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Investigation of the probable causes of specific childhood disabilities in eastern Afghanistan (preliminary report).

To identify risk factors likely to cause developmental disabilities and to generate hypotheses for a further study of risk factors predisposing to disability and slow mental and physical development. Mothers and children attending/visiting the Sandy Gall's Afghanistan Appeal (SGAA) clinics in the East Zone of Afghanistan. The main outcome measures, developmental disabilities, cerebral palsy (CP), club foot, CDH and polio. Results, 37.5% of the disabilities were present at birth, 46% of the disabled children were born from parents who are 1st cousin which was confirmed by computing chi2 value, which is 10.87 with one degree of freedom. 58.3% of the disabled children were born from parents who lack antenatal care. 22.4% of the pregnant women in the defined population had antenatal checkups, and 97% of the mothers in the defined population are illiterate, 52% of the children found with CP specific and mental retardation. 25% were with delayed physical and mental development. 13% were with CP specific and 10% were club foot. 2% of the children were visually handicapped, 9% with hearing impairment. 61% of children were from Nangarhar, 25% from Laghman and 14% from Kunar.

Adolescent↗

Definition of abnormal focused affections and exploration of their relation to abnormal stereotyped behaviors.

The relation between abnormal stereotyped behaviors and abnormal focused affections (i.e., abnormally consistent preferences for specific objects, symbols, and/or physical locations) was examined in 20 children with developmental disabilities. Results indicated that (a) all children who exhibited abnormal focused affections exhibited stereotypies; (b) abnormal focused affections could be studied reliably in individuals with developmental disabilities through the use of direct time-sampling observations, naturalistic observations, and informant reports; and (c) developmental age was significantly related to the frequency of (and the number of different) stereotyped behaviors and the frequency of nonstereotyped (i.e., developmentally appropriate) behaviors exhibited across the sample. Results also provide preliminary support for the notion of a general stereotyped behavioral repertoire in individuals with developmental disabilities.

Adolescent↗

Effect of preventive dentistry training program for caregivers in community facilities on caregiver and client behavior and client oral hygiene.

The influx of persons with developmental disabilities into community-based programs has required the development, expansion and improved integration of community-based services. The role of caregivers in these community settings has become pivotal. However, with regard to daily activities, oral hygiene is often a low priority. Few attempts have been made to study caregiver participation in oral disease prevention and practices. This study evaluated the effects of an indirect training program, where caregivers were trained but the ultimate effects were demonstrated in adult clients. In addition, these effects were demonstrated in community care settings. A multiple baseline design, across three group homes, included 11 adult clients with developmental disabilities. This study evaluated the effects of training, instruction to use training and coaching on the presence of caregivers during oral hygiene sessions, the duration of toothbrushing and plaque scores of the clients. The results of this investigation demonstrated that there was an increase in caregiver presence and duration of brushing with a concurrent decrease in plaque scores. Caregivers responding to social validation questionnaires believed that 8 out of 11 clients had increased skills. This study demonstrates that caregiver training, combined with specific instructions to use training information and coaching of caregivers, can have a positive impact on the oral health of individuals with developmental disabilities living in community settings.

Adult↗

Variation in health conditions among groups of adults with disabilities in primary care.

The literature on the health of adults with disabilities focuses on one disability compared to a comparison group. This study allows cross disability comparisons with the hypothesis. Adults with disabilities had higher odds of having common health conditions, compared to adults without disability in the same practice. A retrospective record review of 1449 patients with disability and 2084 patients without disability included individuals with sensory impairments (n = 117), developmental disabilities (n = 692), trauma-related impairments (n = 155) and psychiatric impairments (n = 485). The only two health conditions with statistically significantly increased odds for all groups with disabilities were dementia and epilepsy. Patients with developmental disabilities were less likely to have coronary artery disease, cancer, and obesity. Those with sensory impairments had increased odds for congestive heart failure, diabetes, transient ischemic attacks and death. Patients with trauma disabilities had increased odds for chronic obstructive pulmonary disease, and depression. Finally, psychiatric patients had increased odds for most of the investigated condition. In conclusion, there were many similarities in the risk for common health conditions such as asthma, cancer, coronary artery disease, depression, hypertension, and obesity, among patients with and without disability. Some of the conditions with increased odds ratios, including depression, seizures, and dementia are secondary to the primary disability.

Adult↗

Remediating the core deficits of developmental reading disability: a double-deficit perspective.

The double-deficit hypothesis (Wolf, 1997; Wolf & Bowers, 1999, this issue) contends that deficits in phonological awareness and deficits in visual naming speed represent two independent causal impediments to reading acquisition for children with developmental reading disabilities (RD). One hundred and sixty-six children with severe RD from 7 to 13 years of age were classified into three deficit subgroups according to a double-deficit framework. A total of 140 children with RD, 84% of the sample, were classified; 54% demonstrated a double deficit (DD), 22% a phonological deficit only (PHON), and 24% a visual-naming speed deficit only (VNS). Diagnostic test profiles highlighted the joint contributions of the two core deficits in depressing written language acquisition. The children in the DD group were more globally impaired than those in the other subgroups, and the VNS group children were the highest achieving and most selectively impaired readers. Following 35 hours of word identification training, sizable gains and significant generalization of training effects were achieved by all subgroups. A metacognitive phonics program resulted in greater generalized effects across the domain of real English words, and a phonological training program produced superior outcomes within the phonological processing domain. The greatest non-word reading gains were achieved by children with only phonological deficits.

Adolescent↗

Group action planning as a support strategy for Hispanic families: parent and professional perspectives.

Focus group interviews were conducted to obtain participants' preliminary reactions to the responsiveness of group action planning, a person-centered planning approach, as a support strategy for Hispanic families of individuals with disabilities. Focus group participants were 38 Hispanic parents of youth/young adults with developmental disabilities and 22 professionals who provided support services to Hispanic youth/young adults with developmental disabilities and their families. Both constituency groups identified advantages and disadvantages of group action planning. We focus our key recommendations on the implications of this information for education and human service systems as well as directions for future research.

Adolescent↗

Relative and attributable risks for moderate to profound bilateral sensorineural hearing impairment associated with lower birth weight in children 3 to 10 years old.

OBJECTIVE: To determine the prevalence, relative risks, and attributable fractions for congenital bilateral sensorineural hearing impairment in relation to lower birth weight among children born in the 1980s and living in the metropolitan Atlanta area from 1991 through 1993. METHODS: We used the population-based, active case ascertainment Metropolitan Atlanta Developmental Disabilities Surveillance Program that conducts surveillance in the five-county metropolitan Atlanta area. Hearing impairment was defined as a bilateral, pure-tone hearing loss at frequencies of 500, 1000, and 2000 Hz averaging 40 dBs or more, unaided, in the better ear. Case children, 3 to 10 years of age, with sensorineural loss of presumed congenital origin were included in these analyses (n = 172). Prevalence rates and relative risks were computed for various birth weight categories by hearing level, sex, race, the presence or absence of coexisting developmental disabilities, and gestational age. Attributable fractions were calculated for low birth weight and very low birth weight children by race. RESULTS: The overall prevalence rate of presumed congenital bilateral sensorineural hearing impairment was 5.3 cases per 10 000 3-year survivors. The prevalence was 4.1 per 10 000 among children weighing >/=4000 g, 3.7 per 10 000 among those weighing 3000 to 3999 g, 6.6 per 10 000 among those 2500 to 2999 g, 12.7 per 10 000 among those 1500 to 2499 g, and 51.0 per 10 000 among those <1500 g. There was virtually no difference in birth weight-specific rates of hearing impairment across three hearing levels. The presence of coexisting developmental disabilities was associated with a much stronger inverse trend with birth weight. Black children weighing <2500 g had much higher rates of hearing impairment than comparable white children. The overall percentage of moderate to profound congenital bilateral sensorineural hearing loss in the entire study population that was attributable to children weighing <2500 g or <1500 g was estimated to be 18.9% and 9.4%, respectively. Prematurity did not alter the magnitude of risk among children weighing <2500 g. CONCLUSIONS: The results presented here provide recent estimates of the rates, relative risks, and attributable fractions for congenital bilateral sensorineural hearing impairment by birth weight among children in the United States. The elevated relative risks among children weighing 2500 to 2999 g and 1500 to 2499 g may have implications for future newborn hearing screening criteria.

Birth Weight↗

A rationale for family therapy specialization in early intervention.

Over the past two decades, professionals providing intervention to families with children with disabilities have witnessed a philosophical shift from individually oriented care to family-centered care. Although the relevance of family therapy to these families has been formally acknowledged through the Individuals with Disabilities Education Act (IDEA), the integration of the fields of family therapy and developmental disabilities has not yet occurred to any significant degree. Awareness of critical issues associated with developmental disabilities and the potential impact on the family system is vital to the process of family-centered intervention. In this paper we address the need for family specialists to become knowledgeable about early intervention considerations relevant to young children with disabilities and their families.

Child↗

An ordinal pattern analysis of four hypotheses describing the interactions between drug-addicted, chronically disadvantaged, and middle-class mother-infant dyads.

This study investigated mother-infant interactions in 18 dyads. All participants were African American and enrolled in an early intervention program because the infants (2-26 months of age) had developmental disabilities or were at high risk for developmental disability. Some mothers had used drugs during their pregnancy, and all mothers were of low or middle socioeconomic status. Dyads were videotaped interacting at 4 different times, separated by at least 5 months in time. Videotapes were rated in terms of infant involvement and maternal responsivity in the interaction. 4 hypotheses concerning the pattern of maternal interaction across time were tested using ordinal pattern analysis. The hypothesis that mothers would become less responsive to infants over time (HD) as a function of drug addiction, poverty, or serious developmental delay was supported for only 4 of the 18 dyads. There was support for the hypothesis (H(I)) that mothers naturally increase their responsivity over time (N = 6) and support for the hypothesis (HT) that mothers' interactive sensitivity fluctuates in relation to infants' involvement in the interaction over time (N = 7). Ordinal pattern analysis has advantages in determining how well competing hypotheses describe individuals within populations relative to approaches that identify differences that apply to entire populations.

Adult↗

Estimating treatment and treatment times for special and nonspecial patients in hospital ambulatory dental clinics.

Increased time to treat the special patient is often cited as a barrier to dental care. The purpose of this study was to analyze the separate and combined effects of differences in dental services planned, services actually performed, and differences in treatment time requirements between special and nonspecial patients in a hospital ambulatory clinical setting. Data for this study were obtained from the UCLA evaluators of the RWJ-funded Hospital-Sponsored Ambulatory Dental Services Program (HSADSP). The results show that special patients require more dental treatment than nonspecial patients for advanced dental disease (i.e., periodontics, surgery, and removable prosthetics) and that they receive more of such services. The study also found that special patients should not be viewed as a homogeneous group when evaluating dental needs and required time resources for treatment. Three subgroups of special patients were identified: developmentally disabled, severely compromised, and moderately compromised. The developmentally disabled as compared to the nonspecial patients required significantly more (20 percent) provider time in completing a "representative" treatment plan.

Adult↗

Sex hormones and neurotransmitters as mediators for sexual differentiation of the brain.

Sexual differentiation of the brain is regarded as a model for environment-dependent brain development mediated by systemic hormones and neurotransmitters. Abnormal concentrations of systemic hormones and/or neurotransmitters, if occurring during a critical period of brain development, can lead to permanent developmental disabilities of fundamental processes of life. Such developmental disabilities appear to be avoidable, at least in part, by improving the external, i.e. psychosocial and natural environment, or by correcting abnormalities in the internal, i.e. metabolic and hormonal environment and, particularly, by correcting abnormal neurotransmitter concentrations (and/or turnover rates) during brain development.

Acetylcholinesterase↗

Psychometric properties of the Dyskinesia Identification System: Condensed User Scale (DISCUS)

Individuals with developmental disability (N = 400) were assessed with the Dyskinesia Identification System: Condensed User Scale (DISCUS), a 15-item tardive dyskinesia rating scale shortened from the 34-item Dyskinesia Identification System-Coldwater (DIS-Co). Interrater reliability assessments were made for 148 individuals, and 2-week stability (test-retest) assessments were made for 128 individuals. Mean DISCUS total score was 4.1 (SD = 3.5); reliability was .92, p less than .001, and stability was .40, p less than .001. Based upon this study and a larger study of 4,649 individuals with developmental disability, we recommend that clinicians carefully evaluate for tardive dyskinesia any individuals with developmental disability who have been prescribed antipsychotics for greater than 3 months and who score 6 or above on the DISCUS.

Adolescent↗

Test-retest reliability study of the Pennsylvania Bi-Manual Worksample.

Test-retest reliability of a vocational assessment battery called the Pennsylvania Bi-Manual Worksample (PBWS) (Roberts, 1969) was examined in this study. The PBWS was administered to 30 adults with developmental disabilities at two different times, with an interval of 7 to 10 days between administrations. The subjects, who had mild to moderate degrees of mental retardation and ranged in age from 25 to 51 years, were chosen randomly from a group of 95 employees of a sheltered workshop for adults with developmental disabilities in western New York. When the scores from the two test administrations were compared to determine test-retest reliability, a high intraclass correlation value of .98 was found, which indicates that the PBWS provides consistent information about the vocational skills of adults with developmental disabilities.

Adolescent↗

Predicting impact of childhood disability on families: results from the 1995 National Health Interview Survey Disability Supplement.

Predictors of impact on families with a child who has developmental disabilities were examined using results from the 1995 National Health Interview Study Disability Supplement (NHIS-D). From this sample, 505 children who met criteria for a developmental disability were selected. Predictors of impact on these families were investigated across and within racial groups. A multiple regression analysis was completed on the entire sample, which was divided by race/ethnicity. A separate multiple regression analysis was completed for White, African American, and Hispanic families. Predictors of family impact differed for each racial or ethnic group. Results of this study add to the body of literature suggesting that the meaning of disability and its impact on families is culturally relative.

Child↗

Prevalence and descriptive epidemiology of Lennox-Gastaut syndrome among Atlanta children.

PURPOSE: To determine the prevalence and descriptive epidemiology of Lennox-Gastaut Syndrome (LGS) among metropolitan Atlanta children. METHODS: We conducted a population-based study of LGS as part of the Metropolitan Atlanta Developmental Disabilities Study (MADDS) using a multiple-source surveillance system for epilepsy and developmental disabilities. Children were defined as having LGS if they had onset of multiple seizure types before age 11 years, with at least one seizure type resulting in falls, and an EEG demonstrating slow spike-wave complexes (<2.5 Hz). Mental retardation (MR) was not used as a diagnostic criterion. RESULTS: The lifetime prevalence of LGS at age 10 years was 0.26/1,000. Ninety-one percent of those with LGS had MR (IQ < or = 70), and 39% had a history of infantile spasms (IS). A comparison of children with LGS and those with multiple seizure types without slow spike-wave complexes demonstrated that those with LGS were more likely to have MR, history of IS, and multiple disabilities (MR, cerebral palsy, blindness, hearing impairment). Seventeen percent of all children in Atlanta with profound MR (IQ < 20) had LGS. CONCLUSIONS: LGS accounts for only 4% of all childhood epilepsy, yet is a significant contributor to childhood morbidity.

Age Factors↗

Passive and active processes in visuo-spatial memory: double dissociation in developmental learning disabilities.

The distinction between passive and active visuo-spatial memory has been useful to interpret various pattern of deficits reported in individual differences studies. However, this interpretation raises the issue of task difficulty, since active tasks could be failed simply because more complex and the corresponding deficit could reflect a reduced capacity of the system. We describe two children with Nonverbal Learning Disability whose performance provides evidence of a dissociation between passive and active memory processes. One of the children showed a selective impairment in passive tasks and performed flawlessly in active tasks, whereas the second child displayed the opposite pattern. These data suggest that a qualitative difference between passive and active processes does exist and that differences in performance do not reflect a lower/higher level of task difficulty. Further, these data underlie the importance of formulating theoretical models of visuo-spatial memory including both material-related (i.e., visual vs spatial) and process-related (i.e., passive vs active) distinctions.

Adolescent↗

Early learning and adaptive behaviour in toddlers with Down syndrome: evidence for an emerging behavioural phenotype?

BACKGROUND: Though the Down syndrome behavioural phenotype has been described as involving relative strengths in visuo-spatial processing and sociability, and relative weaknesses in verbal skills and motor planning, the early emergence of this phenotypic pattern of strengths and weaknesses has not yet been fully explored. METHOD: In this study, we compared the performance of eighteen 2 to 3-year-olds with Down syndrome to an MA-matched comparison group of nineteen 2 to 3-year-olds with mixed developmental disabilities, and an MA-matched comparison group of 24 children with typical development on two developmental measures: the Mullen Scales of Early Learning and the Vineland Adaptive Behaviour Scales. RESULTS: While the specificity of the Down syndrome profile was (for the most part) not yet evident, results showed that toddlers with Down syndrome in this study did show emerging areas of relative strength and weakness similar to that which has been described in older children and young adults with Down syndrome. This pattern included relatively stronger social skills, weaker expressive language, and poor motor coordination. When this pattern of strengths and weaknesses was compared to the developmental profiles of the two comparison groups, socialisation strengths differentiated the Down syndrome group from the mixed developmental disabilities group.

Adaptation, Psychological↗

A reliability study of measures assessing the impact of deinstitutionalization.

This study examined the reliability of several scales and indices used to measure outcome variables (independence, integration, productivity, and satisfaction) among people with developmental disabilities. A stratified random sample of 112 people was interviewed twice in a two-week period and included equal numbers of verbal and nonverbal consumers, of parent versus other caregivers, and consumers with diagnosed level of retardation being dichotomized into high and low. In addition, half of the interviews were test-retest and half were interrater. After stratifying on these four variables, the sample was chosen randomly within subgroups from the total database of 3,700 individuals who receive services through the Developmental Disabilities Services Division of the Oklahoma Department of Human Services. Correlation and proportion agreement analyses were performed on the pre- and post-tests and comparisons made on each scale for each stratification to examine variations in reliability. Acceptable correlations and matched agreements of at least 0.70 for all measures were found, with the Adaptive Development Scale having particularly strong correlations. In addition, responses from people with developmental disabilities on items of the Consumer Satisfaction scale were acceptably reliable.

Activities of Daily Living↗