PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Tooth”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 127 records · Page 7Linked to original sources
PubMed1984

Biosynthesis of tooth germ proteins in vitro: a fast quantitative extraction of amelogenins from intact hamster molar tooth germs.

A three step extraction procedure was carried out on intact hamster molar tooth germs in vitro labelled with 32PO4 and/or 3H-proline, in order to quantify separately the synthesis of dentine matrix (collagen) and the proline rich enamel matrix proteins. The extraction was based on the high solubility of the proline rich enamel matrix proteins compared with the relatively insoluble dentine matrix collagens. Pretreatment with 10% trichloroacetic acid (step 1) demineralized and removed the non-incorporated amino acids and/or small sized peptides. A consecutive water extraction (step 2) removed a large percentage of the phosphorylated amelogenins as assessed by SDS-urea-polyacrylamide-electrophoresis and amino acid analyses. Collagenase digestibility data showed that only small amounts of collagens were present in this extract. Further extraction with 10% formic acid (step 3) released only small amounts of amelogenins from the explants but also increased contamination with collagens and another predominantly low molecular components. Most of the 3H-activity remaining in the residues was found in the collagenase labile material and was considered to be an appropriate measure for production of dentine collagens. On the other hand, the residues also contained small amounts of 3H-labelled material with the same electrophoretic mobility as amelogenins but had much more 32P-activity than the amelogenins derived from the water and formic acid extracts. It is suggested that this material in the residues probably contains the crystal bound enamel matrix proteins.

Amelogenesis↗
PubMed1976

[Tooth preservation and tooth extraction within the framework of prevention-oriented treatment planning].

The improvement in efficiency of prosthodontic therapy is linked to a strategic basic conception, the question of tooth preservation and extraction being of particular importance. The decisive criterion may consists in answering the question whether the step intended might contribute to structure preservation and function securing till old age or might be detrimental to these objective. The stomatologist may play a passive or an active role in the strategy of treatment.

Adolescent↗
PubMed1996

Recombination hot spot in a 3.2-kb region of the Charcot-Marie-Tooth type 1A repeat sequences: new tools for molecular diagnosis of hereditary neuropathy with liability to pressure palsies and of Charcot-Marie-Tooth type 1A. French CMT Collaborative Research Group.

Charcot-Marie-Tooth type 1A (CMT1A) disease and hereditary neuropathy with liability to pressure palsies (HNPP) are autosomal dominant neuropathies, associated, respectively, with duplications and deletions of the same 1.5-Mb region on 17p11.2-p12. These two rearrangements are the reciprocal products of an unequal meiotic crossover between the two chromosome 17 homologues, caused by the misalignment of the CMT1A repeat sequences (CMT1A-REPs), the homologous sequences flanking the 1.5-Mb CMT1A/HNPP monomer unit. In order to map recombination breakpoints within the CMT1A-REPs, a 12.9-kb restriction map was constructed from cloned EcoRI fragments of the proximal and distal CMT1A-REPs. Only 3 of the 17 tested restriction sites were present in the proximal CMT1A-REP but absent in the distal CMT1A-REP, indicating a high degree of homology between these sequences. The rearrangements were mapped in four regions of the CMT1A-REPs by analysis of 76 CMT1A index cases and 38 HNPP patients, who where unrelated. A hot spot of crossover breakpoints, located in a 3.2-kb region, accounted for three-quarters of the rearrangements, detected after EcoRI/SacI digestion, by the presence of 3.2-kb and 7.8-kb junction fragments in CMT1A and HNPP patients, respectively. These junction fragments, which can be detected on classical Southern blots, permit molecular diagnosis. Other rearrangements can also be detected by gene dosage on the same Southern blots.

Charcot-Marie-Tooth Disease↗
PubMed2001

Bodily tooth movement through the maxillary sinus with implant anchorage for single tooth replacement.

Movement of teeth through anatomic limitations, such as the maxillary sinus, can be a reliable therapeutic protocol if suitable force systems are used. We report here the outcome of a treatment based on this concept. The patient exhibited pneumatization of the maxillary sinus resulting from earlier extractions. She was treated using an endosseous implant inserted in the retromolar region to serve as orthodontic anchorage and a T-loop appliance fabricated from TMA wire to bodily move an upper second premolar through the sinus. After 6 months, at the end of the displacement, a titanium implant was inserted in the alveolus of the moved tooth and a single crown restoration was placed. The premolar moved through the sinus maintaining its support apparatus and bone. At the end of treatment the implant used for anchorage was still osseointegrated.

Journal Article↗
PubMed2002

Analysis of cDNAs from a mouse embryo tooth library: identification of novel genes during tooth development.

Signaling molecules, their receptors, and target genes from pathways and networks regulate the development of the tooth from initiation through cell differentiation. In order to identify genes involved in odontoblast and ameloblast differentiation, we constructed a cDNA library from E19.5 mouse molars. In this work, we report the partial cDNA sequences of 10 noncharacterized genes and we show cell expression of the transcripts on mouse embryo molars by in situ hybridization.

Animals↗
PubMed1982

Effect of tetracycline on gingival inflammation and alveolar bone resorption in beagles: an individual tooth by tooth analysis.

The effect of systemic tetracycline on gingival inflammation and alveolar bone resorption was studied in beagle dogs. Seventeen dogs were divided into three groups receiving either no treatment, 250 mg tetracycline HCl, or 500 mg tetracycline HCl daily. The severity of gingival inflammation and activity of alveolar bone resorption during a 6-month pretreatment period was compared to a 24-month treatment period for each individual tooth studied. In the first 12 months of treatment there was a significant decrease in the severity of gingival inflammation and the activity of alveolar bone loss in the tetracycline treated dogs. By 24 months of treatment increased gingival inflammation and rate of bone loss was evident in the treated dogs. In the untreated control dogs there was a statistically significant association between the severity of gingival inflammation and activity of alveolar bone resorption about the teeth studied. In the tetracycline treated dogs, no such association existed.

Alveolar Process↗
PubMed1997

Single-unit resin-bonded bridges using the natural tooth or a denture tooth.

Resin-bonded bridges were first described by Rochette in 1973. In the following year the author had occasion, for the first time, to experiment with a single-unit resin-bonded bridge (RBB) which employed the exfoliated natural tooth as a pontic. That 'temporary' measure gave good service for 17 years and was the precursor of a number of successful RBBs which utilized natural or denture teeth. The very simple method described offers the means of preserving the patient's natural appearance, thereby maintaining the psychological well-being of the patient. It is particularly applicable in patients who present with gross loss of periodontal support and where a conventional RBB or fixed bridge may be contra-indicated for personal or clinical reasons. It is not time consuming or clinically demanding. It has a high degree of patient acceptance and satisfaction. The contiguous teeth, involved as abutments, appear to be beneficially affected.

Acid Etching, Dental↗