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[Bile-diverting anastomoses in tumorous obturation of the bile ducts].

The authors make an analysis of the operative treatment of 525 patients with cancer of the hepato-biliary and pancreatoduodenal zones. The distal, central and proximal obturations of bile ducts were found which determined the indications to formation of various bilio-digestive anastomoses. The operation of choice for distal obturation is a wide areflux cholecystogastrostomy with the use of blanket suture with the chromium-coated catgut. In the central and proximal obturation the precision suture with an atraumatic suture material and magnifying optics are recommended.

Ampulla of Vater↗

[Palliative surgery treatment].

Palliative surgery is still a major form of treatment in malignant biliary obstruction. Its results, however, have to be compared with those of non-surgical methods. The quality of life is often excellent after palliation, even when the slightly higher mortality and morbidity rates are taken into account. Furthermore, the case of curative resection is often decided peroperatively, and this chance should be given to every patient for whom there is no definite contraindication to resection during the preoperative assessment.

Anastomosis, Roux-en-Y↗

[Experiences with determining carcinoembryonic antigen in tumors of the digestive tract].

CEA levels (CEA = carcino-embryonic antigen) were checked as indicators for the presence of malignant diseases of the gastro-intestinal tract. Tests were applied to 1,102 blood samples, including 1,012 relating to malignant alterations of the digestive tract and 32 relating to benign changes. Sixty-eight samples were taken from tumours localised elsewhere. The importance is stressed of high-continuity observation of CEA levels which have proved to enable dimensional assessment of colorectal carcinoma. Presurgical and postsurgical CEA values can be related to surgical radicality. Regular postoperative monitoring is recommended for prognostication, early detection of recurrences, and early assessment of spreading of the disease.

Adenoma, Islet Cell↗

[Achievements of tumor surgery in tumors of the liver and bile ducts].

Tumor surgery in this field is no longer such a high risk as previously. Prolonged survival can be achieved by resection of hepatocellular carcinomas in non-cirrhotic livers (3-year survival 58%, n = 54 patients) and for colorectal liver metastases (3-year survival 44%, n = 124 patients). But surgery is rarely successful for the most frequent type of liver malignancy, the hepatocellular carcinoma in cirrhosis. Central bile duct carcinomas are now resected more frequently than in the past. Liver grafting seems indicated in special cases of liver and bile duct tumors. The future developments of operating on the in situ-perfused liver was discussed and the first operation on an ex situ-liver was demonstrated.

Bile Duct Neoplasms↗

Diagnosis of obstructive jaundice.

The diagnosis of obstructive jaundice remains difficult yet vital, since operative decompression may relieve extrahepatic blockage, but operation can only harm patients with intrahepatic block or parenchymal cell inflammation or necrosis. Three new diagnostic methods (liver scanning, angiography, and transjugular transhepatic cholangiography) are reviewed, as is bilirubin metabolism, so important in the diagnosis of jaundice. Three clinical problems are discussed: extrahepatic obstruction due to cancer of the pancreas, biliary atresia causing jaundice in the newborn, and the diffuse ductal obstruction known as sclerosing cholangitis.An accurate diagnosis can usually be made with standard diagnostic techniques, such as history, physical examination and biochemical tests, and, when appropriate, gastrointestinal x-ray studies, cholecystography and cholangiography, liver biopsy, observation of the patient's course, and the three new radiological approaches mentioned above. Extrahepatic obstructive jaundice is an indication for surgical treatment, except perhaps in cases of sclerosing cholangitis.

Adult↗