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Recognition of motor imagery electroencephalography using independent component analysis and machine classifiers.

Motor imagery electroencephalography (EEG), which embodies cortical potentials during mental simulation of left or right finger lifting tasks, can be used to provide neural input signals to activate a brain computer interface (BCI). The effectiveness of such an EEG-based BCI system relies on two indispensable components: distinguishable patterns of brain signals and accurate classifiers. This work aims to extract two reliable neural features, termed contralateral and ipsilateral rebound maps, by removing artifacts from motor imagery EEG based on independent component analysis (ICA), and to employ four classifiers to investigate the efficacy of rebound maps. Results demonstrate that, with the use of ICA, recognition rates for four classifiers (fisher linear discriminant (FLD), back-propagation neural network (BP-NN), radial-basis function neural network (RBF-NN), and support vector machine (SVM)) improved significantly, from 54%, 54%, 57% and 55% to 70.5%, 75.5%, 76.5% and 77.3%, respectively. In addition, the areas under the receiver operating characteristics (ROC) curve, which assess the quality of classification over a wide range of misclassification costs, also improved from .65, .60, .62, and .64 to .74, .76, .80 and .81, respectively.

Adult↗

Learning from neural control.

One of the amazing successes of biological systems is their ability to "learn by doing" and so adapt to their environment. In this paper, first, a deterministic learning mechanism is presented, by which an appropriately designed adaptive neural controller is capable of learning closed-loop system dynamics during tracking control to a periodic reference orbit. Among various neural network (NN) architectures, the localized radial basis function (RBF) network is employed. A property of persistence of excitation (PE) for RBF networks is established, and a partial PE condition of closed-loop signals, i.e., the PE condition of a regression subvector constructed out of the RBFs along a periodic state trajectory, is proven to be satisfied. Accurate NN approximation for closed-loop system dynamics is achieved in a local region along the periodic state trajectory, and a learning ability is implemented during a closed-loop feedback control process. Second, based on the deterministic learning mechanism, a neural learning control scheme is proposed which can effectively recall and reuse the learned knowledge to achieve closed-loop stability and improved control performance. The significance of this paper is that the presented deterministic learning mechanism and the neural learning control scheme provide elementary components toward the development of a biologically-plausible learning and control methodology. Simulation studies are included to demonstrate the effectiveness of the approach.

Algorithms↗

EEG source localization: comparative study of classical and neural network methods.

We address the problem of estimating biopotential sources within the brain, based on EEG signals observed on the scalp. This problem, known as the inverse problem of electrophysiology, has no closed-form solution, and requires iterative techniques such as the Levenberg-Marquardt (LM) algorithm. Considering the nonlinear nature of the inverse problem, and the low signal to noise ratio inherent in EEG signals, a backpropagation neural network (BPN) has been recently proposed as a solution. The technique has not been properly compared with classical techniques such as the LM method, or with more recent neural network techniques such as the Radial Basis Function (RBF) network. In this paper, we provide improved strategies based on BPN and consider RBF networks in solving the inverse problem. We compare the performances of BPN, RBF and a hybrid technique with that of the classical LM method.

Brain↗

A novel preformulation tool to group microcrystalline celluloses using artificial neural network and data clustering.

PURPOSE: To group microcrystalline celluloses (MCCs) using a combination of artificial neural network (ANN) and data clustering. METHODS: Radial basis function (RBF) network was used to model the torque measurements of the various MCCs. Output from the RBF network was used to group the MCCs using a data clustering technique known as discrete incremental clustering (DIC). Rheological or torque profiles of various MCCs at different combinations of mixing time and water:MCC ratios were obtained using mixer torque rheometry (MTR). Correlation analysis was performed on the derived torque parameter Torque(max) and physical properties of the MCCs. RESULTS: Depending on the leniency of the predefined threshold parameters, the 11 MCCs can be assigned into 2 or 3 groups. Grouping results were also able to identify bulk and tapped densities as major factors governing water-MCC interaction. MCCs differed in their water retentive capacities whereby the denser Avicel PH 301 and PH 302 were more sensitive to the added water. CONCLUSIONS: An objective grouping of MCCs can be achieved with a combination of ANN and DIC. This aids in the preliminary assessment of new or unknown MCCs. Key properties that control the performance of MCCs in their interactions with water can be discovered.

Cellulose↗

Prediction of maximum daily ozone level using combined neural network and statistical characteristics.

Analysis and forecasting of air quality parameters are important topics of atmospheric and environmental research today due to the health impact caused by air pollution. As one of major pollutants, ozone, especially ground level ozone, is responsible for various adverse effects on both human being and foliage. Therefore, prediction of ambient ozone levels in certain environment, especially the ground ozone level in densely urban areas, is of great importance to urban air quality and city image. To date, though several ozone prediction models have been established, there is still a need for more accurate models to develop effective warning strategies. The development of such models is difficult because the meteorological variables and the photochemical reactions involved in ozone formation are very complex. The present work aims to develop an improved neural network model, which combines the adaptive radial basis function (ARBF) network with statistical characteristics of ozone in selected specific areas, and is used to predict the daily maximum ozone concentration level. The improved method is trained and testified by hourly time series data collected at three air pollutant-monitoring stations in Hong Kong during 1999 and 2000. The simulation results demonstrate the effectiveness and the reliability of the proposed method.

Air Pollutants↗

Reduced bio-basis function neural networks for protease cleavage site prediction.

This paper presents a new neural learning algorithm for protease cleavage site prediction. The basic idea is to replace the radial basis function used in radial basis function neural networks by a so-called bio-basis function using amino acid similarity matrices. Mutual information is used to select bio-bases and a corresponding selection algorithm is developed. The algorithm has been applied to the prediction of HIV and Hepatitis C virus protease cleavage sites in proteins with success.

Algorithms↗

Hierarchical state space partitioning with a network self-organising map for the recognition of ST-T segment changes.

The problem of maximising the performance of ST-T segment automatic recognition for ischaemia detection is a difficult pattern classification problem. The paper proposes the network self-organising map (NetSOM) model as an enhancement to the Kohonen self-organised map (SOM) model. This model is capable of effectively decomposing complex large-scale pattern classification problems into a number of partitions, each of which is more manageable with a local classification device. The NetSOM attempts to generalize the regularization and ordering potential of the basic SOM from the space of vectors to the space of approximating functions. It becomes a device for the ordering of local experts (i.e. independent neural networks) over its lattice of neurons and for their selection and co-ordination. Each local expert is an independent neural network that is trained and activated under the control of the NetSOM. This method is evaluated with examples from the European ST-T database. The first results obtained after the application of NetSOM to ST-T segment change recognition show a significant improvement in the performance compared with that obtained with monolithic approaches, i.e. with single network types. The basic SOM model has attained an average ischaemic beat sensitivity of 73.6% and an average ischaemic beat predictivity of 68.3%. The work reports and discusses the improvements that have been obtained from the implementation of a NetSOM classification system with both multilayer perceptrons and radial basis function (RBF) networks as local experts for the ST-T segment change problem. Specifically, the NetSOM with multilayer perceptrons (radial basis functions) as local experts has improved the results over the basic SOM to an average ischaemic beat sensitivity of 75.9% (77.7%) and an average ischaemic beat predictivity of 72.5% (74.1%).

Electrocardiography↗

A new EM-based training algorithm for RBF networks.

In this paper, we propose a new Expectation-Maximization (EM) algorithm which speeds up the training of feedforward networks with local activation functions such as the Radial Basis Function (RBF) network. In previously proposed approaches, at each E-step the residual is decomposed equally among the units or proportionally to the weights of the output layer. However, these approaches tend to slow down the training of networks with local activation units. To overcome this drawback in this paper we use a new E-step which applies a soft decomposition of the residual among the units. In particular, the decoupling variables are estimated as the posterior probability of a component given an input-output pattern. This adaptive decomposition takes into account the local nature of the activation function and, by allowing the RBF units to focus on different subregions of the input space, the convergence is improved. The proposed EM training algorithm has been applied to the nonlinear modeling of a MESFET transistor.

Algorithms↗

A Deep Model Framework for Morphological Trait Imputation Across Taxonomic Groups.

Incomplete morphological trait data pose major hurdles for trait-based analyses, particularly when missing values, multicollinearity, and sparse sampling constrain inference. These issues limit our ability to quantify trait variation and explore broad patterns of functional differentiation across taxa. Here, we introduce FS-DeepRBFNet, which overcomes these pitfalls through integrating correlation-based feature selection with a dual-layer adaptive radial basis function (RBF) network. This end-to-end approach effectively reduces noise and captures both linear allometric trends and nonlinear morphological relationships. We tested the framework on a large species-level morphological trait dataset of Chinese birds and further validated its cross-taxon transferability using the Amphibian Database (Caudata). FS-DeepRBFNet consistently outperformed conventional methods such as KNN, Random Forest, and XGBoost, demonstrating superior predictive accuracy across multiple traits. Beyond improvements, the model revealed biologically interpretable trait associations and stable cross-taxon generalization. These results demonstrate that FS-DeepRBFNet provides a robust and biologically grounded solution for morphological trait prediction, enabling reliable imputation for comparative phylogenetics, functional ecology, and biodiversity forecasting in data-limited situations.

cross‐taxon transferability↗

Bio-basis function neural network for prediction of protease cleavage sites in proteins.

The prediction of protease cleavage sites in proteins is critical to effective drug design. One of the important issues in constructing an accurate and efficient predictor is how to present nonnumerical amino acids to a model effectively. As this issue has not yet been paid full attention and is closely related to model efficiency and accuracy, we present a novel neural learning algorithm aimed at improving the prediction accuracy and reducing the time involved in training. The algorithm is developed based on the conventional radial basis function neural networks (RBFNNs) and is referred to as a bio-basis function neural network (BBFNN). The basic principle is to replace the radial basis function used in RBFNNs by a novel bio-basis function. Each bio-basis is a feature dimension in a numerical feature space, to which a nonnumerical sequence space is mapped for analysis. The bio-basis function is designed using an amino acid mutation matrix verified in biology. Thus, the biological content in protein sequences can be maximally utilized for accurate modeling. Mutual information (MI) is used to select the most informative bio-bases and an ensemble method is used to enhance a decision-making process, hence, improving the prediction accuracy further. The algorithm has been successfully verified in two case studies, namely the prediction of Human Immunodeficiency Virus (HIV) protease cleavage sites and trypsin cleavage sites in proteins.

Artificial Intelligence↗

A generalized growing and pruning RBF (GGAP-RBF) neural network for function approximation.

This paper presents a new sequential learning algorithm for radial basis function (RBF) networks referred to as generalized growing and pruning algorithm for RBF (GGAP-RBF). The paper first introduces the concept of significance for the hidden neurons and then uses it in the learning algorithm to realize parsimonious networks. The growing and pruning strategy of GGAP-RBF is based on linking the required learning accuracy with the significance of the nearest or intentionally added new neuron. Significance of a neuron is a measure of the average information content of that neuron. The GGAP-RBF algorithm can be used for any arbitrary sampling density for training samples and is derived from a rigorous statistical point of view. Simulation results for bench mark problems in the function approximation area show that the GGAP-RBF outperforms several other sequential learning algorithms in terms of learning speed, network size and generalization performance regardless of the sampling density function of the training data.

Algorithms↗

On-line learning in RBF neural networks: a stochastic approach.

The on-line learning of Radial Basis Function neural networks (RBFNs) is analyzed. Our approach makes use of a master equation that describes the dynamics of the weight space probability density. An approximate solution of the master equation is obtained in the limit of a small learning rate. In this limit, the on line learning dynamics is analyzed and it is shown that, since fluctuations are small, dynamics can be well described in terms of evolution of the mean. This allows us to analyze the learning process of RBFNs in which the number of hidden nodes K is larger than the typically small number of input nodes N. The work represents a complementary analysis of on-line RBFNs, with respect to the previous works (Phys. Rev. E 56 (1997a) 907; Neur. Comput. 9 (1997) 1601), in which RBFNs with N >> K have been analyzed. The generalization error equation and the equations of motion of the weights are derived for generic RBF architectures, and numerically integrated in specific cases. Analytical results are then confirmed by numerical simulations. Unlike the case of large N > K we find that the dynamics in the case N < K is not affected by the problems of symmetric phases and subsequent symmetry breaking.

Algorithms↗

An efficient MDL-based construction of RBF networks.

We propose a method for optimizing the complexity of Radial basis function (RBF) networks. The method involves two procedures: adaptation (training) and selection. The first procedure adaptively changes the locations and the width of the basis functions and trains the linear weights. The selection procedure performs the elimination of the redundant basis functions using an objective function based on the Minimum Description Length (MDL) principle. By iteratively combining these two procedures we achieve a controlled way of training and modifying RBF networks, which balances accuracy, training time, and complexity of the resulting network. We test the proposed method on function approximation and classification tasks, and compare it with some other recently proposed methods.

Journal Article↗

Assessing rbf networks using DELVE.

In this paper, different methods for training radial basis function (RBF) networks for regression problems are described and illustrated. Then, using data from the DELVE archive, they are empirically compared with each other and with some other well known methods for machine learning. Each of the RBF methods performs well on at least one DELVE task, but none are as consistent as the best of the other non-RBF methods.

Algorithms↗

Simulation studies on neural predictive control of glucose using the subcutaneous route.

A novel strategy for closed-loop control of glucose using subcutaneous (s.c.) tissue glucose measurement and s.c. infusion of monomeric insulin analogues was developed and evaluated in a simulation study. The proposed control strategy is an amalgamation of a neural network and nonlinear model predictive control (NPC) technique. A radial basis function neural network was used for off-line system identification of Nonlinear Auto Regressive model with eXogenous inputs (NARX) model of the glucoregulatory system. The explicit NARX model obtained from the off-line identification procedure was then used to predict the effects of future control actions. Numerical studies were carried out using a comprehensive model of glucose regulation. The system identification procedure enabled construction of a parsimonious network from the stimulated data, and consequently, design of a controller using multiple-step-ahead predictions of the previously identified model. According to the simulation results, stable control is achievable in the presence of large noise levels and for unknown or variable physiological or technical time delays. In conclusion, the simulation results suggest that closed-loop control of glucose will be achievable using s.c. glucose measurement and s.c. insulin administration. However, the control limitations due to the s.c. insulin administration makes additional action of the patient at meal time necessary.

Computer Simulation↗

An efficient sequential learning algorithm for growing and pruning RBF (GAP-RBF) networks.

This paper presents a simple sequential growing and pruning algorithm for radial basis function (RBF) networks. The algorithm referred to as growing and pruning (GAP)-RBF uses the concept of "Significance" of a neuron and links it to the learning accuracy. "Significance" of a neuron is defined as its contribution to the network output averaged over all the input data received so far. Using a piecewise-linear approximation for the Gaussian function, a simple and efficient way of computing this significance has been derived for uniformly distributed input data. In the GAP-RBF algorithm, the growing and pruning are based on the significance of the "nearest" neuron. In this paper, the performance of the GAP-RBF learning algorithm is compared with other well-known sequential learning algorithms like RAN, RANEKF, and MRAN on an artificial problem with uniform input distribution and three real-world nonuniform, higher dimensional benchmark problems. The results indicate that the GAP-RBF algorithm can provide comparable generalization performance with a considerably reduced network size and training time.

Algorithms↗

Predicting spatial data with RBF networks.

Spatial prediction needs to account for spatial information, which makes conventional radial basis function (RBF) networks inappropriate, for they assume independent and identical distribution. In this paper, we fuse spatial information at different layers of RBF. Experiments show fusion at hidden layer gives the best result and suggest that the optimal value is around one for the coefficient, which is used in the linear combination at the output layer.

Algorithms↗

On the structure and initial parameter identification of Gaussian RBF networks.

We consider the efficient initialization of structure and parameters of generalized Gaussian radial basis function (RBF) networks using fuzzy decision trees generated by fuzzy ID3 like induction algorithms. The initialization scheme is based on the proposed functional equivalence property of fuzzy decision trees and generalized Gaussian RBF networks. The resulting RBF network is compact, easy to induce, comprehensible, and has acceptable classification accuracy with stochastic gradient descent learning algorithm.

Algorithms↗