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At least 163 records · Page 9Linked to original sources
PubMed2006

Prevention of nosocomial infection during dermoscopy?

BACKGROUND: Dermatoscopes are applied directly to cutaneous or mucocutaneous surfaces with immersion fluid (IF) such as oil or alcohol to reduce light reflection. Recently, Staphylococcus aureus has been isolated from dermatosopes that used mineral oil as the IF. Thus, dermatoscopes might be a potential source of nosocomial infection. OBJECTIVE: In this study we propose the use of an alcohol-based antibacterial gel to reduce nosocomial infection transmission while optimizing optical resolution during dermatoscopic examination. MATERIALS AND METHODS: Aerobic bacterial cultures were performed on three dermatoscopes used in an outpatient setting after routine examination of 31 patients with an alcohol-based antibacterial gel as IF. RESULTS: There was no bacterial growth after using the antibacterial gel with the dermatoscopes. The optical resolution for the antibacterial gel appeared equal to the 'dermatoscopy oil' and superior to alcohol wipes. CONCLUSIONS: Alcohol-based antibacterial gel appears to inhibit bacterial colonization while offering excellent optical resolution during dermoscopic examination. The use of alcohol-based IF appears to obviate the risk of nosocomial infections.

Cross Infection↗
PubMed2005

Modality independent elastography (MIE): potential applications in dermoscopy.

The use of palpation information for skin disease characterization is not as commonly used as in other soft tissues, although mechanical differences within lesions have been noted. For example, regions of hyperkeratosis have the potential to transform into cancerous lesions and likely feature different material properties from those of surrounding normal tissue due to varying cytoarchitecture. As a result, the spatial distribution of lesion mechanical properties may serve to assist a diagnosis or enhance visualization of the complete extent of a cancerous region, i.e., accurate information regarding the margins of disease for surgical therapy. In this work, a multiresolution extension to a novel elastographic imaging method called Modality Independent Elastography (MIE) is used to characterize the mechanical properties of a skin-like phantom embedded with a mock stiff lesion. Simulation studies were also performed to investigate the potential for characterizing realistic melanoma lesions. Elasticity image reconstructions from the phantom experiments localized the stiff inclusion and had good correlation between the Young's modulus contrast ratio and experimental measurements from material testing. In addition, multiresolution MIE was shown to be a more robust framework than its single-resolution version. Results from the melanoma simulation demonstrate the potential for using multiresolution MIE with dermoscopic images.

Algorithms↗