[Massive gastrointestinal hemorrhage].
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Intra-arterial 99mTc colloid scintigraphy may have greater sensitivity than either standard intravenous scintigraphy or selective arteriography in detecting gastrointestinal bleeding. Ten millicuries of 99mTc colloid were administered directly into the superior and inferior mesenteric arteries (SMA and IMA) of patients who had undergone selective arterial catheterization for the evaluation of gastrointestinal bleeding. In one patient, 99mTc-albumin colloid was administered directly into the IMA and identified diverticular bleeding. The bleeding had been occult to prior contrast arteriography and refractory to selective intra-arterial Pitressin therapy. In a second patient who had undergone three negative provocative angiograms, selective SMA injection of 99mTc-sulfur colloid identified occult mesenteric varices secondary to portal hypertension. Selective intra-arterial scintigraphy should be valuable in detecting intestinal bleeding occult to conventional studies. This will help in directing further therapy and diagnostic evaluation.
The Apache II scoring system has been used to identify a clinical status of 10 patients, admitted to the intensive therapy unit with bleeding to gastrointestinal tract during the period 1. January - 30. Juni 1992. There were 9 men and 1 woman with mean age of 61.5 years (37-82). Apache II score was calculated before beginning of treatment and 4 times during following 3 days every 12 or 24 hours. The mean score before beginning of treatment was 9.7 (5-17). All the patients were treated exclusively by the conservative therapy with mean length of hospitalization 8, 1 days (4-12). The score during the therapy has had a decreasing tendency and statistically significant decrease came after 72 hours of treatment. Mortality rate at mentioned values was zero. The use of the Apache II scoring system contributes to improvement of clinical judgment of patients with gastrointestinal bleeding.
A 75-year-old man with angiodysplasia of the sigmoid and rectum and recurrent lower gastrointestinal bleeding episodes, despite repeated endoscopic laser-coagulation, was successfully treated with oestrogen-progesterone. Besides angiodysplasia he had aortic valvular stenosis, monoclonal gammopathy, mild renal insufficiency, and moderate peripheral arteriosclerosis obliterans. Oestrogen-progesterone may be a valuable alternative therapy in elderly patients with repeated bleeding, despite endoscopic coagulation, secondary to gastrointestinal angiodysplasia which cannot be treated surgically, in patients who deny surgery, or with rebleeding after surgery.