SEARCH · PubMed Health

Results for “Dentin Sensitivity”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 163 records · Page 9Linked to original sources

PubMed1990

The effectiveness of a patient-applied tooth desensitizing gel. A pilot study.

Potassium nitrate has been found to be an effective ingredient for reducing dentinal hypersensitivity. The purpose of this study was to evaluate the effectiveness of a patient-applied 10% potassium nitrate glycerine-based gel in decreasing dentinal sensitivity on cold on teeth with exposed dentin apical to the cemento-enamel junction, 12 patients, each having 3 hypersensitive teeth, were tested. The patients were divided into 3 treatment groups: group 1 was treated with a glycerine-based 10% potassium nitrate gel: group 2 was treated with a glycerine gel without potassium nitrate; and group 3 received no gel and no treatment (control). Following brushing and flossing, groups 1 and 2 applied the gel to the test teeth using custom-made soft acrylic trays, for a period of 5 min/day for 4 weeks. Patient responses to cold water stimuli of 20 degrees C, 10 degrees C and 0 degrees C, were measured at baseline (week 0), then at 1-, 2-, 3- and 4-week intervals. Group 1 patients showed a significant decrease in sensitivity to cold at week 2 only. The group 2 patients showed a significant decrease in sensitivity to cold after 3 and 4 weeks. A statistically significant decrease in sensitivity was noted between group 2 and group 3 patients at week 3. The most sustained decrease in sensitivity to cold was found on teeth treated with plain glycerine.

Administration, Topical↗

PubMed2000

Dentine bonding systems: 2. Clinical uses.

As the reliability of dentine bonding agents has improved, the clinical uses of these systems has increased and now include the bonding of directly and indirectly constructed restorations, amalgam bonding and treatment of dentinal sensitivity. Areas of potential use which require further evaluation include pulp capping and the attachment of fractured tooth fragments.

Adhesives↗

PubMed2000

Effect of dentin desensitizers and dentin bonding agents on dentin permeability.

PURPOSE: To determine the effect of dentin desensitizing agents (oxalates and glutaraldehyde) and dentin bonding agents, with and without resin-based composite (RBC) on dentin permeability and morphology of the dentin surface. The influence of saliva and toothbrushing on these agents was also evaluated. MATERIALS AND METHODS: Radicular dentin discs +/-1 mm thick were obtained from extracted human teeth. The thickness of the discs was standardized by grinding them with 600 grit silicon carbide powder. Both pulpal and periodontal surfaces of the discs were treated with 6% citric acid for 2 min prior to the baseline measurement of dentin permeability. Permeability was measured for the discs, using a split-chamber apparatus, at four different time points: at baseline, after treatment with each desensitizing modality, after 24 hrs of saliva immersion and after simulated toothbrushing equivalent to 3 weeks of normal brushing. The treatment modalities were: Sensodyne Dentin Desensitizer, Gluma Dentin Desensitizer, All-Bond DS (primers without etching), Etch+Primers (All-Bond 2 system), Etch+Primers+Adhesive and Etch+Primers+Adhesive+RBC (AElite Flo). Radicular dentin discs were prepared separately for scanning electron microscopy (SEM). One group was left untreated as the control group. Discs in the other groups were treated with the modalities listed above. One disc from each group was viewed under the SEM after treatment with the desensitizing modality. The second disc in each group was viewed after 24 hrs of saliva immersion following desensitizing treatment and the third disc after 3 weeks of simulated toothbrushing following desensitizing treatment and saliva immersion. RESULTS: The greatest reduction in permeability was caused by All-Bond DS followed by Sensodyne Dentin Desensitizer and Etch+Primers+Adhesive+RBC. Gluma Dentin Desensitizer, Etch+Primers, and Etch+Primers+Adhesive did not reduce permeability by a significant amount. Saliva immersion increased permeability significantly only for the Gluma and Etch+Primers+Adhesive groups. There was a trend towards increase in permeability after toothbrushing; however, this increase was not statistically significant for any group (P > 0.05). Thus, placement of primers without etching (All-Bond DS) reduced permeability more than any other treatment modality. These data indicate that etching a sensitive dentin area may be appropriate only if RBC is to be placed in the area. Exposure to saliva and toothbrushing countered the decrease in permeability caused by dedicated desensitizers and dentin bonding agents. The SEM micrographs revealed that in most cases, form corroborated function and the morphology of the dentin surface corresponded to the dentin permeability values.

Acid Etching, Dental↗

PubMed2006

Morphometric analysis of pulpal myelinated nerve fibers in human teeth with chronic periodontitis and root sensitivity.

BACKGROUND: The reasons why root sensitivity occurs in some periodontally diseased teeth are still unknown. It is possible that root sensitivity may be related to changes of intradental myelinated nerve fibers, which are responsible for dentine sensitivity. OBJECTIVE: The aim of this study was to define the pattern of myelinated nerve fiber changes in the pulps of teeth with and without root sensitivity in the presence of chronic periodontitis. MATERIALS AND METHODS: A total of 33 cross-sectioned human dental pulp specimens were collected from noncarious, intact, permanent teeth sensitive to electric and thermal (cold) stimulus (10 hypersensitive teeth with chronic periodontitis (HTPP group), 15 nonsensitive teeth with chronic periodontitis (NTPP group), and 8 nonsensitive teeth with healthy periodontium (control group)). The morphometric parameters were estimated using light microscopy and image-analyzing computer program Image-Pro Plus. RESULTS: The means of myelinated nerve fiber density, fiber and axon diameter, area, perimeter, length, width, g ratio, index of circularity, and myelin sheath thickness in NTPP group significantly differed from HTPP group and the control group teeth (p<0.001). The great reduction in the density of myelinated nerve fibers in NTPP group was accompanied by unequal decrease in the number of very large-diameter myelinated nerve fibers. The mean values of morphometric parameters of all myelinated nerve fibers in HTPP group were almost the same as those in the control teeth, and no significant difference was observed. CONCLUSION: The findings of the present study suggest that the reason for enhanced root sensitivity has likely nothing to do with changes of the innervation of myelinated nerves in the dental pulp. While, decreased sensitivity of periodontally diseased teeth may be related to the degeneration of myelinated nerve fibers in the pulp.

Adult↗

PubMed1992

The role of selected cations in the desensitization of intradental nerves.

Dentinal sensitivity is a common complaint of patients. Removal of cementum or enamel leaves the dentin exposed allowing various stimuli to produce fluid movement through the dentinal tubules. These fluid movements are believed to activate pulpal sensory nerves leading to pain. Various therapeutic approaches have been investigated to treat this problem. Resins, fluoride compounds and oxalate solutions have been used to block the dentinal tubules. KNO3 and SrCl2 are active ingredients in desensitizing tooth pastes but neither compound reduces the permeability of dentine. The ability of various solutions to decrease hypertonic (3M NaCl) evoked nerve activity was tested in the canine teeth of anesthetized cats. Excitatory and desensitizing solutions were placed into a deep dentinal cavity prepared over the incisal pulp horn. An electrode used to record nerve activity was also placed into this deep cavity. KNO3 and other K+ ion containing solutions elicit a biphasic effect on nerve activity. Immediately following application of these solutions into the deep dentinal cavity there is a brief burst of high frequency spike activity. Following this brief period of excitation, the intradental nerves are silent and respond weakly to hypertonic NaCl. CaCl2 and other divalent cation solutions also inhibit hypertonic NaCl induced nerve activity, but have a weaker effect than that exerted by K+. These observations can be explained based on the effects of various ions on nerve excitability. Increasing the K+ ion concentration in the vicinity of the dentinal nerve terminal depolarize and activates the nerve fibers. Following a prolonged period of depolarization the action potential mechanism is inactivated. Divalent cation solutions stabilize the nerve membrane without changing the membrane potential. Desensitizing solutions do not decrease nerve activity by an effect on pulpal blood flow. This experimental model does not entirely explain the clinical action of these desensitizing agents. The role of inflammation in hypersensitivity and dental pain is currently being investigated.

Animals↗

PubMed1999

Clinical efficacy of two dentin desensitizing agents.

PURPOSE: To compare the clinical effect over 3 months of two commercially available desensitizing agents on the level of discomfort of patients with complaints of dentin sensitivity. MATERIALS AND METHODS: An oxalate-containing pre-polymerized resin suspension (Pain-Free), a 0.7% fluoride solution (DentinBloc), and a distilled water placebo were compared in a clinical setting. Ten volunteer patients exhibiting three or more teeth that were sensitive to touch and to a stream of forced air were enrolled in the study (52 teeth total). Each patient's level of sensitivity to tactile stimuli and to a forced air stream was recorded using a visual analog scale (VAS). The tactile stimulus was a metal probe rubbed across the exposed dentin with a constant pressure of 40 grams. A 1-second blast of air from a dental unit air syringe was used to generate the air stream. The desensitizing agents were applied according to manufacturers' guidelines. Sensitivity measurements were recorded at baseline, immediately after treatment, at 1 week, 1 month, and at 3 months. VAS pain scores were analyzed using a repeated measures ANOVA (alpha = 0.05). RESULTS: The pre-polymerized resin suspension (Pain-Free), the fluoride-containing solution (DentinBloc), and the placebo all decreased dentin sensitivity. No significant difference was found among the desensitizing agents at any time period (P > 0.05).

Adult↗

PubMedDate not supplied

Evaluation of the desensitizing effect of Gluma Dentin Bond on teeth prepared for complete-coverage restorations.

This clinical trial assessed the ability of Gluma Dentin Bond to inhibit dentinal sensitivity in teeth prepared to receive complete cast restorations. Twenty patients provided 76 teeth for the study. Following tooth preparation, dentinal surfaces were coated with either sterile water (control) or two 30-second applications of Gluma Dentin Bond (test) on either intact or removed smear layers. Patients were recalled after 14 days for a test of sensitivity of the prepared dentin to compressed air, osmotic stimulus (saturated CaCl2 solution), and tactile stimulation via a scratch test under controlled loads. A significantly lower number of teeth responded to the test stimuli for both Gluma groups when compared to the controls (P less than .01). No difference was noted between teeth with smear layers intact or removed prior to treatment with Gluma.

Chi-Square Distribution↗

PubMed1993

Pilot clinical study of a fluoride resin and conditioning paste for desensitising dentine.

The clinical trial was carried out on 34 'hypersensitive' teeth in 10 subjects. Dentine sensitivity was measured as the pain perception thresholds to controlled air and probe stimuli. In each subject, pairs of teeth of comparable initial sensitivity were randomly assigned to a test (T) or control (C) treatment. All teeth were cleaned and a conditioning paste applied. Group T was treated with a topically-applied light-cured resin; Group C received a placebo, sham light-cured. Air sensitivity was remeasured after treatment, and the procedures were repeated after 1, 2, and 3 weeks. When comparing air thresholds before and after treatment at each visit, the test agent caused significantly greater reduction in sensitivity than the control. The median increase in air threshold in the test group was 2.5 s at visit no. 1, 1.3 s at visit no. 2 and 0.8 s at visit no. 3. Comparisons of the initial thresholds at each visit showed no significant long-term changes in sensitivity in either group.

Administration, Topical↗

PubMed1984

Dentin permeability. Effects of desensitizing dentifrices in vitro.

Patients using placebo dentifrices in clinical trials usually show a significant decrease in dentin sensitivity over a 2- to 4-week period. If their sensitivity were due to hydrodynamic fluid movement, then the results suggest that there was a decrease in their dentin permeability. This hypothesis was tested in vitro by measuring the ease with which fluid could flow (i.e., hydraulic conductance) across dentin discs before and after brushing the discs with a variety of dentifrices, including most of the marketed densensitizing dentifrices. All dentifrices decreased the hydraulic conductance of dentin. An experimental dentifrice containing oxalate as the active ingredient was far more effective than any of the marketed dentifrices. The results tend to support the hypothesis that, at least part of the reduction in clinical sensitivity in patients with hypersensitive dentin is due to the abrasive action of the dentifrice.

Dentifrices↗

PubMed2004

Effect of sodium hypochlorite treatment on the molecular composition and morphology of human coronal dentin.

PURPOSE: The aim of the present study was to evaluate the deproteination potential of 5% aqueous NaOCl solution applied by rubbing action on the molecular composition and morphology of smear-layer covered and acid-etched human coronal dentin surfaces. MATERIALS AND METHODS: Paired specimens (n = 4 x 2 per group) of acid-etched (Group A) and smear-layer covered (Group B) human coronal dentin surfaces were sequentially treated with the NaOCl solution for time intervals ranging from 5 s to 120 s and analyzed by reflectance FTIR microspectroscopy and tapping mode atomic force microscopy. The changes in the mineral (v4 P-O stretching vibrations) to matrix (C = O stretching vibrations of amide I) peak area ratios and in the Ra roughness parameter were used to quantify the effect of treatment. Two-way ANOVA and Dunn's tests were used to assess the differences within each group and between groups (a = 0.05). RESULTS: In both groups, NaOCl treatment reduced organic matrix (amide I, II, III peaks), but did not affect carbonates and phosphates. In group A, the rate of deproteination was slow, and reached a peak value after 120 s. Tubule orifices became visible after 40 s of treatment; after 120 s, excessive porosity was detected, with Ra values presenting no statistically significant difference from group B. In group B after 10 s, the extent of deproteination was enhanced, reaching a plateau between 30 s and 60 s, and attaining a maximum after 120 s. Tubule diameter, intertubular porosity, and Ra were increased; intertubular dentin area was reduced. For both groups after 40 s of treatment, the mineral to matrix ratio recorded was similar to smear-layer-free sectioned dentin. CONCLUSION: The results of the present study imply that deproteination of mineralized or acid-etched dentin surfaces within a clinically relevant time frame may provide methods for bonding to dentin alternative to conventional technique-sensitive dentin hybridization.

Acid Etching, Dental↗

PubMed2001

The effects of oxalate-containing products on the exposed dentine surface: an SEM investigation.

In-office products containing oxalates have been claimed to be clinically effective in reducing dentine sensitivity, although there has been limited supporting clinical data. The rationale for their use appears to be based on their potential to act as occluding and/or nerve desensitizing agents. Four commercially available oxalate-containing products were applied to etched dentine discs and the extent of tubule occlusion was observed by scanning electron microscopy. Tenure Quick (aluminium oxalate), Sensodyne Sealant (ferric oxalate) and MS Coat (oxalic acid) covered the dentine surface and occluded the tubules. However, Butler Protect (potassium oxalate) did not cover the surface to any great extent but provided some occlusion. The presence of oxalates after application to glass slides and dentine discs was examined using thin film X-ray diffraction. From samples on glass, only potassium oxalate could be clearly identified (JCPDS 14-0845). No oxalate was detected on dentine discs in either thin film geometry or standard theta two theta mode. We have demonstrated that professionally applied in-office products containing oxalate are capable of covering the dentine surface and/or occluding the tubules to varying degrees. However, X-ray diffraction analysis was unable to confirm the oxalate profile for all products as described in the available commercial literature.

Acid Etching, Dental↗

PubMed1993

The effectiveness of the Nd:YAG laser in the treatment of dental hypersensitivity.

Dentin hypersensitivity is one of the most painful and least predictably treated chronic conditions in dentistry. The effectiveness of laser therapy in the reduction of dentin hypersensitivity and its effects on pulpal vitality were studied. Nineteen subjects participated in the randomized, double-blind study, and were followed up for three months. Two sites were treated. One received helium neon (He:Ne) laser treatment and the other received He:Ne plus Nd:YAG (He:Ne+Nd:YAG) laser treatment. Laser treatment consisted of 30 millijoules (mJ) to 100 mJ per pulse, at 10 pulses per second (pps) in increments of 10-40 seconds each over a total treatment time of less than two minutes, without local anesthesia. Hypersensitivity was assessed by mechanical stimulus (using a sharp explorer), and thermal stimulus (using a blast of cold air from a dental syringe). Pulpal vitality was measured using an electrical stimulus. The results indicate that immediately following laser treatment and for three months thereafter, the subjects' perceived level of discomfort decreased. He:Ne treatment reduced dentin hypersensitivity to air by 63 per cent and to mechanical stimulation by 61 per cent over three months. The He:Ne + Nd:YAG treatment reduced dentin sensitivity to air by 58 per cent and to mechanical stimulation by 61 per cent. All teeth remained vital after laser treatment, with no adverse reactions or complications. He:Ne and He:Ne + Nd:YAG laser treatment can be used to reduce dentin hypersensitivity without detrimental pulpal effects.

Adult↗

PubMed2003

Scanning electron microscopy evaluation of the link between a new dentinal desensitizer and dentine.

AIM: The purpose of this study was to evaluate the interaction of a novel dentinal desensitizer Twin Pro with enamel-dentinal adhesive preparations or filling materials and dentine using scanning electron microscopy (SEM) technology. METHODS: Black's I class cavities were drilled extracted molar teeth free of caries or fissures, and the cavities disinfected. The specimens were divided into 4 groups of 2 teeth each treated as follows: Group A: Twin Pro, fluid (Tetric-Flow Vivadent) and micro-hybrid (Tetric-Ceram Vivadent) composites placed on the etched (Liner Bond 2V Clearfil) cavities. Group B: Twin Pro, PQ1-Ultradent loaded Primer-Bonding plus fluid and micro-hybrid composites applied to the acid-etched (37% orthophosphoric acid) cavities. Group C: Twin Pro plus Silver amalgam alloy (Phasealloy- Sybram Kerr). Group D (control group): self-etching primer plus fluid and micro-hybrid composite. Specimens were investigated by SEM. RESULTS: The results obtained in all groups show that the application of Twin Pro does not alter the adhesiveness of the restorative composite materials to the dental wall. In fact the desensitizer and the adhesive layers are indistinguishable at SEM observation, and well adherent to the dentinal surface of the cavities. CONCLUSION: The results of SEM investigations show that Twin Pro does not decrease the adhesion of restorative materials to the tooth surface, as it establishes an efficient interconnection with the different materials used, and it forms a uniform layer covering and occluding dentine tubules, and this might constitute an efficacious sealing of dentinal tubules which possibly contribute to decrease dentinal sensitivity to environmental nociceptive stimuli.

Acrylic Resins↗

PubMed2005

Laser therapy in the treatment of dentine hypersensitivity.

Cervical dentine hypersensitivity is the most frequent complaint among reported odontalgias. Thus, this study evaluated the effectiveness of two types of lasers (660 nm wavelength red, and 830 nm wavelength infrared) as dentine desensitizers, as well as both the immediate and late therapeutic effects in individuals 25 to 45 years of age. A total of 40 teeth with cervical exposure were treated in 4 sessions. They were divided into 2 groups according to treatment. A 660 nm wavelength red diode laser and an 830 nm wavelength infrared diode laser were used. Dentine sensitivity to cold nociceptive stimulus was evaluated by means of a pain numeric scale from zero to 10 before each treatment session, at 15 and 30 min after irradiation, and in a follow-up period of 15, 30 and 60 days after the end of treatment. Significant levels of dentinal desensitization were only found in patients ranging in age from 25 to 35 years. The 660 nm red diode laser was more effective than the 830 nm infrared laser and a higher level of desensitization was observed at the 15 and 30 minute post-irradiation examinations. The immediate and late therapeutic effects of the 660 nm red diode laser were more evident in 25-35-year-old patients compared with those of the 830 nm infrared diode laser, in terms of the different age groups.

Adult↗

PubMed1995

Neural elements in dental pulp and dentin.

This article addresses the structural and quantitative aspects of human tooth innervation and briefly considers the functions and clinical relevance of tooth axons. The classification of peripheral axons, the pulpal and dentinal innervation, and the theories of dentin sensitivity are discussed. Quantitative studies on tooth innervation are also reviewed. Human premolars receive about 2300 axons at the root-apex of which about 13% are myelinated and 87% are nonmyelinated fibers. Most apical myelinated axons are fast-conducting A delta-fibers with their receptive fields located at the pulpal periphery and inner dentin. These fibers are probably activated by a hydrodynamic mechanism and conduct impulses that are perceived as a short well-localized sharp pain. Most C-fibers are slow-conducting fine sensory afferents with their receptive fields located in the pulp and transmit impulses that are experienced as dull poorly localized and lingering pain. In addition to the nociceptive alarm signaling, the intradental sensory axons may play a regulatory role in the maintenance and repair of the pulpodentinal complex.

Animals↗

PubMed1993

Effect of periodontal root planing on dentin permeability.

The purpose of this study was to quantitate the effects of root planing on the permeability of human root dentin in vitro. Unerupted 3rd molars were used. The crowns were removed and longitudinal slices made of the root. The hydraulic conductance of the root dentin was measured before and after root planing, acid etching and potassium oxalate application using a fluid filtration method. The results showed that root planing creates a smear layer that reduces the permeability of the underlying dentin. However, this smear layer is acid labile. Thus, root planing may ultimately cause increased dentin permeability and the associated sequelae of sensitive dentin, bacterial invasion of tubules, reduced periodontal reattachment and pulpal irritation.

Acid Etching, Dental↗

PubMed1991

Effectiveness of chlorhexidine and sodium fluoride in reducing dentin hypersensitivity.

This investigation was conducted to evaluate the effect of chlorhexidine, sodium fluoride, and sequential rinses of chlorhexidine (Cx) and sodium fluoride (NaF) on dentin hypersensitivity. Forty-four adult patients with dentin hypersensitivity on three teeth were randomly assigned to receive one of four treatment rinses: (1) placebo; (2) 0.12% Cx; (3) 0.2% NaF; or (4) 0.12% Cx plus 0.2 NaF. Patients' responses to cold stimulation were recorded at baseline, two weeks, and four weeks. Pain response was quantified by applying successively decreasing temperature intervals of water (20 degrees C, 15 degrees C, 10 degrees C, 5 degrees C, and 0 degrees C) to exposed dentin. Plaque Index (Silness and Löe) was recorded at baseline only. Data on dentin sensitivity over time were analyzed using a repeated measures ANOVA. This ANOVA was conducted to generate an error term for calculation of Dunn's multiple mean comparison test. A Spearman rank order test was computed to assess correlation between plaque and hypersensitivity at baseline. Results showed the Cx and NaF rinses alone significantly reduced hypersensitivity (p less than .01) at four weeks compared to baseline. Sequential Cx and NaF rinses significantly decreased sensitivity (p less than .01) at both the two- and four-week intervals compared to baseline. At the four-week interval, the sequential Cx/NaF rinse group showed a significantly greater reduction (p less than .01) in hypersensitivity response when compared to placebo. Cx alone, or NaF alone groups. A moderate, positive correlation (r = 0.55) was demonstrated between plaque and dentin hypersensitivity. This was statistically significant at the (p less than .05) level.

Adult↗

PubMedDate not supplied

The effectiveness of electronic dental anesthesia in children.

This study compared the effectiveness of traditional local anesthesia with a Transcutaneous Electrical Nerve Stimulation unit that controls pain via electronic dental anesthesia for restorative dental procedures in 6- to 12-year-old children. The sample included 27 children who had two antimere teeth that required restorations of similar size (preventive resin restorations). In each case, the cavity preparation extended into dentin. One of the teeth was treated with conventional local anesthesia and the other with EDA. Selecting which tooth and which method to complete first was done randomly. Both restorations were done at the same appointment. Throughout the procedure, the child was asked to assess the level of discomfort using the Eland Color Scale, which allowed the children to draw on their past painful experiences to judge the level of pain they perceived. The patients demonstrated no overall significant difference in pain perception between the two modalities of treatment, regarding dentin sensitivity and rubber dam clamp replacement. When asked which method they preferred after the study, 78% of the patients chose EDA over local anesthesia.

Anesthesia, Dental↗