants with bronchopulmonary dysplasia and that close attention to chloride supplementation might influence outcome.

Acid-Base Imbalance↗
PubMed1977

[Characteristics of the follicular epithelium in the fishes with demersal roe. Concerning the classification of unilaminate monomorphous follicular epithelium of the vertebrates].

Follicular epithelium of Hemichromis during the periods of small and slow oocyte growth changes from flattened prismatic into high prismatic; during the periods of fast oocyte growth, the follicular epithelial cells undergo secretory specialization. Secretion is of apocrine type and forms the second oocyte tunica. According to the literature data analyzed and the author's investigation, in the development of unilaminate monomorphous follicular epithelii, it should be distinguished: a) period of primary transformation with characteristic intensive proliferation of epithelial cells, their morphologic transformation, upward growth of epithelium and increase of its physiological activity; b) period of secondary transformation either at the expense of secondary follicular epithelial flattening, or by means of secretory specialization of its cells. It is suggested to name unilaminate monomorphous follicular epithelii in vertebrates according to their construction at the end of the primary and by the character of the secondary transformation. Thus, follicular epithelium of Hemichromis can be defined as highly prismatic with secondary specialization.

Animals↗
PubMedDate not supplied

[Characteristics of growth and changes in the ultrafine structure of bacteria in the course of continuous cultivation on media containing ethanol].

A large number of bacterial strains assimilating chemical ethanol has been isolated using an original technique. Active growth of strains belonging to the genera Pseudomonas and, particularly, Acinetobacter was registered on mineral media containing ethanol. A mathematical model was constructed select a strain of Acinetobacter calcoaceticus K-9 during its continuous cultivation on media containing ethanol. The model makes it possible to determine conditions for producing a present amount of the biomass, the percentage of its yield, and the produc;iveness as a function of the dilution rate, temperature, and the concentration of ethanol and phosphoric acid in the medium. The main characteristics of the growth process in the studied factor space were established. The optimum conditions were calculated for growth of the strain with respect to each of the criteria. Under various conditions of bacterial growth, changes in the morphology and ultra-fine structure of the cells correlated with their physiological activity. The volume of the cells increased with the rate of dilution of the medium: the process can be described by a saturation curve. The presence of mesosomal structures is typical of the cells growing at low flow rates.

Acinetobacter↗
PubMed1978

Establishment of epithelial cell lines following exposure of cultured tracheal epithelium to 12-O-tetradecanoyl-phorbol-13-acetate.

In vitro exposure of rat tracheal epithelium to the tumor-promoting agent 12-O-tetradecanoyl-phorbol-13-acetate results in a marked increase in growth capacity. The growth changes are manifested in an increased rate of cell division and growth in primary cultures and in the establishment of permanent epithelial cell lines. Such changes did not occur in control cultures. Fourteen of the cell lines have been inoculated into immunosuppressed recipients, and all are nontumorigenic.

Animals↗
PubMed1975

[Biosynthesis of penicillin and the biphasal development of a P. chrysogenum culture].

The two-phase pattern of penicillin biosynthesis was observed only under definite cultivation conditions. When the conditions of the culture growth changed, the productivity curve also changed. The most high productivity levels on the glucose medium and the medium with glucose and lactose were noted at the beginning and in the middle of the process respectively. Under more or less equal conditions the productivity remained at the same level.

Culture Media↗