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At least 127 records · Page 7Linked to original sources
PubMed2001

Oral manifestations of human immunodeficiency virus (HIV)-infected patients in Singapore.

INTRODUCTION: Oral lesions have been recognised as prominent features of acquired immune deficiency syndrome (AIDS) and human immunodeficiency virus (HIV) infection since the beginning of the epidemic. OBJECTIVE: This descriptive study was conducted to study the types of oral lesions among HIV-infected patients in Singapore. MATERIALS AND METHODS: Oral examination was done on 81 randomly selected HIV-infected patients attending the specialist outpatient clinic at the Communicable Disease Centre. RESULTS: A total of 9 different lesions were observed in 45 (56%) patients. The lesions observed were oral candidosis (35%), periodontal disease (16%), aphthous-like ulcers (5%), oral hairy leukoplakia (5%) and lymphoma (1%). CONCLUSION: The oral manifestations of HIV-infected patients in Singapore appear to be less frequent in comparison with those patients from Africa and Europe. Similarities in oral findings among the HIV-infected patients in Asia are evident with a notable lack of oral Kaposi's sarcoma (KS) and a low prevalence of non-Hodgkin's lymphoma and oral hairy leukoplakia.

Adult↗
PubMed1990

Oral manifestations of AIDS in a heterosexual population in a Zaire hospital.

Oral lesions associated with HIV infection as classified by the WHO Collaborative Centre for Oral manifestation of HIV were studied in 83 heterosexual AIDS patients in Kinshasa, Zaire. One or more lesions were fungal (94%), bacterial (33%) and viral (23%). Neoplasm was found in 12% of cases while lesions of unknown etiology in 14%. As location of those lesions, the palate, lips, tongue and the buccal mucosae mostly predominate as sites. The findings from this study were clinically similar to those reported in AIDS in other areas.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[Oral manifestations of acquired bullous dermatoses].

The authors suggest studying the principal oral manifestations of acquired bullous dermatosis, such as malignant pemphigus, bullous pemphigoid, cicatricial pemphigoid, bullous polymorphe erythema, pluri-orificial ectodermosis, Lyell's syndrome, bullous toxidermia, bullous lichen planus and porphyria. These diseases will be described for the following aspects: clinical manifestations, diagnosis, evolution and treatment.

Fluorescent Antibody Technique↗
PubMed1975

Oral manifestations of Morquio's syndrome.

The clinical and laboratory findings in two siblings affected with Morquio's syndrome are described. The oral findings, consisting of disturbances in the structure of the enamel in both deciduous and permanent teeth, resemble those of amelogenesis imperfecta, Type 1. Preformed crowns are recommended as the initial treatment, in order to avoid loss of vertical height. The dentist's familiarity with the oral manifestations of Morquio's disease may contribute to the early detection of this condition.

Child↗
PubMed1994

The diagnosis and treatment of discoid lupus erythematosus with oral manifestations only: a case report.

A case of discoid lupus erythematosus with oral manifestations only is presented. The patient complained of painful palatal ulcers that limited her dietary intake. A topical therapeutic regimen using plastic carriers containing clobetasol propionate was beneficial in significantly relieving the oral discomfort. The clinical and microscopic differential diagnoses for this mucocutaneous disease are also discussed.

Clobetasol↗
PubMed2006

Oral manifestations in HIV/AIDS infected patients from India.

OBJECTIVES: To assess types and prevalence of HIV-related oral lesions among HIV-infected individuals in south India and to correlate common oral findings with co-morbidities, gender, age and medication. SUBJECTS AND METHODS: One hundred and one patients with HIV infection or AIDS at infectious diseases units of Attavar Hospital, Mangalore, and medical wards of Kasturba Medical College, Manipal, were selected. Sociodemographic information was obtained using a structured questionnaire. Oral lesions were diagnosed according to the presumptive criteria of EEC-Clearinghouse Classification. Clinical history was retrieved from patient's medical records. RESULTS: Erythematous candidiasis (44.5%), melanotic hyperpigmentaion (34.6%) and xerostomia (29.7%) were among the most common oral manifestations. A significant association was found between oral candidiasis and advanced immunosuppression (P < 0.05). Oral hairy leukoplakia (OHL) was predominant in individuals <35 years (P < 0.05). Melanotic hyperpigmentation was significantly associated with highly active antiretroviral therapy (P < 0.05). OHL was more frequent in patients with HIV-associated tuberculosis. Linear gingival erythema was more predominant in females. CONCLUSIONS: Oral hairy leukoplakia showed a positive relationship with patients younger than 35 years. Oral candidiasis can act as a marker for immunosuppression. Angular cheilitis was predominant in the symptomatic stage.

Adolescent↗
PubMed1997

Oral manifestations of collagen vascular disease.

Lupus erythematosus is a multisystem disorder. One of its defining features is oral ulceration. In addition to oral ulcers, cheilitis may occur. Sjögren's syndrome is an autoimmune disorder of exocrine glands that causes a decrease in salivary gland function. This results in symptoms of xerostomia, which can be complicated by caries. Scleroderma has rare oral manifestations, which include a decrease in the maximal oral aperture and mat-like telangiectasias.

Autoimmune Diseases↗
PubMed1994

Median rhomboid glossitis. An oral manifestation in patients infected with HIV.

A follow-up study included the oral examination of 39 persons known to be infected with the human immunodeficiency virus. In addition to the other human immunodeficiency virus-associated oral lesions, lesions clinically similar to the smooth form of median rhomboid glossitis, which is now believed to be erythematous candidiasis located in the dorsum of the tongue, were found in seven patients (18%). Patients with median rhomboid glossitis were classified in different stages of the Centers for Disease Control 1986 classification system and showed an average of CD+4 cell counts 397.5/mm3. Also the presence or the absence of anti-p24 antibodies in the serum and stimulated whole saliva of the patients with median rhomboid glossitis did not correlate with the stage of the disease or with low levels of CD+4 cell counts as in other forms of oral candidiasis. Therefore our results suggest that median rhomboid glossitis should be included as a distinct form of oral candidiasis in the classification of the oral manifestations of infection with the human immunodeficiency virus.

AIDS-Related Opportunistic Infections↗
PubMed1995

Oral manifestations of diabetes mellitus in controlled and uncontrolled patients.

The authors studied the oral manifestations of a sample of 70 diabetic patients, divided into controlled and uncontrolled patients. Medical history and stomatological data were analyzed and diabetic controlled patients were matched to uncontrolled patients. The main symptoms observed were hyposalivation, taste alterations and burning mouth, with the main sign being parotid enlargement. The lesions observed were candidosis of the erythematous type and proliferative lesions both associated to the use of total prosthesis. No pathognomic lesions or alterations could be observed in relation to the disease. The frequency of carriers of Candida albicans and also the lesions observed could be compared to normal patients also using total dentures.

Candidiasis, Oral↗
PubMed1988

Oral manifestations of agranulocytosis associated with methimazole therapy.

This paper reports a case of agranulocytosis that developed in a patient with hyperthyroidism two months after the administration of methimazole. The patient manifested symptoms of fever, sore throat, profound leukopenia, and oral complications such as generalized gingival necrosis and mucosa ulceration, which subsequently abated upon withdrawal of the drug. Dental practitioners should be aware of the potential of agranulocytosis associated with methimazole therapy. The oral manifestations should be kept in mind.

Adult↗
PubMedDate not supplied

Oral manifestations of Crohn disease: update of the literature and report of case.

Crohn disease, a devastating chronic illness, often develops in the childhood years. The disease is a segmental transmural intestinal disease that may involve one or more segments of the gut from the mouth to the anus. Crohn disease is frequently confused with ulcerative colitis. Frequent oral manifestations include persistent oral ulcerations, diffuse gingival swelling, mucosal hyperplasia and fissuring, cheilitis, and pyostomatitis vegetans. Frequently, oral biopsy is essential in establishing a correct diagnosis of the disease. Although no cure is currently available for the Crohn disease, the proper diagnosis of the problem is essential for providing symptomatic relief. A case report is presented documenting the value of the proper diagnosis of the disease. The literature is reviewed and updated.

Child↗
PubMed1991

Oral manifestations of HIV infection.

Oral lesions are frequently seen in association with all stages of infection with the human immunodeficiency virus (HIV). Many of these lesions occur as the first clinical sign of HIV infection. These lesions include candidiasis, hairy leukoplakia, warts, ulcers, and an aggressive form of periodontal disease. Careful oral examination may reveal lesions that alter Centers for Disease Control staging.

Acquired Immunodeficiency Syndrome↗
PubMed1991

[The oral manifestations during Kaposi's disease].

Kaposi's sarcoma is a rare neoplastic disease of the vascular system with multiple foci. Oral manifestations are uncommon. The authors report an oral localization of a Kaposi's disease; the etiopathogenesis, the clinical features and the treatment of such lesions are discussed.

Aged↗
PubMedDate not supplied

Oral manifestations of HIV disease.

Oral disease is frequently associated with HIV. While nearly all oral disorders associated with HIV infection also occur in other conditions characterized by immunosuppression, no other condition is associated with as wide and significant a spectrum of oral disease as is HIV infection. Many HIV-associated oral disorders occur early in HIV infection, not infrequently as the presenting sign or symptom. Thus, early detection of associated oral disease should, in many cases, result in earlier diagnosis of HIV infection. Likewise, awareness of the variety of oral disorders which can develop throughout the course of HIV infection, and coordination of health care services between physician and dentist, should improve overall health and comfort of the patient. This paper reviews the clinical, diagnostic and therapeutic aspects of HIV-associated oral disorders.

Bacterial Infections↗
PubMed1994

Oral manifestations associated with HIV-related disease as markers for immune suppression and AIDS.

BACKGROUND: Oral lesions are common findings in HIV-related disease, but little is known about their significance in predicting immune suppression among a representative group of HIV-infected persons. METHODS: Oral examinations were performed on 454 patients who came to an outpatient dental clinic for dental care. CD4+ cell counts were obtained within 2 months of the examination. RESULTS: In persons with a specific lesion and a CD4+ cell count below 200 cells/mm3 the corresponding mean CD4+ cell counts and predictive values were 149.5 cells/mm3 and 69.9% for candidiasis, 143.3 cells/mm3 and 70.1% for oral hairy leukoplakia, 126.0 cells/mm3 and 69.4% for xerostomia, 51.8 cells/mm3 and 95.1% for necrotizing ulcerative periodontitis, 98.7 cells/mm3 and 87.0% for long-standing herpes simplex virus infections, 66.6 cells/mm3 and 93.6% for Kaposi's sarcoma, and 33.7 cells/mm3 and 100% for major aphthous ulcers. The mean CD4+ cell count declined with increased numbers of different concurrent lesions. CONCLUSION: The presence of specific oral manifestations and the number of different concurrent intraoral lesions among HIV-infected persons are associated with severe immune suppression and AIDS. Oral examinations are an essential component for early recognition of disease progression and comprehensive evaluation of HIV-infected patients.

Acquired Immunodeficiency Syndrome↗