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At least 1,369 records · Page 76Linked to original sources
PubMed1983

Effect of oral dosing of Lactobacillus strains on gut colonization and liver biotin in broiler chicks.

Strains of host specific (KTM, 74/1, and 59) and nonhost specific (40) lactobacilli were orally dosed to day-old broiler chicks. Dose levels consisted of: 5.0, 7.0, and 9.0 log10 cfu/day for 21 days. Each treatment and control group (placebo, no culture) contained three replications of 6 chicks in Experiment 1 (strains 40 and KTM) and 7 chicks in Experiment 2 (strains 74/1 and 59). Dosing of 7.0 log10 cfu and above tended to depress chick growth. Fecal shedding of lactobacilli were the same (8.8 log10 cfu) for all dose levels on Day 5 but decreased on Day 14 for strains KTM and 40. For strains 74/1 and 59 at all dose levels, the fecal shedding of lactobacilli was 9.9 log10 cfu for Day 5 and 8.5 log10 cfu for Day 14. Microbiology was performed on contents of the crop and ileum and on the tissue macerates from the crop, ileum, and ceca from chicks killed on Days 7 and 21 of the experiments. Chicks dosed with strains 59 and KTM had lower numbers of coliforms in cecal macerates than the control and chicks dosed with strains 40 and 74/1. No significant differences were observed in lactobacilli found in contents and tissues between 5.0 and 9.0 log10 cfu for all lactobacilli strains dosed. There was a trend for the liver biotin to be higher in chicks dosed with 7.0 log10 cfu than chicks dosed with 5.0 or 9.0 log10 cfu or no culture, but the difference was not significant (P greater than .05).

Animals↗
PubMedDate not supplied

Control of intestinal flora in animals and humans: implications for toxicology and health.

The importance of the intestinal flora in disease management is discussed, and apparent relationships noted in experimental and clinical reports are reviewed. It is suggested that investigation of the influence of the intestinal flora upon body organs and systems would productively lay the groundwork for abetter understanding of certain synergistic mechanisms.

Animals↗
PubMed1999

D-lactic acidosis in short bowel syndrome.

Short bowel syndrome can present many complex management issues and may be complicated by various metabolic problems. D-lactic acidosis in the setting of short bowel syndrome has been described only rarely in children. A further case is presented with a review of typical clinical manifestations of D-lactic acidosis and reported management options. Early recognition and appropriate management is essential to avoid morbidity secondary to this complication of short bowel syndrome. Probiotic therapies may have an increasing role in prevention and management of this complication.

Acidosis, Lactic↗
PubMed2000

[The antagonistic activity of the eubiotic Maxilin towards wound infection and its effect on the antibiotic resistance of microorganisms].

Antagonistic activity of lactic acid bacteria of strain N 2585 of "Maxilin" probiotic in respect to the strains S. aureus, P. aeruginosa, E. coli, Candida albicans and their effect on the level of sustainability of the antibiotic resistant strains S. aureus, E. coli, P. aeruginosa, which are extracted from the patients with open fractures of the mandible under various course of wound process, have been studied. The studies showed that lactic acid bacteria have suppressed growth of strains Candida most actively, followed by P. aeruginosa, S. aureus and E. coli. The use of "Maxilin" probiotic allowed reducing the epidemiological significance of pathogenetic strains already in 3 to 4 days. The sensibility studies showed high activity of the lactic acid bacteria in reducing antibiotic resistance of the strains investigated. It was revealed that "Maxilin" probiotic affects Ps. aeruginosa effectively, somewhat less St. aureus and E. coli. The extracted strains demonstrated sensibility to all investigated antibiotics already in 3 to 4 days.

Anti-Bacterial Agents↗
PubMed2001

[Microecological system and its importance in evaluation of the effectiveness of biologically active supplements and probiotic products].

A possibility to estimate a quality of bioactive supplements and probiotical foods by their influence on microecological system of a gastrointestinal tract are exhibited as a result of multiyear research. The consist and biological activity of micropopulations, including the normalization of level of protective intestinal microflora, the increasing their antibiosis activity, the elimination of potentially pathogenic microorganisms, the excretion of volatile phenols and indican with urine, the content of volatile fatty acids, enzymes, secretory immunoglobulins in feces, destruction in vitro cholic acid and cholesterol etc., are tested as indicators. The reasoned supposal is advanced that the wide spread of disbacteriosis is connected not only with changing of defence mechanisms (reactions) of macroorganism, but also with accumulation of pathogenic features in microorganisms by action of environmental factors.

Bacteria↗
PubMed2000

Anti-carcinogenicity of probiotics and prebiotics.

Yoghurt, and the lactic acid producing bacteria (LAB; probiotics) that it contains, have received much attention as potential cancer-preventing agents in the diet. It is usually considered that the mechanism of the action is by increasing the numbers of LAB in the colon, which modifies the ability of the microflora to produce carcinogens. Prebiotics such as non-digestible oligosaccharides (NDO) appear to have similar effects on the microflora by selectively stimulating the growth of LAB in the colon. Evidence for cancer-preventing properties of pro- and prebiotics is derived from studies on faecal enzyme activities in animals and humans, inhibition of genotoxicity of known carcinogens in vitro and In vivo, suppression of carcinogen-induced preneoplastic lesions and tumours in laboratory animals. Some of these studies indicate that combinations of pro and prebiotics ('synbiotics') are more effective. Epidemiological and intervention studies provide some, albelt limited, evidence for protective effects of products containing probiotics in humans.

Animals↗
PubMed2002

[Use of probiotics Bifidumbacterin and Acilact in tablets in therapy of periodontal inflammations].

The results of the use of russian probiotics Acilact and Bifidumbacterin in complex treatment of gingivitis and different degrees of parodontitis are presented. The treatment of the patients of control group was added by the italien drug Tantum Verde. The effect of Acilact and Bifidumbacterin to the normalisation of Mycroflora higher in comparison with Tantum-Verde, particulary in the cases of gingivitis and parodontitis superficialis.

Anti-Infective Agents↗