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[The importance of house dust mites and stored food mites as house dust allergens in the rural population].

House dust samples from rural districts contain more mite species (in particular stored food mites) than samples from urban areas, and the total number of mites is also approximately three times greater. 77 patients from rural districts, 48 of whom allergic to their own house dust, and 29 controls, were tested with mite extracts from Dermatophagoides pteronyssimus, D. farinae, Chortoglyphus arcuatus, Acarus siro, Glycyphagus destructor and Tyrophagus putrescentiae, and a house dust extract. Out of 32 patients who showed positive scratch tests to one or more mite extracts, 29 (90,6 percent) reacted positively to D. pteronyssimus, 25 (78.1 percent) to D. farinae and from 7 to 12 (20-40 percent) to the stored food mites. Out of the 48 patients allergic to their own house dust, 27 (56.2 percent showed positive reactions to D. pteronyssinus, 24 (50.0 percent) to the house dust extract and 21 (43.7 percent) to D. farinae. Only 5 (17.2 percent) out of the 29 controls reacted positively to one or more of the solutions tested. The stored food mites showed 2.5 to 4.5 times more positive reactions in the rural patients compared with the results obtained in urban patients. The importance of these mites in the sensitization of patients from rural districts is discussed.

Adolescent↗

[Mite dermatitis due to Tyrophagus dimidiatus].

This paper describes a small endemic with acarus Tyrophagus dimidiatus in a butcher's family originating from contaminated meat. The morphology and biology of this parasite are discussed.

Acari↗

Sensitization in a grain handler to the storage mite Lepidoglyphus destructor (Schrank).

Allergy to one of the most common Canadian storage mites. Lepidoglyphus destructor, was demonstrated in a grain worker by immediate skin testing and inhalation challenge. The frequency of sensitization to this mite was found to be 12% in 100 asthmatics by skin testing. In 4% of these asthmatics sensitization to another storage mite, Acarus siro, was found, all of whom were also sensitized to L. destructor and the house dust mite, Dermatophagoides farinae. There was a significantly higher proportion of asthmatics sensitive to the storage mites and to fungi who had a history of exposure to grain compared to those who did not.

Asthma↗

[IgE values in nasal mucus in the diagnosis of perennial allergic rhinitis].

Perennial rhinitis may be caused by an allergic response or by the vasomotor reaction to cholinergic hyperactivity. The differential diagnosis of these etiologic forms poses a difficult problem for the clinicians. The pathophysiology of rhinitis is characterized by vascular ingurgitation and mucous edema, phenomena which may result from such diverse etiologic factors as cholinergic hyperactivity and allergy. In our study, we will evaluate total IgE levels in nasal secretions, irrespective of serum of local origin. Fifty-four patients suffering from perennial rhinitis, aged between 7 and 63 years, were studied. Fourteen presented vasomotor rhinitis, while the remaining 40 were affected with the IgE-dependent form. The following tests were done: blood eosinophil count, mucous eosinophyl count, serum IgE (PRIST), cutaneous tests with house dust, acarus and fungal antigens and nasal provocation tests. IgE levels in mucous were also evaluated. The following results were obtained: 1. No significant differences were found in blood eosinophil counts between the groups studied. 2. No significant differences were found in serum IgE levels between the groups studied. 3. Significant differences were found (P less than 0.001) in the levels of eosinophils in mucous among the groups studied. 4. Mucous IgE levels are significantly greater in the allergic form than in the vasomotor form of rhinitis. The level of IgE in mucous serves as a useful but not pathognomic parameters in the differential diagnosis of the different etiologic forms of rhinitis. As such it should be considered within the context of all clinical and analytic data before a conclusive diagnosis is made.

Adolescent↗

[Prevalence of immediate allergy to respiratory allergens in fodder farmers in Doubs].

The Doubs is a damp, semi-mountainous fodder farming department in which occupational respiratory diseases (including asthma) are common in farmers. We studied the prevalence of IgE-mediated allergy (total IgE, Phadiatop and skin prick tests) in a group of 265 exclusive dairy farmers of both sexes of the department and in a control group of non exposed, administrative workers living in the same area. Skin prick tests were: Dermatophagoides pteronyssinus, Acarus siro, cat hair, cow danders, grass pollens, betullacea pollens (trees from the East of France), and hay extracts from the Doubs. Total IgE were higher than 180 KUI/l in 26 (9.9%) farmers and in 15 (10.5%) controls (NS). Phadiatop was positive in 41 (15.7%) farmers and in 27 (19%) controls (NS). Prevalence of positive skin prick tests (at least one) in farmers and controls was respectively 36% and 40% (NS). Farmers were more frequently sensitized to hay extracts (OR = 1.7), cow danders (OR = 1.3) and less frequently to cat hair (OR = 0.63) than controls but the differences were not statistically significant. In conclusion, this study fails to give evidence of a risk of IgE-mediated allergy to work-related and other common inhalation allergens in dairy farmers the Doubs.

Adult↗

[Skin tests for different species of acari in asthmatic children from Mexico City].

House dust mites, Dermatophagoides pteronyssinus (Dp) and Dermatophagoides farinae (Df) are the predominant cause of allergic asthma in our population. To detect the presence of sensitivity to other mites besides Dp and Df in 100 children that live in Mexico City, skin tests were performed in their arms with Multi-test devices and glycerinated extracts. There were 34 female and 66 male, aged 4 to 14 years (x = 9.1y), with history of mild and moderate asthma, 2 months to 12 years of evolution. Dp was positive in 96, Df in 80, Euroglyphus maynei in 41, Chortoglyphus in 22, Blomia tropicalis in 17, Trophagus putrescentiae in 12, Glycphagus in 12, Acarus siro in 7, Lepidoglyphus destructor in 7 and Gophieria in 7. Hypersensitivity to all of th species was common. Even we know about the cross-reactivity between them, there are species-specific allergens that could make some of them important in diagnosis and treatment.

Adolescent↗

Occupational allergy to mites in salty ham, chorizo and cheese.

We present three cases of occupational allergy caused by the manipulation of food: cheese, chorizo (typical Spanish salami) and salty ham. A IgE-mediated sensitization is demonstrated by skin tests, RAST and positive challenge tests to Acarus siro and Blomia kulagini of the cheese rind, Euroglyphus maynei of the "chorizo" and Tyrophagus putrescentiae of the salty ham.

Adult↗

Study of the sensitization to storage mites in a pediatric population in Barcelona.

We performed the following study in order to determine the prevalence and characteristics of sensitization to storage mites in children mostly from the city of Barcelona. All children over 3 years of age attending our unit for the first time due to respiratory problems were given cutaneous tests using the prick test for the house dust mites Dermatophagoides pteronyssinus and D. farinae, and the storage mites Acarus siro, Lepidoglyphus destructor and Tyrophagus putrescentiae. We carried out a RAST and conjunctival test when it was considered appropriate. Of a total of 356 children studied, 39 showed cutaneous sensitization to storage mites, which represented 11% of the population studied, and 20% of the total sensitized to mites. However, only 3 of these children were only sensitized to storage mites, the remaining 36 (92%) also showing sensitization to house dust mites. Of the storage mites studied, L. destructor was the most significant. A history of immunotherapy to mites was associated with a greater percentage of positive cutaneous tests to storage mites, although this was not the case with the RAST test.

Animals↗

Hypersensitivity to chironomid larvae.

Chironomid larvae (red midge larvae) are often used by aquarists as fish food. Their hemoglobins can cause IgE-mediated allergic diseases in exposed and unexposed people. The aim of this study was to find out the prevalence of positive skin tests to chironomids in patients suffering from rhinitis and/or bronchial asthma in Ciudad Real (Spain). A total of 465 patients were submitted to skin prick tests with chironomids in addition to common inhalant allergens. The patients with positive skin prick test (wheal > or = 3 mm) to these larvae answered a questionnaire. Skin prick tests with Acarus siro, shrimp, cockroach and mosquito (Culex pipiens) were carried out. Serum levels of total IgE and anti-Chironommus thummi, anti-Dermatophagoides pteronyssinus, anti-shrimp, and anti-mosquito (Aedes communis) IgE were determined. Conjunctival or nasal provocation tests were carried out with chironomids. Of the 465 patients skin tested, 19 showed a positive skin prick test with chironomids, corresponding to 4.1% of all patients and 6% of the atopic patients. None were monosensitized. Significant correlations were found between skin prick test results with chironomids and mites (p < 0.005). Of the 19 patients, 15 had positive skin prick test with the common mosquito C. pipiens. Seven patients showed elevated anti-D. pteronyssinus IgE, six elevated anti-shrimp IgE, and 10 showed elevated anti-A. communis IgE. Provocation tests with chironomids were positive in 14 patients (four nasal and 10 conjunctival tests). Conjunctival provocation tests were carried out in 16 controls and were positive in three; all three showed positive skin prick test with chironomids. One patient had occupational allergy from the larvae (aquarist). After mosquito bites, five patients showed immediate wheal reactions and one patient suffered an anaphylactic reaction after several mosquito bites. Only two patients remembered having been in contact with chironomids as fish food. We found hypersensitivity to these larvae in patients without apparent contact to them. These patients could have become sensitized in various ways, including: 1) inhaling particles of chironomids or others that are cross-reactive with them; 2) exposure to products used as fish food containing chironomids; and, 3) through cross-reactivity with other allergens such as mites, shrimp or mosquitoes.

Adolescent↗