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At least 127 records · Page 7Linked to original sources
PubMed1976

Aging changes in intervertebral discs and spondylosis in Chinese hamsters.

Vertebrae and intervertebral discs of Chinese hamsters, a species of rodents that develop spontaneous diabetes, were investigated for age-linked changes and for the occurrence of spondylosis. Aging changes in the intervertebral discs were similar in diabetic and nondiabetic animals. The incidence of spondylosis was significantly increased and its onset was accelerated in the diabetic animals. The mechanisms operative in the pathogenesis of the lesions and their relation to the human disease are discussed.

Aging↗
PubMed1999

Kinematic MR imaging in surgical management of cervical disc disease, spondylosis and spondylotic myelopathy.

PURPOSE: To estimate the clinical value and influence of kinematic MR imaging in patients with degenerative diseases of the cervical spine. MATERIAL AND METHODS: Eighty-one patients were examined with a 1.5 T whole body magnet using a positioning device. Cervical disc disease was classified according to clinical and radiographic findings into 4 stages: stage I=cervical disc disease (n=13); stage II=spondylosis (n=42); stage III=spondylosis with restricted motion (n=11); and stage IV=cervical spondylotic myelopathy (n=15). Findings on kinematic MR images were compared to those on flexion and extension radiographs, myelography, CT-myelography and static MR imaging. Furthermore, the influence of kinematic MR imaging on surgical management and intra-operative patient positioning was determined. RESULTS: Additional information obtained by kinematic MR imaging changed the therapeutic management in 7 of 11 (64%) patients with stage III disease, and in 13 of 15 (87%) patients with stage IV disease. Instead of an anterior approach, a posterior surgical approach was chosen in 3 of 11 patients (27%) with stage III disease and in 6 of 15 patients (40%) with stage IV disease. Hyperextension of the neck was avoided intra-operatively in 4 patients (27%) with cervical spondylotic myelopathy, and in 1 patient with stage II (2%) and in 1 patient with stage III (9%) disease. Kinematic MR imaging provided additional information in all patients with stages III and IV disease except in 1 patient with stage III disease, when compared to flexion and extension radiographs, myelography, CT-myelography and static MR examination. CONCLUSION: Kinematic MR imaging adds additional information when compared to conventional imaging methods in patients with advanced stages of degenerative disease of the cervical spine.

Cervical Vertebrae↗
PubMed2002

Role of corpectomy in cervical spondylosis.

The management of cervical spondylosis has evolved over the past several decades. Surgical decompressive and stabilization techniques have become more widely accepted for use in patients with intractable pain or neurological deficits. Advances in neuroimaging, surgical technique, and surgery-related technology including the operating microscope and anterior fixation devices have all contributed to the expanding role of surgery for the treatment of this condition. In this paper the author will focus on the role of corpectomy as a surgical option for managing cervical spondylosis.

Cervical Vertebrae↗
PubMed1976

A new approach to the surgical treatment of lumbar spondylosis.

The authors discuss routine removal of inferior articular processes and their facets during laminectomy, with wide visualization of the lumbar nerve roots, which has proven to be most successful in relief of the symptoms of lumbar spondylosis. No instance of postoperative vertebral instability has been found. In a consecutive series of 70 patients averaging 58.3 years of age, 91% of patients adequately followed did well. Of six patients who did poorly, three had apparent explanations and, presumably, such errors are avoidable. Despite the generally advanced age of this series (12 patients aged over 70 years) there was no mortality or undue morbidity. Patients previously operated on for disc herniation, as a group, were somewhat younger and the spondylosis tended to be more localized (to the area of previous surgery) than in patients operated on for the first time.

Adult↗
PubMed1977

Brown-Séquard syndrome and cervical spondylosis.

Six patients with a rapidly progressive myelopathy of the Brown-Séquard type are presented (two in detail). Their clinical history, results of laboratory investigations, and surgical exploration revealed cervical spondylosis as the sole cause of this syndrome. We believe that a rapidly progressive myelopathy of Brown-Séquard type even in younger individuals, is often a presenting clinical feature of cervical spondylosis.

Adult↗
PubMed1982

Clinical recording of pressure on the spinal cord and cauda equina. Part 3: pressure on the cervical spinal cord during endotracheal intubation in patients with cervical spondylosis.

Pressure on the spinal cord with the neck in the extended position for endotracheal intubation was recorded in eight patients with a narrow spinal canal due to cervical spondylosis. Pressures up to about 1400 mm H2O were recorded. Longitudinal skeletal traction with the tong placed frontally reduced the pressure on the spinal cord in all patients. When longitudinal skeletal traction was applied, the stress of the neck extension was probably in part transferred from the lower cervical spine where the canal was narrow to the upper cervical spine with the more spacious canal. Placing the tong for longitudinal skeletal traction frontally when performing endotracheal intubation is advocated in patients with cervical spondylosis and probably also in patients with injuries of the lower cervical spine.

Cauda Equina↗
PubMed1985

CT myelography with intramedullary enhancement in cervical spondylosis.

The authors describe seven cases of cervical spondylosis in which small high-density areas were detected in the spinal cord on delayed computerized tomographic (CT) myelography. These high-density areas are believed to represent cavities or areas of cystic necrosis. In all seven cases the cervical spinal canal was narrow, and the spondylosis was located at multiple levels, causing a so-called "pincer effect." On the CT scans the high-density areas resembled fried eggs in the gray matter. These areas were localized near the abnormal cervical discs. In two cases in which the Brown-Séquard syndrome was noted, the symptoms could be attributed to the morphology of the high-density area on the affected side of the cord. Following decompressive surgery, most of the symptoms improved except for numbness of the upper extremities and motor weakness of hands.

Aged↗
PubMed2002

Preliminary experience with the DOC dynamic cervical implant for the treatment of multilevel cervical spondylosis.

OBJECT: Despite the wide use of anterior cervical instrumentation in the management of multilevel cervical spondylosis, the incidences of pseudarthrosis and instrument-related failure remain high. The use of a dynamic implant may aid in the prevention of these complications. The purpose of this study was to evaluate the DOC dynamic cervical implant in the treatment of multilevel cervical spondylosis. METHODS: The authors evaluated 34 cases in which anterior multilevel cervical decompression and fusion were performed using the DOC Ventral Cervical Stabilization System. Postoperatively, and at each follow-up visit, the sagittal angle and the degree of subsidence that developed were measured. Fusion rates and clinical outcomes were also evaluated. The mean postoperative sagittal angle was 14 degrees of lordosis. The mean change in the sagittal angle during the follow-up period was 0.4 degrees of lordosis. By 6 months postoperatively some subsidence had occurred in most patients, with no subsidence occurring in only 15%. By 3 months greater than or equal to 2 mm of subsidence was demonstrated in 61% of cases. The overall fusion rate was 91%. In the majority of patients (79%) symptoms were judged to be improved or resolved. CONCLUSIONS: The DOC dynamic cervical implant permitted controlled subsidence and prevented progression of kyphotic deformity. There was one construct failure (related to a motor vehicle accident) and an overall fusion rate of 91%. The DOC implant is a safe and effective cervical construct for multilevel spondylotic disease.

Cervical Vertebrae↗
PubMed2005

Diaphragmatic paralysis caused by cervical spondylosis. Case report.

The authors describe a rare case of diaphragmatic paralysis caused by cervical spondylosis. A 64-year-old man presented with dyspnea as well as cervical radicular pain and left-sided upper-extremity motor weakness. Chest radiography revealed elevation of both sides of the diaphragm. All symptoms were ameliorated immediately after cervical laminoplasty, and spirometry revealed improvement of ventilatory function 6 months after surgery. Cervical spondylosis should be considered a factor that can cause respiratory dysfunction.

Cervical Vertebrae↗
PubMed1976

Hemiparesis in cervical spondylosis.

Two patients with hemiparesis were thought to have intracranial lesions. Cervical spondylosis was discovered, and the condition of both patients improved after laminectomy. Although it has been rarely emphasized in the past, cervical spondylosis should be considered in the differential diagnosis of hemiparesis.

Cervical Vertebrae↗
PubMed1975

[Myelographic findings in multiple sclerosis in combination with cervical spondylosis].

Differential diagnostic problems are considered in 8 patients suffering from multiple sclerosis and cervical spondylosis simultaneously. When a clinical suspicion for multiple sclerosis is combined with a relatively normal sagittal diameter of the cervical vertebral canal, myelographic findings due to cervical spondylosis must be evaluated carefully.

Brachial Plexus↗
PubMed1975

[The protrusion of thoracic intervertebral disc-thoracic spondylosis (author's transl)].

The protrusion of cervical intervertebral discs was divided into three pathological entities by Spurling; soft disc, hard disc and spondylosis. We applied these concept to the dorsal intervertebral disc disease and treated two cases of thoracic spondylosis. Case 1. A 41-year-old male entered the hospital because of the gradual progression of weakness of both legs of two months' duration. Since ten days before admission he had not had an errection and had not been to able to walk and micturate. He also complained of paresthesia radiating down the abdomen into both legs. There were no visceral complaints. Neurological examination revealed severe weakness of both legs with bilateral impairment of deep sensations and hypalgesia up to the level of T6. Reflexes in both legs were hyperactive with sustained clonus. Plantar responses were extensor bilaterally. Though plain X-rays showed no changes, tomography revealed a calcified intervertebral spur formation at the T5-6 interspace. A myelogram showed a complete block of the contrast medium at the level of the upper part of T6. The patient underwent a complete laminectomy from T3 through T6 and extradural anterior decompression with the removal of the calcified disc at the T5-6 interspace using an air drill. Postoperatively, he demonstrated an immediate improvement in sensation and a gradual recovery in motor power. At his follow-up examination 14 months after surgery he could walk without assistance. Case 2. A 47-year-old dwarfish woman (130 cm) with a low back pain and difficulty in walking for a few years duration was admitted. A few months before admission she felt pain at her left lateral abdomen. There was weakness of both legs, greater in the left. Reflexes in her left lower extremity were hyperactive with sustained clonus. Plantar responces were flexor bilaterally. Palin X-rays showed scoliosis of thoracic spine with the top at T7 level and calcified intervertebral masses at T10-11, T11-12 and T12-L1, extending into the canal that were confirmed more clearly by tomography. Myelography by a cisternal puncture disclosed a complete block at the level of T10. The patient underwent total laminectomy of T9 through L2 and extradural anterior decompression with the removal of calcified discs. At her follow-up examination 12 months after surgery she could walk for herself with some residual neurological signs, minimal weakness in the right leg and hypesthesia up to the level of T12 in the left. We have discussed the incidental, related diagnostic and operative problems of this disease.

Adult↗
PubMed2002

[High frequency color duplex sonography in cervical spondylosis].

OBJECTIVE: To observe the morphological structure and hemodynamic changes of the vertebral artery in cervical spondylosis by high frequency color duplex sonography. METHODS: We measured 138 cases of cervical spondylosis at the vertebral artery with a 7.5-10 MHz probe of high frequency color duplex sonography, to determine morphological changes, Diameter(D), Velocity(V), Blood flow volume, and Resistance index(RI) and (PI). A controlled analysis was performed at the same time. RESULTS: The measurement showed that the vertebral arteries of the patients bent more severely than the controlled group. There was a significant difference between the two groups (P < 0.01) in Diameter (D), Velocity (except mean velocity), Blood flow volume, and resistance index (RI) and (PI). CONCLUSION: High frequency color duplex sonography has provided clinical judement on morphological and blood flow dynamic parameter changes of the vertebral artery with a valuable objective basis.

Adult↗
PubMed2003

[A case of embolic infarction originating from extracranial vertebral artery stenosis by cervical spondylosis at C5/6: its pathogenesis and surgical treatment].

We report a case of right brainstem and cerebellar infarction induced by head rotation. The infarction was due to an artery to artery embolism originating from extracranial vertebral artery stenosis resulting from C5-6 cervical spondylosis. A-64-year-old man with cervical spondylosis experienced swallowing difficulty and vertigo while eating dinner. Neurological examination at admission indicated lateral medullary syndrome (Wallenberg syndrome). MRI (FLAIR) revealed multiple high-intensity signal areas in the right lateral medulla and the cerebellar hemisphere in the territory of the posterior inferior cerebellar artery (PICA). Right vertebral angiogram demonstrated marked stenosis in the neutral position and occlusive changes with head rotation to the right (30 degrees) at C5-6. Rotation induced substantially delayed filling of the right vertebral artery. To remedy this, we resected the osteophyte, fused the uncovertebral joint and connective tissue adhering tightly to the right vertebral artery at C5-6 level, and unroofed the transverse foramens at C5 and C6. Post-operative angiogram confirmed the disappearance of marked stenosis and improved antegrade filling of the right vertebral artery. In the present report, the pathogenesis and surgical treatment of this particular case are discussed.

Adult↗
PubMed2005

[The study of the C5 nerve root palsy after surgery of cervical spondylosis].

OBJECTIVE: To explore the clinical features, treatment and prognosis of the C5 palsy after surgery of cervical spondylosis. METHODS: Two hundred and twenty-three cases treated from March 1994 to October 2003 were retrospectively reviewed. RESULTS: Seven of the 223 cases developed the complication of C5 palsy, manifesting the paresis of the deltoid muscle as well as the sensory deficits and (or) intractable pain in shoulder. The incidence was 3.1%. In this study, 2 cases occurred in the anterior subcorpectomy, 5 cases developed in the laminoplasty with 1 case on the opened side, 3 cases on the hinged side and 1 case on both sides. All the 7 cases with the C5 palsy recovered within 2 weeks to 6 months. CONCLUSION: The C5 palsy can develop either anterior decompression or posterior open-door laminoplasty of cervical spondylosis. Generally speaking, patients with postoperative C5 palsy can be cured by conservative measures. And prognosis is good.

Adult↗
PubMed2004

[Epidemiologic research on the clinical features of patients with cervical spondylosis].

OBJECTIVE: To investigate the clinical features of patients with cervical spondylosis. METHODS: Questionnaires were provided and X rays were examined in 1 009 people with different occupations, ages, and sexes. RESULTS: All the patients were diagnozed as cervical spondylosis. Of them, cadres occupied 78.83%, technologists made up 74.21%, and accountants 58.70%; nervous and long-time working people accounted for 59.75%; high and middle pillow-lovers occupied 80.03%. Imaging features: most of the degenerative changes of cervical spine were located between C5-6 (40.79%), C4-5 (26.29%), and C6-7 (18.20%). Patients with vertebral osteophyte were 65.75%, intervertebral space narrow 36.87%, intervertebral foramen narrow 29.19%, and physiological curve change 31.03%. CONCLUSION: This epidemiologic investigation is important, which can further understand the cause of cervical spondyiosis, and strengthen its prevention and treatment.

Adult↗
PubMed2005

[Influence of positional blood flow disorders in the vertebral and basilar arteries on the prevalence of vertigo in patients with cervical spondylosis].

The aim of present study was to characterize the association between prevalence of vertigo and age, grade of radiological changes and positional vertebral (VA) and basilar artery (BA) flow lesion in patients with cervical spondylosis. We examined 80 patients with radiological evidence of cervical spondylosis. Forty patients complained positional vertigo. Patients with neurological symptoms were excluded from the study. ENG was used to exclude patients with another causes of vertigo. TCD evaluations of the distal part of VA and the proximal part of BA were performed with a 2-MHz probe via the suboccipital window. We showed significant and independent association between prevalence of vertigo and age, grade of radiological changes, and positional vertebral and basilar artery flow lesion velocity in multivariate logistic regression model. Spondylotic-induced VA compression may be the reason of decreased blood flow velocity in the basilar artery during head rotation, causing positional vertigo.

Adult↗