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PubMed2003

Behçet's disease: from Hippocrates to the third millennium.

Behçet's disease (BD) is characterised by recurrent episodes of orogenital aphthae, systemic vasculitis, and systemic and retinal venous thrombosis. An association between HLA-B51 and BD was first identified over 20 years ago, but recently identified gene associations implicate regions both within and without the MHC in the immunological events underlying the lesions in BD. These include allelic variants within the tumour necrosis factor gene region and within the MHC class I chain related gene region, the factor V Leiden mutation, which is associated with retinal vascular occlusion, and alleles of the intercellular adhesion molecule gene. No single causative gene for BD has emerged; the evidence indicates that the underlying immune events in BD are triggered by a microbial antigen and subsequently driven by genetic influences which control leucocyte behaviour and the coagulation pathways. Knowledge of these risk factors may permit a more accurate prognosis for a given patient, and identify new pathways for more targeted intervention than is currently available.

Behcet Syndrome↗
PubMed2003

[How holistic is health?--from Hippocrates and Plato to a future sociopsychosomatic situational therapy].

To be with others is helpful for the recovery from illness. It has been shown that this is true not only in human relations but also, for instance, in relating oneself to trees as well. This implies that health is not an individual but a social property. Like in Hippocratic and Platonic medicine illness means to have got out of oneself or out of one's nature in the widest - even cosmic - sense. The basic task of complementary and natural medicine is to prevent just this; to cure diseases can only be second-class.

Complementary Therapies↗