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[Differences in nutrition behavior between weekends and work days: results of the nutrition survey in 1984/85 of the MONICA project in Augsburg].

Seven-day food records of the MONICA project Augsburg dietary survey 1984/85 in 899 men aged 45-64 years were used to compare food and nutrient intake of weekdays and weekends. Differences were found in food intake. The mean intake of energy, macronutrients and especially alcohol was higher on weekends, whereas the dietary constituents independent of total energy intake, as percentage supply of energy from macronutrients, did not show huge differences.

Alcohol Drinking↗

Understanding chronic malnutrition in childhood and old age: role of energy balance research.

Undernutrition is commonly associated with chronic disease in children and the elderly. Overnutrition is also, but less commonly, associated with chronic illness. In most diseases malnutrition arises because energy intake does not match energy output. Traditionally, the focus of research has been on abnormalities in energy expenditure, in the belief that these factors were the main determinants of energy imbalance. Recent studies using the doubly-labelled-water method to measure total energy expenditure, combined with more complex study design, have suggested an alternative conclusion. In many chronic diseases patient behaviour, and particularly energy intake, is responsible for energy imbalance and malnutrition. Energy balance studies have therefore provided a useful foundation for the design of strategies aimed at preventing or managing chronic malnutrition. However, modifying patient behaviour is an ambitious undertaking which may not be within the scope of existing clinical nutrition services. A number of non-traditional models of managing chronic malnutrition in children and the elderly are promising. Increasing recognition of the value of systematic review will also provide improved strategies for prevention and management of chronic malnutrition.

Aged↗

[Osteoporosis and intake of carbohydrates].

Adequate energy intake including carbohydrates is essential to maintain bone mass. Emaciation along with deficiency in nutrients, such as calcium, vitamin D, and protein is a significant risk factor for bone loss, and should be avoided. However, there is no clinical evidence that shows the direct effects of carbohydrate on bone mass. On the other hand, excessive intake of carbohydrates results in obesity, which causes other metabolic diseases such as diabetes mellitus (DM). Therefore, dietary regimen must be balanced in general, and complications and conditions of individual patients should be taken well into account. In addition, energy intake is a basis for adequate exercise in order to maintain physical activity and ideal body weight, which will further decrease the risk of bone fracture. Some indigestible carbohydrates, such as inulin and oligofructose, are shown to increase the availability of minerals from foods, and thus can be beneficial to bone mass.

Body Weight↗

Effects of exercise intensity on food intake and appetite in women.

BACKGROUND: Increasing exercise intensity has been shown to reduce energy intake in men. OBJECTIVE: The main objective of this study was to investigate the effects of exercise intensity on energy intake in women. DESIGN: Thirteen moderately active (peak oxygen uptake: 44.0 +/- 4.7 mL . kg(-1) . min(-1)) women [body mass index (in kg/m(2)): 22.2 +/- 2.4; age: 22.2 +/- 2.0 y] were subjected to 3 experimental conditions: control with no exercise and 2 equicaloric (350 kcal) low- (LIE) and high- (HIE) intensity exercise sessions at 40% and 70% of peak oxygen uptake, respectively. After each session, the participants ate ad libitum from buffet-type meals at lunch and dinner and ate snacks during the afternoon and evening. Visual analogue scales were used to rate appetite. RESULTS: More energy was ingested at lunchtime after the HIE session than after the control session (878 +/- 309 and 751 +/- 230 kcal, respectively; P = 0.02). Relative energy intake (postexercise energy intake corrected for the energy cost of exercise above the resting level) at lunch was lower after the LIE session than after the control session (530 +/- 233 and 751 +/- 230 kcal, respectively; P < 0.001) and was lower after the HIE session than after the control session (565 +/- 301 and 751 +/- 230 kcal, respectively; P < 0.01). Similarly, daily energy intake tended to increase during the HIE session relative to that during the control session. No treatment effect was found for appetite scores throughout the experiment. CONCLUSION: The results suggest that HIE increases energy intake in women.

Adult↗

Acute feline leukemia virus infection causes altered energy balance and growth inhibition in weanling cats.

Naturally occurring retroviral infections cause progressive weight loss, immune suppression, invasion by opportunistic organisms, and eventual death. Feline leukemia virus (FeLV) inhibited growth and decreased energy intake in seven experimentally infected weanling cats compared with age- and sex-matched controls. Remarkably, changes in energy intake, energy expenditure, and weight gain occurred in the acute phase of infection prior to the systemic/productive bone marrow phase of FeLV infection. In other words, growth inhibition developed before FeLV infection was clinically detectable with use of standard enzyme-linked immunosorbent assay or fixed-cell immunofluorescence assays of circulating neutrophils and platelets. Acutely infected, previremic cats consumed 25% less energy [Day 4 postinoculation to Day 16 postinoculation (p < 0.05)] and expended 20% less energy [Day 8 postinoculation to Day 18 postinoculation (p < 0.05)] compared with control cats. Growth stunting of inoculated cats began by Day 11 postinoculation (p < 0.05) and was not corrected during the remaining 4 months of the study. Thus, experimental FeLV infection causes perturbations of metabolism and energy balance resulting in permanent growth impairment. Secondly, detrimental metabolic effects begin in the acute phase of retroviral infection, prior to the clinically detectable phase of FeLV infection.

Acute Disease↗

High- or low-salt diet from weaning to adulthood: effect on body weight, food intake and energy balance in rats.

OBJECTIVE: To get some additional insight on the mechanisms of the effect of salt intake on body weight. DESIGN AND METHODS: Rats were fed a low (LSD), normal (NSD), or high (HSD) salt diet. In a first set, body weight, tail-cuff blood pressure, fasting plasma thyroid-stimulating hormone, triiodothyronine, L-thyroxine, glucose, insulin, and angiotensin II were measured. Angiotensin II content was determined in white and brown adipose tissues. Uncoupling protein 1 expression was measured in brown adipose tissue. In a second set, body weight, food intake, energy balance, and plasma leptin were determined. In a third set of rats, motor activity and body weight were evaluated. RESULTS: Blood pressure increased on HSD. Body weight was similar among groups at weaning, but during adulthood it was lower on HSD and higher on LSD. Food intake, L-thyroxine concentration, uncoupling protein 1 expression and energy expenditure were higher in HSD rats, while non-fasting leptin concentration was lower in these groups compared to NSD and LSD animals. Plasma thyroid-stimulating hormone decreased on both HSD and LSD while plasma glucose and insulin were elevated only on LSD. A decrease in plasma angiotensin II was observed in HSD rats. On LSD, an increase in brown adipose tissue angiotensin II content was associated to decreased uncoupling protein 1 expression and energy expenditure. In this group, a low angiotensin II content in white adipose tissue was also found. Motor activity was not influenced by the dietary salt content. CONCLUSIONS: Chronic alteration in salt intake is associated with changes in body weight, food intake, hormonal profile, and energy expenditure and tissue angiotensin II content.

Adipose Tissue, Brown↗

Nutritional intakes in community-dwelling older Japanese adults: high intakes of energy and protein based on high consumption of fish, vegetables and fruits provide sufficient micronutrients.

The purpose of this study was to obtain detailed data on the dietary intake of energy, macronutrients, and micronutrients, especially minerals and vitamins, of healthy free-living people over the age of 70 in Japan and to clarify the correlations among nutrient intakes. The survey was conducted in November 2001 for 57 persons (men: 31, women: 26) aged 74 y (born in 1927) living in Niigata City, Japan. A precise weighing method was used to record food intake for three consecutive days. Nutrient intake was calculated based on the Standard Tables of Food Composition in Japan (5th ed.). The intakes of energy and total protein were 44.8+/-7.7 kcal/kg/d and 1.80+/-0.35 g/kg/d for men and 38.1+/-7.6 kcal/ kg/d and 1.51+/-0.26 g/kg/d for women. These values are significantly higher than those proposed by the current Recommended Dietary Allowances (RDAs) and the data by the 2001 National Nutrition Survey in Japan. The energy intake ratios from protein, carbohydrate and fat for men were 16 : 58 : 22, respectively, and the residual part was alcohol. For women, the ratios were 16 : 62 : 22. The proportion of total protein intake that consisted of animal protein was 57.8% for men and 52.8% for women. For both sexes, all of the mean daily intakes of nine minerals and 12 vitamins were higher than those prescribed for elderly Japanese people (> or =70 y) in the RDAs. Significant strong correlations were found between total protein intake and intakes of vitamins D, B2 and B6, as well as niacin and pantothenic acid (p<0.0001). Among the nine minerals, the correlations were very strong between potassium and magnesium, calcium and phosphorus, magnesium and iron, magnesium and copper, iron and copper, and zinc and copper (r's>0.700). For vitamins, strong correlations were found between vitamin A and folic acid, vitamin B2 and pantothenic acid, and folic acid and pantothenic acid. Furthermore, strong relationships were observed between potassium and folic acid, potassium and pantothenic acid, potassium and dietary fiber, phosphorus and vitamin B2, phosphorus and pantothenic acid, iron and folic acid, zinc and vitamin B12, and copper and vitamin B12. From these results, it is evident that age is not an important determinant of dietary intake among apparently healthy elderly Japanese people aged 74 y. In addition, the high intake of energy and protein in the Japanese dietary pattern, based upon high consumption of fish and/or shellfish, vegetables, and fruits, provide sufficient minerals and vitamins.

Aged↗

The effect of increasing physical activity on voluntary food intake and energy balance.

Energy homeostasis with increased physical activity is dependent upon compensatory changes in intake. Results from metabolic balance studies in obese women indicate a dissociation of energy intake from that expended as exercise. Voluntary intake remained fixed at a sedentary level whether activity was added to or subtracted from total daily expenditure. The importance of physiological factors such as excess energy stores or psychological factors such as habit or sensory perceptions in obesity needs consideration.

Adult↗

Effects of diet forage-to-concentrate ratio and intake on energy metabolism in growing beef heifers: whole body energy and nitrogen balance and visceral heat production.

Effects of diet forage-to-concentrate ratio and intake on balances of energy and nitrogen and portal-drained viscera (PDV), liver and kidney blood flow and O2 consumption were measured in seven growing beef heifers. Isonitrogenous pelleted diets containing approximately 75% alfalfa or 75% concentrate were fed daily as 12 equal meals every 2 h at two isoenergetic metabolizable energy intakes. A split-plot design was used, with 4 wk for adaptation to diet followed by 3-wk intake periods within 6-wk diet periods. Heifers consumed and digested less dry matter, energy and nitrogen when fed the 75% concentrate vs. 75% alfalfa diet at equal metabolizable energy. Heifers fed the 75% concentrate diet produced less heat energy and retained more tissue energy than when fed the 75% alfalfa diet. Blood flow for PDV, liver and kidneys increased with intake and was greater when heifers were fed the 75% alfalfa vs. 75% concentrate diet. Increased PDV and liver O2 uptake accounted for 44 and 72% of heat increment for the 75% concentrate and 75% alfalfa diets, respectively. Greater PDV uptake of O2 accounted for 72% of the decrease in tissue energy of heifers fed the 75% alfalfa vs. 75% concentrate diet at equal metabolizable energy.

Animal Feed↗

Energy intake-independent modulation of triglyceride metabolism by glucocorticoids in the rat.

This study aimed to dissociate the peripheral effects of adrenalectomy (ADX) on triglyceride (TG) metabolism from those it exerts centrally on energy intake and to determine the impact of diet composition therein. Rats were fed either rodent chow or a diet high in sucrose and fat (HSF) and were adrenalectomized or left intact and pair fed to the ADX animals. Liver TG content, an index of hepatic TG production, was not affected by ADX, but was increased twofold by the HSF diet. ADX decreased the rate of hepatic TG secretion by 41% in chow-fed but not in HSF-fed animals. Triglyceridemia and postheparin plasma lipase activities remained largely unchanged by treatments. ADX decreased insulinemia fivefold in chow-fed rats, but less so in HSF-fed animals. Likewise, subcutaneous and visceral adipose depots were 40-60% smaller in ADX than in intact pair-fed rats given chow, but the effect of ADX was dampened by consumption of the HSF diet. Although smaller, adipose tissues of ADX rats maintained a higher activity of lipoprotein lipase (LPL) than those of intact pair-fed rats, whereas muscle LPL was decreased. The study confirms that in the presence of reduced energy intake, corticosterone contributes to the maintenance of adipose stores and that the consequences of its absence tend to be attenuated when a high-energy diet is fed. The study further shows that, contrary to ad libitum feeding conditions, most determinants of TG metabolism, such as hepatic TG stores, triglyceridemia, postheparin plasma LPL, and adipose tissue LPL, are minimally affected by glucocorticoids when consumption of a high-energy diet is restricted, suggesting that glucocorticoids affect TG metabolism mostly indirectly through their central action on ingestive behavior.

Adipose Tissue↗

High energy flux mediates the tonically augmented beta-adrenergic support of resting metabolic rate in habitually exercising older adults.

The sympathetic nervous system contributes to resting metabolic rate (RMR) via beta-adrenergic receptor (beta-AR) stimulation of energy metabolism. RMR and beta-AR support of RMR are greater in habitually exercising compared with sedentary older adults possibly due to greater energy flux (magnitude of energy intake and energy expenditure during energy balance). In 10 older adults regularly performing aerobic endurance exercise (mean +/- se, 66 +/- 1 yr) compared with baseline, a reduction in energy flux (via abstention of exercise and proportional reduction in dietary intake) decreased (P < 0.05) energy expenditure (7746 +/- 440 vs. 9630 +/- 662 kJ.d(-1)), caloric intake (7808 +/- 431 vs. 9433 +/- 528 kJ.d(-1)), RMR (5192 +/- 167 vs. 5401 +/- 209 kJ.d(-1)), and skeletal muscle sympathetic nervous system activity (36 +/- 2 vs. 42 +/- 2 bursts.min(-1)). Significant beta-AR support of RMR was observed at baseline (167 +/- 42 kJ.d(-1)) but not during reduced energy flux. The change in RMR from baseline to reduced energy flux was related to the corresponding change in beta-AR support of RMR (r = 0.77, P = 0.009). No changes were observed in seven time controls (69 +/- 3 yr) who maintained energy flux. High energy flux is a key mechanism contributing to the elevated RMR and beta-AR support of RMR in habitually exercising older adults. Maintenance of high energy flux via regular exercise may be an effective strategy for maintaining energy expenditure and preventing age-associated obesity.

Aged↗

A new simplified dietary history method for measuring intake of energy and macronutrients.

In this dietary history method, which preserves the characteristic features of the full dietary history, the principle of simplification is to group several food items into common codes. This enables us to complete both an interview and all nutrient calculations within 35-45 min. In this study we investigated whether the method could replace a 4-day food record for assessing individual intakes of energy and macronutrients. Dietary data were collected from 75 individuals (57 males and 18 females). Protein intake was validated by comparison with 24 h urinary nitrogen excretion (33 subjects), and energy intake was compared to weight maintenance energy intake from a later controlled diet study (19 subjects). When average intakes according to the two methods were compared, dietary history intakes were slightly higher than food record results (0-13%) except for alcohol. Comparison with urinary nitrogen excretion and energy intake data indicate that this is due to an overestimation by the dietary history method, rather than an underestimation by the food record. For individuals most of the correlations between the two methods were in the range 0.5-0.7, but alcohol correlation was down to 0.2. About 75% (53-93%) of the individuals at the extremes of the intake distribution were classified similarly by both methods. Although the ability of the dietary history to predict the individual food record results was unreliable the two methods agreed better when classifying individuals relative to certain cut-off points (sensitivity and specificity values of 0.7-0.9, relative to the food records).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

A randomized intervention since infancy to reduce intake of saturated fat: calorie (energy) and nutrient intakes up to the age of 10 years in the Special Turku Coronary Risk Factor Intervention Project.

OBJECTIVE: To evaluate the longitudinal impact of dietary counseling on children's nutrient intake. DESIGN: A prospective, randomized, clinical trial. PARTICIPANTS: Children were recruited to the study between December 1, 1989, and May 30, 1992. At the age of 7 months, children were randomized to the intervention group (n = 540) or the control group (n = 522) and were followed up until the age of 10 years. Intervention Families in the intervention group have, since randomization, received regularly individualized counseling about how to modify the quality and quantity of fat in the child's diet, the goal being an unsaturated-saturated fat ratio of 2:1. MAIN OUTCOME MEASURES: Nutrient intakes between the ages of 4 and 10 years based on annual 4-day food records. RESULTS: The fat intake of the intervention children was constantly around 30% of the calorie (energy) intake, while that of the control children was 2 to 3 calorie percentage units higher (P<.001). The intervention children received 2 to 3 calorie percentage units less saturated fats and 0.5 to 1.0 calorie percentage unit more polyunsaturated fats than the control children (P<.001 for both). However, neither group reached the 2:1 goal set for the unsaturated-saturated fatty acid ratio. The vitamin and mineral intakes of the intervention and control children closely resembled each other despite the marked differences in fat intake. CONCLUSION: Individualized, biannually given, fat intake-focused dietary counseling that began at the child's age of 8 months continued to influence favorably the diet of 4- to 10-year-old intervention children without disadvantageous dietary effects, but the 2:1 goal for unsaturated-saturated fat ratio was not reached.

Age Factors↗

The impact of high- or low-fat cafeteria foods on nutrient intake and growth of rats consuming a diet containing 30% energy as fat.

The objective of this study was to determine the impact of high-fat and low-fat cafeteria foods on energy intake and body composition of growing rats. Two sets of 30 male Sprague-Dawley rats weighing either 90 g or 280 g, were each divided into two groups of eight and two groups of seven animals, matched for average weight. All animals were offered a semi-purified diet containing 30% kJ fat. After ten days, initial body composition, carcass energy and serum lipids, insulin and glucose were determined in seven rats from each age group. Seven rats in each age group continued to receive the semi-purified diet ad libitum, eight received semi-purified diet plus one high-fat cafeteria food each day and eight received semi-purified diet plus one low-fat cafeteria food each day. After 38 days, body composition, efficiency of energy retention and serum lipids, insulin and glucose were determined. Food and energy intakes were greater for rats offered cafeteria foods compared with controls. Those given low-fat foods ate the greatest quantity of food but those fed high-fat foods had the highest energy intake. High-fat foods increased fat intake to approximately 43% of energy. Low-fat foods decreased fat intake to approximately 24% kJ. There was no effect of treatment on weight gain or lean body mass of either age group. Young rats fed low-fat cafeteria foods had less body fat than their controls. There was no significant increase in body fat content of rats fed high-fat cafeteria foods.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

Diet, prevalence and 10-year mortality from coronary heart disease in 871 middle-aged men. The Zutphen Study.

The Zutphen Study is a longitudinal investigation among middle-aged men of relationships between diet, other risk characteristics, and coronary heart disease (CHD). In 1960, dietary data were collected by the cross-check dietary history method. CHD mortality data were collected during 10 years of follow-up. The 14 men with CHD at baseline consumed 524 kcal/day less than the 857 CHD-free men. During 10 years of follow-up, 30 men who were initially free of CHD died from CHD. Those men consumed 273 kcal/day less than men who did not die from CHD. The inverse relationship between energy intake and CHD became stronger when energy intake was expressed per kg of body weight. Dietary cholesterol per 1000 kcal was significantly positively related to CHD, while vegetable protein, polysaccharides, and dietary fiber were significantly inversely related to CHD. These relationships were no longer statistically significant when energy intake per kg of body weight was added to the logistic model. The inverse relationship between energy intake per kg of body weight and CHD became insignificant when subscapular skinfold and serum cholesterol were added to the logistic model. It is concluded that the influence of energy intake per kg of body weight on CHD is mediated through other risk characteristics: subscapular skinfold and serum cholesterol.

Adult↗

[Comparison of the effect of linolenic acid and eicosapentaenoic acid on prostaglandin biosynthesis and thrombocyte function in humans].

Platelet aggregation, bleeding time, prostaglandin biosynthesis and plasma cholesterol fatty acids were investigated in 12 healthy females (25-32 years), who were given different amounts of linolenic acid (0%, 4%, 8%, 12%, 16% of total energy intake) or eicosapentaenoic acid (1.7%) with formula diets for 2 weeks each. Linolenic and eicosapentaenoic acids prolonged the bleeding time and inhibited platelet aggregation and prostaglandin biosynthesis. These effects became apparent after a linolenic acid intake of 12% of the energy intake. A decrease in PGE in 24 h urine was observed after intake of linolenic acid amounting to 8% of energy intake. Eicosapentaenoic acid influenced all parameters measured ten times more than linolenic acid. Linolenic acid intake had no effect on the ratio of linoleic/arachidonic acids in plasma cholesterol esters in contrast to in vitro findings. Thus energy intake comprising 1.7% of eicosapentaenoic acid is sufficient to affect thrombocyte function in man. The concomitant intake of linolenic-type fatty acids inhibits the biosynthesis of prostaglandins E2 and F2 alpha to different degrees.

Adult↗

Longitudinal changes in the intake of energy and macronutrients of elderly Europeans. SENECA Investigators.

OBJECTIVE: To assess longitudinal changes in intakes of energy and macronutrients in elderly Europeans. DESIGN: Longitudinal study including a dietary assessment in 1988/1989, which was repeated in 1993. SETTING: Serial data were collected in nine European towns: Belgium: Hamme (H/B); Denmark: Roskilde (R/DK); France: Haguenau (H/F) and Romans (R/F); Italy: Padua (P/I); the Netherlands: Culemborg (C/NL); Portugal: Vila Franca de Xira (V/P); Spain: Betanzos (B/E) and Switzerland: Yverdon (Y/CH). In other centres dietary intake data were collected in 1993 only: Portugal: Coimbra (C/P); Poland: Marki (M/PL); Northern Ireland: Ballymoney-Limavady-Portstewart (BLP/NI/UK) and United States: Mansfield (Connecticut) (M/CT/USA). SUBJECTS AND METHODS: Using standardized methodologies, data were collected from a random stratified sample of elderly men and women born between 1913 and 1918. In 1993 dietary intake data were collected from 1125 subjects by a modified validated dietary history method. RESULTS: Over the 4-year study period, a decline in mean energy intake of one MJ or less per day was observed in most towns, which was significant (P < 0.01) in only four of the towns. The within- and between-centre variation of change was large. Overall, a slight decline was reported for all macronutrients and with the exception of protein, large within and between centre variations were observed in both men and women. CONCLUSION: Intake of energy and macronutrients was found to decline with age. This may be of special concern for small eaters.

Aged↗