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Results for “Neoplasms, Muscle Tissue”

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At least 127 records · Page 7Linked to original sources
PubMed1990

Elastosis in granular cell tumours: prevalence and distribution.

Elastosis, a previously unreported feature, was found to be common in granular cell tumours. Twenty-four of 28 consecutive granular cell tumours were shown to display elastosis. The elastosis was found in three main sites: adventitial, interstitial and septal. Elastosis is statistically associated with the fibrosis present within this tumour. It appears that elastic fibres are synthesized by connective tissue cells, possibly induced by the tumour cells.

Adolescent↗
PubMed2001

Recent progress in the classification of soft tissue tumors: role of genetics and clinical implications.

Soft tissue tumors comprise a vast and heterogeneous group of neoplasms. Because different tumors often have different biological behaviors and respond differently to various therapeutic modalities, precise classification is paramount. The majority of soft tissue tumors were first delineated on the basis of morphologic and clinical findings, which in many cases were adequate to accurately separate different tumors into homogeneous groups; however, it has increasingly been appreciated that many entities are actually heterogeneous groups of tumors that have similar histologic and pathologic characteristics but differ in their clinical behavior and underlying pathogenesis. Within the past several years, great strides have been made in the purification of different entities. This accomplishment has largely been because of advances in our understanding of the molecular genetics that underlie the pathogenesis of many sarcomas and the development of new and specific tumor markers. This review highlights some important recent work in two selected soft tissue tumors-gastrointestinal stromal tumor and inflammatory myofibroblastic tumor. These examples illustrate the type of progress that is being made in the classification of soft tissue tumors.

Biomarkers, Tumor↗
PubMedDate not supplied

Malignant smooth muscle tumors of the gastrointestinal tract: an ultrastructural study of 20 cases.

Twenty malignant soft tissue tumors arising from the stomach or intestine have been studied by light and electron microscopy, and the clinical records of each patient reviewed. The tumors were all considered to be of smooth muscle origin by light microscopy: Ten were spindle cell and ten were epitheloid neoplasms. By electron microscopy, only five tumors possessed smooth muscle features. A sequence of dedifferentiation could be traced among the remaining cases, indicating that the epitheloid tumors are of smooth muscle derivation. Awareness of the broad spectrum of fine structure displayed by these neoplasms will facilitate their ultrastructural identification.

Adult↗
PubMed1977

[Fine structure of the myoblastic myoma].

A series of 10 myoblastic myomas were examined with the light and electron microscope. Based on electron microscopical examinations, the findings permitted to divide the cases according to their most probable histogenesis in two groups as follows: a) the granular lesions of the appendix and those of the hypophyseal infundibulum most probably originate from nervous tissue; b) the lesions of the skin and the tongue most probably are results of alterations of cell metabolism.

Appendiceal Neoplasms↗
PubMed1987

Infiltrating orbital granular cell tumour: a case report and literature review.

A surgical biopsy of an infiltrative retrobulbar mass in a 44-year-old man was diagnosed as granular cell tumour. Electron microscopy and immunoperoxidase stains were used to confirm the diagnosis and to study the histogenesis of this rare soft tissue neoplasm. S-100 stain was positive, while neuron-specific enolase and myoglobin stains were negative, suggesting a non-specific neural origin for the cells. The capability of this tumour to invade surrounding tissues has seldom been described in the orbit and is demonstrated by this case.

Adult↗