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Results for “Paralyses, Familial Periodic”

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At least 127 records · Page 7Linked to original sources
PubMed1988

The periodic paralyses.

Patient history and examination often provide sufficient diagnostic clues to allow appropriate classification of the patient with one of the primary periodic paralyses. This article reviews these disorders, their treatment, and the use of provocative testing in their diagnosis. Dysfunction of the muscle membrane sodium channel may be a "final common pathway" pathogenetic mechanism for many of the periodic paralyses.

Humans↗
PubMed1983

Interictal conduction slowing in muscle fibers in hypokalemic periodic paralysis.

Conduction velocity in muscle fibers of the short head of biceps brachii was reduced between attacks in all the affected members of a family suffering from hypokalemic periodic paralysis. This finding represents a further evidence of a primary alteration of sarcolemmal function in this disease. Interictal conduction slowing in muscle fibers is consistent with the prevailing pathophysiologic hypothesis, which considers an increased membrane permeability to sodium ions as the fundamental defect underlying all forms of familial periodic paralysis.

Female↗
PubMed1977

Familial hypokalaemic periodic paralysis in papua nuiginians--a reappraisal.

Studies of 11 Papua Nuiginians with recurrent muscular paralysis are presented. The clinical pattern, the geographical clustering, the lack of relation with dietary change, and the normal aldosterone levels in two patients support the view that it is a variant of familial hypokalaemic periodic paralysis.

Adolescent↗