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Results for “Marijuana Use”

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PubMed1999

The risks for late adolescence of early adolescent marijuana use.

OBJECTIVES: The purpose of this study was to assess the relation of early adolescent marijuana use to late adolescent problem behaviors, drug-related attitudes, drug problems, and sibling and peer problem behavior. METHODS: African American (n = 627) and Puerto Rican (n = 555) youths completed questionnaires in their classrooms initially and were individually interviewed 5 years later. Logistic regression analysis estimated increases in the risk of behaviors or attitudes in late adolescence associated with more frequent marijuana use in early adolescence. RESULTS: Early adolescent marijuana use increased the risk in late adolescence of not graduating from high school; delinquency; having multiple sexual partners; not always using condoms; perceiving drugs as not harmful; having problems with cigarettes, alcohol, and marijuana; and having more friends who exhibit deviant behavior. These relations were maintained with controls for age, sex, ethnicity, and, when available, earlier psychosocial measures. CONCLUSIONS: Early adolescent marijuana use is related to later adolescent problems that limit the acquisition of skills necessary for employment and heighten the risks of contracting HIV and abusing legal and illegal substances. Hence, assessments of and treatments for adolescent marijuana use need to be incorporated in clinical practice.

Adolescent↗

PubMed2003

Earlier marijuana use and later problem behavior in Colombian youths.

OBJECTIVE: The study examined the relationship between earlier adolescent marijuana use and later adolescent behavioral problems. METHOD: A community-based sample of Colombian adolescents was interviewed in 1995-1996 and 1997-1998. The time 2 (T(2)) sample consisted of 1,151 males and 1,075 females. The psychosocial measures assessed adolescent problem behavior, the peer and sibling social network, and ecological/environmental stress and cultural domains. Logistic regression analyses included controls on demographic and time 1 (T(1)) dependent measures. RESULTS: The findings suggest that T(1) adolescent marijuana use was associated with increased risks for T(2) adolescent difficulty at work or school, violent experiences, peer marijuana use, and sibling marijuana problems. CONCLUSIONS: This study provides important evidence in this cohort of the specific relationship between T(1) adolescent marijuana use and T(2) adolescent problem behavior in a society in which drug use, crime, violence, and low educational attainment are pervasive. Similar findings have been shown in previous research with U.S. adolescents. The findings suggest that early adolescent marijuana use is associated with an increase in problem behavior during later adolescence.

Adolescent↗

PubMed1976

Medical implications of marijuana use.

The effect of marijuana smoking was studied in 28 healthy young adult men who had previously smoked marijuana for approximately 5 years each. The subjects were hospitalized on a closed research ward for 31 days during which comprehensive psychological, physiological, and medical observations and tests were done. Physical examinations, neurological examinations, chest X-rays, electrocardiograms, and clinical laboratory tests were all within normal limits. Marijuana produced inconstant changes in pulse rate and blood pressure in these studies. Six subjects were found to have significant reduction in resting vital capacity during the baseline period of the study which were felt to be related to their prior marijuana smoking. In contradistinction to these findings, 12 of 15 subjects had statistically significant increases in peak expiratory flow rate immediately following marijuana smoking. Body temperature tended to be slightly reduced during marijuana use.

Adult↗

PubMed2003

Family transmission of marijuana use, abuse, and dependence.

OBJECTIVE: To examine the familial aggregation of marijuana use, abuse, and dependence. METHOD: Adolescents recruited from residential and day treatment programs for youths with conduct and substance problems, matched controls, and all available family members were interviewed with structured research instruments. A total of 2,546 individuals from 781 families were interviewed. Risk ratios of relatives of clinical cases were calculated, compared with controls, for marijuana use, abuse, or dependence. Spousal, parent-offspring, and sibling correlations and the proportion of variance attributable to parent-offspring transmission were estimated using structural equation modeling. RESULTS: For all three measures, the risk ratios were elevated in the family members of clinical probands, with estimates ranging from 1.5 to 3.3. Spousal correlations ranged from 0.33 to 0.70. Parent-offspring correlations ranged from 0.17 to 0.30. Sibling correlations ranged from 0.34 to 0.44. The proportion of variance attributable to factors transmitted from parents to children ranged between 25% and 44%. CONCLUSIONS: Familial aggregation of marijuana use, abuse, and dependence is present for all three measures. The results suggest significant parent-offspring transmission of risk, sibling environmental influences, and assortative mating for all three levels of marijuana use.

Adolescent↗

PubMed1998

High school athletes and marijuana use.

Identifying groups of young people that might be especially susceptible to marijuana use would aid in the design and implementation of drug policy programs. This article examines whether those who participated in high school athletics have a different pattern of marijuana use than comparable non-athletes. The results indicate that male athletes have a higher incidence of marijuana use than non-athletes. The same is not true for female athletes, who actually engage in less marijuana use than their non-athlete counterparts. However, female athletes are more likely than non-athletes to wait until their post-high school years to try the drug for the first time.

Adolescent↗

PubMed1989

Effects of marijuana use during pregnancy on newborn cry.

The effects of maternal marijuana use on the newborn cry were studied in Jamaica, where it was possible to rule out confounding factors such as the use of other substances and demographic variables that have clouded previous studies and where higher dosages may make the effects more visible. The acoustic characteristics of the cries of 20 infants of marijuana users and 20 controls were analyzed. The cries of the infants of marijuana users were shorter, had a higher percentage of dysphonation, a higher and more variable fundamental frequency, and a lower first formant than controls. There was also a dose response relation between the first formant and marijuana use. We suggest that heavy marijuana use affects the neurophysiological integrity of the infant.

Acoustics↗

PubMed2006

Age-period-cohort influences on trends in past year marijuana use in the US from the 1984, 1990, 1995 and 2000 National Alcohol Surveys.

BACKGROUND: Previous studies have described trends in marijuana use in the US and examined age-period-cohort (APC) effects finding increased lifetime use among cohorts born after 1945. However, no studies have utilized data on current consumption in multiple cross-sectional surveys to estimate these factors. METHODS: Age-period-cohort models including demographic factors are estimated using logistic regressions in four US National Alcohol Surveys (NAS) conducted between 1984 and 2000. Trends in past year marijuana use are also evaluated. RESULTS: Marijuana use declined over the study period from 10% to 7.2% of the population. Declines were mainly seen among men, resulting in a degree of gender convergence, particularly for those aged 18-25. Significant effects of age, period and cohort were found, with steep declines in use by age from the early 20s to the 40s. All male cohorts born after 1945 and female cohorts born between 1945 and 1960 showed elevated prevalence compared to earlier cohorts. CONCLUSIONS: Trend results from the NAS differ from those in other surveys and indicate decreased prevalence of past year marijuana use and gender convergence. APC results confirm past findings of age effects and cohort differences between those born before and after 1945. Marijuana use presents many measurement difficulties and future research to understand differences across surveys is needed.

Adult↗

PubMed1995

Alcohol and marijuana use in a community-based sample of persons with spinal cord injury.

The prevalence of self-reported alcohol and marijuana use, along with alcohol abuse as measured by the Short Michigan Alcoholism Screening Test, was assessed for a community-based sample (n = 123) of persons with spinal cord injury (SCI). Correlates of alcohol and marijuana use and alcohol abuse also were examined, including demographic variables, measures of impairment, disability, and handicap, SCI medical complications, and measures of subjective assessment such as health rating, health maintenance behaviors, depression, life satisfaction, perceived stress, pain, and social support. Prevalence of alcohol use (59%) and marijuana use (16%) in persons with SCI was less than that of comparison groups in the general population. However, prevalence of alcohol abuse (21%) exceeded that of general population studies. Participants who abused alcohol shared the following criteria: (1) perceived their overall health as worse than those who did not abuse alcohol; (2) were more depressed; and (3) experienced more stress in their lives than those who did not abuse alcohol. Participants who used marijuana were younger at the time of the study and were younger at injury. They were also more depressed and more stressed. The indications of alcohol abuse in one in five persons with SCI living in the community mandates that screening, treatment, and referrals be part of any rehabilitation treatment program.

Adult↗

PubMed1990

Prevalence of marijuana use during pregnancy. A pilot study.

We examined the prevalence of marijuana use in a group of pregnant women using a qualitative, rapid urine screen to detect marijuana metabolites. Between July 1, 1987, and Aug 15, 1987, 322 consecutive patients underwent an anonymous urine toxicology screen at the time of admission to the labor-and-delivery unit. Patients were identified only by a consecutive number and by their age, race, marital status, gravidity, parity and obstetric service (clinic vs. private). The prevalence of positive urine toxicologic screens for marijuana was 19.9% among the study population (64 positive tests among 322 women screened). The prevalence was greater among the clinic patients than the private patients (52 of 161, or 32.3%, vs. 12 of 161, or 7.5%, respectively). The distribution of race and marital status among the marijuana-positive and -negative groups were also significantly different. Specifically, the proportions of black and single women were higher among the marijuana-positive group. Our findings suggest that marijuana use is common in our obstetric patients. The possible association between marijuana use during pregnancy and perinatal morbidity, as well as the unreliable nature of patient drug histories, may support the use of rapid, inexpensive screening techniques, especially if general screening is considered.

Adult↗

PubMed2006

Marijuana motives: young adults' reasons for using marijuana.

Previous research has evaluated marijuana motives among adolescents and emerging adults using a predetermined set of motives, largely adapted from the alcohol literature. This research was designed to identify marijuana motives from the perspective of the user. Recent high school graduates who reported using marijuana (N=634) provided self-generated reasons for using. The most frequently reported reasons included enjoyment/fun, conformity, experimentation, social enhancement, boredom, and relaxation. Regression analyses revealed that experimentation was consistently associated with less use and fewer problems whereas enjoyment, habit, activity enhancement, and altered perception or perspectives were associated with heavier use and more problems.

Adult↗

PubMed2001

Temporal indication of marijuana use can be estimated from plasma and urine concentrations of delta9-tetrahydrocannabinol, 11-hydroxy-delta9-tetrahydrocannabinol, and 11-nor-delta9-tetrahydrocannabinol-9-carboxylic acid.

Current technology establishes marijuana use based upon detection of the pharmacologically inactive cannabinoid metabolite (11-nor-delta9-carboxy-tetrahydrocannabinol-9-carboxylic acid, THC-COOH) in urine. No accurate prediction of time of use is possible because THC-COOH has a half-life of 6 days. To determine if a temporal relationship between marijuana use and metabolite excretion patterns could be established, eight healthy user-volunteers (18-35 years old) smoked marijuana cigarettes containing 0% (placebo), 1.77%, and 3.58% delta9-tetrahydrocannabinol (THC). Plasma and urine were collected prior to smoking, 5 min after smoking, and hourly thereafter for 8 h for measurement of cannabinoid concentrations by gas chromatography-mass spectrometry. Mathematical models proposed for determination of recent marijuana use were applied to data from this study and verified the temporal use of marijuana. One subject, who later admitted chronic marijuana use (urine baseline THCCOOH, 529.2 ng/mL; plasma, 75.5 ng/mL), excreted 8beta-dihydroxy-THC, peaking 2 h postsmoking (92.3 ng/mL). Urinary THC, the psychoactive component of marijuana, concentrations peaked 2 h after smoking and declined to assay limit of detection (LOD) (1.5 ng/mL) by 6 h. 11-Hydroxy-delta9-tetrahydrocannabinol (11-OH-THC) and THCCOOH were detectable for the entire 8-h testing period but continued to decrease. Urinary concentrations of THC greater than 1.5 ng/mL suggests marijuana use during the previous 8-h time period.

Adolescent↗

PubMedDate not supplied

Occupational attainment, smoking, alcohol intake, and marijuana use: ethnic-gender differences in the CARDIA study.

OBJECTIVES: To evaluate the prospective interrelationship of smoking, alcohol intake, marijuana use, and educational and occupational attainment of Black and White young adults. METHODS: Logistic or mixed model linear regression were used to evaluate relationships between self-reported substance use, ethnicity, gender, college graduation, and four measures of occupational attainment. RESULTS: College graduation in the next 10 years was negatively associated with smoking and marijuana use, but not daily alcohol consumption in all ethnic and gender groups. In Whites, marijuana use was associated with less prestigious occupations and lower family income, while smoking was unrelated and moderate daily drinking was positively associated. In Blacks, marijuana use was generally unrelated to occupational measures, while smoking and daily alcohol consumption were negatively associated. CONCLUSIONS: Relationships between smoking, marijuana use, daily drinking, and occupational attainment were not universally negative in this age group. Substance use, particularly smoking, is associated with reduced occupational attainment in Blacks compared with Whites after considering sociodemographic factors potentially limiting educational progression and occupational attainment.

Achievement↗

PubMedDate not supplied

Father's influence on his daughter's marijuana use viewed in a mother and peer context.

A study of the fathers' impact on their daughters' marijuana use is presented viewed in the context of the mother and the daughters' peer group. Four hundred and three female college student volunteers and their fathers were administered closed-ended questionnaires which included a number of scales assessing various parental and peer characteristics. The results indicated that the domain (set) of paternal variables had a direct impact on daughters' marijuana use independent of the effects of the maternal domain. However, in the case of the peer group, the fathers' effects on daughters' marijuana use were not direct but were mediated through the peer domain. In addition, individual protective (nondrug-conducive) paternal variables served to mitigate the effects of certain maternal and peer risk (drug conductive) factors on the daughters' marijuana use. The findings underscore the importance of identifying those paternal factors that exert an influence on the daughters' marijuana use alone or in combination with other interpersonal (maternal, peer) factors.

Adolescent↗

PubMed2004

Marijuana use and risk of oral squamous cell carcinoma.

Previous laboratory investigations, case reports, and a hospital-based case-control study have suggested that marijuana use may be a risk factor for squamous cell head and neck cancer. We conducted a population-based case-control study to determine whether marijuana use is associated with the development of oral squamous cell carcinoma (OSCC). Case subjects (n = 407) were 18-65-year-old residents of three counties in western Washington State who were newly diagnosed with OSCC from 1985 through 1995. Control subjects (n = 615), who were similar to the cases with respect to age and sex, were selected from the general population using random-digit telephone dialing. Lifetime histories of marijuana use and exposure to known OSCC risk factors were ascertained using a structured questionnaire. Information on genetic polymorphisms in glutathione S-transferase enzymes was obtained from assays on participant DNA. Odds ratios for associations with features of marijuana use were adjusted for sex, education, birth year, alcohol consumption, and cigarette smoking. A similar proportion of case subjects (25.6%) and control subjects (24.4%) reported ever use of marijuana (adjusted odds ratio, 0.9; 95% confidence interval, 0.6-1.3). There were no trends in risk observed with increasing duration or average frequency of use or time since first or last use. No subgroup defined by known or suspected OSCC risk factors (age, cigarette smoking, alcohol consumption, and genetic polymorphisms) showed an increased risk. Marijuana use was not associated with OSCC risk in this large, population-based study.

Adolescent↗

PubMed2002

Factors associated with regular marijuana use among high school students: a long-term follow-up study.

The present study investigated whether several behavioral and psychosocial factors measured during early adolescence predicted regular marijuana use 6 years later in a sample of high school students. As part of a school-based survey. 7th-grade students (N = 1,132) reported levels of alcohol, tobacco, and marijuana use, and were assessed on several domains of psychosocial functioning potentially relevant in the etiology of marijuana use. When students were followed-up in the 12th-grade, 14% smoked marijuana on a regular basis (once or more per month). Findings indicated that early cigarette smoking, alcohol use, and alcohol intoxication predicted later regular marijuana use. For boys, early marijuana use increased the odds for later regular marijuana use. Cigarette smoking by friends and siblings during early adolescence also increased the likelihood of later monthly marijuana use. The findings suggest that early prevention programs for adolescent alcohol, tobacco, and/or other drug use may have important preventive effects in terms of potentially more serious levels of marijuana involvement later in adolescence and early adulthood.

Adolescent↗

PubMedDate not supplied

The relations of trait anxiety, anxiety sensitivity, and sensation seeking to adolescents' motivations for alcohol, cigarette, and marijuana use.

The present study investigated relations of anxiety sensitivity and other theoretically relevant personality factors to Copper's [Psychological Assessment 6 (1994) 117.] four categories of substance use motivations as applied to teens' use of alcohol, cigarettes, and marijuana. A sample of 508 adolescents (238 females, 270 males; mean age = 15.1 years) completed the Trait subscale of the State-Trait Anxiety Inventory for Children, the Childhood Anxiety Sensitivity Index (CASI), and the Intensity and Novelty subscales of the Arnett Inventory of Sensation Seeking. Users of each substance also completed the Drinking Motives Questionnaire-Revised (DMQ-R) and/or author-compiled measures for assessing motives for cigarette smoking and marijuana use, respectively. Multiple regression analyses revealed that, in the case of each drug, the block of personality variables predicted "risky" substance use motives (i.e., coping, enhancement, and/or conformity motives) over-and-above demographics. High intensity seeking and low anxiety sensitivity predicted enhancement motives for alcohol use, high anxiety sensitivity predicted conformity motives for alcohol and marijuana use, and high trait anxiety predicted coping motives for alcohol and cigarette use. Moreover, anxiety sensitivity moderated the relation between trait anxiety and coping motives for alcohol and cigarette use: the trait anxiety-coping motives relation was stronger for high, than for low, anxiety sensitive individuals. Implications of the findings for improving substance abuse prevention efforts for youth will be discussed.

Adolescent↗

PubMed1997

Memory activation and expectancy as prospective predictors of alcohol and marijuana use.

This study examined whether indicators of drug-related memory associations predicted drug use prospectively. The predictive effects of outcome expectancies, sensation seeking, and other variables also were investigated. The results revealed that the memory association measures significantly predicted subsequent drug use. Outcome expectancies and sensation seeking predicted alcohol use, but not marijuana use. The findings suggest 2 possibly different aspects of cognition involved in drug use motivation: (a) a memory activation or implicit cognition component, representing the effects of memory associations that are prompted relatively spontaneously by the prevailing motivational and situational circumstances and (b) an outcome expectancy component, which is more likely to reflect explicit cognitions involved in introspection and deliberate decision-making processes.

Adult↗

PubMed2004

Marijuana use and epilepsy: prevalence in patients of a tertiary care epilepsy center.

The authors sought to determine the prevalence of marijuana use in patients with epilepsy by performing a telephone survey in a tertiary care epilepsy center. Twenty-one percent of subjects had used marijuana in the past year with the majority of active users reporting beneficial effects on seizures. Twenty-four percent of all subjects believed marijuana was an effective therapy for epilepsy. Despite limited evidence of efficacy, many patients with epilepsy believe marijuana is an effective therapy for epilepsy and are actively using it.

Adult↗