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[Averaging results of site recognition can increase the accuracy of annotating the human genome].

A systemic approach is proposed, which makes it possible to increase the accuracy of recognition of functional sites in arbitrary DNA sequences. The approach is based on the Central limit theorem and consists in the averaging of a large number of recognitions of a particular site. To obtain a rather large number of recognitions within the framework of conventional methods of recognition, consensus, and frequency matrix, 20 novel oligonucleotide alphabets were used. The approach was used to study the binding sites of GATA-1 and C/EBP transcription factors. It was found that the averaged recognition of these sites is more precise than each of specific recognitions, which just follows from the Central limit theorem.

Base Sequence↗
PubMed2000

Genetic resources: an annotated bibliography of internet and other resources.

The Internet has caused a major boom in the field of genetics. Internet use among the public and health care professionals continues to rise, but caution must be exercised when searching for information. This article presents some guidelines for determining good web sites, then follows with a compilation of Internet and other relevant genetics resources.

Genetic Diseases, Inborn↗
PubMed2001

An annotated history of craniofacial surgery and intentional cranial deformation.

The history of craniofacial surgery and the use of intentional cranial deformation is a long and varied one. Researching some of the earliest medical writings and reviews of early terracotta and stone figures from throughout the world clearly revealed that these two forms of treatment were widely extant. Intentional cranial deformation was used for a number of reasons including beautification, tribal identification, and social stature. The development of craniofacial surgery is a more modern practice and its historical evolution is reviewed in the context of techniques and the personalities involved.

Adult↗
PubMed2001

Annotation: conceptions of intelligence.

This paper argues for the scientific utility of the concept "intelligence". In the first section three common arguments against the validity of general intelligence are discussed and dismissed. The second section presents the evidence in favour of the proposition that individual differences in IQ may be based on differences in speed of information processing. However, the third section shows that executive functions, particularly inhibitory processes, represent a more likely basis for the development of intelligence. The theory of the minimal cognitive architecture underlying intelligence and development (Anderson, 1992a) shows how speed and executive functioning might represent two dimensions to g--one an individual differences (within age) dimension based on speed and the other a developmental dimension based on changing executive functioning. In the fourth section this theory is used to generate new insights on the nature of intellectual disability and specific cognitive deficits and to make practical suggestions for educational intervention for low-IQ children.

Cognition↗
PubMed2001

Aquatic therapy in pediatrics: annotated bibliography.

"Aquatic therapy" refers to therapeutic intervention taking place in water. The purpose of this review is to summarize the published articles in the rehabilitation literature from 1979 through 1999 that relate to the use of aquatic therapy as an intervention for children and adolescents with neuromuscular and musculoskeletal diagnoses. Despite the trend toward evidence-based practice, a paucity of literature exists related to aquatic therapy for children. Most of the available articles are case reports and other descriptions of clinical practice. The research reports are limited in design and scope, and subjects had a wide variety of ages and diagnoses.

Exercise Therapy↗