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Laryngeal phonatory reflex. The effect of anesthetization of the internal branch of the superior laryngeal nerve: Acoustic aspects.

Summary--The laryngeal phonatory reflex through the internal branch of the superior laryngeal nerve (SLN) was investigated by means of anesthetization of the nerve, after which acoustic signals were subjected to computer analysis to determine how anesthesia affected basic vocal parameters. Results showed that the anesthetization did not affect the abrupt cycle-to-cycle frequency changes and also did not influence the gross control of the fundamental frequency. But slower fluctuation of the fundamental frequency increased following anesthesia. From these results, it is suggested that the anesthetization of the internal branch of the SLN may derange the fine control mechanism of the larynx without affecting overall or gross performance of the phonatory apparatus.

Humans↗

[Brain stem audiometry and metrizamide-meatocisternography in diagnosis of small neurinomas of the acoustic nerve (author's transl)].

Reviewing the newest literature, an acoustic neuroma can be detected in 96% of the cases, employing brainstem audiometry. The present study aims to answer the question how good small acoustic neuromas can be detected using this method. Fifty patients with an asymmetric hearing loss, with unilateral caloric deficit and short lasting periods of dizziness when changing position were investigated. Brainstem audiometry as well as metrizamide-meatocisternography were carried out. Thus we were able to detect seven small acoustic neuromas; only one tumor could not be detected with the brainstem audiometry. The findings will be shown and discussed.

Adult↗

Presurgical electrophysiological findings in acoustic nerve tumours.

The clinical involvement of the facial nerve is a rare finding among the initial symptoms of acoustic neurinomas. However, compression of the facial nerve is a common intraoperative finding. Blink reflex was recorded in 20 patients affected by cerebellar-pontine angle tumor confirmed at surgery. Recordings were also made of the M-response of the facial nerve from the naso-labial folds. In 6 cases jaw reflex was also recorded. In summary, these electrophysiological studies revealed a facial nerve damage in 13 and a trigeminal nerve dysfunction in 2 out of 18 clinically unaffected patients. The combined study of the 3 tests proved to be useful when the blink reflex showed an isolated R1 delay, that is, in cases in which the level of damage along the trigemino-facial reflex arc cannot be defined by the recording of the blink reflex alone.

Adolescent↗

[Tumor-induced function disorders of the acoustic nerve and the lower portions of the auditory pathway].

The manyfold features of acoustic neuromas, respectively tumors of the cerebello pontine angle, are tried to explain by pathophysiologic phenomena of the neural conduction. They are the pathologic fatigue of hearing, the disturbed excitability of the acustico facial stapedial reflex, the impaired velocity of nerve conduction, a poor synchronization of conduction as well as the excessively reduced monosyllabic and dichotic discrimination. With respect to the original tissue, localization, size as well as regional spread and growth pressure there result different constellations of symptoms, eventually only marked discretely. However, all 35 tumors of a defined observation period as well could be diagnosed solely by functional hearing tests.

Adult↗

Acute acoustic nerve palsy associated with vincristine therapy.

A 73-year-old woman with non-Hodgkin's lymphoma had two episodes of severe, bilateral, sensori-neural hearing loss after vincristine therapy. Her hearing gradually, then completely returned 2-3 months after the vincristine therapy was discontinued. Bilateral ear infections, central nervous system lymphoma and infection, or other drug-induced neuropathies were excluded as possible etiologies for the deafness. Bilateral acoustic (VIII) nerve palsy in this patient was most likely a manifestation of vincristine neurotoxicity.

Aged↗