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At least 127 records · Page 7Linked to original sources

Compensatory growth of adipose tissue after partial lipectomy: involvement of serum factors.

The regulation of body weight/fat was studied by investigating mechanisms for compensatory adipose tissue growth after removal of bilateral epididymal fat pads from male adult Wistar rats. Food intake during the first 4 weeks and energy expenditure on Days 8-10 postsurgery were not different between lipectomized and sham operated rats. During Days 29-31 post surgery, a small (2.4%) but significant (P < 0.05) increase in heat production per metabolic body size was detected in lipectomized as compared with sham operated rats. The carcass composition of lipectomized and sham operated rats was not significantly different 16 weeks after surgery. The compensatory growth was fat pad-specific: mesenteric, retroperitoneal, and inguinal fat pads, but not perirenal fat pads, were heavier in lipectomized rats than in sham operated rats as early as 4 weeks postsurgery. Examination of fat cell size distribution in the compensating pads indicated a shift toward larger cells in retroperitoneal fat, but not in inguinal fat of lipectomized as compared with sham operated rats. Serum from lipectomized rats, but not media conditioned by exposure to retroperitoneal fat pads from lipectomized rats, stimulated proliferation of preadipocytes in vitro more than that from sham operated rats. Thus, compensatory adipose tissue growth after lipectomy may be mediated, in part, by blood-borne factors that are derived from tissues other than adipose tissue.

Adipocytes↗

Fat embolism syndrome in a case of abdominal lipectomy with liposuction.

Fat embolism syndrome is reported in a patient who underwent abdominoplasty and suction lipectomy for body contouring. Within 48 hours after surgery, she experienced adult respiratory distress syndrome, secondary to fat embolism syndrome. This was proven on bronchoscopy by evidence of fat laden macrophages. Aggressive respiratory support over 12 days resulted in patient survival.

Embolism, Fat↗

Suction lipectomy.

Suction lipectomy is a very effective and safe method, if performed by an experienced plastic surgeon. The authors demonstrate using a group of 284 patients operated on at the University Clinic of Plastic Surgery in Prague between 1994-1998, indications, the method and complications.

Adult↗

Suction-assisted lipectomy for lipodystrophy syndromes attributed to HIV-protease inhibitor use.

The addition of HIV-protease inhibitors to the arsenal of therapies for the treatment of HIV infection has resulted in significant suppression of viral load such that HIV-positive individuals experience reduced morbidity and extended life expectancy. Recently, a number of syndromes have been described involving abnormal fat distribution that may be associated with prolonged HIV-protease inhibitor therapy. These syndromes include hypertrophy of the cervicodorsal fat pad ("buffalo hump"); a tendency toward increased central adiposity ("protease paunch"); adiposity in the submental, mandibular, and lateral cheek regions of the face; and hypertrophy of adipose tissue in the breast in women. A peripheral lipodystrophy, or fat-wasting, in the extremities and face (particularly the malar and nasolabial fold regions) has also been observed. As these patients live longer and healthier lives, many are beginning to seek surgical correction of the disfigurements. In this regard, we present a review of the literature regarding these recently described syndromes to familiarize plastic and reconstructive surgeons with the unique deformities encountered in this ever-increasing patient population. We also present our results with suction-assisted lipectomy for treatment of these deformities. Physical findings, pathogenesis, and surgical management are discussed.

Adult↗

Saving a brachiocephalic fistula using lipectomy.

Many studies have demonstrated that functioning AVFs provide better vascular access outcomes compared to prosthetic devices. In April 2004, the Centers for Medicare and Medicaid Services (CMS) launched a "safe vascular access through collaborative fistula first initiative" (CMS, 2004). This breakthrough proposal cites studies that show increased mortality in patients who do not dialyze with a fistula. Veins too deep for needle cannulation are usually free of scars from intravenous (IV) sticks and, thus, are excellent options for fistula creation. Lipectomy can remove barriers, such as vein depth and limb obesity, creating an opportunity to have a functioning fistula.

Aged↗

Abdominal lipectomy as an office procedure.

Because of the increasing cost of hospitalization, many plastic surgeons have tried to make cosmetic surgery more affordable by performing procedures in the office operating room under local anesthesia and sedation. Standard abdominal lipectomy has classically been considered a procedure to be carried out in the hospital under general anesthesia. Following is the author's technique for performing the procedure under local anesthesia in the office setting.

Abdomen↗

Suction mammaplasty: the use of suction lipectomy to reduce large breasts.

The use of suction lipectomy to reduce breast volume is described. The technique applies only to a very limited group of patients whose nipple-areola complexes are normally located and whose enlargement is primarily fibrofatty in nature. Suction mammaplasty can be used as a sole technique in congenital asymmetry or in post-reduction enlargement or asymmetry.

Breast↗

Serial suction lipectomy.

Serial suction lipectomy is a safe method whereby larger areas and larger amounts of subcutaneous fat can be removed in several subsequent steps to minimize transfusion, minimize hospitalization, and maximize the improved health and safety of our patients. Six weeks should elapse between major resections, and a maximum of 2000 cc can be removed at one time unless transfusion is available.

Adult↗

Plasma lidocaine levels during augmentation mammaplasty and suction-assisted lipectomy.

Many plastic surgical procedures are dependent on or aided by the use of local anesthetics. Drug toxicity, although uncommon, is the most feared complication of this technique. There are multiple factors that lead to varying drug levels. These include drug concentration, speed of injection, rate of degradation, total dosage, site of injection or application, rate of administration, and the adjunctive use of vasoconstrictors. This study evaluates the use of subcutaneously injected lidocaine in patients undergoing suction-assisted lipectomy and augmentation mammaplasty. Lidocaine in the concentration of 0.5% containing either 1:100,000 or 1:200,000 epinephrine was used in doses up to 500 mg. Serial lidocaine levels were then obtained up to 1 1/2 hours after injection utilizing two different assay techniques. Our findings demonstrate consistently nondectable serum lidocaine levels despite the use of doses in excess of recommended "safe" amounts. This suggests that under specific circumstances and with certain operative procedures, lidocaine dosing can be liberalized.

Adipose Tissue↗

[Basedow exophthalmos: lipectomy or orbital expansion?].

Graves' disease is due to mismatching of the orbit and its contents. Primary muscular hypertrophy is often accompanied increased intraorbital pressure due to obstruction of the venolymphatic drainage at the orbital apex. In moist cases, the fat undergoes minimal volumetric and structural changes. Among the numerous techniques proposed for orbital decompression the solution which allows the greatest orbitoperiosteal expansion while preserving the integrity of the orbital fat is valgus displacement of the malar bone combined with resection of the lateral wall and recession of the inferior and medial orbital walls. This technique, which can be adapted to the severity of each case, is performed via a infraciliary transpalpebral facial incision. It is easier to perform than via a coronal incision. It should be preferred to trans-sinus techniques which have a limited and dangerous action (considerable incidence of postoperative diplopia) and decompression lipectomy, which is difficult to perform, with a light risk and, furthermore, does not take into account the fundamental physiological role of the orbital fat nor the essentially muscular pathogenesis of exophthalmos.

Adult↗

Abdominoplasty: peri- and supra-umbilical lipectomy.

The historical evolution of abdominoplasty, from the first reference to this type of operation in 1880 up to today, is summarized. A description is given of the author's contribution to abdominal surgery through a peri- and supra-umbilical lipectomy, which produces a better final outcome with regard to the resultant depression in this region, conveying a more natural aspect. The losangular scar for constructing the umbilicus is also reported.

Abdomen↗

Surgical remodeling of the silhouette by aspiration lipolysis or selective lipectomy.

The author, a pioneer in originating the technique of suction lipectomy, discusses in detail the pathophysiology of the fat cell and fat metabolism. In addition, he describes the surgical means by which, since 1977, he has popularized this innovative new approach to the treatment of unsightly fat deposits in many sites in the body, including the thighs, buttocks, abdomen, hips, arms, ankles, breasts, and submental regions.

Adipose Tissue↗

Controversies in plastic surgery: suction-assisted lipectomy (SAL) and the hCG (human chorionic gonadotropin) protocol for obesity treatment.

The advent of SAL (suction-assisted lipectomy) has dramatically increased the number of obese patients coming to our consultation offices. Despite several articles suggesting a conservative approach to fat suction, some reports insinuate that SAL might be a useful tool for obesity treatment. This hypothesis is refuted by a vast body of evidence that concludes that the adipose tissue may regenerate in adult humans. Therefore, surgical procedures are not advised as the method of choice to manage the disease. On the other hand, the terms obesity and being overweight may not be interchangeable. Obesity may be a disease whereas being overweight is a sign of the disease. Consequently, proper preoperative selection of candidates for SAL becomes mandatory. The hCG (human chorionic gonadotropin) method for obesity treatment appears to be a complete program for the management of obesity. It contains pharmacologic, dietetic, and behavior modification aspects in a 40-day course of treatment. Some data suggest hCG to be lipolytic, thus explaining former clinical observations regarding body fat redistribution in treated patients. hCG commercial preparations contain beta-endorphin, an opioid peptide linked to mood behavior. This article speculates on the possible actions of the complex hCG beta-endorphin in the neuromodulation of mood and energy metabolism. The method comprises a behavior modification that helps in handling the patient better. There are some correlations between a current behavior modification program and the basic guidelines contained in the hCG protocol. Thus, the hCG method appears to be a reasonable alternative in the management of a long-standing, unsolved problem of human metabolism.

Adipose Tissue↗

Effects of fat mass reduction by dieting and by lipectomy on carbohydrate metabolism in obese patients.

The interrelation of enlarged body fat mass (BFM) with reduced carbohydrate tolerance and hyperinsulinemia was studied in obese subjects with chemical diabetes. These patients were subjected to lipectomy following weight loss induced by a low-calorie, low-carbohydrate diet. An improvement in glucose tolerance and in insulin sensitivity and a reduction in insulin release during OGTT was observed after a diet-induced BFM loss of 9.9 +/-1.2 kg. Subsequent surgical reduction of BFM by 6.0 +/- 0.5 kg had no further effect upon carbohydrate tolerance, insulin release or insulin sensitivity though a marked decrease in basal plasma FFA values was observed. These findings suggest that fat mass enlargement per se has no effect on blood glucose homeostasis after oral or i.v. loading. The improvement in carbohydrate tolerance and in insulin resistance usually observed following diet-induced loss of BFM seems to be due to the reduction in calorie and carbohydrate intake rather than to decrease of BFM.

Adipose Tissue↗

Post-mastectomy breast reconstruction using a direct flap from an abdominal lipectomy.

If a patient requires a breast reconstruction and at the same time is a candidate for an abdominal lipectomy, it is possible to combine the operation and carry out a breast reconstruction using a direct flap from the abdominal wall. The technique of this two-stage operation is described. In suitable cases one can produce a breast resembling the normal without any obvious scarring to detract from the result and without the complication of a silastic prosthesis.

Abdominal Muscles↗