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At least 163 records · Page 9Linked to original sources
PubMed1981

Are oral cathartics of value in optimizing the gallium scan? Concise communication.

The normal intestinal secretion of 9-15% of an administered dose of gallium-67 may prevent early detection of intra-abdominal disease. We randomized 50 patients to receive either no bowel preparation or 30 cc of milk of magnesia plus 5 cc of cascara. No significant difference was found between the two groups in frequency with which gallium interfered with readings or time to complete the study.

Abdomen↗
PubMed1994

Efficacy of magnesium citrate cathartic in pediatric toxic ingestions.

STUDY OBJECTIVE: To investigate the efficacy of magnesium citrate in reducing gastrointestinal transit time of activated charcoal in children. DESIGN: A prospective, randomized, clinical comparison of four magnesium doses. SETTING: Urban children's hospital emergency department. PARTICIPANTS: Children aged 1 month to 6 years who presented for management of an acute toxic ingestion. INTERVENTION: Each child received 1 g/kg activated charcoal combined with a randomly assigned dose of a 6% solution of magnesium citrate: 0 mL/kg, 4 mL/kg (standard recommended dose), 6 mL/kg, or 8 mL/kg. The primary outcome measure was the interval to first activated charcoal-containing stool, which was determined by follow-up telephone call or review of the medical record. RESULTS: Sixty-four children were enrolled. Median times to first charcoal stool were 19.5 hours (0 mL/kg), 13.0 hours (4 mL/kg), 14.0 hours (6 mL/kg), and 12.0 hours (8 mL/kg). Intergroup differences were significant by Kruskal-Wallis analysis of variance (P = .0035). CONCLUSION: Magnesium citrate reduces gastrointestinal transit times of activated charcoal stools when administered to children who receive activated charcoal for a toxic ingestion. Further study is needed to determine the clinical value of this reduction.

Antacids↗