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Results for “VESTIBULAR APPARATUS”

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At least 145 records · Page 8Linked to original sources
PubMed1992

[Evaluation of the ear and vestibular apparatus depending on the anatomy of the cervical spine].

Function of the acoustic organ and the vestibular organ in correlation from radiograph of cervical spinal column was examined in 102 patients aged 20-68 years, of both sexes. The obtained results of audiometric and electronystagmographic investigations have shown that the greatest disorders of function of the acoustic organ and the vestibular organ was at the patients with osteophytes and discopathy in cervical spinal column. Impaired hearing and vestibular disorders was observed also at the patients with normal radiograph of cervical spinal column. The authors have thought that the above deviations can be caused by irritation even the discreet degeneration of cervical spinal column, which ones conduct to increased tension of sympathetic system.

Adult↗
PubMedDate not supplied

[Receptor epithelium of the vestibular apparatus and cochlea in exposure to acceleration and noise].

The method for isolating and treating the vestibular and cochlear compartments of the inner ear was developed. Also, the procedure of histological treatment of temporal bones was modified. The pathogenesis of vestibulo-cochlear disorders due to acceleration and noise was investigated using histology, electron microscopy and histochemistry methods. It was found that exposure to acceleration of 10 Gx for 5 min and single and repeated (for 7 days) exposures to high-frequency noise of 100 dB produced histological changes and functional-morphological variations in all receptors located in the vestibular and cochlear compartments of the inner ear.

Acceleration↗
PubMed2006

Dlx5 and Dlx6 homeobox genes are required for specification of the mammalian vestibular apparatus.

The mammalian inner ear is a complex organ that develops from a surface ectoderm into distinct auditory and vestibular components. Congenital malformation of these two components resulting from single or multiple gene defects is a common clinical occurrence and is observed in patients with split hand/split foot malformation, a malformation which is phenocopied by Dlx5/6 null mice. Analysis of mice lacking Dlx5 and Dlx6 homeobox genes identified their restricted and combined expression in the otic epithelium as a crucial regulator of vestibular cell fates. Otic induction initiates without incident in Dlx5/6(-/-) embryos, but dorsal otic derivatives including the semicircular ducts, utricle, saccule, and endolymphatic duct fail to form. Dlx5 and Dlx6 seem to influence vestibular cell fates by restricting Pax2 and activating Gbx2 and Bmp4 expression domains. Given their proximity to the disease locus and the observed phenotype in Dlx5/6 null mice, Dlx5/6 are likely candidates to mediate the inner ear defects observed in patients with split hand/split foot malformation.

Animals↗
PubMed1990

[The effect of adequate stimulation of the vestibular apparatus on evoked rhythmic activity in the nerves of the forelimbs in the immobilized guinea pig].

The influence of adequate vestibular stimulation on the rhythmical activity of forelimb nerves evoked by electrical stimulation of the mesencephalic locomotor region in combination with DOPA administration was registered in an immobilized guinea pig. Rhythmical activity was mainly registered in the flexor nerve. Intensity of the activity changed with animal tilting, decreasing during an ipsilateral incline and increasing during a contralateral one. These changes revealed a phase lag of -110 divided by -150 degrees relative to angular acceleration during cyclic tilting about a longitudinal axis with frequencies of 0.02-0.4 Hz.

Animals↗