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Periodic alternating nystagmus clearing after vitrectomy.

Periodic alternating nystagmus 1) may be related to vestibulocerebellar system disease, 2) may occur with loss of vision, and 3) may be congenital in origin. We report the case of a patient with acquired periodic alternating nystagmus in whom the nystagmus followed bilateral vitreous hemorrhages. Upbeating nystagmus was interposed between the right beating and left beating phases. Bilateral vitrectomy resulted in the prompt disappearance of the nystagmus. The importance of visual function in relation to periodic alternating nystagmus and associated motility disturbances is emphasized.

Aged↗

Toxicity of antineoplastic drug combinations in vitrectomy infusion fluid.

We evaluated a combination of various antineoplastic drugs used in vitrectomy infusion fluid for toxicity. A combination of 250 micrograms/ml of 5-fluorouracil with each of the following agents, 8.0 micrograms/ml of thiotepa or 40 micrograms/ml of etoposide, or 0.1 micrograms/ml doxorubicin, or 0.1 microgram/ml vincristine was tolerated well in the rabbit eyes.

Animals↗

Combined vitrectomy, intraocular microsurgery and liquid silicone in the treatment of proliferative vitreoretinopathy.

This study investigates the effectiveness of combining vitrectomy, scleral buckling, intraocular microsurgery and liquid silicone injection for the treatment of retinal detachment complicated by proliferative vitreoretinopathy: 48 eyes were treated using these techniques combined. Complete attachment was achieved in 16 eyes (33%), partial attachment in 20 eyes (42%), and 12 eyes (25%) remained detached. Vision was improved in 17 eyes (35%), unchanged in 17 eyes (35%), and worse in 14 eyes (30%). Complications included emulsification of the silicone, glaucoma, cataract, band degeneration of the cornea, reproliferation of membranes and passage of silicone into the subretinal space. Significant preservation of mobility vision was achieved. A larger series of patients with longer follow-up will ultimately determine the place of this technique in the management of this complicated problem.

Combined Modality Therapy↗

Diabetic vitrectomy.

Diabetic vitrectomy is usually performed to remove vitreous blood or to relieve traction of the macula. In addition to removing vitreous opacities and severing all anteroposterior connections of the posterior hyaloid face with a cutting and sucking probe, tangential traction in and around the macula is eliminated by sectioning preretinal membranes with intraocular scissors. Complications are significant in terms of both their incidence and their consequences. They include choroidal or subretinal infusion, peripheral and posterior retinal breaks, intraoperative bleeding, and neovascular glaucoma. Proper management can minimize the occurrence and adverse effects of these complications. If prognostic factors are favorable, visual improvement occurs in 78 to 59% of eyes postoperatively. Preoperative iris neovascularization, florid proliferative diabetic retinopathy, long-standing detachment of the macula, and iatrogenic retinal breaks are all correlated with significantly lower success rates. Three independent studies have shown that if visual improvement is present 6 months postoperatively, the results are usually long-standing [2, 8, 20].

Cataract↗

[Obliteration of the posterior holes and tears of the retina by endodiathermy after vitrectomy].

The authors report 19 cases of posterior retinal and tears treated by endodiathermy after vitrectomy. Nine cases were iatrogenic with a retinal break occurring during an intravitreal procedure. The remaining 10 cases were non-iatrogenic. A flat or reapplied retina is a prerequisite for achieving an adequate chorioretinal adhesion by endodiathermy. Short-term internal tamponade by intravitreal gas is recommended in cases with tears and no detachment, whereas, longer term tamponade with intravitreal silicone is preferable when the retina is detached. This method can be used when external retinopexy becomes impractical for lesions too far posterior, or when endophotocoagulation cannot be performed.

Adolescent↗

Vitrectomy and photocoagulation in the management of serous detachment associated with optic nerve pits.

Two cases of serous detachment of the retina associated with congenital pits of the optic nerve were successfully treated with photocoagulation, vitrectomy and gas tamponade. The rationale of management and the results are discussed. It is suggested that this treatment deserves further study to see if early intervention will favourably affect the return of macular function, particularly in cases of optic nerve pits where the serous detachment is of short duration and fixed structural changes at the macula have not occurred.

Adolescent↗

Pars plana vitrectomy for vitreous hemorrhage and retinal vein occlusion.

We studied 16 cases of retinal vein occlusion and vitreous hemorrhage treated by pars plana vitrectomy. The visual acuity in all nine eyes suffering from branch vein occlusion was improved postoperatively, reaching an acuity of 6/6 to 6/12 in 33% of the patients. In the seven eyes suffering from central vein occlusion, however, the postoperative visual acuity results were poor. The incidence of postoperative complications was higher also in the central vein occlusion group.

Eye Diseases↗

Endophthalmitis and pars plana vitrectomy.

A review of all cases of suspected endophthalmitis following cataract extraction seen at one referral hospital between 1979 and 1983 was conducted. Of the 13 cases, 7 were proven by culture to be bacterial endophthalmitis when organisms were grown from aspirates of the aqueous, the vitreous or both. Antibiotic therapy was administered by intravitreal, periocular, topical and systemic routes. In some cases vitrectomy was performed immediately after the diagnostic aspiration or within 24 hours. Poor visual outcome was associated with a long interval between onset of symptoms and admission to hospital, expulsive hemorrhage, retinal detachment or resistance of the microorganism to the intraocularly administered antibiotic. The two eyes that yielded gentamicin-resistant Streptococcus viridans and ended up with no light perception demonstrate the need for simultaneous intravitreal injection of two antibiotics.

Aged↗

Incarceration of asteroid bodies in sclerotomy wound following pars plana vitrectomy.

A 78-year-old man had markedly decreased vision thought to be caused by severe bilateral asteroid hyalosis. Pars plana vitrectomy was performed on one eye, but the patient died shortly after surgery. At autopsy, the sclerotomy site was gaping with vitreous containing asteroid bodies in the wound and surrounding the closing suture. We speculate that wound gaping with vitreous incarceration may be more common than previously suspected.

Aged↗

Penetrating keratoplasty following the use of a temporary keratoprosthesis during pars plana vitrectomy.

The Landers-Foulks temporary keratoprosthesis provides an excellent way to perform pars plana vitrectomy and retinal detachment repair in eyes with opaque corneas. For the most part, these eyes have previously been inoperable. The procedure described in this paper permits this device to be used in conjunction with larger, more routine sized penetrating keratoplasties.

Anterior Chamber↗

Pars plana vitrectomy for subfoveal macular hemorrhage and choroidal neovascular membranes.

1. Choroidal neovascular membranes (CNVM), the abnormal ingrowth of blood vessels from the choroid through Bruch's membrane, remain a major cause of treatable visual loss. 2. Laser photocoagulation is effective in destroying CNVM and preserving central vision in many affected patients. However, laser treatment of subfoveal CNVM irreversibly destroys foveal vision. 3. The utility of vitrectomy techniques for removal of subfoveal macular hemorrhage on CNVM remains unknown pending the results of a randomized, controlled prospective study. 4. Laser photocoagulation remains the treatment of choice for extra- and juxtafoveal CNVM caused by age-related macular degeneration (ARMD), ocular histoplasmosis and idiopathic causes, and for selected subfoveal CNVM caused by ARMD.

Choroid Diseases↗

[Compiling the data of vitrectomy patients. Waiting list organization and quality assurance].

Owing to an increasing frequency of ophthalmological operations and the necessity of shortening the patient's stay in hospital surgical scheduling and data compilation in ophthalmology can only be managed by means of electronic data processing. We present a computer program that compiles a waiting list for vitrectomies and organizes the scheduling of operations. On each patient's first visit a standardized form containing the essential clinical findings if filled out. On the basis of these data the computer, using a specially designed algorithm places the patient in an appropriate position on the waiting list and eventually informs him or her of the date of the operation. In a similar manner the postoperative findings and the results of the follow-up examinations are documented. The system allows effective scheduling based on the urgency of the operation and the prognosis of the disease. Furthermore, it facilitates prospective recording of the clinical course and the treatment outcome. The use of electronic data processing does not only mean an improvement in clinical organization and, especially, in surgical planning, but also facilitates a quick evaluation of clinical studies with a large number of patients.

Algorithms↗

[Pars plana vitrectomy in Terson's syndrome].

Pars plana vitrectomy (PPV) was the operation of choice in haemorrhage (Terson's syndrome) in 7 eyes of 5 patients aged 32 to 47 years. The interval between intracranial haemorrhage and PPV varied from 2 to 10 months. Patients after PPV were followed up for 12 to 84 months. The postoperative course was complicated by successfully operated retinal detachment in two eyes where PPV was not safeguarded by cerclage. The final visual acuity 0.7-1.0 was achieved in 6 of 7 eyes (87%); visual acuity of 0.1 in one eye was due to a lamellar defect of the macula. PPV is the treatment of choice in Terson's syndrome with bilateral haemorrhage into the vitreous body and in massive unilateral extravasation with inadequate spontaneous resorption. Cerclage in PPV in TS is according to the authors essential prevention of iatrogenic retinal detachment.

Adult↗

[Surgical results of vitrectomy for idiopathic macular hole--factors affecting postoperative visual prognosis].

Pars plana vitrectomy was performed on 19 eyes with idiopathic full-thickness macular holes (6 eyes at stage 2, 8 eyes at stage 3, and 5 eyes at stage 4). Factors affecting postoperative visual prognosis were evaluated. Preoperatively a potential acuity meter (PAM) and laser interferometry were used to predict postoperative visual acuity. Resolution of the surrounding fluid cuff and flattening of the macular holes were obtained in 9 eyes (47%). Eight eyes (42%) gained an improvement in visual acuity of 2 lines or more. Most eyes with anatomical success showed functional improvement. Eyes with short duration of macular holes were considered to have better visual postoperative prognosis. The stage of macular holes, however, had no relationship with postoperative visual acuity. Preoperative measurement with laser interferometry was relatively well correlated with postoperative visual acuity (r = 0.54, p = 0.07), but the results of PAM and preoperative visual acuity had poor correlation.

Aged↗

[Vitrectomy combined with posterior chamber intraocular lens implantation in complicated ocular injuries].

Posterior chamber intraocular lens implantation combined with lensectomy-vitrectomy and/or removal of intraocular foreign bodies in one operation was performed on 12 patients with ocular injuries involving both anterior and posterior segments. There were 6 cases with intravitreal or intraretinal foreign bodies, 3 cases with lens dislocation in the vitreous by blunt trauma and 3 cases with vitreous hemorrhage and cataract. Pre-operatively, the visual acuities of all patients ranged from light perception to 0.02, while postoperatively, their visual acuities were 0.5-1.5 in 8 cases, 0.3 in 2 cases, finger counting and 0.05 in other 2 cases which were related to optic nerve atrophy and retinal vein occlusion, respectively. The results suggest that the combined surgery benefit the fast visual rehabilitation in selected young patients with unilateral ocular injuries.

Adult↗