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[Problems in pars plana vitrectomy in complicated diabetic retinopathy].

Introduction summarizes basal indications for pars plana vitrectomy (PPV) in complicated diabetic retinopathy (DR) and indications for urgently performed PPV are accentuated. Further there are explained various peculiarities of PPV in DR, various components forming the solution for infusion, advantages of the cerclage, some problems with surgery of the complicated cataracts, contribution and indications of the use of the silicone oil for the inner tamponade. Special attention was paid to the postoperative complications affecting the cornea, rubeosis iridis, iatrogenic tears of the retina and recurring intravitreal hemorrhages. Thereafter author concludes this review evaluating prognosis and long-term results of PPV and DR. He emphasizes the technical difficulties of this operation and recommends to concentrate the performance of this operation into the centres specialized for vitreoretinal surgery.

Diabetic Retinopathy↗

[Is the prognosis of pars plana vitrectomy in diabetic retinopathy dependent on the general status of the diabetic?].

Results of pars plana vitrectomy (PPV) were compared in two groups of patients. The first group was formed from 105 eyes of 87 diabetics without clinical signs of the diabetic nephropathy or nephropathy without decrease of renal functions. The other group was formed from 64 eyes of 50 diabetics suffering from diabetic nephropathy in the stage of the renal insufficiency. In the first group PPV was successful during the mean observatory period of 26 months, in 59 from 105 eyes (56%) and the mean visual acuity was 0.12. In the second group PPV was successful, during the mean observatory period of 18 months, in 34 from 64 eyes (53%) and the mean visual acuity was 0.09. Number of the successfully treated PPV was steadily decreasing according to the prolonged period of the further observations, in both mentioned groups: from 85 (81%) after 3 months on 62 (41%) after the interval of 3 years. The mean visual acuity in both followed groups was, with respect to the length of observation, moderately increased. Diabetic nephropathy in the stage of the renal insufficiency was without negative effect on the prognosis of PPV in complicated diabetic retinopathy. The more advanced organ complications of diabetes were not evaluated as contraindications of PPV and the operation may significantly improve the quality of the life of an otherwise heavily ill diabetic patient.

Adult↗

Intraocular human thrombin infusion in diabetic vitrectomies.

The effectiveness of intravitreal thrombin infusion during vitrectomy was prospectively evaluated in eight diabetic patients with persistent vitreous hemorrhages and severe proliferative vitreoretinopathy. A concentration of 80 units/ml of human thrombin diluted in BSS-plus infusion fluid was used. Bleeding time ranged between 2 and 15 seconds (mean, 5 seconds). The reduction of bleeding facilitated surgery. In five of the eight cases the vitreous was clear one day postoperatively. One month postoperatively six eyes had clear media. No additional postoperative intraocular inflammation developed. These results suggest that human thrombin causes less inflammation than bovine thrombin.

Diabetic Retinopathy↗

[Fluorescent angiographic and rheographic evaluation of the ocular hemodynamics in patients with proliferative diabetic retinopathy after closed vitrectomy].

Rheo-ophthalmography has been employed in examinations of the hemodynamics in 42 patients with proliferative diabetic retinopathy, aged 21 to 78; in 16 of these patients with sufficiently transparent media the fundus oculi has been examined by fluorescent angiography. The examinations have revealed an impaired hemodynamic balance, manifesting by a low rheographic coefficient (1.55 +/- 0.12%) and a considerably longer time of the venous circulation (18.8 +/- 0.5 s). Vitrectomy not only removes neovascularization, proliferates, and changed vitreous, but also normalizes the hemodynamic parameters at the expense of shortening the venous system and removing the venous congestion.

Adult↗

[Results of vitrectomy for diabetic traction retinal detachment involving the macula; a comparison of six-month and three-year postoperative findings].

Three-year follow-up examinations were performed on 45 cases that underwent pars plana vitrectomies for diabetic retinopathy complications from 1982 to 1983. All of these cases had traction retinal detachment involving the macula. Visual improvement was noted in 27 eyes (60%) and 11 eyes (24%) had worse visual acuity at 6 months after surgery. Final visual improvement was noted in 21 eyes (47%) at the there-year follow-up examinations. Five (11%) of the 45 cases had better visual acuity at the three-year examination than at six months, 18 (40%) had the same visual acuity, but 22 (49%) had poorer vision at the three-year examination. Out of those cases, 28 eyes (62%) had totally attached retina 6 months after operation and the results in those eyes were quite stable at three years. Of these, 19 (68%) had the same or better visual acuity at three years compared with six months. But if retinal detachment was present at 6 months, the prognosis was very poor at the three-year examination with a visual acuity of less than hand motions. Reattachment of the retina is most important to maintain good prognosis for surgical treatment for diabetic retinopathy with traction retinal detachment.

Adult↗

[Effectiveness of the treatment of early hemophthalmos and its sequelae by closed vitrectomy].

The author analyzes the results of surgical treatment of traumatic hemophthalmia and the relationship of these results with the time of the hemorrhage in 54 patients (54 eyes). Twenty-five patients have been operated on within 2 months after wounding (Group 1), the rest 29 later (Group 2). All the patients presented with incurable changes in the vitreous body, therefore drug therapy could not be effective. The surgery has resulted in vision improvement in 8 of Group 1 patients and in 24 of Group 2 patients; 17 patients of these 24 have been discharged from hospital with a visual acuity of 0.1 or higher. These results evidence that the best terms of optic vitrectomy are 2-6 months after the perforating wound.

Adolescent↗

Trabeculectomy, ECCE with PC-IOL implant, and vitrectomy after malignant glaucoma.

A patient with narrow-angle glaucoma developed a post peripheral iridectomy malignant glaucoma in both eyes. The intraocular pressure (IOP) in both eyes was controlled with mydriatics, cycloplegics, and Diamox for 2 years. Subsequently the patient developed a dense cataract and uncontrollable IOP in her left eye. An extracapsular cataract extraction, posterior chamber lens implant, and trabeculectomy were combined with an anterior vitrectomy. The IOP in both eyes has been controlled for 3 years postoperatively.

Aged↗

Vitrectomy for nondiabetic vitreous hemorrhage. Not associated with vascular disease.

Forty-nine consecutive eyes with nonclearing vitreous hemorrhage not associated with retinal or choroidal vascular disease underwent vitrectomy. Etiologies included vitreous hemorrhage during anterior segment surgery (22 eyes), blunt trauma (8 eyes), retinal tears with and without retinal detachment (8 eyes), Terson's syndrome (2 eyes), avulsed retinal vessel (1 eye), and idiopathic cases (8 eyes). The final visual acuity improved in 48 eyes (98%). Follow-up was 6-91 months (mean, 20 months). Of the 49 eyes, 40 eyes (82%) had a best postoperative visual acuity of 20/100 or better, 31 eyes (63%) had visual acuity of 20/40 or better, and 12 eyes (24%) had visual acuity of 20/20. The major complications included intraoperative iatrogenic retinal breaks (5 eyes), postoperative progressive cataract (7 eyes), late retinal detachment (4 eyes) and recurrent vitreous hemorrhage (2 eyes). The major complication associated with later visual loss was progressive cataract.

Adolescent↗

Conjunctival pigmentation following pars plana vitrectomy.

A 32-year-old white man developed distinctive episcleral and conjunctival pigmentation surrounding a sclerotomy site 6 weeks after vitrectomy and retinal reattachment surgery. The conjunctival lesion was biopsied during a second operation to remove an epiretinal membrane causing macular pucker. Light and electron microscopic studies demonstrated melanin granules extracellularly and within macrophages.

Adult↗

Effects of intravitreal injection of fluorosilicone oil after vitrectomy in the rabbit eye.

Because fluorosilicone oil is heavier than silicone oil, it may be superior in the therapy of proliferative vitreoretinopathy. To evaluate the ocular toxicity of fluorosilicone oil we performed pars plana lentectomy and vitrectomy on 14 rabbit eyes and injected approximately 1.5 mL of the oil (viscosity 10,000 centistoke) into the vitreous chamber of 10. No clinical or histologic evidence of toxic ocular effects was noted up to 2 months after the procedure.

Animals↗

Treating the complications of diabetic retinopathy with pars plana vitrectomy.

The results of 150 cases of pars plana vitrectomy performed at the Clínica Barraquer, Bogotá, Colombia were studied as a treatment of diabetic retinopathy. Factors considered in this study were age, indication for surgery, type of surgery, insulin dependence, risk of complication, and postoperative treatment.

Adult↗

Pars plana vitrectomy and intravitreal silicone oil injection in eyes with rubeosis iridis.

We postoperatively evaluated the data from 10 patients who underwent pars plana vitrectomy and intravitreal silicone oil injection for complications of proliferative diabetic retinopathy and rubeosis, or for proliferative vitreoretinopathy and rubeosis. There was no change in the zone of iris affected by the rubeosis or in the calibre of rubeotic vessels. Visual acuity improved in two patients and stayed the same in eight. Retinas were completely attached in 50% and partially attached in 30% of the patients on the last follow-up visit. The use of silicone oil in these patients caused no untoward effects in these severely diseased eyes.

Adult↗

Anaesthetic management of vitrectomy.

The problems and anaesthetic management of patients undergoing vitrectomy are discussed in a series of 111 patients who underwent 129 operations.

Adolescent↗

Pars plana vitrectomy for the complications of diabetic retinopathy: a report on 131 cases.

The results of primary vitrectomy for the complications of proliferative diabetic retinopathy were explored in 131 eyes of 105 patients. A minimum of 6 months' follow-up was obtained. The primary indications for surgery were persistent vitreous hemorrhage (in 66% of the eyes) and progressive tractional macular detachment (in 31%). Technical (surgical) success (clearing of the ocular media or relief of macular traction, or both) was achieved by the time of the last examination in 69% of the eyes; it was achieved in 70% of those with persistent vitreous hemorrhage and in 68% of those with tractional macular detachment. Visual improvement was observed in 55% of all the eyes.

Adolescent↗

[Retinal detachment: temporary internal tamponade with silicone oil after vitrectomy. Anatomic and functional results].

Forty-seven patients with retinal detachment treated by vitrectomy and silicone oil injection benefited from semi-premature ablation of the oil: after a mean of 5 months for supple retinal detachments and 6 1/2 months for those associated with vitreoretinal proliferation. Ablation was performed after obtaining a solid chorioretinal scar by cryopexy or endodiathermy, usually combined with laser panphotocoagulation. The technique used for ablation is described. After follow up for from 9 months to 3 1/2 years (mean 18 months) two-thirds of the patients had flat retinas. Recurrences developed usually during the first month. An explanation for these relapses is proposed.

Adolescent↗

Pars plana lensectomy and vitrectomy by ultrasonic fragmentation: Part III--Results in eyes without other ocular pathology or an implant.

The records of 320 eyes without other ocular pathology undergoing pars plana lensectomy and vitrectomy by ultrasonic fragmentation for routine cataract extraction without an implant were reviewed retrospectively. Three hundred two (302/320-94.4%) had vision between 20/20-20/40. Reasons for vision less than 20/40 in 18/320 (5.6%) eyes included 5/320 (1.5%) with retinal detachments, 11/320 (3.4%) with clinically apparent cystoid maculopathy, 1/320 (0.3%) with a macular hole, and 1/320 (0.3%) with retained lens material. Comparison was made between 184 lensectomies performed by the original technique and 136 pars plana lensectomies performed by the modified technique. Vision between 20/20-20/40 was achieved by 168/184 (91.3%) of the original technique group versus 134/136 (98.5%) of the modified technique group. In the latter group, there was one retinal detachment (0.7%), one macular hole (0.7%) and no clinical cystoid maculopathy. Fluorescein angiography performed three months postoperatively in eyes having vision of 20/20-20/40 of the modified lensectomy group showed cystoid maculopathy in one eye which had undergone trauma-induced wound dehiscence.

Aged↗