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PubMedDate not supplied

A comparison of pulpectomies using ZOE and KRI paste in primary molars: a retrospective study.

Maintaining a successfully root-treated primary molar has the advantage of preserving the natural tooth--the best possible space maintainer. The purpose of this study was to compare the success of endodontic treatment of nonvital primary molars using ZOE with that of KRI paste. Of 78 necrotic primary molars, 34 were filled with ZOE and 44 with an iodoform-containing paste (KRI). The canals were prepared with files, rinsed with saline and filled with one of the resorbable pastes, using a spiral Lentulo on a low-speed handpiece. A radiograph was exposed immediately postoperatively to observe whether the root filling was flush, underfilled, or overfilled. The effect of length of fill on the treatment outcome also was evaluated. Teeth were examined periodically clinically and radiographically to assess success of the treatment. Follow-up interval varied from 12 to more than 48 months. Overall success rate for KRI paste was 84% versus 65% for ZOE, which was statistically significant (P < 0.05). Overfilling with ZOE led to a failure rate of 59% as opposed to 21% for KRI (P < 0.02). Conversely, underfilling led to similar results, with a failure rate of 17% for ZOE and 14% for KRI. These results support the clinical efficacy of root filling with KRI paste as a treatment option for nonvital primary molars.

Camphor↗
PubMedDate not supplied

In vitro antimicrobial and cytotoxic effects of Kri 1 paste and zinc oxide-eugenol used in primary tooth pulpectomies.

The antimicrobial and cytotoxic effects of Kri 1 paste, an iodoform-based primary tooth filling material, were compared with zinc oxide-eugenol (ZOE), using in vitro techniques. Antimicrobial evaluation involved measuring inhibition zones of Streptococcus faecalis on brain heart agar. Cytotoxicity evaluation involved direct cell-medicament contact experiments of 4-hr and 24-hr duration using fresh and set medicaments, and indirect cell-medicament contact experiments of 24-hr duration using fresh and set medicaments. ZOE produced a greater zone of bacterial inhibition than Kri 1 paste. Kri 1 paste cytotoxicity remained high regardless of the amount of setting time in the 4-hr direct contact experiment, while ZOE cytotoxicity decreased with setting time. Both Kri 1 paste and ZOE had high cytotoxicity regardless of setting time in the 24-hr direct cell-medicament contact test. ZOE cytotoxicity decreased to control levels after only 1 day of setting in the indirect contact experiments, compared with greater than 7 days for Kri 1 paste. The results suggest ZOE has better antimicrobial activity than Kri 1 paste. ZOE also has lower cytotoxicity, although prolonged cell-medicament contact may result in both medicaments having similarly high cytotoxicity.

Analysis of Variance↗
PubMed1994

Timing of calcium hydroxide therapy in the treatment of root resorption in replanted teeth in dogs.

The effect of time of the onset of calcium hydroxide (CH) pulpectomy on root resorption of 31 permanent dog incisors was investigated. CH pulpectomy was delayed 4, 9, 14 and 18 days after the teeth were extracted and replanted. Control teeth were replanted 1) without pulpectomy, 2) with a pulpectomy only or 3) with a pulpectomy and CH filling. All teeth were prepared for histologic evaluation 8 weeks after the teeth were replanted. Cross section were examined using a computer microscope and linear (micron) and/or square areas (micron 2) of surface (SRR), inflammatory (IRR), and replacement (RRR) root resorption were calculated. From this data the percentage of linear and area resorption was averaged for each group. Duncan multiple range t-test (P < or = 0.05) revealed that teeth in which a pulpectomy with CH filling was done extraorally had significantly greater SRR than the rest of the groups; teeth in which a pulpectomy without CH filling was done extraorally had significantly greater RRR than teeth in which CH pulpectomy was delayed for 18 days; there was no significant difference in SRR, IRR or RRR when CH placement was delayed 4, 9, 14 or 18 days after replantation. Although it was not significant the overall resorption was least when CH pulpectomy was delayed 18 days.

Animals↗
PubMed2005

Synaptic contacts established by inferior alveolar nerve fibres in the paratrigeminal nucleus: an electron microscopic study in the rat.

A quantitative evaluation of the types of synaptic contacts from afferent fibres in the paratrigeminal nucleus after partial pulpectomy was compared with that after transection of the inferior alveolar nerve (IAN), using transganglionic degeneration. Degenerating terminals with a marked increase in axoplasmic electron opacity were observed bilaterally in the paratrigeminal nucleus of rats submitted to either partial pulpectomy or IAN transection. The total number of degenerating terminals observed after partial pulpectomy was 53% of that for IAN transection. This suggests a considerable contribution of tooth pulp afferent fibres in the total number of synaptic contacts in the intermediate and caudal parts of the paratrigeminal nucleus. In both the partial pulpectomy and IAN-transected groups, the majority of these synapses formed single asymmetric contacts with intermediate and distal dendritic segments, and accounted for 74% of all classified contacts. The remaining 26% of contacts occurred with proximal dendritic segments, dendritic spines, perikaryon, normal terminals and double post-synaptic elements. There was no statistically significant difference in the number of synaptic contacts for each type of synapse, with the exception of contacts with dendritic spines in the contralateral side, between the partially pulpectomised and IAN-transected groups.

Animals↗