[Intestinal tuberculosis].
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A review of the clinical records of all patients with the diagnosis of abdominal tuberculosis, admitted to the Ethio-Swedish Children's Hospital (ESCH), Addis Ababa, Ethiopia, over a ten year period was made. There were 57 patients that fulfilled the inclusion criteria, accounting for 0.22% of all admissions. Both sexes were nearly equally affected. In more than a quarter of the patients (30%), the diagnosis of tuberculosis was not considered at admission. Fever, weight loss, night sweating and abdominal pain were common presenting symptoms. The role of positive Mantoux and elevated erythrocyte sedimentation rate (ESR) as an aid to diagnosis were limited. The number of admitted patients with abdominal tuberculosis at ESCH is much lower than what has been reported from other African countries. The findings of the present study clearly indicate the need for a high index of clinical suspicion. Laparoscopic and peritoneal biopsy should be included in the diagnostic work up of patients suspected of having abdominal tuberculosis.
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An 80-year-old Caucasian male presented with a seven-week history of diarrhoea and weight loss. Distal duodenal biopsies showed partial villous atrophy but he failed to respond to a gluten-free diet. Subsequently he developed a right iliac fossa mass associated with radiological evidence of ileocaecal ulceration. Colonoscopic biopsies from the caecum showed non-caseating granulomata and Ziehl-Neelsen (ZN) staining and culture for acid-fast bacilli (AFB) were negative. Crohn's disease was diagnosed and he was started on steroids. Although he showed an initial response, his condition then deteriorated and he died after six weeks. ZN staining of tissue at postmortem showed AFBs. Although a rare diagnosis in the UK, a high index of suspicion should be maintained for ileocaecal TB in patients with appropriate clinical features, even if classical risk factors for TB are absent.
We describe a patient with HIV-1 infection and disseminated tuberculosis complicated with intestinal localization. The authors describe the clinical and radiological findings and the histological and microbiological diagnosis corroboration of the intestinal biopsy. The incidence of tuberculosis has been increasing during the last decade. The resurgence of tuberculosis, secondary to AIDS pandemic, mandates that the clinician be aware of the wide spectrum of presentation of intestinal tuberculosis.
We report a patient with isolated involvement of common bile duct by tuberculosis. The diagnosis was established by histological examination of the resected specimen. Surgery and antitubercular chemotherapy resulted in complete recovery.
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We report a 44 years old male, presenting with an eight months history of right lower quadrant pain, diarrhea and weight loss. Colonoscopy showed a proliferative and ulcerated lesion in the cecum, with necrotic areas. Barium enema showed an extensive irregular stenosis with rigidity of cecum and ascending colon. The endoscopic biopsy showed numerous granulomas with giant multinucleated cells of Langhans type. A right colectomy was performed with a good postoperative evolution. Anti tuberculosis treatment was started two weeks later and was well tolerated. The patient is currently asymptomatic after two years of followup.
We report a rare association of carcinoma and tuberculosis of the stomach. It is difficult to explain the simultaneous occurrence or a causal relationship of the two diseases.
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UNLABELLED: This work aimed to assess the significance of abnormal gastroduodenal uptake in the 67Ga scintigraphy of HIV patients who have been studied for fever of unknown origin. The examinations of 12 patients who had had a normal panedoscopy when the 67Ga scan was done, were selected. One out of 7 patients without gastroduodenal 67Ga uptake was diagnosed of non-specific gastritis. Five patients had abnormal gastroduodenal involvement in the 67Ga scan. One of them was diagnosed of high grade lymphoma. The other 4 patients were diagnosed of mycobacteriosis. CONCLUSIONS: Although controversy exists in the literature, the current study shows a high correlation between abnormal gastroduodenal uptake in the 67GA scan of HIV (+) patients and the presence of gastroduodenal disease.
Intestinal tuberculosis (ITB) is an always difficult clinical diagnosis; we must keep in mind it in the diagnosis of patients with abdominal pain, even without concomitant lung involvement. Seven patients with ITB were revised. Five patients were male and two female, with a mean age of 45 years; all of them presented abdominal pain. Ileocecal region was involved in 71.4% of the cases. Only one patient showed old specific pulmonary lesions radiologically. Neoplasia was the most frequent clinical presumption. ITB diagnosis was made only in one case, as first possibility. Histopathological examination revealed caseous granulomas in all the cases, with acid-alcohol resistant bacilli in 71.4% of them. We want to underline the need of thinking about ITB, in the clinical evaluation of in specific abdominal pain, above all in immunosuppressed patients, and to emphasize the importance of histopathologic findings in the final diagnosis of this entity.