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At least 163 records · Page 9Linked to original sources

[Use of a computer system in perinatal data collection].

We present a computer system for obstetrical and perinatological data collection. All deliveries of the years 1984, 1985, and 1986 have been collected with this data collection program, so that there is how a data base containing 7,975 data records. A relational data base was chosen for data collection and storage. Either off-line or on-line data collection is possible by medical users via menu monitoring. Various possibilities of use are described.

Birth Weight↗

["Hepar"--the clinical computer system and its diagnostic and didactic use].

The possibilities of application of the "Hepar" computer system in medical didactics are discussed. The usefulness of hepatological diagnosis assistance with information++ systems is described and the multistage schema of diagnostic management is presented. In the conclusions the advantages of this system in medicine teaching is stressed and its usefulness in clinical practice is outlined.

Computer Systems↗

Pharmacy-based computer system for monitoring and reporting drug interactions.

A pharmacy-based computer system for monitoring and reporting drug interactions is described, and physicians' responses to patient management suggestions generated by the system are reported. Using information from a commercially available drug-interaction database, a pharmacist chose 41 potentially interacting drug combinations to include in the pharmacy's automated system. A warning notice appears on the computer screen if one of these drug combinations is prescribed. Pharmacists who encounter these notices while entering medication orders telephone the prescribing physician if the combination represents a Class I interaction (immediate onset, major severity, established documentation); for Class II interactions, which have a delayed onset, a copy of the warning notice and suggestions for patient management are placed in the prescribing physician's mailbox. The system was evaluated during a three-month period in 1985 to determine physicians' responses to the patient management suggestions. A total of 927 patients had 1004 potentially interacting drug combinations prescribed for them. Changes in drug dosage were made in 44% of these instances, and in 75%, patients were monitored for the development of adverse clinical effects. A computerized drug-interaction monitoring system can help increase physicians' awareness of possibly interacting drug combinations and provide them with useful information about the clinical management of patients for whom such drug combinations have been prescribed.

Adolescent↗

Personal computer system for ECG ST-segment recognition based on neural networks.

A personal computer system for electrocardiogram (ECG) ST-segment recognition is developed based on neural networks. The system consists of a preprocessor, neural networks and a recogniser. The adaptive resonance theory (ART) is employed to implement the neural networks in the system, which self-organise in response to the input ECG. Competitive and co-operative interaction among neurons in the neural networks makes the system robust to noise. The preprocessor detects the R points and divides the ECG into cardiac cycles. Each cardiac cycle is fed into the neural networks. The neural networks then address the approximate locations of the J point and the onset of the T-wave (T(on)). The recogniser determines the respective ranges in which the J and T(on) points lie, based on the locations addressed. Within those ranges, the recogniser finds the exact locations of the J and T(on) points either by a change in the sign of the slope of the ECG, a zero slope or a significant change in the slope. The ST-segment is thus recognised as the portion of the ECG between the J and T(on) points. Finally, the appropriateness of the length of the ST-segment is evaluated by an evaluation rule. As the process goes on, the neural networks self-organise and learn the characteristics of the ECG patterns which vary with each patient.(ABSTRACT TRUNCATED AT 250 WORDS)

Computer Systems↗

A working in-house computer system for a general ophthalmology practice.

The authors describe their computer system, which was designed to support all of the information needs of their office and utilize the capabilities of the computer in every aspect of the practice. The system is now intricately involved in both clerical and medical activities. Problems of implementation were alleviated by the participation of the physicians and staff in designing the portions of the system with which they would be working; thus, the system is tailored to fit the needs of each individual.

Computers↗

Do you understand the role of software? It's the key to performance of laboratory computer systems.

Pathologists making decisions regarding computer applications in their laboratories need to understand all three aspects of computer technology: software, the user interface, and hardware. Of these, software may be the most important. This article identifies problems associated with software usage, taking into account contraints imposed by hardware and personnel, then suggests criteria for evaluating software. If pathologists are to derive maximum benefit from their investment in automated technology, they need to understand the intrinsic role of software in computer-based systems.

Computers↗

Computer system modelling muscle work.

In the work, an original computer system, called Muscle, is described. The Muscle allowed modelling of the whole thick filament with different arrangements of the myosin tails and myosin heads. Computer simulation and animation have revealed that only the model of the thick filament with asymmetrical configuration of the crossbridges has 3-fold rotational symmetry and assures matching between many thousands specific binding-sites on myosin heads and actin monomers. The Muscle delivered a number of arguments that the hypothesis of near parallel packing of the myosin tails, as well as oar-like or lever-arm-like work of the myosin crossbridges, is unfounded. We have presented advantages of the computer simulation in studies of complicated 3D molecular objects especially when direct observation is technically impossible.

Actins↗

Computer corner #15. The AAOS: request for computer system proposal.

The Committee on Computer Science and Practice Management of the American Academy of Orthopaedic Surgeons has provided an excellent format to ensure a happy relationship between the vendor and the orthopaedic office using this package. Problems in communication and understanding between the vendor and the orthopaedic surgeon will undoubtedly be significantly reduced. How the system will work is the vendor's problem, but what you want it to do for you is your problem, and both of these issues are addressed in these questionnaires. It is recommended in the computer package that three vendor proposals be invited. Since the most frequent cause of computer problems is improper evaluation of what functions the computer system must perform in order to meet the needs of the orthopaedic office, this series of questionnaires is important. In addition to recommending this computer package, I would also emphasize that if at all possible--in spite of what may appear to be an excellent system on paper--try to visit an office in which the system has been in use over the past six to 12 months.

Humans↗

Prevalidation of computer systems regulating medical device manufacturing processes.

When developing a computer system for regulating a medical device manufacturing process, it is advisable to incorporate validation criteria in the design and development of the system from the very beginning. Quality begins at the design stage and cannot be added at a later stage of system development. In this article, the author details the step-by-step process of software development that is recommended by the United States Food and Drug Administration (FDA) and utilized by the company in its development of a prevalidated sterilizer control system. By following FDA recommendations and using an external consultant to confirm validation, a prevalidated system can be supplied to the end-user. This provides the end-user with a number of significant benefits.

Computer-Aided Design↗

Decision-making laboratory computer systems as essential tools for achievement of total quality.

Areas other than the analytical process should be the focus of concern about quality issues in the laboratory because nearly 95% of errors occur at the nonanalytical front and back ends of the testing process. Until now, computer systems have been designed to handle the more predictable aspects of laboratory testing, necessitating that the infrequent and unpredictable data events be handled by manual systems. The manual systems are termed "workarounds" and indeed, because they occur sporadically, they are frequently not handled predictably. Here, I describe and give examples of an expert laboratory computer system that can be designed to handle both predictable and unpredictable data events without the use of manual workarounds. This expert system works in concert with a dynamic database allowing such data events to be detected in real time and handled predictably, thus providing a tool to address quality assurance issues throughout the testing process. The system performs up to 31 separate actions or tasks based on data events that in the past were handled by human workarounds.

Chemistry, Clinical↗

A modified composite video signal generator for the gamma 11 computing system.

Many nuclear medicine departments use the Gamma 11 computing system for image processing. In many cases, clinicians would like to display or record these images on equipment that has been designed for use with standard closed-circuit television or broadcast-type composite video signals. Unfortunately, the signals provided by the Gamma 11 differ from these standard signals in a number of important ways. The circuitry presented here converts the computer's output signals into a composite waveform that will properly drive virtually all equipment designed for closed-circuit television or standard broadcast-type applications.

Computers↗

A computer system for the numerical analysis of nonstress tests.

The development and clinical validation of a computer system for the numerical analysis of nonstress tests is reviewed, and recent improvements are reported. The analysis was developed by using a database of 73,802 nonstress test readings to provide a numerical definition of reactivity that is tailored to the gestational age of the fetus and independent of the presence of accelerations. When used at the bedside, the analysis minimizes monitoring time by alerting the operator when monitoring can be safely stopped because the fetal heart rate is normal. It also detects potentially sinister sinusoidal patterns and improves the quality of nonstress test readings by quantifying signal loss and, if significant, alerting the operator.

Cesarean Section↗

An automated computer system to support ultra high throughput SNP genotyping.

Celera Genomics has constructed an automated computer system to support ultra high-throughput SNP genotyping that satisfies the increasing demand that disease association studies are placing on current genotyping facilities. This system consists of the seamless integration of target SNP selection, automated oligo design, in silico assay quality validation, laboratory management of samples, reagents and plates, automated allele calling, optional manual review of autocalls, regular status reports, and linkage disequilibrium analysis. Celera has proven the system by generating over 2.5 million genotypes from more than 10,000 SNPs, and is approaching the target capacity of over 10,000 genotypes per machine per hour using limited human intervention with state of the art laboratory hardware.

Automation↗

Development and use of a computer system in a radiotherapy department: SISGRAD.

SISGRAD, the interactive computer system of the Antoine-Lacassagne Cancer Center Radiotherapy Department, has been operational since January 1982. It completes the computerized dosimetry system installed several years earlier and is fully integrated with the institution's central network. SISGRAD is in charge of surveillance of the radiotherapy treatments given by the Center's three radiotherapy units (1400 patients per year); it is also used for administrative purposes in the Department and physically connects all of the Department's operating stations. SISGRAD consists of a series of microcomputers connected to a common mass memory; each microcomputer is used as an intelligent console. SISGRAD was developed to guarantee that the treatments comply with prescriptions, to supply extemporaneous dosimetric data, to improve administrative work, and to supply banks with data for statistical analysis and research. SISGRAD actively intervenes to guarantee treatment quality and helps to improve therapy-related security factors. The present text describes the results of clinical use over a 4-year period. The consequences of integration of the system within the Department are analyzed, with special emphasis being placed on SISGRAD's role in the prevention and detection of errors in treatment prescription and delivery.

Database Management Systems↗