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[New color-photographic observation of thermoluminescence of sliced rock samples].

New observation technique has been established for the thermoluminescence photography using extremely high-sensitive color films. Considering future application to the geological fields, a granite was selected as a testing material. The sliced specimens (0.5- 0.7 mm in thickness), which were irradiated with a 60Co source, were mounted on the heater attached with a thermocouple, which was connected to a microcomputer for measuring the temperature. The samples were heated in the temperature range of 80-400 degrees C by operating the camera-shutter controlled with the microcomputer. Four commercially available films (Kodak-1000(ASA), -400, Sakura-400, Fuji-400) could give apparently detectable color-images of artificial thermoluminescence above a total absorbed dose of 880 Gy(88 krad). The specimens, irradiated upto 8.4 kGy(840 krad), allowed easily to distinguish the distinct appearance of the thermoluminescence images depending on kinds of white mineral constituents. Moreover, such color images were changeable with the heating temperature. Sakura-400 film has proved the most colorful images from aspects of color tone although Kodak-1000 film showed the highest sensitivity. By applying this Kodak-1000, it was found that the characteristic color image due to natural thermoluminescence was significantly observed on the Precambrian granite which was exposed with natural radiation alone since its formation. This simple and interesting technique, obtainable surface information reflecting impurities and local crystal defects in addition to small mineral constituents, was named as the thermoluminescence color imaging (abbreviated to TLCI) technique by the authors and its versatile applications were discussed.

Color↗

[Endoscopy by color television--a new technique? (author's transl)].

The routine endoscopic examination by color television is possible be new technical developments. For routine color television - endoscopy an efficient three-tube-camera should be used, directly attached to the endoscope. For demonstration purposes or to control technical proceedings in the field of operative endoscopy the one-tube-color television camera can be sufficient, even if there are difficulties also for the experienced examiner to read findings from the television screen. This difficulty do not exist with the three-tube-camera. The resolution power of the endoscope in comparison to the television picture of the endoscopic color television picture is not different. The resolution power is limited by the endoscopes. An enlargement of the endoscopic picture by changing the focus of the objective gives no improvement. We have excellent experiences with the routine color television-endoscopy during colonoscopy. With a three-tube-camera the total examination can be controlled while the one-tube-camera is only valid to insert the coloscope. The color television endoscopy enables to produce a large archive of endoscopic findings for teaching purposes without secondary cost and with a description during the active examination. Our experiences with routine endoscopy with color television proves that this technique is an improvement.

Colonoscopes↗

[Color Doppler echography in the tissue characterization of renal masses].

To investigate color-Doppler US capabilities in tissue characterization, 42 renal masses were studied from November, 1993, to July, 1994. B-mode morphologic patterns were studied first and then integrated with color flow patterns; color areas and blood flow distribution were assessed for each lesion. Color signals were used as a guide to obtain arterial and venous Doppler spectra and to calculate flow velocities and pulsatility index (PI). Based on the us morphologic appearance, the 42 lesions were divided into 3 groups: A) lesions with morphologic and volumetric patterns of malignancy; B) small lesions (< 3 cm, > 3 cm < 5 cm); C) complex cysts. Data were organized and analyzed statistically; some findings were found to be typical of malignancy: hypervascularity, intralesional arterial signals with high flow velocities (systolic peak cut-off: 0.3-0.4 m/sec), high PI values (> 1) and, finally, color signals inside complex cysts. Our results suggest that color-Doppler US is a useful tool to assess renal masses vascularity, with the color-Doppler technique increasing US diagnostic accuracy. Nevertheless, small lesions need more careful study because their features are poorly demonstrated even with CT and MRI.

Adenocarcinoma↗

Noninvasive assessment of renal artery stenosis. A comparison of MR angiography, color Doppler sonography, and intraarterial angiography.

The purpose of this study was to evaluate MR angiography (MRA) and color Doppler sonography as noninvasive screening methods in suspected renovascular hypertension. Fifty-five consecutive patients with arterial hypertension were examined prospectively using high resolution 3-D TOF MRA and color Doppler sonography. Intraarterial angiography was the standard of reference. Stenoses of 60% or more were regarded as significant. MR angiograms were evaluated by 3 independent observers who studied 110 main renal arteries. All 8 significant stenoses and 2 occlusions were correctly classified with MRA while one 60% stenosis was underestimated by color Doppler sonography. Mild stenoses were overestimated by MRA in 4 and by color Doppler sonography in 6 cases. A drawback of both methods was the large number of not evaluable arteries (6 in MRA, 11 in color Doppler sonography). These arteries were regarded as pathologic because stenosis could not be excluded. Due to this fact specificities of MRA and color Doppler sonography were 90% and 85% respectively. Accessory vessels were detected in 47% (8/17) by MRA and in 0% (0/17) by color Doppler sonography.

Adult↗

Neural correlates of attentive selection for color or luminance in extrastriate area V4.

Rhesus monkeys were trained on a conditional orientation discrimination task in order to assess whether attentive selection for a color or luminance stimulus feature would affect visual processing in extrastriate area V4. The task required monkeys to select a bar stimulus based on its color or luminance and then to discriminate the angular tilt of the selected stimulus. The majority of neurons (74%) were selectively activated when the color or luminance of the stimulus in the receptive field matched the color or luminance of the cue. The activity was attenuated when there was not a match between the stimulus and the cue. The differential activation was based on the presence or absence of the stimulus feature and was independent of spatial location. Across the population of V4 neurons, optimal stimuli that matched the selected color or luminance elicited about twice the activity as stimuli that did not match the selected feature. The feature-selective changes in activity were observed to develop beginning about 200 msec after the stimulus onset and were maintained over the remainder of the behavioral trial. In this task the activity of V4 neurons reflected a selection based on the cued feature and not simply the physical color or luminance of the receptive field stimulus. Under these conditions, the topographic representation of the neural activity in area V4 highlights the potential targets in the visual scene at the expense of background objects. These observations offer a physiological counterpart to psychophysical studies suggesting that stimuli can be preferentially selected in parallel across the visual field on the basis of a unique color or luminance feature.

Analysis of Variance↗

Quantitating nuclear opacification in color Scheimpflug photographs.

PURPOSE: To test the validity of the color component subtraction method, a new objective technique of measuring nuclear cataract, and to correlate the tangent values of the different degrees of nuclear opacities to their corresponding subjective nuclear cataract grading using the Lens Opacities Classification System II and to another objective method of measuring nuclear cataract. METHODS: Densitometries for red, green, and blue colors of the color Scheimpflug image were conducted simultaneously along the anteroposterior axis of the lens nucleus. The three color curves were subtracted from each other, giving rise to three subtracted curves: blue-red, green-blue, and red-green. This technique was applied to 99 color Scheimpflug photographs taken in 99 eyes of 51 patients with varying degrees of nuclear opacities. Using linear regression analysis, the regression coefficient obtained, called tangent value (TV), represents the degree of nuclear opacification. RESULTS: Higher tangent value indicated greater nuclear opacification and was associated with higher correlation coefficient. This was seen graphically as an increased steepness in the slope of the subtracted curve. Good correlation existed between the subjective nuclear opacity grading and the objective tangent value. When the tangent values were correlated to the mean density of the three original color curves, good correlation was present in red and green, but only fair for blue, where maximum light scattering occurs. CONCLUSIONS: These results support the validity of color component subtraction technique in measuring nuclear cataract. This technique provides quantitative measures of nuclear opacification, has good reproducibility, and is useful for monitoring nuclear cataract longitudinally.

Cataract↗

Specifying the relation between novel and known: input affects the acquisition of novel color terms.

4 studies investigate how differential input affects preschoolers' abilities to learn novel color words. 3-, 4-, and 5-year-old children saw objects in novel shapes and colors and heard a novel color label for the object. Labels were presented through ostensive definition (e.g., "See, it's mauve"), corrective linguistic contrast (e.g., "See, it's not purple; it's mauve"), or an inclusion statement (e.g., "See, it's mauve; it's a kind of purple"). 4- and 5-year-old children interpreted the novel word as a shape term when ostensive information was provided but as a color term when additional information, either contrastive or inclusive, specified a relation between the novel term and a known label for that color. Furthermore, children who consistently interpreted the novel word as a color word tended to treat the novel and known labels as mutually exclusive color terms if they heard contrastive information, whereas they tended to treat the words as hierarchically related if they heard inclusion information. 3-year-olds generally did not make use of either type of information in determining the semantic domain of the novel word or the relation between terms.

Child↗

The application of a standard color coding system to paint in forensic science.

The procedure described for the measurement of paint colors represents an attempt to standardize the measurement of color in the forensic science service and provides a means of communicating colors between individuals. The effect of sample size on color comparisons has been discussed. It has been shown that color data collected from many control samples of paint flakes can provide the frequency of occurrence of paint colors. The errors involved in color comparisons have been assessed and the system has been shown to be a practicable one.

Color↗

Color change and fracture resistance of two preveneered stainless-steel crowns after sterilization.

PURPOSE: This study compared the fracture resistance and color stability of two commercially available, preveneered stainless-steel crowns before and after four sterilization techniques. METHODS: Thirty-five crowns from each of two manufacturers were divided into five groups. Four groups were sterilized twice using one of the following techniques: steam autoclave at both 121 degrees C (15 PSI) for 20 min and 132 degrees C (30 PSI) for 8 min; Chemiclave with formaldehyde at 132 degrees C for 20 min; and 2% gluteraldehyde for 10 h. The fifth group from each manufacturer was the control. Color of facings was measured before and after each sterilization in triplicate using a colorimeter, and the variance of each color parameter was analyzed for significance. Fracture resistance was measured for each group and differences between the control and experimental groups analyzed for significance. RESULTS: The results of this study show that high heat and chemical sterilizations have little effect on color and fracture resistance of the preveneered stainless-steel crowns. Student's t test analysis revealed a significantly decreased resistance to fracture with Kinder Krowns sterilized in 2% gluteraldehyde. Chemiclave sterilization caused the most negative color change in all three color parameters measured for both types of crowns. CONCLUSIONS: As neither steam technique produced significant changes in fracture resistance or color changes that were clinically detectable, the results of this study indicate that the two steam techniques tested can be used by clinicians to sterilize either Kinder Krowns or Nu Smile preveneered stainless-steel crowns.

Color↗

[The specific nature of the color and brightness components of the human visual evoked potential].

In order to gain an insight into the electrophysiological cortical mechanisms of color discrimination and to compare the results with psychophysiological data summarized in the previous publications as the spherical model of color discrimination a problem was specified to identify color and brightness components of human evoked potentials. The experiments were carried out with alternating pairs of light flashes constituted of five colors (white and four main colors; red, blue, yellow, and green). Each of the light stimuli varied by seven brightness levels. Color and brightness components (N87 and P120, respectively) were reasonably reliably detected in all cases of substitution of stimuli with identical or different spectra. However, the latency and amplitude analysis of N87 and P120 components in these cases showed that N87 reflects not only color but also brightness information. It makes it possible to draw on the analogy between the N87 as one of the earliest components and N1 in primate cortical evoked potential and suggest that these components reflect the activity of cells receiving information directly from the lateral geniculate body. This process can be considered as the first stage of cortical analysis of chromatic and achromatic light characteristics. The brightness component P120, probably, represents the activity of cortical cells related to the analysis of nonchromatic stimuli characteristics, such as form, movement, orientation, etc. These characteristics are also based on luminance gradients and contrasts, however, in contrast to N87, these characteristics are not directly related with brightness of light.

Analog-Digital Conversion↗

Quantitative assessment of color vision impairment in workers exposed to toluene.

Color vision was examined by the Lanthony-D-15 desaturated test in two groups of workers occupationally exposed to toluene and in a control group. Biological parameters of toluene exposure were analyzed: toluene in air and in venous blood, orthocresol, and hippuric acid in urine after workshift. The first exposed group, Group E1, comprised 41 workers (toluene exposure ranged from 11.30 to 49.30 ppm), and the second exposed group, Group E2, comprised 32 workers (toluene exposure ranged from 66.00 to 250.00 ppm). The nonexposed group, Group NE, comprised 83 subjects. Each group was divided into two subgroups; alcohol consumers and nonconsumers. Color vision loss was expressed as a color confusion index (CCI) and as age and alcohol intake-adjusted color confusion index (AACCI). Significantly higher values of CCI and AACCI (both P < 0.0001) in Group E2 in comparison to Group NE, and significantly higher CCI (P < 0.0001) and AACCI (P < 0.05) values in Group E2 in comparison to Group E1 were established. The significant difference in CCI value between alcohol consumers and nonconsumers was established only in Group NE (P < 0.05). In Group NE significant correlation was found between CCI value as a dependent and age and alcohol intake as independent cofactors (R2 = 0.45; P = 0.0000). In Group E2 significant correlation was established between CCI as a dependent factor and age, toluene in air, and alcohol intake (R2 = 0.72; P = 0.0001), or between CCI as dependent and age, toluene in blood and alcohol intake as independent cofactors (R2 = 0.68; P = 0.0002). In Group E1 significant correlation was established only between CCI and age (P <0.005). In Group E2, AACCI value significantly correlated with toluene in air (P < 0.0001), toluene in blood (r < 0.0005), orthocresol (P < 0.005) and hippuric acid (P < 0.005) in urine after workshift. There were no differences between smokers and nonsmokers in CCI values in the examined groups. Results of this study indicate that toluene in exposed workers can impair color vision. The role of alcohol intake and age influence on color vision loss cannot be ignored in such workers.

Adult↗

Reversible color vision loss in occupational exposure to metallic mercury.

Color vision was evaluated in twenty-one mercury exposed workers and referents matched for sex, age, tobacco smoking, and alcohol habits. The Lanthony 15 Hue desaturated panel (D-15 d) was applied. In the workers, mean urinary Hg (HgU) was 115+/-61.5 microg/g creatinine; in all but one the values exceeded the biological limit (BEI) proposed by the American Conference of Governmental Industrial Hygienists. A dose-related subclinical color vision impairment was observed in Hg-exposed workers compared to the referents. Just after the survey, working conditions were improved. Twelve months later the workers were reexamined. Mean HgU was 10.0 microg/g creatinine and in no subjects was the BEI exceeded. Color perception was significantly improved compared to the first examination and, furthermore, no differences were observed between exposed workers and referents. The results add evidence that the color vision loss observed during the first part of the study was related to Hg exposure and, moreover, show that this effect is reversible. These data indicate that metallic Hg can induce a reversible impairment in color perception. This suggests that color vision testing should be included in studies on the early effects of Hg. The possibility of applying the D-15 d as an early effect index in the biological monitoring of Hg exposed workers should also be entertained.

Adult↗

Prevalence of congenital color deficiencies in secondary-school students in Tehran.

PURPOSE: A population-based study was conducted to determine the prevalence of color deficiencies in secondary-school students (ages 12-14) in Tehran. METHODS: A total of 2,058 students (1,136 males, 922 females) were examined with Ishihara pseudoisochromatic color plates. RESULTS: In the study population, 97 cases of defective color vision were detected, including 93 males and 4 females. The affected individuals all had negative histories of previous systemic and ocular disease or chronic use of medications. The visual acuity was 20/20 and the fundus was normal in all affected students. Of the 93 cases of defective color vision in males (8.18%), 56 cases (4.93%) involved deuteranomaly, 13 (1.14%) protanomaly, 13 (1.14%) deuteranopia, and 11 (0.97%) protanopia. The four cases in females (0.43%) involved deuteranomaly in three cases (0.32%) and protanomaly in 1 case (0.11%). Deuteranopia and protanopia were not detected in females. CONCLUSION: This is the first study to determine the prevalence of congenital color blindness in Iran. The results agree with reports of prevalence of congenital color blindness from Western Europe.

Adolescent↗

Experience in early infancy is indispensable for color perception.

Early visual experience is indispensable to shape the maturation of cortical circuits during development. Monocular deprivation in infancy, for instance, leads to an irreversible reduction of visually driven activity in the visual cortex through the deprived eye and a loss of binocular depth perception. It was tested whether or not early experience is also necessary for color perception. Infant monkeys were reared for nearly a year in a separate room where the illumination came from only monochromatic lights. After extensive training, they were able to perform color matching. But, their judgment of color similarity was quite different from that of normal animals. Furthermore, they had severe deficits in color constancy; their color vision was very much wavelength dominated, so they could not compensate for the changes in wavelength composition. These results indicate that early visual experience is also indispensable for normal color perception.

Animals↗

Color vision in epilepsy patients treated with vigabatrin or carbamazepine monotherapy.

PURPOSE: To investigate color vision in epilepsy patients treated with vigabatrin or carbamazepine monotherapy and to evaluate the association between vigabatrin-induced visual field defects and dyschromatopsia. DESIGN: Nonrandomized comparative trial. PARTICIPANTS: Thirty-two epilepsy patients treated with vigabatrin monotherapy, 18 patients treated with carbamazepine monotherapy, and 47 age-matched healthy controls were examined. MAIN OUTCOME MEASURES: Color vision was examined with Standard Pseudoisochromatic Plates 2 (SPP2) screening test, Farnsworth-Munsell 100 (FM 100) hue test, and Color Vision Meter 712 anomaloscope. RESULTS: Abnormal color perception was found in 32% of the epilepsy patients treated with vigabatrin monotherapy and 28% of the epilepsy patients treated with carbamazepine monotherapy. The total error score in the Farnsworth-Munsell 100 hue test was abnormally high in the vigabatrin monotherapy patients who had concentrically constricted visual fields and a statistically significant correlation was found between the temporal visual field extents and the age-adjusted Farnsworth-Munsell 100 total error score in vigabatrin monotherapy patients (R = .533, P = 0.003 in the right eye, R = .563, P = 0.001 in the left eye). Four of 31 (12%) vigabatrin monotherapy patients, and 1 of 18 (6%) carbamazepine monotherapy patients had a blue axis in Farnsworth-Munsell 100 hue test. In the anomaloscope, there were a few pathologic findings in both groups. In the SPP2 screening test, a few plates were not seen in both groups. CONCLUSIONS: Both examined antiepileptic drugs, vigabatrin and carbamazepine, cause acquired color vision defects. The abnormal color perception seems to be associated with constricted visual fields in the vigabatrin monotherapy patients. The duration of carbamazepine therapy correlates with high FM100 total error score. The best method for detecting dyschromatopsia in patients treated with vigabatrin or carbamazepine was the Farnsworth-Munsell 100 hue test. The SPP2 screening test does not seem to be useful in clinical practice.

Adult↗

Quantification of color vision with cone contrast sensitivity.

Human color vision is based fundamentally on three separate cone photopigments. Hereditary color deficiency, which affects up to 10% of males, results from an absorption shift or lack of L or M cone phototoreceptors. While hereditary S cone deficiency is rare, decreased S cone sensitivity occurs early in eye disease, underscoring the importance of quantifying S cone function. Our purpose is to describe a novel approach for quantifying human color vision based on the photopigments of normal color vision. Colored letters, visible to a single cone type, are presented in graded steps of cone contrast to determine the threshold for letter recognition. This approach quantifies normal color vision, indicates type and severity of hereditary deficiency, and reveals sensitivity decrements in various diseases.

Color Perception↗

Computerized color-vision test based upon postreceptoral channel sensitivities.

An automated, computerized color-vision test was designed to diagnose congenital red-green color-vision defects. The observer viewed a yellow appearing CRT screen. The principle was to measure increment thresholds for three different chromaticities, the background yellow, a red, and a green chromaticity. Spatial and temporal parameters were chosen to favor parvocellular pathway mediation of thresholds. Thresholds for the three test stimuli were estimated by four-alternative forced-choice (4AFC), randomly interleaved staircases. Four 1.5-deg, 4.2 cd/m2 square pedestals were arranged as a 2 x 2 matrix around the center of the display with 15-minute separations. A trial incremented all four squares by 1.0 cd/m2 for 133 ms. One randomly chosen square included an extra increment of a test chromaticity. The observer identified the different appearing square using the cursor. Administration time was approximately 5 minutes. Normal trichromats showed clear Sloan notch as defined by log (deltaY/deltaR), whereas red-green color defectives generally showed little or no Sloan notch, indicating that their thresholds were mediated by their luminance system, not by the chromatic system. Data from 107 normal trichromats showed a mean Sloan notch of 0.654 (SD = 0.123). Among 16 color-vision defectives tested (2 protanopes, 1 protanomal, 6 deuteranopes, & 7 deuteranomals), the Sloan notch was between -0.062 and 0.353 for deutans and was < -0.10 for protans. A sufficient number of color-defective observers have not yet been tested to determine whether the test can reliably discriminate between protans and deutans. Nevertheless, the current data show that the test can work as a quick diagnostic procedure (functional trichromatism or dichromatism) of red-green color-vision defect.

Automation↗

Use of the Mollon-Reffin minimalist color vision test with young children.

PURPOSE: We evaluated the Mollon-Reffin Minimalist (M-R M) color vision test to determine how successfully young children can perform the task and to compare success rates with the American Optical Hardy Rand Rittler (HRR) test and a preferential-looking type test based on the F2 plates (the Pease-Allen color test [PACT]). METHODS: Participants included 146 children (aged 3-10 years) and 32 older subjects (aged 11-39 years). The M-R M test uses 3 series of colored caps coinciding with protan, deutan, and tritan confusion axes, with 6 saturations along each axis. The observer must identify a single colored cap from gray caps of varying lightness. The PACT test consists of 2 cards with targets for detecting red-green and blue-yellow color deficiencies. The tester judges the location of the target on the basis of the child's looking and/or pointing responses. The HRR was performed according to standard instructions, although a more flexible scoring protocol was also used. RESULTS: A significant difference in the children's performance between the "test" item of the 3 tasks emerged (Cochran Q test, P<.001): all children successfully completed the M-R M, 90% successfully completed the PACT, and 88% successfully completed the HRR. Few errors were made on the M-R M red-green series, even among children aged 3 to 4 years, although errors were made with the least saturated blue-yellow cap at all ages. Recommendations are made for the use of the M-R M with children. CONCLUSIONS: The M-R M test can be performed by young children and may prove to be especially useful for detecting and monitoring acquired color vision defects.

Adolescent↗