Neonatal cardiology casebook. Emergency pulmonary balloon valvuloplasty of congenital pulmonary valve stenosis.
Explore the source record for details and available documents.
SEARCH · PubMed Health
Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
To assess right ventricular (RV) diastolic filling in children with pulmonary stenosis (PS), 14 patients (mean age 5.1 years) were examined immediately before and after pulmonary balloon valvuloplasty. Fourteen normal children (mean age 4.8 years) were also studied. From the tricuspid valve inflow Doppler study, the following measurements were made at peak inspiration: peak velocities at rapid filling (peak E) and during atrial contraction (peak A), ratio of peak E to peak A velocities, RV peak filling rate normalized for stroke volume, total area under the Doppler curve, percent of the total Doppler area occurring in the first third of diastole (0.33 area fraction), percent of the total area occurring under the E wave (E area fraction), percent of the total area occurring under the A wave (A area fraction) and the ratio of E area to A area. Before balloon valvuloplasty, the patients with PS had higher peak A velocity (0.64 +/- 0.28 vs 0.39 +/- 0.08 m/s), lower E/A velocity ratio (1.11 +/- 0.52 vs 1.76 +/- 0.45), lower 0.33 area fraction (0.34 +/- 0.14 vs 0.49 +/- 0.08), higher A area fraction (0.45 +/- 0.21 vs 0.27 +/- 0.09) and lower E/A area ratio (1.73 +/- 1.05 vs 2.96 +/- 1.14) than the normal subjects (p less than 0.01). In patients before and after balloon valvuloplasty, there was a significant difference in RV outflow gradient (71 +/- 35 vs 28 +/- 15 mm Hg), but there was no change in any Doppler index. Thus, patients with PS have abnormal diastolic filling with decreased filling in early diastole and increased filling during atrial contraction.(ABSTRACT TRUNCATED AT 250 WORDS)
Explore the source record for details and available documents.
Most natural history data regarding pulmonary stenosis (PS) were obtained from cardiac catheterization studies over 15 to 20 years ago. Selection bias in these studies often excluded patients with mild disease and infants. Today, Doppler echocardiography allows accurate serial assessments of stenotic lesions in patients of all ages. This study evaluates the natural history of PS utilizing serial Doppler examinations in the pediatric population. A total of 147 patients with PS and serial echocardiographic data were identified. Age at initial echocardiogram ranged from 2 days to 15 years, with a mean follow-up of 2.4 years. Sixteen of 56 patients (29%) initially evaluated within 1 month had a > or = 20 mm Hg increase in their peak systolic pressure gradient. Only 7 of 89 patients (8%) initially evaluated over 1 month had a > or = 20 mm Hg increase. Eleven of 40 newborn infants (28%) with mild obstruction had progression to moderate or severe PS compared with 10 of 68 patients (15%) initially evaluated over 1 month. Moderate PS in the newborn was also more likely to progress compared with older children. Of the 16 newborns with > or = 20 mm Hg increases, 8 developed the increase in < or = 6 months. In contrast, no patient aged >2 years whose initial gradient was <50 mm Hg developed severe PS. Mild PS may not be static, particularly in young infants. Progression in this age group occurs more often and more rapidly than in older infants and children.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
At the DIF Children's Hospital, 12 patients with pulmonary stenosis (PS) were studied. The values of the systolic pressure of right ventricle (SPRV) varied between 69 to 300 mmHg, showing a direct relationship with age. Weight and height were not related to the degree of PS. Five patients presented dyspnea and 3 of them also presented cyanosis, but seven were asymptomatic. Symptoms appeared in those patients with higher systolic and end diastolic pressure of RV, although the correlation was not significant. The phonocardiogram (PCG) showed a correlation between the duration of the systolic ejective murmur (SEM) and the degree of increase SPRV. The presence of an ejection click did not show a significant correlation with the severity of PS. Furuta's index, the IIA-IIP interval and the IIP/IIA index indicated a substantial corresponding between the SPRV and the transpulmonary gradient, both measured by catheterization. The "a" wave of phlebogram was giant in patients with high SPRV. The calculation of the SPRV by PCG showed a strong correlation with the determination made by catheterization. After surgery the duration of the SEM and Furuta's index decreased in all patients. The ejection click disappeared in 3 patients, becoming apparent in one. The IIA-IIP interval was shorter than before the operation and the phlebogram "a" wave of was reduced, except in one patient. The PCG is a reliable method of great utility for the evaluation of PS.
Successful balloon valvotomy in an adult with calcific pulmonic stenosis is described. The incidence of calcification, and the potential use of this technique in calcified pulmonary valves is discussed.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Data of 12 children (mean age = 3.1 yrs, range 0.4-11.1 yrs) with valvular pulmonary stenosis are reported. Balloon valvuloplasty was attempted for the treatment, first in the pediatric practice in our country. Echocardiography and cardiac catheterisation was used for the indication of the procedure and evaluation of the results. Strong correlation was found between the echocardiographic and haemodynamic data before (correlation coeff. = 0.9) and less strong after (correlation coeff. = 0.4) the procedure. As a result of the balloon dilatation the initial gradient of 62 mmHg (sd = +/- 17 mmHg) decreased to 20 mmHg (sd = +/- 10 mmHg) assessed by invasive technique. The difference is significant, p < 0.001. No major complication was observed. The procedure is recommended for widespread practice both in medical and financial sense.
Critical pulmonary stenosis of the newborn is an emergency and the balloon dilatation can represent its definitive treatment. This procedure has important technical aspects related with the age and weight of patients and to anatomical factors that contributes to the obstruction. We present the case of a 20 days old newborn with this problem, in whom the use of an arterio-venous loop through the ductus arteriosus allowed the passage of balloon catheters of gradually increasing diameter until a balloon/pulmonary annulus index of 1.4 was reached. This procedure can be performed safely in cases in whom the common technique is difficult to apply. The procedure allows a successful valvular dilatation.
Explore the source record for details and available documents.
Explore the source record for details and available documents.