[Follow-up of colorectal polyps--is it really beneficial?].
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Faeces of 1600 outpatients were tested for occult blood both with Haemoscreen and Haemoccult. A positive test was found with both methods in 35 patients (2.2%), a further 36 patients (2.3%) were positive only with Haemoscreen and 8 patients (0.5%) only with Haemoccult. In the first group six patients were found with colorectal carcinoma and 12 with large polyps, in the second group were one patient with carcinoma and four patients with polyps and in the third group two patients with polyps. Among patients with both tests negative carcinoma (n = 1) and polyps (n = 18) were diagnosed. Faecal testing was shown to be a simple and successful screening method for early recognition of intestinal carcinoma.
A study of the cytological appearances of benign and malignant colorectal adenomatous polyps is reported. The aim of the study was to characterize the cytological features of adenomatous polyps and predict the likelihood of malignancy using cytology. A five grade classification of colorectal cytology has been developed and the characteristic appearances of cells from adenomatous polyps are described. The reproducibility of cytological diagnosis based on this classification has been tested in 120 smears from normal mucosa and adenomatous polyps (including polyp cancers). Correlation with histology was achieved in 88% and correlation of the cytological diagnosis between two observers was achieved in 84%. We conclude that cytology can be used reliably as an adjunct to histology in the assessment of malignancy of adenomatous polyps.
Peutz-Jeghers syndrome (PSJ) is a relatively rare but well-recognized condition, with a prevalence of approximately one in 120,000 births in the USA. It is generally inherited as an autosomal dominant trait, although 35% of cases are new mutations. This disorder is characterized by melanocytic macules on the hands, feet, peri-oral skin and oral mucosa, and multiple gastrointestinal hamartomatous polyps. People with PSJ have an increased risk for developing a variety of malignant tumours. The aim of the present study was to report one case of PSJ in a 14-year-old boy with mucocutaneous pigmentation associated with duodenal hamartomatous polyps.
The results of investigation of the large intestine in 187 children were analysed. Of them, in 28 the terminal ileum was as well examined. In 38 patients with polyps and intestinal invagination, colonoscopy was performed in combination with endoscopy. Colonofibroscopy was used as a primary method of study to establish the causes of intestinal hemorrhage, colitis syndrome. The method has a high informative value, permits to extend the diagnostic and therapeutic possibilities in pediatric proctology.
The discharge and scraping from tumors of the rectum in 166 patients (cancer--103, simple polyp--32, proliferating polyp--17, villous polyp--5, malignant polyp--9) were studied at a time by means of various methods of cytoanalysis of suspension preparations (phase contrast, luminescent, supravital microscopy) and of smears (Pappenheim's staining, staining with hematoxilin-eosin, Papanicolaou method). On the grounds of the obtained data the phase optic, cytoluminescent and cytomorphologic patterns of various histological forms of cancer and polyps are set forth.
Colon cancer is a leading cause of death in the United States and is estimated to cause 56,500 deaths during 1998. Most cancers evolve from adenomatous polyps. Screening asymptomatic average-risk individuals is recommended to reduce colorectal cancer mortality by detection and removal of adenomatous polyps.
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