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[Autonomic dysfunction in diabetics].

The authors examined 120 patients with diabetes mellitus of the first and second types. Vegetative dysfunction was revealed in 84 patients (70%) that was manifested in disorders of the vegetative tone, vegetative reactivity. Different tests for assessment of the vegetative status and method of treatment of vegetative dysfunction are described.

Adolescent

[The role of autonomic dysfunction in the pathogenesis of lipid and lipoprotein metabolic disorders in patients with metabolic-alimentary obesity].

Obesity is a "disease of civilization" that leads to the formation of vascular pathology. Vegetodystonia, a heterogeneous syndrome both as regards the type and clinical course, is a pronounced clinical manifestation of obesity. The role of vegetodystonia in the formation of atherogenic potential of obesity has not been studied yet. 77 patients with metabolic alimentary obesity were examined for blood lipidograms as compared to the vegetative status and anthropometric data. Based on a correlation analysis performed, a relationship was discovered between the changes in the parameters indicated. The character of the correlation was determined by the type of vegetodystonia. The leading part in the formation of atherogenic potential is played by sympathoadrenal influences which are most manifest is permanent vegetovascular dystonia of the vagoinsular type. The treatment of obesity should be carried out with regard to the concrete variety of vegetative dysfunction.

Adolescent

[Autonomic dysfunction in multiple sclerosis (respiratory and cardiac disturbances) (author's transl)].

Except for rectal, vesical and sexual disorders almost nothing is known about disturbances of autonomic functions in multiple sclerosis. MS plaques, however, do not spare vegetative centres and spinal tracts. Therefore autonomic disorders are to be expected in other functional ranges as well. We could not confirm the study of Neubauer and Gundersen (1978) who found the short time variability and the long time variability of pulse rate to be significantly diminished in patients suffering from multiple sclerosis. Our investigation, however, revealed frequent occurrence of rigid, paradoxical and atactic courses of the patients' graphs obtained by "averaging" the pulse rate alterations dependent on respiration. We consider this to be an indication of cardio-respiratory hyposynergia in precision regulations. As compared with the normal control group the patients' respiratory rate was significantly raised, and this was almost exclusively due to an abbreviated time of inspiration. Concerning the pulse rate and the pulse-breathing quotient the patients did not differ significantly from the healthy controls. The findings in 40 MS patients (definite diagnosis) and in 40 healthy persons point to the fact that cardio-respiratory disorders are no rare occurrence.

Adult