[Therapeutic possibilities in chronic renal insufficiency with growth disorder in children].
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This study assessed the psychometric properties of a recently developed health-related quality of life (HRQOL) instrument (Vécu et Santé Perçue de l'Adolescent -Malade, VSP-AM) in 172 adolescents receiving growth hormone. The VSP-AM was cross-culturally adapted into English and tested for internal consistency (alpha=0.78-0.89 subscales, 0.74 Summary Score), construct and criterion validity, and responsiveness. Correlations with other scales demonstrated convergent validity. Adolescents who reported HRQOL as high or low had significantly different scores (all p<0.001). Adolescents receiving growth hormone therapy differed significantly from adolescents with medical, surgical or psychiatric disorders. The VSP-AM shows reliability and validity for HRQOL measurement in adolescents with growth disorders.
The paper presents several remarks on the diagnosis of the growth disturbances in the child, with emphasis on the dwarfism entity by emotional deprivation. The study was performed on two comparative groups. The age of the children ranged between 1 and 3 years. 22 cases (49%) were of deficiency dwarfism, 5 cases of primordial dwarfism (12%), 6 cases (14%) of dwarfism secondary to organic lesions (meningitis, blue asphyxia at birth), 4 cases (8%) of constitutional dwarfism, 8 cases (16%) of idiopathic dwarfism, possible by emotional deprivation. The paper classifies the main causes of dwarfism, reports the diagnosis criteria and emphasizes the importance of detecting, as early as possible, the dwarfism by emotional deprivation, since these disturbances reverse when the child enters a corresponding affective medium.
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