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PubMed1971

[Dumping syndrome].

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Dumping Syndrome↗
PubMed1970

[Dumping syndrome].

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Dumping Syndrome↗
PubMed1977

[Dumping syndrome].

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Dumping Syndrome↗
PubMedDate not supplied

[Characteristics of the motor function of the gallbladder in the dumping syndrome and their importance in establishing a therapeutic diet].

In 76 patients suffering from the dumping syndrome following gastric resection in connection with peptic ulcer the motor function of the gallbladder and gastric stump was studied. Investigations ascertained the existence of a direct relationship between the type of the gallbladder dyskinesia and evacuation periods from the gastric stump. The authors consider the hypermotor dyskinesia of the gallbladder combined with an accelerated evacuation from the stump to be an optimal combination after excision of the stomach. On the other hand, the hypomotor dyskinesia of the gallbladder with an accelerated emptying of the gastric stump was regarded as am explicit pathology demanding persistent curative measures. Principles of pathogenetic dietotherapy have been evolved.

Dumping Syndrome↗
PubMed1996

Dumping syndrome following Nissen fundoplication, diagnosis, and treatment.

We evaluated the prevalence, diagnosis, and treatment of dumping syndrome (DS) following Nissen fundoplication in 50 consecutive infants and children who underwent the operation for gastroesophageal reflux. Examination included a preoperative dietary assessment with emphasis on specific postprandial clinical symptoms and technetium scintigraphy to evaluate gastric emptying. In the immediate postoperative period, postprandial glucose levels were examined in all patients with symptoms clinically suggestive of DS. In the late postoperative period (6 months to 5.5 years), all patients with more than one specific clinical symptom of DS were further evaluated by glucose tolerance test (GTT), HbA1C levels, and gastric technetium scintigraphy. DS was diagnosed in 15 patients (30%). Five patients had immediate severe DS (SDS), and 10 in the late postoperative course had latent postoperative DS (LDS). In all patients with DS, preoperative and postoperative gastric emptying scan T1/2 did not show any statistical significance. High levels of HbA1C ranging from 7.9 to 9% (mean, 8.25 +/- 0.5) were found in only three patients. Treatment included parenteral nutrition in one patient. All the others were successfully managed with nutritional manipulation alone, using a combination of lactose-free formula and fat emulsion. In patients whose postprandial symptoms persisted, pectin 5-15 g/day divided into six doses was added to the diet. Following 6 months of dietary treatment, the postprandial normoglycomic response was restored. Eleven patients experienced complete resolution of symptoms (78.5%), and three patients (21.4%) showed significant clinical improvement. This study indicates that DS is a common complication following Nissen fundoplication. The GTT is the most reliable examination for establishing the diagnosis. Treatment is simple and effective. The technetium gastric emptying scan and HbA1C level do not play a significant role in the diagnosis.

Adolescent↗
PubMed1979

A glycoside-hydrolase inhibitor in treatment of dumping syndrome.

BAY g 5421, a glycoside-hydrolase inhibitor, produced symptomatic improvement in ten patients with the dumping syndrome. 100 mg BAY g 5421, given before a 50 g sucrose meal, produced pronounced attenuation of both hyperglycaemic and hypoglycaemic phases of plasma glucose levels; and it greatly reduced the rise in plasma levels of gastric inhibitory polypeptide and insulin. Gastric emptying, studied simultaneously by an isotopic method, showed little difference between tests, suggesting that the improvement achieved was not mediated by slowing gastric emptying.

Adult↗