PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Suction”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 145 records · Page 8Linked to original sources

Suctioning through a double-lumen endotracheal tube helps to prevent alveolar collapse and to preserve ventilation.

OBJECTIVE: Endotracheal suctioning can cause alveolar collapse and impede ventilation. One reason is the gas flow through a single-lumen endotracheal tube (ETT) provoking a gradient between airway opening and tracheal (P(tr)) pressures. Separately extending the patient tubing limbs of a suitable ventilator into the trachea via a double-lumen ETT should maintain P(tr). Can this technique reduce the side effects? DESIGN AND SETTING: Bench and animal studies in a university hospital laboratory. INTERVENTIONS: A lung model was ventilated via single and double-lumen ETTs. Closed-system suctioning was applied with catheters introduced into the single-lumen ETT or the expiratory lumen of the double-lumen ETT via swivel adapter. Seven anesthetized pigs (lungs lavaged) underwent three runs of ventilation and suctioning through (a, b) an 8.0-mm ID single-lumen ETT, (c) a double-lumen ETT (41Ch outer diameter, OD). In (a) the single-lumen ETT was disconnected for suctioning, in (b) and (c) ventilator mode was set to continuous positive airway pressure mode, and the ETTs remained connected. MEASUREMENTS AND RESULTS: Bench: Suction through single-lumen ETTs impaired ventilation and led to strongly negative P(tr) (common: -10 to -20 mbar); the double-lumen ETT technique maintained ventilation and pressures. ANIMALS: Lung gas content (computed tomography, n=4) and arterial oxygen partial pressure, initially 1462+/-65 ml/532+/-76 mmHg, were significantly reduced by suctioning through single-lumen ETT: to 302+/-79 ml/62+/-6 mmHg with disconnection and to 851+/-211 ml/158+/-107 mmHg with closed suction. With double-lumen ETT they remained at 1377+/-95 ml/521+/-56 mmHg. CONCLUSIONS: The double-lumen ETT technique minimizes side effects of suctioning by maintaining P(tr).

Animals↗

Wall or machine suction rectal biopsy for Hirschsprung's disease: a simple modified technique can improve the adequacy of biopsy.

Suction rectal biopsy (SRB) may not include sufficient submucosa for histological diagnosis of Hirschsprung's disease (HD) and a repeat biopsy is required. Substitution of the conventional syringe for sustained suction from a machine or wall suction unit could provide a more consistently adequate tissue biopsy. This study was conducted to compare the adequacy of SRB specimens using a conventional method of syringe suction (SSRB) with those taken by wall or machine suction (WSRB). Hospital records of patients who had a SRB between 2002 and 2004 were studied retrospectively. The biopsy was considered inadequate if there was insufficient submucosa and a repeat specimen was requested. SSRB were taken using the conventional SSRB technique. WSRB were taken with the same Noblett forceps but with suction from wall suction or from a portable suction machine. Ninety-five infants had 103 SRB, 24 had WSRB and all (100%) were adequate for histopathological diagnosis or exclusion of HD. Seventy nine conventional SSRB were undertaken in 71 infants of which 64 (81.02%) were adequate. The difference in adequacy between WSRB and SSRB was statistically significant (P = 0.02). There were no instances of haemorrhage or bowel perforation in either subgroup. WSRB with the Noblett biopsy forceps is more likely to produce an adequate specimen and to reduce the incidence of repeat biopsies.

Biopsy↗

Experimental observation of intraocular pressure changes during microkeratome suctioning in laser in situ keratomileusis.

PURPOSE: To observe changes in intraocular pressure (IOP), the manner in which the eye is suctioned, and the effect of the number of suction ports. SETTING: Department of Ophthalmology, Tokyo Dental College, Suidobashi Hospital, Tokyo, Japan. METHODS: Suction rings with single or dual ports were made of transparent acrylic acid resin to facilitate observation with a digital video camera. The IOP and the duration of the IOP increase (time to reach 90% of the maximum IOP) were measured in 6 porcine eyes with an intra-vein pressure-sensor catheter in the vitreous cavity. The IOP changes were recorded using a personal computer. RESULTS: Suctioning with single- and dual-port suction rings was similar. The IOP increases with single- and dual-port suction rings were similar (99.1 mm Hg +/- 6.1 [SD] and 99.0 +/- 6.5 mm Hg, respectively) (P=.987). The duration of the IOP increase was also similar (4.21 +/- 0.24 seconds and 4.12 +/- 0.33 seconds, respectively) (P=.190). CONCLUSIONS: The number of ports did not affect suctioning and changes in IOP. This technique is useful in developing the ideal shape and setting of the suction ring.

Animals↗

Bacterial contamination of dental chair units in a modern dental hospital caused by leakage from suction system hoses containing extensive biofilm.

Within six months of opening of the new Dublin Dental Hospital in September 1998, areas of corrosion were observed on many of the baseplates of the hospital's 103 dental chair units (DCUs) at the site of attachment of the suction hoses. The corroded areas were heavily contaminated with Pseudomonas spp. and related genera posing a risk of cross-infection, particularly for immunocompromised patients. These species were used as marker organisms to investigate the source of the contamination. P. aeruginosa was the predominant species recovered from 41 selected DCU baseplates (61% prevalence), whereas P. putida (46% prevalence) and P. aeruginosa (43% prevalence) were predominant at the attachment ends of 37 selected high-volume suction hoses. Forty-one selected isolates of P. aeruginosa from 13 DCU baseplates, 16 high-volume suction hoses and 12 coarse filter housings (another suction system site) from 19 separate DCUs were serotyped to determine the similarity of isolates at each site. The majority of isolates (68.3%) belonged to serotype O:10, while the remainder belonged to serotypes O:6 (7.3%), O:11 (7.3%), O:14 (9.8%) and O:5/O:16 (7.3%). Of the isolates from DCU baseplates, additional isolates with the same serotype were recovered from other suction system sites in 10/13 (77%) cases. Isolates of only one serotype were recovered from each of the 19 DCUs investigated. Forty-one serotyped isolates were also subject to computer-assisted analysis of SpeI-generated DNA fingerprint profiles, and similarity coefficient (S(AB)s) values were calculated for each pairwise combination of isolate profiles. The data obtained showed that the isolates consisted of two distinct main populations, each containing separate clades corresponding to specific serotypes. Serotype O:6 (three isolates), O:11 (three isolates) and O:5/O:16 (three isolates) belonged to a single strain in each case. Serotypes O:14 (four isolates) and O:10 (28 isolates) belonged to two strains in each case. The two serotype O:10 strains, termed fingerprint groups I (four isolates from three DCUs) and II (24 isolates from 10 DCUs), were the most distantly related of all the strains identified. These findings demonstrated that the hospital DCUs had become colonized with a small number of P. aeruginosa strains, one of which (serotype O:10, fingerprint group II) predominated. These results also confirmed that DCU baseplate contamination was most likely to be due to leakage from suction system hoses at the baseplate attachment sites, probably due to loosening during use. Replacement hose connectors that firmly retained the suction hoses in the attachment sites so that they could not be loosened by movement of the suction hoses solved this problem, and eliminated further contamination of the DCU baseplates.

Biofilms↗

The effect of suction catheter insertion and tracheal stimulation in adults with severe brain injury.

OBJECTIVE: To determine the effect of suction catheter insertion and tracheal stimulation on cerebrovascular and systemic vascular status in adults with severe traumatic brain injury. DESIGN: Quasi-experimental, within-subject design. SETTING: Two university-affiliated critical care units. SUBJECTS: Thirty intubated and mechanically ventilated adults with severe brain injury. The participants' average age was 31 +/- 15 years. OUTCOME MEASURES: Mean intracranial pressure (MICP), mean arterial pressure (MAP), cerebral perfusion pressure (CPP), and heart rate (HR) were measured. INTERVENTION: Endotracheal suction catheter insertion with tracheal stimulation was performed. RESULTS: Suction catheter insertion and tracheal stimulation, isolated from other components of the suctioning procedure, significantly increased MICP, MAP, and CPP. HR was not significantly increased. During the application of negative pressure for actual suctioning, MICP and HR significantly increased, whereas MAP and CPP did not significantly change compared with catheter insertion. CONCLUSION: Tracheal stimulation during suction catheter insertion initiates both cerebrovascular and systemic vascular responses during the suctioning procedure. Study findings suggest that a potentially productive direction for intervention research is to identify ways to minimize airway stimulation during the suctioning procedure.

Adult↗

Smart suction device for less blood trauma: a comparison with Cell Saver.

OBJECTIVE: The major source of hemolysis during cardiopulmonary bypass remains the cardiotomy suction and is primarily due to the interaction between air and blood. The Smart suction system involves an automatically controlled aspiration designed to avoid the mixture of blood with air. This study was set-up to compare this recently designed suction system to a Cell Saver system in order to investigate their effects on blood elements during prolonged intrathoracic aspiration. METHODS: In a calf model (n=10; mean weight, 69.3+/-4.5 kg), a standardized hole was created in the right atrium allowing a blood loss of 100 ml/min, with a suction cannula placed into the chest cavity into a fixed position during 6 h. The blood was continuously aspirated either with the Smart suction system (five animals) or the Cell Saver system (five animals). Blood samples were taken hourly for blood cell counts and biochemistry. RESULTS: In the Smart suction group, red cell count, plasma protein and free hemoglobin levels remained stable, while platelet count exhibited a significant drop from the fifth hour onwards (prebypass: 683+/-201*10(9)/l, 5 h: 280+/-142*10(9)/l, P=0.046). In the Cell Saver group, there was a significant drop of the red cell count from the third hour onwards (prebypass: 8.6+/-0.9*10(12)/l, 6 h: 6.3+/-0.4*10(12)/l, P=0.02), of the platelet count from the first hour onwards (prebypass: 630+/-97*10(9)/l, 1 h: 224+/-75*10(9)/l, P<0.01), and of the plasma protein level from the first hour onwards (prebypass: 61.7+/-0.6 g/l, 1 h: 29.3+/-9.1 g/l, P<0.01). CONCLUSIONS: In this experimental set-up, the Smart suction system avoids damage to red cells and affects platelet count less than the Cell Saver system which induces important blood cell destruction, as any suction device mixing air and blood, as well as severe hypoproteinemia with its metabolic, clotting and hemodynamic consequences.

Animals↗

[Assessment of practice competence and scientific knowledge of ICU nurses in the tracheal suctioning].

Tracheal suctioning is essential to maintain permeability of the artificial airway. This procedure may be associated to risks for the patients. Thus, it is very important to know if the nurses perform it correctly and if the practice is based on scientific evidence. This investigations objectives are: evaluate practical competence of the nurses, as well as the scientific knowledge that they have on this procedures in a Polyvalent Intensive Care Unit and analyze if there are discrepancies between the practice competence and scientific knowledge. This descriptive study, performed in 34 nurses, analyzed the performance of tracheal suctioning by direct observation, using the data collection of a structured grid that included 19 aspects to evaluate, grouped into 6 categories. In the same way, knowledge on the procedure was analyzed, using a 19-item self-administered questionnaire, also grouped into 6 categories, which evaluated the same aspects observed. The total mean score obtained in the practice observation grid (P) was 12.09 for a maximum score of 19, while it was 14.24 in the knowledge questionnaire (Q). When analyzed by categories, discrepancies were obtained in the following aspects: in the need for hand washing prior to suctioning (P = 55.9%; Q = 97.1%), in cleaning of the suction catheter after each suctioning during the procedure (P = 0%; Q = 38.2%), in the correct performance of hyperoxygenation and hyperinsuflation, before, during and after the procedure (P = 11.8%; Q = 941%), in the correct selection of the size suction catheter in relationship with endotracheal tubes internal lumen (P = 0%; Q = 52.9%), in the maximum time the catheter remains in the trachea (P = 100%; Q = 23.5%), in the maximum number of times that the catheter should be introduced in each suctioning (P = 100%; Q = 73.5%) and in the non-instillation of saline solution (P = 29.4%; Q = 58.8%). When the total scores obtained were compared, both in practice and knowledge, with the years of experience in ICU, no statistically significant differences were found. It is concluded that the study nurses have scientific knowledge of the suctioning procedure that are better than their practice competence. Discrepancies between practice and knowledge were also found in several of the aspects evaluated, which orients towards the specific needs of training in this procedure.

Adult↗

Effects of normal saline on endotracheal suctioning.

This study was designed to determine the effects of saline solution administered prior to endotracheal suctioning by nurses working in intensive care on oxygenation, heart rate and long-term pulmonary hygiene. The study was carried out on an experimental basis in the Intensive Care Unit of a university hospital in Turkey. A total of 20 patients were included, who were mechanically ventilated because of pulmonary or cardiovascular problems or trauma. Data were collected using a data form. Each patient was monitored for 5 minutes following suctioning with or without saline solution and findings of heart rate, SpO2, and blood gas measurements were recorded. Data were analysed using percentage calculations, the student's t-test and the Friedman test. The study showed that most of the patients were between 60 and 69 years and were intubated because of respiratory insufficiency. Evaluation of blood gases following suctioning with or without saline solution showed partial decreases in pO2, pCO2, HCO3, and oxygen saturation (SaO2), which did not reach a significant level. No significant difference was found between pH levels recorded prior to and 5 minutes after suctioning without saline solution; however, the increase in pH following suctioning with saline solution was significant. Patients undergoing suctioning with saline solution exhibited significantly increased heart rates in the fourth and fifth minutes, whereas no increases were detected in these undergoing suctioning without saline solution. SpO2 values obtained by pulse oxymeter did not show significant differences. Saline solution administered with suctioning resulted in undesirable, although not significant, alterations in oxygen saturation and arterial blood gas levels.

Adult↗

Suction device for epidermal grafting in vitiligo: employing a syringe and a manometer to provide an adequate negative pressure.

BACKGROUND: Suction devices for epidermal grafting need a suction pump to provide a negative pressure. The authors have developed a suction device in which a syringe and a manometer are employed to provide a negative pressure. OBJECTIVE: The purpose of this study was to evaluate the efficacy of our suction device in vitiligo patients. METHODS: The suction device was used to obtain epidermal blisters from the donor site. A CO2 laser was employed to remove the depigmented epidermis. The blister roofs of the donor site were harvested and were placed onto the recipient area. Ten patients with stable vitiligo were treated by epidermal grafting. RESULTS: Epidermal blisters were produced by suction in all patients. Also, all 10 patients regained repigmentation. CONCLUSION: Our suction blister device is simple and inexpensive to make, and it may become an alternative to the other suction devices.

Adolescent↗

Suction blister induction time: 15 minutes or 150 minutes?

BACKGROUND: The literature on suction blister is somewhat confusing regarding suction blister induction time (SBIT). To date, various factors influencing the SBIT have not been discussed comprehensively. OBJECTIVE: To determine the effect of diameter of suction syringes/cups on SBIT and review the factors influencing SBIT. METHODS: Five young patients (four females, one male; age range 16-27 years, average age 23 years) were selected for the study. Five suction syringes of 2, 5, 10, 20, and 50 ml capacity (diameter 1, 1. 4, 1.7, 2.2, and 3.2 cm, respectively) were applied on the lateral aspect of the thigh and observed for production of unilocular blister at 15 minute intervals. RESULTS: The average SBIT was 63, 72, 98, 123, and 208 minutes in 2, 5, 10, 20, and 50 ml syringes, respectively. CONCLUSIONS: The SBIT is directly proportional to the diameter of the suction syringe. A literature review suggests that the site of the suction blister, age of the subject, amount of vacuum created, temperature, intradermal injection of saline, corticosteroid-induced atrophy, and pretreatment of the site with PUVA are the important factors influencing the SBIT. Use of 10 or 20 ml syringes as suction cups and -300 mmHg pressure are appropriate choices for suction blister induction and produce blisters in about 1-2 hours.

Adolescent↗

The standard of suction for patients undergoing endotracheal intubation.

The purpose of this study was to determine whether using a standard method of endotracheal suctioning, to ensure consistent use of available knowledge, had any impact on patient care. Using experimental study design, the results of two different methods of suctioning in a cardiovascular surgery intensive care unit were compared. One method was the suctioning procedure applied by the nurses working in the intensive care unit. The other one, standard suctioning procedure, was developed based on the related literature and applied to the patients assigned to the experimental group by the researcher herself. Mean arterial blood pressure (MAP), heart rate (HR), and arterial blood gases (ABGs) were measured before the procedure, immediately after, 5 and 15 minutes after the procedures for both control and experimental group. The majority of the nurses suctioning the control group did not evaluate the ABGs after endotracheal suctioning, none of these patients was given oxygen both before and after the suctioning, and suctioning took longer time than recommended. To compare the results of the two different methods, the values of MAP, HR, PO2 (arterial oxygenation), PCO2 (arterial carbondioxide), and HCO3- (hydrogen carbonate) 15 minutes after the procedure were used, and the differences between the two methods were statistically significant (P < 0.05).

Blood Gas Analysis↗

Level of dyspnoea experienced in mechanically ventilated adults with and without saline instillation prior to endotracheal suctioning.

The purpose of this study was to compare the level of dyspnoea with and without the use of 5-cc saline instillation prior to endotracheal suctioning of mechanically ventilated adults. A crossover, quasi-experimental design was used. Seventeen alert, mechanically ventilated adults were asked to rank their level of dyspnoea using the vertical visual analogue scale at specific time intervals surrounding two suctioning events. Saline was randomly assigned to be instilled prior to one of two suctioning episodes. Dyspnoea was ranked immediately after suctioning, and at 10-, 20-, and 30-minute intervals. Data were analyzed using repeated measures analysis of variance with time of measure (immediately after suctioning, 10-, 20-, and 30-minute intervals) and treatment type (with saline versus without saline instillation). The level of dyspnoea based on treatment type (with or without saline) was non-significant. Treatment type by age group interaction was significant (F(1, 15) = 5.41, P = 0.034). The nature of the interaction revealed that older patients (< or = 60 years of age) experienced less dyspnoea without saline prior to suctioning and greater dyspnoea with saline instillation as compared to the younger subjects (<60 years of age). This study documented no beneficial effects of saline. However, it did demonstrate that saline instillation might precipitate a significantly increased level of dyspnoea for up to 10 minutes after suctioning in patients older than 60 years of age. Recommendations based on the results of this study would be to avoid the use of saline instillation prior to suctioning.

Adult↗

[Comparison of effects of endotracheal suction and surfactant administration on hemodynamics and oxygenation of premature infants--a near infrared spectroscopy study].

BACKGROUND: Aim of this study was to assess whether the decrease in heart rate and oxygen saturation occurring acutely after bolus administration of surfactant is different from the effect of endotracheal suctioning and whether there are effects on cerebral haemodynamics and oxygenation. METHODS: Twelve premature infants, birth weight 720-1560 g (Median 935 g), gestational age 25-30 weeks (Median 28 weeks), were investigated during surfactant administration (Curosurf) as a single bolus and a preceding endotracheal suctioning procedure. Using near infrared spectroscopy changes in cerebral blood volume and cerebral oxygenation index were assessed. Heart rate, arterial oxygen saturation, PCO2, and arterial blood pressure were registered continuously. Data were compared at 30, 60 and 120 seconds after the beginning of suctioning and surfactant administration. RESULTS: Endotracheal suctioning and surfactant administration induced a similar decrease in heart rate (-29/min, SD 25, p < 0.01 and -30/min, SD 23, p < 0.001) during the first 30 seconds and in oxygen saturation at the 30 seconds datapoint (-3%, SD 2, p < 0.01 and -3%, SD 6, p < 0.05). The decrease in oxygen saturation persisted at 60 seconds after the start of suctioning (-4%, SD 5, p < 0.05). In contrast, oxygen saturation was no longer different from baseline levels 60 seconds after surfactant administration (+1%, SD 6, p = 0.5). After suctioning, cerebral oxygenation index had decreased significantly from baseline levels at 30, 60, and 120 seconds. In contrast, after surfactant administration, no significant difference from baseline was noted at 30 and 60 seconds and a significant increase occurred at 120 seconds. Mean arterial blood pressure, PCO2, and cerebral blood volume did not change significantly during endotracheal suctioning and during surfactant administration. CONCLUSIONS: Acute decreases in heart rate and oxygen saturation during bolus administration of surfactant are equal to effects occurring during endotracheal suctioning. However, the decrease in oxygen saturation is shorter and more importantly, no decrease in cerebral oxygenation occurs.

Biological Products↗

Efficacy of bulb versus DeLee suction at deliveries complicated by meconium stained amniotic fluid.

A combined obstetric-pediatric approach to the management of deliveries complicated by meconium-stained amniotic fluid has been recommended to decrease the incidence of meconium aspiration syndrome. Although pharyngeal suction with a DeLee catheter is generally recommended, many obstetricians prefer to use a bulb syringe for suction at the perineum. A thorough review of the literature reveals no prospective studies in humans comparing the two techniques. In the present study, these two techniques of pharyngeal suction were prospectively compared at deliveries complicated by meconium-stained amniotic fluid. Of the total 2874 deliveries, 127 (4%) were complicated by moderate or thickly meconium-stained amniotic fluid, and 107 of these were included in the study. There were 53 infants in the DeLee-suctioned group and 54 in the bulb-suctioned group. Of the 107 studied infants, four (4%) developed meconium aspiration syndrome, three in the DeLee group and one in the bulb group. There was no significant difference in the amount of meconium found below the vocal cords, comparing pharyngeal DeLee suction to bulb suction (0.22 cc versus 0.24 cc; p = NS). In conclusion, the data fail to support a significant difference in efficacy between bulb and DeLee suction in clearing the naso- and oropharynx of the neonate of meconium in cephalic-presenting vaginal or cesarean delivery.

Adult↗

Effects of endotracheal suction versus apnea during interruption of intermittent or continuous positive pressure ventilation.

The hypoxemia, elevated vascular pressure, and cardiac arrhythmias occurring during endotracheal suction may be related both to suction and the interruption of ventilation during suction. Although effects of suction vs. apnea have been compared in healthy patients, interruption of ventilation for purely investigational purposes precludes such a study in critically ill patients. Thus, in the present study, cardiovascular and blood gas changes attendant to endotracheal suction or equivalent periods of apnea were compared in anesthetized, paralyzed dogs in acute respiratory failure induced by oleic acid. Suction of 45-sec duration during interruption of intermittent positive pressure ventilation (IPPV) was associated with decreases in PaO2, pH, and heart rate and increases in PaCO2, cardiac output, pulmonary arterial and systemic arterial pressure. These changes were not different from those observed during interruption of ventilation (apnea) alone. Cardiovascular and blood gas changes were also similar when suction and apnea were compared during interruption of continuous positive pressure ventilation (CPPV). Neither apnea nor suction was associated with cardiac arrhythmias.

Animals↗

Prevention of suction-induced gastric mucosal damage in dogs.

Gastric suction has traditionally been available in three modes: continuous, sump, and intermittent. An intermittent air injection suction system (IAIS) has been developed in which small (20 to 30 mm) amounts of air are injected two to three times a minute. Very low (20 mm Hg) suction levels are applied. The hypothesis of the present study is that such a device will prevent suction-induced gastric mucosal damage, probably produced by suctioning of mucosa into the holes of the NG tube. IAIS should prevent this by physically expelling the mucosa out of the holes and allowing use of much lower suction levels. In 25 animals, gastric suction for 24 h in anesthetized dogs routinely produced ulcers. However, IAIS produced significantly fewer ulcers and in fewer animals. In 37 animals, the effectiveness of suction, measured by recovery of fluid instilled in the stomach, and the tendency of the tube to block were studied. Effectiveness was the same for all modes studied. Blockage was significantly less with IAIS.

Air↗

Cardiopulmonary and intracranial pressure changes related to endotracheal suctioning in preterm infants.

Although endotracheal (ET) suctioning is performed frequently in sick newborn infants, its effects on cardiorespiratory variables and intracranial pressure (ICP) have not been thoroughly documented in neonates greater than 24 h who were not paralyzed while receiving mechanical ventilation. This study evaluates these changes in preterm infants who required ventilatory assistance. We measured transcutaneous PO2 and PCO2 (PtcO2 and PtcCO2, respectively), intra-arterial BP, heart rate, ICP, and cerebral perfusion pressure (CPP) before, during, and for at least 5 min after ET suctioning in 15 low birth weight infants less than 1500 g and less than or equal to 30 days of age. One infant was studied twice. A suction adaptor was used to avoid disconnecting the patient from the ventilator and to attempt to minimize hypoxemia and hypercapnia during suctioning. The patients were studied in the supine position and muscle relaxants were not used. PtcO2 decreased 12.1% while PtcCO2 increased 4.7% 1 min after suctioning; however, greater increases in mean BP (33%) and ICP (117%) were observed during suctioning. CPP also increased during the procedure. ICP returned to baseline almost immediately, whereas BP remained slightly elevated 1 min after suctioning. Our findings demonstrate that ET suctioning significantly increases BP, ICP, and CPP in preterm infants on assisted ventilation in the first month of life. These changes appear to be independent of changes observed in oxygenation and ventilation.

Blood Pressure↗

Effect of suction on specimen size in fine-needle aspiration biopsy.

High incidences of unsatisfactory specimens in fine-needle aspiration biopsy for cytology have been reported previously. Inappropriate aspiration techniques may account partly for this. In this study, the effect of suction on specimen size was studied in vitro using an automatic sampler. Bovine liver, testis, and pig's kidney were used as target tissues and biopsies were performed with 18-, 20- and 22-gauge needles. Specimen weight increased rapidly and linearly with suction force (P less than .001), regardless of the target tissue or needle diameter, when standard needle movement was applied. In the absence of needle movement, the suction force, rate of increase of suction, and duration of suction had no effect on the weight of the specimens. Needle movement alone, without suction, also produced meager specimens. Suction alone does not seem to tear fragments off target tissues. Nevertheless, in combination with needle movement, suction force plays an important role in the determination of specimen size.

Animals↗