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At least 145 records · Page 8Linked to original sources

PubMed1982

Acquired subglottic stenosis following prolonged endotracheal intubation. A canine model.

We developed a canine animal model of subglottic stenosis following prolonged intubation with modified non-cuffed endotracheal tubes. None of the puppies intubated for seven days had an irreversible stenosing subglottic lesion, whereas all animals intubated for 14 days or more had at least a 40% to 50% reduction of the subglottic lumen secondary to maturing fibrotic stenosis. The model described is more congruent with the known and suspected pathogenesis in those infants and children who require prolonged endotracheal intubation and subsequently acquire subglottic stenosis, and can be used in evaluating the efficacy of medical therapy or surgical therapy, or both, in the prevention or management of this disease.

Animals↗

PubMed1983

Conjoint hyoid bone segments for the repair of severe laryngeal stenosis.

We discuss and show by illustrations a surgical technique for the management of severe combined laryngeal and subglottic stenosis using multiple pieces of hyoid bone. No serious problems resulted from the removal of the entire hyoid bone. All patients have maintained a good airway, despite the possibility of absorption of a free bone graft. Although it is reasonable to try to use the hyoid bone with a strap muscle pedicle, it is impossible to reconstruct the subglottic and laryngeal area without multiple pieces. Our experience encourages us to use multiple pieces of free hyoid bone for laryngotracheal reconstruction.

Adult↗

PubMed1987

Proximal large-bore jet ventilation for laryngeal laser surgery.

The carbon dioxide surgical laser has made many open upper airway operations obsolete. However, new laser-related hazards have been encountered, the most serious of which is fire in the airway. Venturi jet ventilation removes that risk and provides an unobstructed surgical field. Indications and techniques for the use of jet ventilation with carbon dioxide laser surgery remain controversial, particularly whether jet ventilation should be used in papillomatosis or in the severely obstructed airway, and whether proximal and distal catheter techniques are equally safe and effective. We report the successful use of proximal large-bore Venturi jet ventilation in 327 consecutive patients undergoing microlaryngeal laser surgery. The technique is ideal for pediatric patients with subglottic stenosis or recurrent respiratory papillomas and has not caused distal seeding in the latter group. We recommend the use of low-pressure ventilation, even in relatively obstructed airways. The experimental evidence reported here corroborates the clinical viewpoint expressed; the technique is safe, simple, and uncomplicated if used with care.

Adult↗

PubMed1987

Prolonged intubation of neonates.

As the capabilities of modern medicine allow the survival of babies with increasingly lower gestational ages and birth weights, there is an increasing concern regarding the development of subglottic stenosis in those infants subjected to prolonged intubation. In this study, the general safety of neonatal intubation is assessed by a retrospective analysis of neonates who required intubation at Columbus (Ohio) Children's Hospital during a three-year period from 1977 to 1980. Of 343 surviving neonates, five (1.5%) developed clinically significant subglottic stenosis. The conclusion of this study is that endotracheal intubation is a safe method of airway management in neonates, even when used for extended periods.

Humans↗

PubMed1987

Laryngotracheal reconstruction. Sternohyoid myocutaneous rotary door flap.

The vascularized sternohyoid myocutaneous rotary door flap has been used for laryngotracheal reconstruction in ten patients in the past two years. Nine were reconstructed for laryngotracheal stenosis and one for immediate reconstruction after conservation laryngeal surgery for carcinoma. Before reconstruction, the nine patients with stenosis had each undergone a mean of eight surgical attempts at correction. Eight patients were tracheostomy dependent, and only two patients had effective voices. To date, seven patients have been decannulated and all ten have effective voices. No significant complications have been noted. This flap can provide a readily applicable, dependable technique that is useful in management of difficult laryngotracheal stenosis and for reconstruction after conservation laryngeal surgery.

Adult↗

PubMed1988

Reconstruction of the larynx and trachea.

This article involves an analysis of 43 patients who underwent 64 reconstructive procedures for laryngeal and/or tracheal defects at The Ohio State University (Columbus). The purpose of this report is to analyze the results of a variety of reconstructive techniques in order to formulate a recommended therapeutic approach. Utilizing this therapeutic approach, 77% of the reconstructions were totally successful in providing an airway not requiring a tracheotomy tube and a voice capable of communication. Another 16% of the reconstructions were considered partially successful, requiring a permanent airway tube due to limitations created by coexisting health problems. There have been no patients where airway reconstruction was totally unsuccessful. A generalized approach to reconstruction is presented.

Adolescent↗

PubMed1988

Anterior cricoid split, 1977-1987. Evolution of a technique.

Acquired subglottic stenosis is a well-documented complication of endotracheal intubation in infants. In past years, many of these patients required a tracheotomy for a period of years prior to laryngotracheal reconstruction. The anterior cricoid split procedure was developed as a method of treatment for severe laryngeal stenosis in infants and young children without resorting to a tracheotomy. An analysis of our institution's ten-year experience with 67 patients is presented, detailing the changes in surgical technique that have taken place over that time period. This is contrasted with alternative means of cricoid decompression advocated by other surgeons. Our review supports the efficacy of this procedure when there is strict adherence to certain criteria prior to the performance of the operation. Specifically, this operation should be restricted to neonates or young infants whose pathology is limited to the glottis and subglottis or both, and in whom there is adequate pulmonary reserve.

Child, Preschool↗

PubMed1988

The anterior cricoid split. Clinical experience with extended indications.

A recommended approach to postextubation infant subglottic stenosis secondary to subglottic edema employs the recently described anterior cricoid split (ACS) procedure. This technique provides an expanded subglottic airway with minimal paratracheal dissection and does not require concomitant tracheotomy. We applied this procedure in managing extubation difficulty in pediatric as well as neonatal patients. Five of ten patients in our series did not fulfill the traditional criteria for ACS. Relief of stridor and avoidance of tracheotomy were accomplished in nine of ten patients. One patient in whom mechanical ventilation was reinstituted developed an interesting complication. In properly selected infants with subglottic airway compromise, the ACS appears to be an effective adjunct in facilitating extubation.

Child, Preschool↗

PubMed1989

Inherited nasal and laryngeal degenerative chondropathy.

Four rare cases of congenital saddle-nose deformity and slowly progressive degeneration of laryngeal cartilages with stenosis are described. The term inherited degenerative chondropathy is suggested for this disease entity. To our knowledge this is the first article on such a disease.

Adolescent↗

PubMed1990

Subglottic cysts in the premature infant.

Supraglottic cysts in the newborn are a well-recognized entity, but subglottic cysts have been rarely reported. Over the past 6 years we have observed subglottic cysts in nine patients with relatively long intubations from the neonatal intensive care unit of two university hospitals. Most frequently the patients were extubated and did well for weeks or months, but then they had progressive biphasic stridor. On endoscopy the patients had a subglottic stenosis that was irregular but with a smooth mucosal lining. Usually the cysts were apparent, but in two patients the mucosa was thickened and the patients were treated as a subglottic stenosis with tracheostomy. These subglottic cysts were recognized at the time of laryngotracheoplasty. In six patients the cysts were managed either by marsupialization with cup forceps, endoscopic diathermy, or carbon dioxide laser without recurrence. It is our belief that this condition is most likely due to scarring and obstruction of mucus glands of the subglottic area from prolonged intubation. This entity should be recognized and looked for in the neonate who has an acquired subglottic stenosis and should first be treated conservatively with endoscopic marsupialization.

Child, Preschool↗

PubMed1990

Surgical treatment for laryngotracheal stenosis in the pediatric patient.

We report our experience with laryngotracheal stenosis (LTS) in children during the last 12 years. Documentation and follow-up were available for 115 patients who underwent surgery for acquired or congenital LTS. Most were severe cases according to Cotton's classification. Forty-six weighed less than 10 kg at the time of surgery; 45 had pure congenital subglottic stenosis; 70 had acquired subglottic stenosis, mainly due to endotracheal intubation. The surgical techniques used have been various. The three main types of procedure were castellated laryngotracheoplasty, anterior cartilage rib grafting, and anterior and posterior cricoid cuts with or without grafting. All cases but 1 (44/45) of congenital subglottic stenosis have been successfully decannulated, 7 requiring a second procedure. The decannulation rate for acquired SGS was 89% (62/70), but 14 patients required multiple procedures. Current trends in subglottic stenosis management in our institution are presented.

Adolescent↗

PubMed1991

External fixation using microplates after laryngotracheal expansion surgery. An animal study.

Management of severe laryngotracheal stenosis requires treatment with open laryngeal surgical approaches. Performing the necessary anterior, and possibly posterior, incisions to expand the cricoid and tracheal rings causes instability of the segments. Placing an intraluminal stent has several disadvantages, ranging from injury of healthy tissue to airway obstruction. The availability of an external stent would avoid many of these complications. We performed expansion laryngeal surgery in dogs and explored the use of microplates for external fixation and determined the surgical outcome if no fixation is used. The results show that microplates are very effective in maintaining external fixation and that a need for placing an intraluminal stent when a posterior cricoid split is performed exists.

Animals↗

PubMed1991

Single-stage laryngotracheal reconstruction.

The mainstay for repairing subglottic and tracheal stenosis has been the rib graft with prolonged stenting. A refinement of this treatment was the use of the anterior cricoid decompression (split). We present single-stage reconstruction of the airway as an additional refinement of the laryngotracheoplasty. This article describes the experience of two institutions with single-stage reconstruction and offers some observations on the principles of the technique.

Adult↗

PubMed1991

Reconstruction of pediatric larynx and upper trachea with the sternohyoid rotary door flap.

The sternohyoid myocutaneous flap, the rotary door flap, is optimally oriented to serve in laryngotracheal reconstruction. It provides immediate, highly vascularized lining and structural support to the augmented airway. Therefore, it is one of the most versatile alternative methods available for surgical reconstruction of the stenosed larynx and trachea. Thirteen of 14 patients who were managed by the rotary door flap technique have been successfully decannulated. The features of the flap and the surgical technique are described with reference to modifications in the pediatric age group.

Adolescent↗

PubMed1991

One-stage laryngotracheoplasty.

This article documents the evolution of our approach to the repair of subglottic stenosis in infants. With increasing experience in the management of subglottic stenosis using the anterior cricoid split procedure, we extended our procedure to include older children. This then led to the use of the one-stage procedure for repair of severe and mature subglottic stenosis. We present the results of surgical repair in 13 patients. Extubation was accomplished in 12 of 13 patients using one-stage laryngotracheoplasty.

Child↗

PubMed1991

Laryngeal airway resistance. The relationships of airflow, pressure, and aperture.

In the surgical treatment of the paralyzed larynx, a compromise often needs to be made between an orifice size needed to preserve voice and that needed for adequate inspiratory airflow rates. To assess the negative pressures needed to generate normal airflows across a narrowed vocal cord aperture, we measured pressure and flow changes across cadaveric larynges while altering aperture size. Best-fit quadratic equations for each aperture area selected were derived and showed that if the aperture were 0.5 cm2 or less, the resistance to normal breathing would be significantly increased. Aperture sizes of 0.67 cm2 or greater are not associated with such an increase in resistance.

Airway Resistance↗

PubMed1992

Anastomosis of the cervical trachea in children.

Numerous techniques for the surgical management of laryngotracheal stenosis in children have been described in the literature. These surgical modalities include endoscopic management and open laryngotracheal reconstruction using costal cartilage grafts for expansion of the stenotic subglottic region. Although tracheal resection with primary reanastomosis for the management of tracheal stenosis is reported frequently in the adult population, children rarely have stenotic lesions that are amenable to this particular technique. Laryngotracheal stenosis in children most commonly involves the subglottis. This makes tracheal resection with anastomosis technically difficult to perform, due to the close proximity of the vocal cords. We have found a subpopulation of children at our institution with high tracheal stenoses, with minimal lower subglottic involvement, who were amenable to tracheal resection with primary anastomosis. We review our experience with this technique. The indications for this surgical modality in children are discussed, as well as the surgical technique.

Adolescent↗

PubMed1992

Four-quadrant cricoid cartilage division in laryngotracheal reconstruction.

Four-quadrant division of the cricoid cartilage is a relatively new technique of laryngotracheal reconstruction. Division of the lateral walls of the cricoid cartilage, with or without placement of autogenous cartilage grafts, allows for increased expansion of the subglottic lumen. Between October 1, 1986, and January 1, 1990, 185 laryngotracheal reconstructions were performed at our institution. During that time, 31 four-quadrant division laryngotracheal reconstruction procedures were performed in 29 patients (mean age at surgery, 5 years 5 months). Grade 3 or 4 laryngeal stenosis existed preoperatively in 72% (22/31) of cases. The initial decannulation rate after four-quadrant division laryngotracheal reconstruction was 58% (18/31). Of 11 patients requiring revision surgery after four-quadrant division laryngotracheal reconstruction, four were eventually decannulated, for an overall decannulation rate of 76% (22/29). The indications, technique, results, and potential complications of four-quadrant division of the cricoid cartilage in laryngotracheal reconstruction are discussed.

Adolescent↗