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[Long-term comparative anatomic results of retinal detachment with vitreoretinal proliferation operated with or without using liquid perfluorocarbons].

PURPOSE: To investigate whether peroperative perfluorocarbon liquids (PFCL) improve the long term anatomical success of retinal detachment associated with severe proliferative vitreoretinopathy (PVR). PATIENTS AND METHODS: The charts of 62 successive patients operated on for retinal detachment associated with severe PVR were retrospectively analyzed. For one group of 39 patients PFCL were used intraoperatively to improve membrane dissection. The anatomical status of the two groups were compared one month after surgery and at least 6 months after silicone oil ablation. RESULTS: Anatomical success was observed in 84.6% in the group of patients operated with PFCL compared to 52% in the other group (P = 0.005). At the end of the follow up, anatomical success was observed in 64% of patients operated with PFCL compared to 61% in the control group (P = 0.8). However, recurrences were observed later in the group operated on with PFCL. CONCLUSION: Perfluorocarbons liquids significantly improve the initial reattachment of retinal detachment complicated with severe PVR, but they do not seem to improve their final anatomical status.

Adult↗

Primary retinal detachment: scleral buckle or pars plana vitrectomy?

PURPOSE OF REVIEW: There remains no consensus among vitreoretinal surgeons regarding the optimal management of primary rhegmatogenous retinal detachment. In this article, fundamental principles are discussed and applied to recent clinical reports. RECENT FINDINGS: The consensus of the peer-reviewed literature appears to be that scleral buckling and primary pars plana vitrectomy may yield comparable single-operation success rates and visual acuity outcomes for a wide variety of rhegmatogenous retinal detachments. SUMMARY: No definitive prospective, randomized, multicenter trial compares scleral buckling with pars plana vitrectomy. The upcoming Scleral Buckling versus Primary Vitrectomy in Rhegmatogenous Retinal Detachment study may yield useful information in this regard. Even when this study is completed, the choice of surgical modality is complex and may be individualized for specific patients.

Humans↗

Combined phacoemulsification, intraocular lens implantation, and scleral buckling surgery for cataract and retinal detachment.

BACKGROUND AND OBJECTIVE: To evaluate the effects of simultaneous surgery for cataract and retinal detachment. PATIENTS AND METHODS: Six patients with a diagnosis of retinal detachment accompanied by dense cataracts precluding fundus visualization were enrolled in this study. A triple procedure involving phacoemulsification, posterior chamber intraocular lens insertion, and scleral buckling was performed in all six cases. RESULTS: A clear intraoperative view of the fundus was obtained in all cases and retinal breaks were identified in five cases. The retina was successfully reattached in all six cases, five of which showed improvement in visual acuity. CONCLUSION: Combined cataract and scleral buckling surgery can be performed safely. This procedure spares the patient repeat surgery and may improve the visual outcome by clearly identifying the breaks and avoiding delays in detachment repair.

Adult↗

The chemoattractant activity of the vitreous to human scleral fibroblasts following retinal detachment and proliferative vitreoretinopathy.

The results are presented of a migration assay of scleral fibroblasts to 25% diluted vitreous samples from 27 patients with complex retinal detachments divided into three groups: group 1, no proliferative vitreoretinopathy (PVR); group 2, early PVR; and group 3, advanced PVR. There was a statistically significantly greater migration with vitreous samples from group 3 than with group 1 (p less than 0.0001) but no significant correlation for migration with the age of patients, duration of retinal detachment, or number of retinal procedures undertaken. Analysis of vitreous by gel electrophoresis showed that cellular migration was proportional to the number of peptide bands. Vitreous fibronectin levels were measured and there was a positive correlation between fibronectin in the vitreous samples and the migration of fibroblasts to the vitreous (r = 0.68, p less than 0.004).

Adult↗

[Time course of changes in aqueous protein concentration in rhegmatogenous retinal detachment].

Changes in aqueous protein concentration (APC) in unilateral rhegmatogenous retinal detachment (RD) were investigated 1) prospectively in 40 patients who were undergoing scleral buckling surgery with cryotherapy and 2) retrospectively in another 40 patients who had undergone successful retinal reattachment more than 2 years previously. Before the surgery, APC in RD eyes was more than double that in the contralateral normal eyes. The surgical intervention led to a further increase in APC and a peak was observed at 2 weeks postoperatively. Values decreased to a stable level approximately 3 months after surgery, but remained significantly higher than those of the control eyes. Clinical factors which were found to significantly correlate with APC were: 1) before surgery; age, area of RD, balloon-shaped RD, tear rather than hole, and the extent of preoperative hypotony; 2) in the early postoperative period; age, size of retinal breaks, and number of cryoapplication; and 3) in the late postoperative period; age, area of RD, and performance of scleral encircling. It was suggested that different mechanisms are responsible for the increase in APC observed at different periods, including 1) decreased aqueous bulk flow; 2) disruption of the blood-retinal barrier caused by cryotherapy, and/or dispersion of subretinal protein during the surgeries; and 3) decreased aqueous flow rate following buckling procedures, and breakdown of the blood-aqueous barrier induced by changes in anterior uveal blood circulation.

Aqueous Humor↗

[Complications of retinal detachment surgery].

The surgical treatment of the retinal detachment is concerning surgical technics, procedures, devices--both "classics" or from a new modern group, wich may lead sometimes to adverse reactions or complications. Not being always iatrogenic, their risck must be known under all their aspects, in order to addopt a proper and individualized therapy.

Humans↗

Lesions simulating serous detachment of the pigment epithelium. Occurrence after retinal detachment surgery.

Serous detachment of the retinal pigment epithelium (RPE) has been previously described in association with disorders of the underlying choroid and Bruch's membrane but has not been reported after retinal reattachment surgery. We have observed, for at least 16 months, three cases that clinically appeared to be RPE detachments after scleral buckling. In each case the lesions exhibited the typical biomicroscopic features of focal serous detachment of the RPE. However, the failure to show the typical fluorescein pooling has prompted us to regard these lesions as focal pockets of turbid subretinal fluid that simulate RPE detachments.

Aged↗

Results of vitrectomy for diabetic traction retinal detachments using the en bloc excision technique.

En bloc excision is a technique in which fibrovascular diabetic membranes and the posterior hyaloid are separated from the retina as a single unit. In a consecutive series of 69 eyes with diabetic traction retinal detachment treated with this technique, initial retinal reattachment was accomplished in 100% (69/69) of the eyes. With a minimum of 6 months' follow-up, the retina remained completely attached in 83% (57/69) of eyes, while the macula was attached in 88% (61/69) of eyes. Final visual acuity was 5/200 or better in 71% (49/69) of eyes. While current surgical techniques allow a high rate of anatomic success in the repair of diabetic traction retinal detachment, visual results remain limited by irreversible alterations in retinal function.

Adolescent↗

[Pigmentation on the anterior chamber angle in retinal detachment associated with atopic dermatitis].

We reported pigmentation on the anterior chamber angle in twenty-two patients suffering from atopic dermatitis. Dense pigmentation on the anterior chamber angle was observed in all eight eyes with retinal detachment and was evident before clinical recognition of detached retina. Minimal or slight pigmentation was also evident in eyes without retinal detachment. Increased pigmentation on the anterior chamber angle is a characteristic and predictive sign of retinal detachment associated with atopic dermatitis. This pigment appeared to migrate from latent breaks because of inflammation of the peripheral retina and ciliary body.

Adolescent↗