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[Puerperal infections. From Semmelweis to current problems].

Maternity hospitals began to be established in the middle of the 18th century to relieve the distress of the poor. As the number of lying-in hospitals increased, so did the cases of puerperal sepsis. The death rate from puerperal sepsis in Norway was high and remained so until 1934. Semmelweis studied the maternal mortality rates in two obstetric clinics in Vienna for the years 1841-46. He declared that puerperal fever was transmitted by the doctors who taught in the dissecting room and went straight from there into the labour wards. I 1847 he instructed all doctors or students to scrub their hands in a solution of chloride of lime before they delivered, examined or touched any patient. The haemolytic streptococcus was finally proved to be the cause of puerperal sepsis by Louis Pasteur in 1879. There was a significant drop in mortality rates in maternity hospitals after the introduction of antiseptic and aseptic techniques around 1880. Deaths from puerperal fever paralleled deaths from erysipelas, and both conditions declined after 1934. Puerperal fever and pelvic inflammation is still a clinical problem. The author discusses sexually transmitted diseases and multibacterial causes.

Asepsis↗

[Puerperal infection of ureaplasma urealyticum].

Using indirect agglutination test (IAT), ELISA and metabolic inhibition test (MI), serum specific IgM antibodies to ureaplasma urealyticum (Un) was investigated in 160 women of late pregnancy during the period of 1991-1992. 81 cases (50.6%) were found positive. 65 out of 81 positive mothers had umbilical blood samples examined and placenta tissues cultured. Specific IgM was detected in the umbilical blood of 7 women (10.8%), and ureaplasma urealyticum was isolated from 6 placenta (9.2%). Among Un IgM positive women, 28 (34.6%) were complicated with puerperal fever, and 30 newborns suffered from neonatal pneumonia and fever, which were significantly higher than that in the Un IgM negative group (P < 0.05). This study indicated that ureaplasma urealyticum might be one of the important pathogens for puerperal and neonatal infection.

Adult↗

[Puerperal infection of the urinary tract].

An urine routine and bacteriological analysis was performed in 100 female patients in third "trimester" of pregnancy and in the second day after delivery. When bacteriuria was detected a next urine bacteriological examination was done in 8-10 and 30-50 days after the delivery. A rate of bacteriuria in female patients before the delivery was 33% and after 56%. The results of routine urine analysis were in normal limits in 31.1% of females with significant bacteriuria. A spontaneous disappearance of bacteriuria between 8 and 50 day after the delivery was observed in 46.6% of patients, but in 53.4% symptoms of urinary tract infection were noticed. Escherichia coli (serotype A and B) was defined in 79.3% of observed urinary tract infections.

Adult↗

[Puerperal infections].

6 patients with serious wound infections and severe endomyometritis in the childbed were treated. Problems with early diagnosis of sepsis and of bacterial shock have been referred. Therapy has to consider early surgical intervention high dosage antibiotic treatment and early therapy of shock.

Adult↗