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Results for “Histocompatibility Testing”

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At least 145 records · Page 8Linked to original sources
PubMed1964

LYMPHOCYTE INTERACTION: A POTENTIAL HISTOCOMPATIBILITY TEST IN VITRO.

Lymphocytes from two unrelated individuals, cultured together in the same tube, undergo morphological transformation to large cells and divide. Both of these parameters may be estimated quantitatively. There is a correlation between the degree of this response and the degree of cross-reactivity of grafts from the two individuals placed on a third unrelated recipient.

Allergy and Immunology↗
PubMedDate not supplied

Haploidentical transplantation. Importance of histocompatibility testing and chimerism studies in allogeneic bone marrow/stem cell transplantation.

The transplantation of hematopoietic stem cells is sometimes the only treatment option for certain types of malignancies and hematological disorders. The best way to ensure a positive outcome from this type of procedure is to secure an identical human lymphocyte antigen-matched donor or use an autologous graft. This article reviews the indications for transplantation, the recipient and donor selection process, and posttransplant follow-up. The advantages of using haploidentical donors and the typing process also will be discussed.

Chimera↗
PubMed1981

Comparative histocompatibility testing of seven calcium phosphate ceramics.

Five hydroxyapatite and two tricalcium phosphate ceramics were implanted in rat femora for one to six months. They were compared with each other in regard to biocompatibility and bone induction. After one month bone had grown directly on to the surface of all implants. After six months the on-growth of bone had increased with the exception of two dense HA materials. In these materials some bio-degradation had occurred with subsequent formation of a wide macrophage interlayer. Bio-degradation and biocompatibility of calcium phosphate ceramics seem to depend not only on density but also on other factors. Induction of bone could not be observed in soft tissue environment.

Animals↗