PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Reproductive Medicine”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 145 records · Page 8Linked to original sources
PubMed2002

Biotechnology in reproductive medicine.

In this review I am summarizing the past and current progress in the field of pharmaceutical, diagnostic, therapeutic, and reproductive cloning in mammals. Several human gene products can be pharmaceutically explored in transgenic farm animals and employed for medical applications. Preimplantation genetic diagnosis (PGD) is utilizing modern molecular cloning techniques to detect genetic and chromosomal aberrations in early embryos originating from patients with inborn errors at risk for hereditary diseases or age-related risk for abnormal karyotype. Stem cell engineering from early human embryos is creating new and promising but also controversial applications for therapeutic and regenerative medicine. Potential risk factors for reproductive cloning are presented and discussed in the context of possible developmental malformations, frequently observed after embryo culture and cloning in farm animals. Future extension of biotechnology to human reproductive cloning is currently under worldwide dispute.

Animals↗
PubMed2003

Evaluating the medical literature in reproductive medicine: questions concerning prognosis.

To illustrate the recommended approach to questions concerning prognosis and the formulation of clinical recommendations, the principles of evidence-based medicine were applied to questions regarding the cardiovascular health risks associated with polycystic ovary syndrome (PCOS) and the effects of treatment on risk. A critical examination of the published literature reveals that the clinical diagnosis of PCOS does not, by itself, increase the risk of developing coronary heart disease (CHD) or adversely affect the prognosis in women with CHD. Rather, any increased risks can be attributed to other known risk factors (obesity, hypertension, diabetes, dyslipidemia) commonly observed in women with the disorder. Treatment strategies that decrease the probability of developing such co-morbid conditions (diet, exercise) or are effective in their management (antihypertensives, statins, insulin-sinsitizing agents) may be expected to reduce risk or improve prognosis, but available evidence is insufficient to warrant a general recommendation for metformin treatment as a CHD risk reduction strategy in all women with PCOS.

Adult↗
PubMed2001

Cloning in reproductive medicine.

This review article summarizes the historical development of mammalian cloning, presents current advances and presumed risk factors in the field of reproductive cloning, discusses possible clinical applications of therapeutic and diagnostic cloning and outlines prospective commercial trends in pharmaceutical cloning. Predictable progress in biotechnology and stem cell engineering should prove to be advantageous for patients' health and for novel benefits in reproductive and regenerative medicine.

Animals↗
PubMed1998

[Bioethical aspects of reproductive medicine].

Based on the FIGO recommendations of 1997, the Authors discuss selected bioethical problems associated with procreational medicine. Paper reviews published opinions of both medical and non-medical world including those stated by Council of Europe.

Ethics, Medical↗