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At least 1,351 records · Page 75Linked to original sources

PubMed2005

Plaque removal efficacy of a novel tooth wipe.

OBJECTIVE: This study was designed to evaluate the safety and plaque removal efficacy of a tooth wipe (Oral-B Brush-Ups) using a manual toothbrush as a control. METHODOLOGY: Twenty-five healthy subjects from a general population were enrolled in this randomized, single-use, crossover study. After 23-25 hours of no oral hygiene, oral hard and soft tissues were examined, and disclosed plaque was scored using the Turesky, et al. modification of the Quigley Hein Plaque Index. Subjects used their randomly assigned product for a timed period of one minute without instruction, after which hard and soft tissues and plaque scores were reassessed. Subjects returned to the clinic after a one-week washout period, and the clinical procedures were repeated before and after use of the alternate product. All clinical measurements were made by one examiner who was masked to treatment sequence. RESULTS: Both the tooth wipe and toothbrush were found to be safe, and significantly reduced plaque levels from whole mouth, facial, and lingual surfaces (p < 0.0001). The toothbrush removed significantly greater plaque than the tooth wipe (p < 0.0001) on whole mouth surfaces (49% vs. 29%), facial surfaces (71% vs. 44%), and lingual surfaces (25% vs. 13%). CONCLUSION: The tooth wipe provides an effective method of plaque removal when tooth brushing is not practical.

Adolescent↗

PubMed1990

[Three-dimensional shape measurement of teeth. (6) Measurement of tooth model by tilting method by means of the double sensor laser displacement meter, and the simulation of occlusion].

To measure the three-dimensional shape of the undercut portion of a molar model tooth, the tilting method was used. The measuring system was composed of a laser displacement meter with double sensor and a computer controlled tooth model scanning machine (CAMM-3). A model tooth was tilted on the gonio stage with +/- 20 degrees and measured divisionally, and a couple of data were connected by the TILCOMPO program. The undercut portions from the survey line to the tooth neck were measured and drawn by CG. By this tilting method, the whole shape of tooth including the undercut portion could be measured, and these data will be available for the production of the data base for CAD of prosthesis. The marginal line on the crown abutment measured previously was searched. Initially, the difference in the inclination dz/dx between the data before and behind was calculated, and the gingival line was extracted by limiting its value. Then, also by limiting the difference value, the margin located above the gingival line was determined. Thus the marginal line in contact with the inner and outer crown and a significantly important point for the production of crown by the CAD/CAM technique could be determined around the crown abutment. Another elementary attempt to simulate the occlusion by using the data of teeth models measured on the articulator was carried out. The maxillary and mandibular teeth were set on the articulator and the maxillary teeth turned over. The shapes of the 5-7 upper and lower molar were measured. The two data were connected and occluded by the "OCCLUS" program.(ABSTRACT TRUNCATED AT 250 WORDS)

Computer Simulation↗

PubMed1990

Shark tooth morphogenesis. An SEM and EDX analysis of enameloid and dentin development in various shark species.

The study provides a survey of shark tooth morphogenesis based on SEM and EDX analyses of whole tooth families in six shark species. The teeth, demonstrating different stages of development, were acid-etched and coated with palladium. Calcium content was determined semi-quantitatively by using the palladium coating as an internal standard. Due to the rapid development of the enameloid, all major events took place in the two or three youngest teeth of a tooth family. Enameloid appeared to develop as a transformation of the peripheral part of the dental papilla. Mineralization started immediately. Based on morphological criteria the middle zone of the enameloid was established at an early stage, excluding the possibility of an unambiguous centrifugal or centripetal direction of growth. Substantial mineral increase first occurred in the middle zone, spreading from the tooth tip toward the base. Dentin formed after the enameloid was completely established. Dentin formation started basally as a direct prolongation of the enameloid cap, then spreading toward the tooth tip, first along the edges. It is concluded that shark enameloid has a mesenchymal background, but a role played by the inner dental epithelium can not be excluded.

Amelogenesis↗

PubMed1989

[Changes of the periodontal vascular network, periodontal fiber and alveolar bone incident to tooth extrusion].

During the application of orthodontic force to a tooth, the surrounding tissues undergo changes of bone resorption and apposition, thereby resulting in tooth movement. The purpose of this study was to investigate the interrelationship between alveolar bone changes and the periodontal vascular network caused by extrusive orthodontic force using a scanning electron microscopy. Extrusive orthodontic force was applied to the mandibular 2nd and 3rd premolars of adult dogs. At the completion of the loading process, the inferior alveolar arteries were injected with a low viscosity MMA resin (Mercox). The following results were obtained. 1) At 3 days post-extrusion, various types of vascular network showing a loop pattern were seen along the direction of the tooth movement. 2) At 7 days post-extrusion, various types of vascular network with a hairpin loop pattern along the direction of the tooth movement were observed. Histologically, the fibers of periodontal ligament were stretched in the direction of the extrusion, Vascular hairpin loop formations were observed within the fibers of periodontal ligament. Bone apposition was not observed on the surface of alveolar bone. 3) At 14 days post-extrusion, a much more extensive and developed hairpin loop pattern occurred. Furthermore, new bone apposition was seen on the alveolar bone beneath under the hairpin loops. The periodontal ligament space was retained in the same width, even after bony apposition. 4) At 21 days post-extrusion, the tooth side microvascular network showed abundant low hairpin loops which anastomosed each other, and new spinous bony apposition was observed right below the periodontal vascular network. 5) At 30 days post-extrusion, the periodontal vascular network showed a almost normal appearance, with the rearrangement of vascular network. The surface of the spinous bony apposition became flat. The appositional bone had a lower degree of calcification than the alveolar bone in control group. 6) At 60 days post-extrusion, the periodontal vascular network completed the rearrangement of vasculature.

Alveolar Bone Loss↗

PubMedDate not supplied

Baby bottle tooth decay in Native American children in Head Start centers.

Baby bottle tooth decay is a unique pattern of dental caries (tooth decay) affecting the dentition of young children. It is associated with the practice of putting the child to sleep with a nursing bottle filled with liquid that contains sugar. Practitioners who treat Native American children have noted that this population suffers from a high prevalence of the condition. In order to establish specific program priorities and treatment needs for this segment of the Native American population, additional information is required on both prevalence and severity of baby bottle tooth decay. In this survey, an overall prevalence of 70 percent was observed when Navajo and Cherokee Head Start students ages 4-5 years were examined. Of the children affected by baby bottle tooth decay, 87 percent displayed the most severe manifestation of the disease. The prevalence of this disease in these Native American children appears to be substantially higher than in other populations. Further study is needed to identify the factors contributing to this difference in prevalence and to identify effective measures for reducing the occurrence of baby bottle tooth decay among Native Americans.

Arizona↗

PubMed1989

[The effect of fluoride-containing tooth paste on dental plaque and on fluoride level in the mouth].

Various kinds of fluoride have been used for a long time and there are many reports concerning fluorides and their effects. Recently, the caries-inhibiting action of fluoride-containing tooth paste has been given much attention. In this study, I tried to clarify the residual time and amount of fluoride derived from the fluoride-containing tooth paste in the mouth, as well as to assess possible variation in bacterial composition in the dental plaque bacteriologically and biochemically. In the study on the fluoride clearance from the mouth, both 1.0 g and 0.5 g of paste showed the same reduction rates; and about an 80% reduction was recognized between the value at 3 minutes and that at 30 minutes, and about a 40% reduction from the 30-minute to the 60-minute interval. Next, a study on the variation in plaque bacteria was carried out. The total number of the CFU on each plate was not different between samples obtained before and after the use of the tooth paste; moreover, no difference was noted between aerobic and anaerobic culture. However, when plaque before and after brushing with fluoride-containing tooth paste were cultured in 10% sucrose solution, the differences of acid production such as lactic acid, acetic acid, and formic acid were demonstrated. Namely, these acid productions were inhibited after the use of fluoride, especially lactic acid was strongly inhibited. On the other hand, when Str. mutans from the plaque obtained after the use of fluoride-containing tooth paste was cultured in fluoride-free BHI broth, the inhibition of acid from carbohydrates was not shown clearly.(ABSTRACT TRUNCATED AT 250 WORDS)

Bacteria↗

PubMed1989

Tooth loss in a selected population in Saskatoon.

Tooth mortality in a population can provide information about the prevalence of dental disease, availability of dental care and attitudes about tooth extraction. The tooth mortality of patients presenting for treatment at the University Dental Clinic (Saskatoon, Canada) during the school terms 1981-1986 was determined to provide base-line data during a time when the dentist-to-population ratio has been increasing, and to compare the results with similar studies carried out in Britain and Greece. The data were analyzed according to the same quinquennial age groups as in the other studies. There were no statistically significant differences between the two time periods at all ages and therefore the data were pooled. Totally edentulous persons were excluded from the analysis for comparison purposes. The prevalence of tooth loss increased with age with a rapid period of tooth loss encompassing the mean ages of 34 to 47 years, a slowing of further loss up to the mean age of 62 and thereafter, a further increase. The initial rapid loss was most apparent for molar teeth and least apparent for mandibular incisor teeth. With the exception of first molars, more teeth were lost in the maxilla than in the mandible. The present data are similar to the findings reported in British and Greek studies.

Adolescent↗

PubMed1984

The use of electron spin resonance on human tooth enamel in relation to caries-susceptibility.

By means of the electron spin resonance technique it is possible to detect carbonate-related paramagnetic centers in human tooth enamel. Several arguments indicate that the radical formed after X-ray irradiation is a CO2- rather than a CO(3)3- center. There is experimental evidence that the distribution of the orientation of those centers is related to caries-susceptibility, but care has to be taken with regard to the interpretation of the results formulated in the literature. In our own preliminary research, we have studied the ESR-spectra of both bovine and human tooth enamel. As a model for human tooth enamel, the study of bovine enamel was unsatisfactory, because the signals were visibly different from the ones obtained on human tooth enamel. The reproducibility of the ESR-signals in human tooth enamel was carefully studied and found to be excellent. We also investigated the effect of heating these samples, and noted a drastic change in the spectra. Our numerical values for the R-parameter, as introduced by Cevc et al. (1976, 1980), are considerably lower than the ones they published. Clearly, additional information concerning the sample-preparation-technique and the etiological factors which determine the R-value, should be gathered.

Carbonates↗

PubMed2005

Tooth transplantations: a descriptive retrospective study.

The aim of the present study was to perform a retrospective study of autogeneously transplanted teeth in order to examine the influence of clinical criteria such as the type of the donor tooth, the root length at the time of transplantation, donor eruption stage and others on the overall success rate of the transplantation. The material of this study consisted of 194 patients in whom 273 teeth were transplanted. The mean age at the time of autotransplantation was 18.1 years with a standard deviation of 7.5 years. Transplantations were performed in two hospitals. The follow-up period varied from 15 days to 11 years, and the mean follow-up time was 3.8 years. 58/273 teeth showed one or other form of resorption, 37/273 teeth showed ankylosis, 30/273 showed no important changes in pulp chamber size, 104/273 showed major discoloration after transplantation, 92/273 teeth showed positive results for cold test after transplantation and 26/273 teeth showed clinically unacceptable pocket depth. Clinical and radiological evaluations were performed. An association was found between successful transplantation and donor tooth type (P<0.01), root length at the time of transplantation (P<0.0001) and recipient tooth site (P=0.03). There was a borderline association between successful transplantation and donor eruption stage (P=0.05). In conclusion, autotransplantation of teeth performed with a careful surgical procedure at the stage of 1/2-3/4 of their intended or expected root length can render a very useful service to patients.

Adolescent↗

PubMed1998

Longitudinal analysis of deciduous tooth emergence: II. Parametric survival analysis in Bangladeshi, Guatemalan, Japanese, and Javanese children.

We present a form of parametric survival analysis that incorporates exact, interval-censored, and right-censored times to deciduous tooth emergence. The method is an extension of common cross-sectional procedures such as logit and probit analysis, so that data arising from mixed longitudinal and cross-sectional studies can be properly combined. We extended the method to incorporate and estimate a proportion of agenic teeth. While we concentrate on deciduous tooth emergence, the method is relevant to studies of permanent tooth emergence and other developmental events. Deciduous tooth emergence data were analyzed from four longitudinal studies. The samples are 1,271 rural Guatemalan children examined every three months up to age two and every six months thereafter as part of the INCAP study; 397 rural Bangladeshi children examined monthly to age one and quarterly thereafter as part of the Meheran Growth and Development Study; 468 rural Indonesian children examined monthly as part of the Ngaglik study; and 114 urban Japanese children examined monthly in studies from 1910 and 1920. Although all four studies were longitudinal, many observations from the Guatemala and Bangladesh studies were effectively cross-sectionally observed. Three different parametric forms were used to model the eruption process: a normal distribution, a lognormal distribution, and a lognormal distribution with age shifted to shortly after conception. All three distributions produced reliable estimates of central tendencies, but the shifted lognormal distribution produced the best overall estimates of shape (variance) parameters. Estimates of emergence were compared to other studies that used similar methods. Japanese children showed relatively fast emergence times for all teeth. Bangladeshi and Javanese children showed emergence times that were slower than are found in most previous studies. Estimates of agenesis were not significantly different from zero for most teeth. One or two central incisors showed significant agenesis that ranged from 0.1 to 0.8% in three of the samples; even so, failure to model the agenic proportion did not seriously bias the estimates.

Bangladesh↗

PubMed1977

Regional variation in tooth size and pathology in fossil hominids.

Tooth size and dental pathology in fossil hominids were studied to test for regional differences in these parameters. The results showed little regional variation in tooth size for the Middle and Upper Pleistocene sites compared (except for Krapina) but considerable differences in the severity of attrition and dental pathology. These differences were considered indicative of regional differences in the functional load borne by the teeth, and in view of the similar technological status of the groups studied, were attributed to environmental differences in the diet. Since, in all regions, reduction in tooth size appeared to continue at the same rate for the periods investigated, no association can be established between presumed selective pressures related to differences in functional demands made on the dentition, and tooth reduction.

Adult↗

PubMed1994

Translocation of enamel proteins from inner enamel epithelia to odontoblasts during mouse tooth development.

The developmental problem of how dental epithelia and/or dental papilla ectomesenchyme induce and/or up- or down-regulate tooth formation are as yet unresolved issues. We have designed studies to map the synthesis and fate pathways of secreted amelogenin proteins from Kallenbach differentiation zones II-IV during in vivo and in vitro mouse mandibular first molar tooth development (M1). Tooth organs from cap, bell, and crown stages were processed for reverse transcriptase/polymerase chain reaction (RT-PCR) and high resolution Protein A immunocytochemistry using anti-amelogenin and anti-peptide antibodies. Cap stage M1 were cultured for periods ranging from 10-21 days in vitro using either serum-less, or 15% fetal calf sera-supplemented, chemically-defined medium. Amelogenin transcripts are expressed in the mouse embryonic molar from E15 through early postnatal development. Amelogenin antigens were first detected in Kallenbach's differentiation zone II. Amelogenin proteins secreted from preameloblasts were identified along cell processes and cell surfaces of odontoblasts adjacent to forming mantle dentine extracellular matrix (ECM) prior to biomineralization. Amelogenin proteins were restricted to forming endocytotic vesicles, clathrin-coated vesicles, and lysosomes within odontoblasts. At later stages (e.g. 2 days postnatal development), enamel proteins were not identified in odontoblasts or predentine matrix following mineralization. Comparable observations for stages of development were noted for in vitro cultured tooth explants. Preameloblasts synthesize and secrete amelogenin proteins which bind to odontoblast cell surfaces possibly through the process of receptor-mediated endocytosis. We conclude that amelogenin proteins secreted from preameloblasts, prior to the initiation of biomineralization, were translocated to odontoblasts to serve as yet unknown biological functions.

Amelogenin↗

PubMed2005

Evaluation of transversal slice imaging in the diagnosis of tooth displacement with special consideration of the upper canines.

AIM: The exact localization and analysis of displaced, retained or impacted teeth can rarely be achieved by common radiologic methods providing eccentric or occlusal images. The aim of this study was to evaluate transversal slice imaging (TSI) as a diagnostic alternative, keeping radiation exposure under consideration. MATERIAL AND METHODS: In a pilot study, we simulated seven different canine positions in a phantom head. Each tooth position was visualized by transversal slice imaging and compared by several observers independently and blinded to computer tomography (CT) serving as the gold standard. The clinical study included the retrospective analysis of TSI samples from 27 patients (mean age 13.7 yrs.) according to these criteria: 1. location of the canine crown and root, 2. recognition of the crown, 3. stage of root development, 4. root dilaceration, 5. periodontal ligament space, 6. ankylosis, 7. relationship to neighboring teeth, and 8. resorptions of neighboring teeth. The evaluations of canine position were compared to the results gained intraoperatively. RESULTS: In the transversal slice images taken from a phantom head, the observers' estimations of the canine position were identical in five cases (71.4%). At least four observers using TSI described identical tooth positions in 89% of patients. In 2.5%, no statement concerning tooth position was feasible. Crown recognition was possible in 75% of cases. Ankylosis, periodontal ligament space, root development, dilacerations and resorptions were not assessable in the majority of the cases. CONCLUSION: Transversal slice imaging can be recommended as a second plane projection in diagnosing tooth displacement, especially concerning oro-vestibular localization (effective radiation dose 0.003-0.012 mSv). However, as far as periodontal ligament space, resorptions and root morphology are concerned, this method has its limits.

Adolescent↗

PubMed1993

In vivo and in vitro study of the effects of chlorpromazine on tooth mineralization in rats and mice.

The effects of chlorpromazine (CPZ) on tooth mineralization were examined using incisor dentine in adult rats and cultured tooth germs of mandibular first molars dissected from mouse embryos. CPZ (10, 50 and 250 mg/kg, s.c.) substantially inhibited dentine mineralization as evaluated by contact microradiographs. Plasma calcium and phosphorus concentrations were not decreased by CPZ (10 and 50 mg/kg). Physicochemical effects were not involved in the action of CPZ on the mineralization. In vitro experiments showed that CPZ (1 and 10 microM) inhibited mineralization and alkaline phosphatase (ALP) activity in the tooth germs. As CPZ has the properties of a calmodulin antagonist, the calmodulin antagonists W-7 and W-5 were also examined. Both inhibited mineralization and ALP activity in tooth germs; W-5 had less effect than W-7. These in vivo and in vitro findings suggest that CPZ inhibited cell-mediated mineralization in dentine without affecting the calcium-regulating system and physicochemical mineral deposition. In addition, calmodulin could be involved in cell-mediated mineralization.

Alkaline Phosphatase↗

PubMed1994

Dynamic variations in the expression of type I collagen and its molecular chaperone Hsp47 in cells of the mouse dental follicle during tooth eruption.

Tooth eruption is a precisely timed and sequenced event that brings the tooth from within bone into a functional position in the mouth. Every part of the developing tooth has been theoretically implicated as a primary factor in this process, but it now appears that eruption is multifactorial, with the dental follicle and type I collagen playing an important part. Immunological probes were used here to investigate in vivo and in vitro the temporal and spatial expression of type I collagen and its molecular chaperone Hsp47 in the dental follicle during eruption. Mandibles were dissected from 2-, 5-, 9- and 11-day-old neonatal mice and fixed in 95% ethanol overnight. Sections of 7 microns were obtained and reacted with antibodies directed against type I collagen. Dental follicles were isolated from 2-, 5-, 9- and 11-day-old neonates and cells were grown in culture for 8 days. Slides were then reacted with antibodies directed against type I collagen and Hsp47. The production of type I collagen and Hsp47 in the follicle varied with the stage of dental development and eruption. There was a progressive decrease of type I collagen in the coronal part of the follicle, leading to an arrest of its production in these areas. These findings support the notion that cells of the coronal portion of the dental follicle stop producing type I collagen as a prerequisite to the initiation of tooth eruption and that this phenotype persists in vitro.

Animals↗

PubMed1996

Development and cell fate in interspecific (Mus musculus/Mus caroli) intraocular transplants of mouse molar tooth-germ tissues detected by in situ hybridization.

Mandibular first molar tooth germs were dissected from Mus musculus (CDI) and Mus caroli (age range: 14-day embryo to 1-day postnatal). Most of the tooth germs were separated enzymically into epithelial and mesenchymal components. Interspecific tissue recombinations and intact M. caroli tooth germs were grown in the anterior chamber of the eye of adult CDI mice for 24 weeks. Recombinations of M. caroli enamel-organ epithelium with M. musculus, dental papilla and follicle mesenchyme developed into normal teeth with advanced root, periodontal ligament and bone formation, thereby confirming extensive epithelial-mesenchymal interactions across the species barrier. Labelling sections by in situ hybridization with a M. musculus-specific DNA probe (pMSat5) showed that almost all cells in the pulp, periodontal ligament and bone were M. musculus, including cementoblasts. Reduced enamel epithelium and epithelial cell rests derived from donor M. caroli enamel organ were unlabelled. This indicates that any cementogenic role of Hertwig's epithelial root sheath must be short-lived. The immunological privilege of the intraocular transplantation site in M. musculus CDI mice did not extend to grafts including xenogeneic M. caroli dental mesenchyme. Thus, intact M. caroli tooth germs and recombinations of M. musculus enamel organ with M. caroli dental papilla and follicle showed limited development, with no root formation, and were populated almost exclusively with labelled host M. musculus lymphocytes.

Alveolar Process↗

PubMed1995

Assessment of tooth wear in an ageing population.

A random sample of 2222 adults aged 45 years and over was taken from the age/sex registers of two general medical practices in Newcastle upon Tyne, and asked to take part in a dental health survey. A total of 1002 individuals agreed to take part and were visited in their homes. Five hundred and eighty-six subjects were dentate and able to undergo an assessment of tooth wear using the Tooth Wear Index (TWI). Increasing wear with increasing age was observed for all cervical and occlusal/incisal tooth surfaces. Occlusal/incisal surfaces displayed some of the highest mean wear scores, especially in the older age cohorts. With the exception of lingual surfaces of maxillary anterior teeth, no significant variation in tooth wear with age was noted for buccal or lingual surfaces. Greater mean wear scores were observed among males than females, but there was little variation between subjects of different social class backgrounds. The threshold levels of wear suggested for use with the TWI may require modification for use among elderly populations.

Age Factors↗

PubMed1986

Autotransplantation of cryopreserved tooth in connection with orthodontic treatment.

In orthodontic treatment of certain cases of tooth loss, aplasia, or ectopia, autotransplantation is sometimes a valid treatment alternative and often provides an improved result, compared to conventional orthodontic treatment, if an appropriate donor tooth is available and the anatomic circumstances permit it. However, in some cases autotransplantation is not immediately possible as a one-step procedure. In such cases cryopreservation provides a clinically useful technique when an extraoral storage period of months or years is needed to orthodontically prepare the recipient region. In the present case a mature upper first left premolar was stored for 18 months. During this period sufficient space was achieved in the contralateral recipient region between the upper left first and second premolars. The thawed graft was autotransplanted to this position. Endodontic treatment was initiated 4 weeks after transplantation. Four years after transplantation, the periodontal healing of the grafted tooth appeared clinically and radiographically normal without any signs of root resorption. The presented case demonstrates the capacity of a cryopreserved tooth to regenerate what seems to be a normal periodontium after transplantation. If these findings are confirmed in further clinical trials, the technique could be a valuable tool in future orthodontic treatment planning.

Adult↗