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Introduction: reading the human genome: Gothic tale or happy ending?
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Is data-hoarding slowing the assault on pathogens?
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'Playing chicken' over gene markers.
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Physicians wary of scheme to pool Icelanders' genetic data.
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A second private genome project.
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DNA studies challenge the meaning of race.
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New goals for the U.S. Human Genome Project: 1998-2003.
The Human Genome Project has successfully completed all the major goals in its current 5-year plan, covering the period 1993-98. A new plan, for 1998-2003, is presented, in which human DNA sequencing will be the major emphasis. An ambitious schedule has been set to complete the full sequence by the end of 2003, 2 years ahead of previous projections. In the course of completing the sequence, a "working draft" of the human sequence will be produced by the end of 2001. The plan also includes goals for sequencing technology development; for studying human genome sequence variation; for developing technology for functional genomics; for completing the sequence of Caenorhabditis elegans and Drosophila melanogaster and starting the mouse genome; for studying the ethical, legal, and social implications of genome research; for bioinformatics and computational studies; and for training of genome scientists.
Opponents criticize Iceland's database.
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Icelandic health records.
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Iceland OKs private health databank.
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Policy forum: health care delivery. Building populations genetics resources using the U.K. NHS.
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Storm brews over gene bank of Estonian population.
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Human genetics. Start-up claims piece of Iceland gene pie.
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Epidemiology. U.K. plans major medical DNA database.
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Genome sequencing. Talks of public-private deal end in acrimony.
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In the crossfire: Collins on genomes, patents, and 'rivalry'. Interview by Eliot Marshall, Elizabeth Pennisi, and Leslie Roberts.
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Biobanks. Population databases boom, from Iceland to the U.S.
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