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[Pathology of developmental defects of the digestive system in human embryos].

Total incidence of the alimentary system defects was 1.05 +/- 0.12% in the non-selected material of medical abortions performed at 5-12 weeks of the intrauterine development. Atresia and stenosis of the duodenum are described for the first time in the embryos of the above age, the possibility of differential diagnosis between physiological and pathological atresia is established. The connection between the ducts of the ring-like head of pancreas and ductus choledochus is observed thus confirming the hypothesis of the additional pancreatic part developing from the ventral anlage. Diagnosis of Mekkel's diverticulum became possible beginning from stage 17. The existence of atresia, stenosis and gastro-intestinal tract doubling in the embryos of the above age indicate that at least some of these defects are not connected with a secondary damage of the intestinal tube due to circulation disturbances, recanalization or inflammation but represent a primary developmental anomaly arising in the early ontogenesis.

Digestive System↗

[Neonatal obstruction].

Neonatal obstruction is a radio-clinical syndrome, common to a wide range of malformative anomalies which alter the normal anatomy or function of the digestive tract at any level. The main etiologies are reviewed with emphasis on specificity due to embryology, topography and clinical presentation. It is relatively easy to diagnose neonatal obstruction and relate it to a definite cause. The successful treatment of such obstruction requires a pluridisciplinary collaboration of specialized teams.

Constriction, Pathologic↗

[The role of developmental disorders of the respiratory, digestive and vascular systems in pathology of the lungs in children].

The results of diagnosis and treatment of bronchopulmonary pathology in 680 children were analysed. It was found that besides developmental anomalies of the lungs and trachea, those of the esophagus, mediastinal organs, diaphragm, and the aorta and its vessels play an important role in the pathogenesis of pulmonary diseases in infants and young children. Traditional and special methods of examination must be used in the diagnosis of these developmental anomalies. Timely correction of the developmental anomalies makes it possible to arrest the bronchopulmonary complications which are associated with them.

Animals↗

[Vomiting in infants].

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Adrenocortical Hyperfunction↗

[Absence of the appendix. Apropos of a case].

A case of congenital absence of the appendix is reported by the authors. It is a very rare anatomic finding, the frequency of which is about 1 p. 100 000. The awareness of this malformation must not authorize young surgeon to forsake a difficult search of the appendix. The diagnosis should not be made unless the entire right colon and the ileo-cecal area are mobilized and thoroughly explored.

Adult↗

[Chronic abdominal pain in childhood].

Recurrent abdominal pain in childhood can be caused structurally, functionally, metabolically or psychosomatically. In the neonatal period there occur malformations, in infancy chronic inflammations of bowel as well as obstructions due to adhesions following laparotomies or chronic intussusceptions or volvulus. In pre-school and school-age symptoms of appendicitis, lymphadenitis, Crohn's disease or Colitis ulcerosa occur. But every 8th to 9th child of school-age suffers from functional abdominal pain without structural origin, probably caused by an "irritable colon".

Abdomen↗

[Integral intravenous feeding in pediatric surgery].

Forty newborns bearing several gastrointestinal conditions (congenital malformations, intestinal bypass, postinflammatory obstruction, malabsorption and enteritis) were treated with long-term integral parenteral nutrition. A solution made up of synthetic aminoacids, emulsion of lipids, glucose, electrolytes, vitamins, plasma and whole blood was perfused through a catheter introduced into central or peripheral veins. Temporal glucosuria and anemia were observed in some cases. In all but three cases urinary alpha amino nitrogen was normal. In some infected patients leucocytosis or leucopenia was found. After treatment, all patients showed adequate nutritional conditions, manifested by increase in body weight and healing of damaged tissues.

Body Weight↗