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At least 145 records · Page 8Linked to original sources
PubMed2004

Primary hyperparathyroidism presenting as a palatal brown tumor.

Only 2% of all primary hyperparathyroidism cases occur in patients below the age of 30 years. Owing to the improved methods of blood analysis in the last 2 decades, most of the recent cases of primary hyperparathyroidism are diagnosed early and asymptomatically. This makes advanced disease with bone lesions extremely rare these days. A case of a 25-year old female patient with previously undiagnosed primary hyperparathyroidism who presented first with palatal swelling is reported. Further investigations revealed parathyroid adenoma, nephrocalcinosis, and extensive bone lesions involving the maxillary sinus and palate as well as the pelvic bone. The evaluation of the hyperparathyroid patient is reviewed in this report. The methods of treatment of the bony lesions of primary hyperparathyroidism are also discussed.

Adenoma↗
PubMed1999

Immunohistochemical localization of the bone morphogenetic protein-6 in salivary pleomorphic adenomas.

Salivary pleomorphic adenomas are often associated with chondroid tissue formation. We have found that bone morphogenetic proteins (BMP), especially BMP-2, may play an important role in ectopic chondrogenesis in this tumor. Bone morphogenetic protein-6 was reported to be related to the osteogenic metastasis of prostatic carcinomas. The relationship between BMP-6 expression and chondroid tissue formation is investigated. Twenty-three pleomorphic adenomas were examined immunohistochemically. The overexpression of BMP-6 was observed in 10 pleomorphic adenomas of the major salivary glands (43. 5%), and no evidence of BMP-6 expression in any of the nine pleomorphic adenomas of the palate. Bone morphogenetic protein-6 was immunolocalized in the lacuna cells of the chondroid tissue, in which type II collagen was localized. Bone morphogenetic protein-6 was expressed in inner ductal cells of the tubulo-glandular structures in the pleomorphic adenomas. This finding indicates that BMP-6 may be associated with the differentiation of inner ductal cells. Bone morphogenetic protein-6 was expressed weakly in neoplastic myoepithelial cells in the myxoid areas, which may be related to the production of extracellular matrices. Bone morphogenetic protein-6 has a role in chondroid formation, and also tubulo-glandular differentiation in pleomorphic adenomas. In conclusion, a large portion of pleomorphic adenomas of the salivary gland origin, but not of palate origin, was shown to overexpress BMP-6 protein.

Adenoma, Pleomorphic↗
PubMed2006

Surgical repair of unidirectional palatopharyngeal epignathus: Case report and review of literature.

Epignathus is an extremely rare, benign, congenital teratoma that arises from within the oral cavity and may be attached to the mandible, palate, or base of the skull. Because of its location, it can cause airway and feeding problems, as well as secondary defects due to the presence of an intraoral tumor. This tumor usually causes death in neonates, due to airway obstruction. Surgical removal is usually impossible, especially in large tumors (Stone, 1951; Bennett, 1970). A patient with a neonatally diagnosed nonobstructive palatopharyngeal epignathus is described. It was associated with a shortened palate, cleft uvula, and velopharyngeal insufficiency, and was successfully excised surgically.

Child, Preschool↗
PubMed1991

[Current techniques of pharyngo-velar reconstruction after excision for cancer].

Carcinological surgery of the pharyngo-velar region poses delicate problems of reconstruction in exereses exceeding the midline. To avoid false alimentary pathways through the nose and phonatory problems (open rhinolalia), we propose the use, with or without the combination of a muscular cutaneous flap, of a free antecubital flap or of a latter is apparently fully satisfactory on the functional plane with the additional advantage of not leaving any aesthetic sequellae.

Humans↗
PubMedDate not supplied

Central cementoossifying fibroma of the maxillary sinus: a review of six cases.

We present the radiographic findings of six patients with central cementoossifying fibromas of the maxilla. CT typically demonstrated large, spherical tumors in the maxillary alveolar ridge, filling and expanding the maxillary sinus and extending to involve the ipsilateral hard palate. The central tumors ranged from having soft-tissue density with scattered foci of high density to being heavily calcified.

Adult↗
PubMed1994

The management of salivary gland tumors of the palate.

A study of 22 consecutive patients with palatal salivary gland tumors treated in a structured fashion with primary surgery followed by postoperative radiation therapy, where indicated, and followed for a mean of 7.6 years, showed excellent results clinically, esthetically, and functionally, with no recurrence or metastatic deposits to date. Depending on the type of tumor, the surgery consisted of local enucleation, wide local excision with localized flap closure, or inferior maxillectomy with reconstruction by means of an obturator.

Adenocarcinoma↗
PubMed2004

Sialadenoma papilliferum: immunohistochemical study.

Sialadenoma papilliferum (SP) is a rare benign tumour of salivary gland origin, which has been included among the ductal papillomas in the latest classification of tumours by the World Health Organisation. Two SP from the minor salivary gland of the palate of middle age patients were presented and studied by immunohistochemical. Our results showed presence of cytokeratins (CKs) 13, 14, 7, 8, 19 and absence of vimentin and smooth muscle actin. This immunoprofile is similar to the excretory duct of salivary gland.

Adenoma↗
PubMed2005

Calcifications in a clear cell mucoepidermoid carcinoma of the hard palate.

Although calcification is a common finding in inflammatory salivary gland disorders, salivary gland tumour rarely shows calcifications. A case of clear cell mucoepidermoid carcinoma (MEC) of the hard palate with extensive intratumoural calcifications visible on computed tomography (CT) scans and histologic sections is described. The calcification in the salivary gland tumour of the palate recognized by a CT scan should be considered in the differential diagnosis of a MEC. The mechanism of the intratumoural calcification in our case is speculated to be a result of a secretory function of the tumour cells.

Calcinosis↗
PubMed2004

Canalicular adenoma of the palate: case report and literature review.

Canalicular adenoma is a rare benign salivary gland tumor of the oral cavity, typically located in the upper lip and buccal mucosa and infrequently found on the palate. The tumor is usually confined to soft tissue and rarely presents with bone erosion. A case of a large and locally-aggressive palatal canalicular adenoma is presented. The lesion presented herein was an asymptomatic ulcerated mass with significant bone erosion. The tumor was managed surgically with excision and reconstruction of the resulting palatal defect with a full temporalis muscle flap.

Adenoma↗
PubMed1997

Regional metastasis in polymorphous low grade adenocarcinoma. Report of a case.

A case of cervical lymph node metastases of polymorphous low grade adenocarcinoma is reported, originating from a minor salivary gland in the soft palate in a 76-year-old man, 19 years after initial presentation. The clinical course, histopathology, and literature review on the metastatic aspect of the tumour are presented. This has emphasized the need for increased awareness of this recently described tumour and the need for lifelong follow up.

Adenocarcinoma↗