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Results for “HEART VALVE PROSTHESIS”

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At least 127 records · Page 7Linked to original sources
PubMed1991

[Reoperations in patients with heart valve prosthesis].

The results of operations performed for the second time on 193 patients with heart valve prostheses are analysed. Prosthesis endocarditis and thrombosis of the prosthesis are the most severe complications of valve replacement. An effective scheme for the performance of repeated operations in these patients is suggested, which was developed at the Bakulev Institute of Cardiovascular Surgery, USSR AMS. The study makes it possible to conclude that the risk of such operations is fully justified.

Adolescent↗
PubMed1981

Effect of pentoxifylline on red cell flexibility in arterio-sclerotic patients and in patients with heart valve prosthesis.

Red cell flexibility (RCF) was studied in 40 patients with severe occlusive arterio-sclerotic disease of the lower extremities (Group I) and in 17 patients with aortic or mitral valve prosthesis (Group II). RCF was studied in terms of rigidity and fragility using a filtration method. Pentoxifylline, which according to our previous observations increases the flexibility of red cells in healthy subjects, also markedly improved RCF in Group I, particularly in terms of fragility. The pentoxifylline-induced increase in RCF was less marked in Group II; only the rigidity parameter was significantly decreased. Reid et al [11] reported decreased deformability of red cells in patients with intermittent claudication. Since then a few other studies have been published, in which decreased red cell flexibility (RCF) was observed in patients with diabetic vascular disease [1, 4, 9, 12] and cerebral arteriosclerosis [10]. The objective of this study was to compare RCF in patients with widespread arteriosclerosis and heart valve prosthesis, the latter condition inducing a 'pure' mechanical red cell injury. Both patient groups were also studied after the administration of pentoxifylline, a drug known to improve the flexibility of normal red cells--see [6].

Adult↗
PubMedDate not supplied

Clinical experience with the Björk-Shiley integral monostrut heart valve prosthesis in the aortic and mitral position.

From May 1982 to May 1985, 174 Björk-Shiley integral monostrut (BSIM) heart valve prostheses were implanted in 160 patients. Eighty-eight valves were placed in mitral and 86 in aortic position. There were 92 males and 78 females with a mean age of 54.1 years (140 patients were in NYHA class III or IV (87.5%]. Single valve replacement was performed in 116 (72%) patients, 30 (19%) underwent multiple valve procedures and in 14 (9%) valve replacement was combined with coronary artery bypass surgery. There were no intraoperative deaths. Six patients died within the first month after surgery. One hundred and fifty-two (98.7%) patients were followed for a total of 190 patient years (average 14.8 months per patient). There were 8 late deaths (4.2 per 100 patient-years), 5 of these were valve related. Valve related complications were observed in 9 patients (4.5 per 100 patient-years). The overall incidence of peripheral embolization was 2.6 per 100 patient years. At the time of the follow-up study 136 (94%) patients were in functional class I and II. Fourteen patients with isolated AVR and six with MVR underwent hemodynamic evaluation on an average of 12 and 10 months after surgery. The early results suggest that the BSIM prosthesis represents a promising alternative in heart valve replacement, because there were no mechanical failures, thromboembolic complications are rare and hemodynamic performance is good.

Adolescent↗
PubMedDate not supplied

[Objective and subjective evaluation of the rehabilitation of patients following heart valve prosthesis].

Some aspects of the character of life of 71 patients after prosthetics of the heart valves were studied in a complex according to a medico-psychological program. The functional condition improved as the result of the operation in most of them, but many neuro-psychic complaints, poor self-appraisal, and dissatisfaction due to many limitations remained. An unfavourable tendency in return to work was revealed, which corresponded to subjective appraisal of rehabilitation and not to functional restoration.

Adult↗
PubMed1994

[Pregnancy in patients with heart valve prosthesis. Retrospective study apropos of 40 pregnancies].

In order to be able to offer pregnant artificial heart valve patients a practical management approach enabling reduction of maternal and fetal risks, the authors evaluated 40 pregnancies in 24 women. Thirty one valves had been inserted prior to these pregnancies: 24 mechanical valves and 7 biological valves. Different types of anticoagulation regimens were used in 32 pregnancies, while 8 took place without the use of anticoagulants (biological valves in sinus rhythm). From a clinical standpoint, almost all these pregnancies brought to term took place without cardiac decompensation. They resulted in the birth of 26 live infants, including one premature. One child was born at term with a phocomelia-type malformation and two were stillborn. There were five therapeutic abortions and six spontaneous abortions. There were four cases of thromboses of the artificial valve, three of which occurred in patients on heparin (dose of 5,000 IU/12 h). Three massive thromboses required emergency valve replacement surgery. There were also three embolic accidents, including one which regressed totally in a few hours. Two hemorrhagic complications occurred with subcutaneous heparin during the post-partum period. In practice, we feel that: when a young woman wishing to become pregnant requires valve replacement, a biological device is preferable; oral anticoagulants are contra-indicated during the first three months of pregnancy; the dose of 5,000 IU/12 h of heparin is insufficient to prevent thrombo-embolic accidents; when a mechanical valve is already implanted, the sequential treatment protocol of subcutaneous heparin--oral anticoagulant--subcutaneous heparin, with an initial dose of heparin of 5,000 IU/12 h then adjusted on the basis of APTT, is the best choice.

Adult↗