PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Compulsive Behavior”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,279 records · Page 71Linked to original sources
PubMed1987

Central muscarinic activation elicits compulsive drinking behaviour in the rat.

Injection of bethanechol into the lateral cerebral ventricle of the rat induces a marked increase in drinking, within 30 min from administration. The response is dose-related, maximal water intake (6.1 +/- 0.55 mL; mean +/- s.e.) occurring at 10 micrograms of bethanechol. Peripheral administration of the agonist (up to 3 mg kg-1 i.p.) fails to elicit drinking. Among several specific antagonists only antimuscarinic drugs produced a significant inhibition of the response, suggesting that the compulsive drinking behaviour in the rat is caused by activation of central muscarinic receptors. The drinking behaviour emerges as a reliable test to assess central muscarinic activity of both agonists and antagonists.

Animals↗
PubMed1987

Compulsive eating and dietary restraint.

The phenomenology of compulsive eating has encouraged comparisons with addictive behaviours and this has suggested that similar underlying processes might be at work. In this paper it is argued that craving for food, preoccupation with eating and loss of control over food intake represent a natural psychobiological adaptation to sub-optimal weight and food deprivation. Compulsive eating is therefore best understood in terms of a conflict between a biologically derived drive for food and a culturally derived drive for thinness. Both of these processes have their parallels in the maintenance of dependency disorders. The crucial difference however is that the urge to eat is biologically adaptive, and recovery from compulsive eating depends upon relaxing restraint.

Appetite↗
PubMed1982

Obsessional phenomena and the development of imaginative competence.

Obsessional phenomena are discussed in the light of anxieties arising around the ages 8-12. Three cases of the disappearance of obsessional symptoms are then described. In one remarkable sequence of dreams preceded recovery; in another it was the establishment of a secure therapeutic bond; in the third it was falling in love. The capacity securely to differentiate between fantasy and reality is seen as an essential development element in the recovery from obsessionality.

Adolescent↗
PubMed1984

Hoarding in anorexia nervosa.

A case study of hoarding in a woman with anorexia nervosa is reported. Obsessional and borderline personality characteristics, exacerbated by starvation, may be determinants of hoarding in anorexia nervosa.

Adult↗
PubMed1986

A fresh look at genealogical bewilderment.

The concept of genealogical bewilderment is re-examined in the light of empirical evidence gathered over the past 20 years. It is concluded that, where the quality of surrogate family relationships is sufficient to meet the child's emotional needs, then there is no reason why ancestral knowledge should be a prerequisite of mental health. It would appear that individuals with a spontaneous urge or sometimes even a compulsion to search for their biological relatives are not uncommonly suffering from emotional deprivation. However, this is not to deny the reality of healthy genetic curiosity in children cut off from their roots.

Adoption↗
PubMed1987

Extraversion, neuroticism, obsessionality and the type A behaviour pattern.

A questionnaire consisting of a subset of questions from the Jenkins Activity Survey was given to 135 male military personnel aged between 18 and 25, together with the EPQ and the AI3, an obsessionality scale. A factor analysis of the answers revealed a four-factor structure - impatience, hard-driving competitiveness, speed and emotional unrepression. Neuroticism was found to correlate positively with impatience and speed, but negatively with hard-driving competitiveness, which together with emotional unrepression correlated positively with extraversion. Impatience, speed and emotional unrepression also correlated positively with obsessionality. Obsessionality was the only personality measure to correlate significantly with the total Type A score. The nature of the relationships between the Type A behaviour pattern and the Eysenckian personality measures are discussed.

Adolescent↗
PubMed1987

Paradoxical psychotherapy in a case of transvestism.

Paradoxical psychotherapy succeeded in removing the compulsive element and reducing the guilt attached to transvestism in a male transvestite patient. Cross-dressing at home became acceptable to him and the temptation to cross-dress in public ended. Data suggested three independent motivational systems in this patient.

Adult↗
PubMed1994

On psychoanalysis and non-linear dynamics: the paradigm of bifurcation.

Some of Freud's main theoretical conceptualizations drew on metaphors from 19th century physics. However, though the physics of Freud's era was based on deterministic Newtonian mechanics and equilibrium thermodynamics, his descriptions of the dynamics of instincts, therapeutic change, and even transference, were far beyond this model. Freud's dynamic description of psychic development evokes contemporary theories of irreversible, far-from-equilibrium thermodynamics and non-linear dynamics. The present paper focuses on bifurcation theory, which offers a paradigm for the investigation of unpredictable but deterministic phenomena; this paradigm sheds a retroactive light on the classical psychoanalytical conceptualizations of complemental series, repetition compulsion, transference and cure.

Compulsive Behavior↗
PubMed1969

Compulsive sexual activity induced by p-chlorophenylalanine in normal and pinealectomized male rats.

p-Chlorophenylalanine depletes brain serotonin and induces longlasting sexual excitation in male rats. The effect of p-chlorophenylalanine is potentiated by pargyline. Administration of 5-hydroxytryptophan to rats treated with p-chlorophenylalanine plus pargyline blocks the sexual excitation. p-Chlorophenylalanine also elicits sexual excitation in pinealectomized rats; this effect is not mediated by the lack of indole hormones in the pineal but may be the consequence of depletion of 5-hydroxytryptophan in the brain and the resulting imbalance between 5-hydroxytryptophan and catecholamine activity in the central nervous system.

5-Hydroxytryptophan↗
PubMed1970

Lesch-Nyhan syndrome: preventive control by prenatal diagnosis.

The Lesch-Nyhan syndrome was detected in a fetus at a time sufficiently early to allow termination of the pregnancy. The feasibility of a preventive program for control of a severe sex-linked neurological disease through prenatal diagnosis is thus demonstrated.

Adenine↗
PubMed1970

Biochemically marked lymphocytoid lines: establishment of Lesch-Nyhan cells.

Two lymphocytoid cell lines have been established from a patient with the Lesch-Nyhan syndrome. The cells are deficient in hypoxanthine-guanine phosphoribosyltransferase, as demonstrated by their failure to incorporate [H(3)]hypoxanthine and by their inability to grow in medium in which they were nutritionally dependent upon exogenous hypoxanthine. This represents the first establishment of presumptively permanent human lymphocytoid cell lines that are deficient in a specific enzyme.

Athetosis↗