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PubMed1984

Correspondence between attitudes and drinking and drug behavior: youth subculture over time.

In a longitudinal study, the researcher utilized both nonparticipant observational data and quantified interview data to analyze the correspondence between attitudes of the "youth subculture" theories and overt behavioral patterns. The data were collected in an upper-middle-class, predominantly white, Southern California beach community. An initial cohort of 23 males was followed from 1971 through 1981. A separate sample of males, aged 14 to 21, was observed from the summer of 1975 through December, 1981. All subjects were interviewed at the close of the project. The interview schedule included items regarding drug use, sexual activity, employment, and school patterns as well as attitudes reflective of pleasure-seeking and deferred gratification. Subjects are classified according to degree of drug use and analyzed according to several other variables. It is found that the older cohort, analyzed qualitatively, fit the theoretical implications of the model involved both as to attitudes and behavior. However, with the end of the Vietnam War and an increased influence of the "Jesus Movement," this group did become slightly more conservative in attitudes regarding politics and religion. The heavier drug users in the later sample are similar in behavior patterns to the older cohort. However, the more recent group of heavy users express extremely conservative views regarding morality, religion and politics. Specific attitudinal measures indicate no relationship between degree of drug use and youth subculture attitudes. The attitudes measured regarding pursuit of pleasure and immediate gratification did not appear to be consistent with actual overt behavior.

Adolescent↗

PubMed2001

Drinking in adulthood: similarities and differences in effects of adult roles for Hispanic ethnic groups and Anglos.

OBJECTIVE: This study examines whether the adult social roles perspective. an approach that explains drinking behaviors for Anglos, similarly affects alcohol use by Cubans, Mexican Americans, Puerto Ricans and Other Hispanics (Central and South Americans). METHOD: The 1993 National Household Survey on Drug Abuse, a national probability sample of the household population in the United States, is used. The sample utilized here (N= 13,822; 56.2% female) consisted of 9,388 Anglos, 611 Cubans, 2,459 Mexican Americans, 611 Puerto Ricans and 753 Central/South Americans age 18 and older. The outcome measures include past-year drinking, and for drinkers, heavy drinking and alcohol-related problems. Logistic regression analyses are conducted using Stata. RESULTS: The results show that there are some ethnic differences in the effects of the adult social roles. Of particular importance is the finding that being married has anomalous effects for Cubans (heavy drinking), Mexican Americans (problems) and Other Hispanics (problems) compared with Anglos and the other Hispanic ethnic groups. CONCLUSIONS: The adult social roles perspective has some utility for explaining Hispanic drinking patterns. Future research should consider not only traditional predictors of drinking but also such socio-cultural factors as acculturation and familism, to better understand adult alcohol use by members of Hispanic ethnic groups.

Adolescent↗

PubMed1980

Situational context and the meaning of drinking.

Since most drinking takes place within a social context, a study was designed in which the described situational context of drinking could be systematically varied on the basis of three at least potentially basic contextual characteristics: type of activity or situation, presence of others, and mood. All three variables were found to have strong effects on reactions to or perceptions of drinking as measured by a set of 20 semantic differential scales. Of most importance were the interaction effects which clearly supported the assertion that drinking behavior if a function of culturally structured contexts--that it is learned and situation-specific. Not only did fine distinctions occur in evaluative reactions (including normative expectations) to the various contexts, but perceptions of the effects or impact of alcohol were related to situational context. Furthermore, the appropriateness of focusing exclusively on either the individual drinker or the situational context was addressed. Both sorts of variables were involved in this study, and they were found to interact in affecting reactions to drinking. Situational context, then, is a function not only of contextual variables but also of the persons involved in the situation.

Adult↗

PubMed1975

Duration of hospitalization for alcoholism.

On admission to an inpatient alcoholic treatment center, 58 alcoholic men were randomly assigned to two groups. One group was detoxified and after-care services were planned (mean length of stay nine days). The other group, in a-dition to the above, received intensive psychosocial inhospital treatment (mean length of stay 30 days). Posthospital adjustment was measured at five intervals over a 13 month period in the areas of social relationships, financial status, employment record, legal involvement, drinking behavior, use of measures were obtained on psychological change and counseling readiness. No significant difference was found between the two groups on any measure. These results indicate that the hospital has a limited role in the treatment of the alcholic person.

Adaptation, Psychological↗

PubMed1985

Reinforcement expectancies and alcoholism treatment outcome after a one-year follow-up.

The relationship of alcohol-related expectancies with the drinking behavior and treatment compliance of alcoholics was examined 1 year posttreatment, along with the utility of reinforcement expectancy as a predictor of alcoholism treatment outcome. Of the original sample of 42 men veteran inpatients from an alcoholism treatment program, 81% were interviewed 1 year after treatment. Prediction variables identified in the multiple-regression analyses accounted for 40-57% of the criterion variance. It was found that more limited expectancies of alcohol-produced relaxation were associated with abstinence, as well as nonproblematic drinking. It was also found that there was a consistent negative linear relationship between alcohol expectancies and measures of treatment success.

Aftercare↗

PubMedDate not supplied

Esophageal cancer risk by ALDH2 and ADH2 polymorphisms and alcohol consumption: exploration of gene-environment and gene-gene interactions.

Alcohol drinking is a major risk factor for esophageal cancer in Japan and its impact may be modulated by levels of ALDH2, ADH2 and CYP2E1, three representative alcohol-metabolizing enzymes which display genetic polymorphisms altering individual alcohol-oxidizing capacity and drinking behavior. To assess the actual influence of ADH2 Arg47His, ALDH2 Glu487Lys and CYP2E1 variant c2 allele polymorphisms on esophageal cancer risk with conjunction with alcoholic consumption, the present 1:3 matched case-control study was conducted. The 165 histologically diagnosed Japanese esophageal cancer cases were here compared with 495 randomly selected controls, matched with respect to sex and age. Conditional logistic regression was used to calculated Odds Ratios (ORs) and 95% confidence intervals (95% CI). Significant gene-environment interactions between alcohol drinking and both ADH2 and ALDH2 were observed regarding esophageal cancer risk. The ADH2 Arg47His polymorphism showed moderately increased risk (OR for Arg/His and Arg/Arg relative to His/His: 2.01 (1.39-2.90)). In the ALDH2 case, comparing the Glu/Lys with the Glu/Glu genotype, ORs were markedly increased to 9.64 (3.23-28.8) and 95.4 (28.7-317) from 1.88 (0.42-8.37) and 4.62 (0.93-23.1) for moderate drinking and heavy drinking, respectively. No significant alteration in risk was observed with the CYP2E1 polymorphism. In conclusion, the present study revealed a significant gene-environment interaction between alcohol drinking and the ALDH2 polymorphism regarding esophageal cancer risk among a general population in Japan, providing concrete evidence of a role for acetaldehyde in neoplastic development. Interactions between ALDH2 and ADH2 need further clarification.

Aged↗

PubMed2005

Examining the effects of fatal vision goggles on changing attitudes and behaviors related to drinking and driving.

This study investigated the effectiveness of the Fatal Vision goggles. College students (N = 251) were randomly assigned to one of four groups including two control groups, a group wearing the goggles, and a group watching those wearing the goggles. Attitudes and behaviors toward drinking and driving were assessed immediately prior to and after the intervention, and then again at a four-week follow up. The group wearing the goggles reported significantly greater declines in accepting attitudes toward drinking and driving compared to the other groups at the immediate post-test. However, these differences disappeared after four weeks. Also, the change in attitude was not accompanied by a similar decrease in drunk driving behaviors. Editors Strategic Implications: School and agency administrators, seeking to reduce unacceptably high rates of drinking and driving, will benefit from this well-designed longitudinal experiment. Replication will be necessary, but the authors present strong evidence that this is a prevention strategy that does not result in behavioral change.

Accidents, Traffic↗

PubMed2004

Following alcohol consumption, nontreatment-seeking alcoholics report greater stimulation but similar sedation compared with social drinkers.

OBJECTIVE: Drinking behavior, and consequently the risk to develop alcohol problems, is influenced in part by one's subjective response to alcohol. Studies have shown that individuals at risk for alcoholism report greater stimulation, less sedation and/or "low response" to alcohol. Whether this effect exists in early-stage alcoholics has not been examined. The present study was conducted to determine whether alcoholics and social drinkers differ in response following a challenge dose of alcohol in a clinical laboratory procedure. METHOD: Nontreatment-seeking alcoholics (n = 38) and social drinkers (n = 30) randomized to a placebo in a medication study were given a standard dose of alcohol (0.34 g/kg women; 0.4 g/kg men) in a bar-laboratory setting. Assessments, including blood alcohol concentrations and the Biphasic Alcohol Effects Scale, were conducted four times (from 10 to 60 minutes following initiation of consumption). RESULTS: Alcoholics reported greater stimulation, but similar sedation, compared with social drinkers, following alcohol consumption. CONCLUSIONS: This study provides the first evidence of greater stimulation following alcohol in alcoholics not seeking treatment.

Adult↗

PubMed1984

The subfornical organ and the integration of multiple factors in thirst.

Rats with lesions centered on the ventral stalk of the subfornical organ (SFO) were used to characterize the participation of this structure in the control of drinking. It is concluded that the SFO does indeed play some minor role in the mediation of drinking following intraventricular injections of angiotensin. Further, it is shown that lesions of the SFO, but not lesions of the adjacent septal-hippocampal tissue, attenuate osmotic thirst elicited by two doses of hypertonic saline. Diminished drinking responses following water deprivation, and normal feeding responses following food deprivation, underscore the importance of the SFO for drinking behavior in general, and an expanded role for the SFO in fluid regulation is suggested. However, some incidental observations suggest that the SFO is less than an equal partner with structures in the AV3V region in the overall control of water balance.

Angiotensin II↗

PubMed1996

Predicting underage drinking and driving behaviors.

A social-psychological model of underage drinking and driving (DUI) and riding with drinking drivers (RWDD) was tested with data from a random digit dial telephone survey of 706 16-20-year-old drivers from seven western states in the United States. Consistent with the model, a structural equations analysis indicated that DUI and RWDD were primarily predicted by (a) expectancies regarding the physical risks of DUI, (b) normative beliefs about the extent to which friends would disapprove of DUI, (c) control beliefs about the ease or difficulty of avoiding DUI and RWDD and (d) drinking. Expectancies concerning enforcement had a significant effect on RWDD, but not on DUI. Among the background and environmental variables included in the analysis, only night-time driving and age had significant direct effects on DUI and RWDD. Drinking and involvement in risky driving had indirect effects on DUI and RWDD that were mediated through expectancies and normative beliefs. Males, European Americans, Latinos, respondents who drove more frequently and respondents who were less educated held beliefs that were more favorable toward DUI and RWDD, drank more and engaged more frequently in risky driving. As a result, such individuals may be at greater risk for DUI and RWDD.

Adolescent↗

PubMed2006

Single question about drunkenness to detect college students at risk for injury.

OBJECTIVES: To examine the frequency of injuries reported by college students who replied affirmatively to the question, "In a typical week, how many days do you get drunk?" METHODS: In Fall 2003, a Web-based survey was administered to a stratified random sample of 3,909 college students from ten North Carolina (NC) universities. Students answered questions regarding alcohol use and its consequences. Data were analyzed using multiple logistic regression, controlling for within-school clustering of drinking behaviors and adjusting for other significant covariates. Adjusted odds ratios (AORs) and 95% confidence intervals (CI) were calculated for significant predictors (p < 0.05). RESULTS: Two thousand four hundred eighty-eight students reported that they are current drinkers; 1,353 (54.4%) reported getting drunk at least once in a typical week. Compared with students who did not report getting drunk at least once a week, these students had higher odds of being hurt or injured at least once as a result of their own drinking (AOR = 4.97; 95% CI = 3.47 to 7.09), experiencing a fall from a height that required medical treatment (AOR = 2.16; 95% CI = 1.36 to 3.43), and being taken advantage of sexually as a result of another's drinking (AOR = 2.59; 95% CI = 1.72 to 3.89). Students who reported getting drunk at least one day in a typical week also were more likely to cause an injury requiring medical treatment to someone else. They had higher odds of causing injury in an automobile crash (AOR = 1.84; 95% CI = 1.01 to 3.40), of causing a burn that required medical treatment (AOR = 2.85; 95% CI = 1.51 to 5.39), and of causing a fall from a height that required medical treatment (AOR = 2.02; 95% CI = 1.01 to 4.04). Getting drunk was a better indicator of "self-experienced injury" and of "injury caused to someone else" than was binge drinking, for all outcomes (p < 0.05). CONCLUSIONS: The single question, "In a typical week, how many days do you get drunk?" identifies college students who are at higher than normal risk of injury as a result of their own drinking and the drinking of others. Future research should assess this question's effectiveness as a screening tool in campus health centers and in emergency departments.

Accidental Falls↗

PubMed2006

[Water supply for Peking ducks--possible alternatives for bathing].

In order to investigate possible advantages of open water drinkers such as troughs and bells in the intensive husbandry of ducks, we evaluated in this study the effect of open water systems on the behavior and health of peking ducks. In this investigation six fattening trials each with 1152 Cherry Valley Peking ducks were analyzed. The average fattening period was 47 to 49 days. The ducks were kept on straw in six standardized compartments each 32 qm with 192 ducks. 25% of the compartment with perforated grid, with one of the tested water systems. In contrast to pens with nipple-drinkers only, the ducks in pens with open water troughs/showers had the opportunity to exhibit their natural drinking behavior and water associated activities in accordance with the animal welfare requirements. In the free-choice pens the open water systems were significantly preferred, and over a 24-hour period the ducks in watering areas with open water troughs showed higher activity. Limiting the access to the open water systems to eight, four or two hours per day led to an increased use per time unit. Ducks with access to nipple drinkers only showed a significantly higher percentage of plugged up nostrils than animals from pens with open water drinkers. Open water drinkers had also a positive impact on the plumage condition.

Animal Husbandry↗

PubMedDate not supplied

Biochemical basis of alcoholism: statements and hypotheses of present research.

Experimental results and theoretical considerations on the biology of alcoholism are devoted to the following topics: genetically determined differences in metabolic tolerance; participation of the alternative alcohol metabolizing systems in chronic alcohol intake; genetically determined differences in functional tolerance of the CNS to the hypnotic effect of alcohol; cross tolerance between alcohol and centrally active drugs; dissociation of tolerance and cross tolerance from physical dependence; permanent effect of uncontrolled drinking behavior induced by alkaloid metabolites in the CNS; genetically determined alterations in the function of opiate receptors; and genetic predisposition to addiction due to innate endorphin deficiency. For the purpose of introducing the most important research teams and their main work, statements from selected publications of individual groups have been classified as to subject matter and summarized. Although the number for summary-quotations had to be restricted, the criterion for selection was the relevance to the etiology of alcoholism rather than consequences of alcohol drinking.

Acetaldehyde↗

PubMed1977

Effect of preoptic administration of angiotensin on lateral hypothalamic unit activity.

The effect of administering angiotensin II to the preoptic region on lateral hypothalamic single unit activity was studied in unanesthetized, freely-moving rats. Angiotensin (100 ng) reliably initiated drinking behavior and caused an increase in the discharge frequency of single neurons located in the perifornical area but had no effect on units in the zona incerta, ventromedial hypothalamus or farlateral hypothalamus. These results suggest that efferent pathways from preoptic receptors for angiotensin pass through the midlateral hypothalamus.

Action Potentials↗

PubMed2004

Oral topiramate reduces the consequences of drinking and improves the quality of life of alcohol-dependent individuals: a randomized controlled trial.

BACKGROUND: Topiramate, a fructopyranose derivative, was superior to placebo at improving the drinking outcomes of alcohol-dependent individuals. OBJECTIVES: To determine whether topiramate, compared with placebo, improves psychosocial functioning in alcohol-dependent individuals and to discover how this improvement is related to heavy drinking behavior. DESIGN: Double-blind, randomized, controlled, 12-week clinical trial comparing topiramate vs placebo for treating alcohol dependence (1998-2001). PARTICIPANTS: One hundred fifty alcohol-dependent individuals, diagnosed using the DSM-IV. INTERVENTIONS: Seventy-five participants received topiramate (escalating dose of 25 mg/d to 300 mg/d), and 75 had placebo and weekly standardized medication compliance management. MAIN OUTCOME MEASURES: Three elements of psychosocial functioning were measured: clinical ratings of overall well-being and alcohol-dependence severity, quality of life, and harmful drinking consequences. Overall well-being and dependence severity and quality of life were analyzed as binary responses with a generalized estimating equation approach; harmful drinking consequences were analyzed as a continuous response using a mixed-effects, repeated-measures model. RESULTS: Averaged over the course of double-blind treatment, topiramate, compared with placebo, improved the odds of overall well-being (odds ratio [OR] = 2.17; 95% confidence interval [CI], 1.16-2.60; P =.01); reported abstinence and not seeking alcohol (OR = 2.63; 95% CI, 1.52-4.53; P =.001); overall life satisfaction (OR = 2.28; 95% CI, 1.21-4.29; P =.01); and reduced harmful drinking consequences (OR = -0.07; 95% CI, -0.12 to -0.02, P =.01). There was a significant shift from higher to lower drinking quartiles on percentage of heavy drinking days, which was associated with improvements on all measures of psychosocial functioning. CONCLUSIONS: As an adjunct to medication compliance enhancement treatment, topiramate (up to 300 mg/d) was superior to placebo at not only improving drinking outcomes but increasing overall well-being and quality of life and lessening dependence severity and its harmful consequences.

Administration, Oral↗

PubMed1979

Relationship of sociodemographic and drinking variables to differentiated subgroups of alcoholics.

The results suggest that the sociodemographic variables of age, living arrangements, number of dependents, the drinking variable, and the client's perception of the type of drinker he is are the most strongly related to the derived typology. The exact relationship of these variables, as well as the variables that were moderately related to the typology, is not apparent. There is a pattern, however, that appears to run through the categories of the classification. The evidence suggests that for alcoholics to be in their prime earning years, living with their spouses, perceiving themselves as alcoholic, possessing marketable skills, and a recent history of abstinence seems to increase the likelihood of psychological need satisfaction. The antithesis--to be alcoholic, less than 30 or older than 50 years old, living by oneself or with parents, perceiving oneself as a social or problem drinker, and possessing a recent history of drinking--seems to decrease the likelihood of psychological need satisfaction. There seems to be a relationship between drinking behavior and psychological need satisfaction. As a group, the members of Clusters Two, Three, and Four are unable to abstain for longer than a week; Clusters Two and Three both possess physiological problems of adjustment. The members of Clusters One and Five tend to be able to abstain for longer periods. Cluster One is devoid of physiological difficulties, whereas Five has borderline problems. The physiological subscale of the Human Service Scale assesses the absence of symptoms associated with poor health (Realges & Butler, 1976). It appears that aberrant drinking does not necessarily result in self-perceived physiological-health complaints. These results are at variance with the belief that ethanol ingestion by an alcoholic and the resulting pathological complications are the predominant difficulties encountered by these persons. Thus it seems to us that a distraught life situation (that is, the lack of social and demographic assets--marriage, education, and so on) contributes to self-perceived severity of psychological need deprivation and not solely aberrant drinking. Therefore, in terms of recovery from alcoholism, these results argue against a unidimensional approach toward the treatment of alcoholism; that is, an approach that focuses solely on the drinking as "the" problem. A more strategic approach would include a thorough medical, psychiatric, psychological, social and vocational evaluation of the alcoholic's life situation, which in turn would permit mobilizing the efforts of a multidisciplinary team whose goal would be to maximize the resources and enhance the life situation of the alcoholic. It is hoped that the results of this study serve to increase our understanding of those factors that influence aberrant drinking.

Adult↗

PubMed1993

Photographically portrayed identities, alcohol expectancies, and excessive drinking.

A new measure of alcohol-related identity was derived from college students' photographic self-depictions using Ziller's (1990) autophotographic essay task. This measure and the well-developed Alcohol Expectancy Questionnaire (AEQ; Brown, Goldman, Inn, & Anderson, 1980) were used to predict frequency and typical quantity of drinking. Replicating past research, the AEQ showed a number of significant relationships with drinking behavior. The alcohol identity measure also correlated with these measures, even when variance attributable to the AEQ was controlled, and related particularly well to the typical quantity measure. It is suggested that the autophotographic essay method has heuristic value for alcohol research and other personality phenomena.

Adolescent↗

PubMed2004

Alcohol drinking patterns by gender, ethnicity, and social class in Bahia, Brazil.

OBJECTIVE: To study patterns of alcohol consumption and prevalence of high-risk drinking. METHODS: A household survey was carried out in a sample of 2,302 adults in Salvador, Brazil. Cases of High-Risk Drinking (HRD) were defined as those subjects who referred daily or weekly binge drinking plus episodes of drunkenness and those who reported any use of alcoholic beverages but with frequent drunkenness (at least once a week). RESULTS: Fifty-six per cent of the sample acknowledged drinking alcoholic beverages. Overall consumption was significantly related with gender (male), marital status (single), migration (non-migrant), better educated (college level), and social class (upper). No significant differences were found regarding ethnicity, except for cachaça (Brazilian sugarcane liquor) and other distilled beverages. Overall 12-month prevalence of high-risk drinking was 7%, six times more prevalent among males than females (almost 13% compared to 2.4%). A positive association of HRD prevalence with education and social class was found. No overall relationship was found between ethnicity and HRD. Male gender and higher socioeconomic status were associated with increased odds of HRD. Two-way stratified analyses yielded consistent gender effects throughout all strata of independent variables. CONCLUSIONS: The findings suggest that social and cultural elements determine local patterns of alcohol-drinking behavior. Additional research on long-term and differential effects of gender, ethnicity, and social class on alcohol use and misuse is needed in order to explain their role as sources of social health inequities.

Adult↗