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Results for “HYPOTHALAMUS/physiology”

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At least 145 records · Page 8Linked to original sources
PubMed1957

Hypothalamo-neurohypophysial involvement in the corticotrophic action of acetylcholine.

Acetylcholine produced a fall of blood eosinophils and adrenal ascorbic acid in normal rats; these effects did not occur in hypophysectomized animals or in hypophysectomized animals bearing a pituitary homotransplant in the anterior chamber of the eye. Acetylcholine had a striking and long-lasting antidiuretic effect in normal rats, which was abolished by hypophysectomy. In normal dogs, intravenous injections of acetylcholine raised the concentration of posterior pituitary antidiuretic hormone in the cerebrospinal fluid. These results are discussed in connexion with the hypothesis that posterior pituitary antidiuretic hormone may be the neurohumoral substance involved in the hypothalamic control of the anterior pituitary.

Acetylcholine↗
PubMed1957

Effects of reserpine on blood-pressure responses evoked from the hypothalamus.

Different areas of the hypothalamus were stimulated by a stereotaxic technique before and after reserpine in unanaesthetized cats. Reserpine in a dose of 1 mg./kg. body weight increased the threshold of stimulation of hypothalamic areas in cats giving an initial pressor response. It decreased the threshold of stimulation of areas of the hypothalamus in animals giving an initial depressor response. Reserpine thus appeared to affect the hypothalamus directly in two ways. It depressed the sympathetic centres in the diencephalon and facilitated the parasympathetic ones.

Animals↗