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En bloc excision of lower ureter and internal iliac vessels for locally advanced upper rectal and rectosigmoid cancer. Use of ileal segment for ureteral repair.

Eight patients who received en bloc excision of the ureter and internal iliac vessels for locally advanced upper rectal and rectosigmoid cancer were reported. Indications, techniques, functional results of the ileal ureter, and prognosis of these patients are discussed. Although three patients died of recurrent tumor--one of transperitoneal spread and two of liver metastasis--none of them developed local recurrent growth. As a replacement for the resected ureter, ileal substitution was applied in all eight patients--unilateral in six patients and bilateral in two. Serum creatinine and electrolyte patterns were within the normal range in all patients. A voiding cystogram showed no reflux to the anastomosed ureter, and a mild reflux to the ileal segment. The patients had excellent prognoses with regard to local control and also satisfactory functional results with the ileal ureter. The authors recommend that this procedure be applied to patients with locally advanced cancer such as those in this series.

Adult↗

A postmortem appraisal of a clinicopathologic staging system in large-bowel cancer.

The autopsy findings of 100 patients who had a resection for large-bowel cancer and who were classified by a clinicopathologic staging system were analyzed. Seventy patients had carcinoma at autopsy. The value of this method of staging was assessed by relating the stage at operation to these findings. Forty-five per cent of early stage tumors (A or B) were found to have metastases. If the detection rate of occult metastases could be improved for stage A and B tumors, this might increase the prognostic accuracy of this staging system.

Autopsy↗

The diagnosis of colorectal cancer with cytologic brushings under direct vision at fiberoptic colonoscopy. A report of 59 cases.

Fifty nine cases of colorectal cancer confirmed postoperatively by histologic examination were correlated with the findings of biopsy specimens and cell brushings. Fifty one cases were positive for malignancy on biopsy (86.4 percent). Brush cytology was positive in 51 cases (86.4 percent). The total preoperative confirmed diagnostic rate of the series was 91.5 percent. Brushing cytology under direct vision at fiberoptic colonoscopy, is a safe, reliable, and quite accurate method for the diagnosis of colorectal cancer. The results from brush cytology did not relate to the configuration and appearance of the tumor. For cell brushing, the fluid in the colonic lumen should be aspirated off as thoroughly as possible. Cell brushings are often positive when colonic stricture and obstruction prevent the colonoscope from reaching the lesion; biopsy, obviously, cannot be done in such a case.

Adolescent↗

Diffuse cavernous hemangioma of the rectosigmoid--CT scan, a new diagnostic modality, and surgical management using sphincter-saving procedures. Report of three cases.

Diffuse cavernous hemangioma of the rectosigmoid is a rare lesion. Preoperative recognition has been recorded but, because of lack of awareness and inconsistent diagnoses, inappropriate therapy still persists. Surgical therapy is the hallmark of treatment. Abdominoperineal resection has been advocated. Three cases of diffuse cavernous hemangiomas of the rectosigmoid, recognized preoperatively and treated successfully with sphincter-saving procedures, are reported. Use of the CT scan as a consistent diagnostic tool will be presented for the first time.

Adult↗

Management of colostomal hemorrhage resulting from portal hypertension.

Colostomy and ileostomy stomal hemorrhage is a rare and potentially fatal complication of portal hypertension. We describe two patients with colostomy stomal hemorrhage who had both undergone abdominoperineal resection for carcinoma of the rectosigmoid colon. Patient 1, in the absence of metastatic disease with minimal to moderate functional hepatic impairment, undersent a mesocaval interposition graft shunt and had no recurrence of stomal hemorrhage during the four-month postoperative period. Patient 2, in the presence of metastatic disease to the lungs and liver, was not shunted and died of hepatic and renal failure. Angiography, in particular splenoportography, is extremely helpful in establishing the diagnosis of portal hypertension and planning appropriate operative procedure. We reviewed the literature on ileostomy and colostomy hemorrhage in the presence of portal hypertension and conclude that control of major stomal hemorrhage by local measures is often ineffective and that portasystemic shunts may significantly improve long-term prognosis.

Adenocarcinoma↗

Changing site distribution patterns of colorectal cancer at Thomas Jefferson University Hospital.

Analyzed data from an earlier reported experience with colorectal cancer at Thomas Jefferson University Hospital, compared with findings observed and analyzed from 1959 to 1977 indicate a changing pattern of distribution of colorectal cancers. These changes lead to therapeutic conclusion that fiberoptic flexible sigmoidoscopy is the preferred diagnostic tool.

Colonic Neoplasms↗