[Spasmophilia--an expression of anxiety].
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Spasmorhythmia (SR) can be defined as repetitive electromyographic activity lasting for longer than 4 min under conditions of cuff-induced ischemia. In a study on more than 180 'normal' subjects, this electrical anomaly was found in 21% of men and 30% of women, and was independent of age. Spontaneous variation in SR several hours or weeks apart is relatively slight, an average of 2 min, with the electrical diagnosis being confirmed by a second test in three quarters of cases. Correlations between SR and magnesium metabolism have not been proved as yet. SR has no pathological significance on its own. It assumes diagnostic importance when found in association with various vascular conditions; when found in association with a characteristic symptomatology, it may be used to support a diagnosis of latent tetany.
In a group of spasmophilic subjects, symptoms imputable to the syndrome were compared with EMG signs of ischemic neuromuscular hyperexcitability, to evaluate their significance by logistic statistical analysis. Subjects with a duration of postischemic EMG spontaneous activity greater than the mean of normal values + 2.5 DS were considered positive for a spasmophilic syndrome. The following symptoms were selected as positive by the analysis: palpitations, nail and hairs abnormalities, headache, lipothymia; thermoregulation disorders and tremors were negatively related to the syndrome, while sleep disorders and asthenia emerged as positive in the logistic analysis but not significantly so.
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